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ARIC Publications

2020
Meyer ML, Klein BE, Klein R, et al. "Central arterial stiffness and retinal vessel calibers: the Atherosclerosis Risk in Communities Study-Neurocognitive Study." J Hypertens. 2020;38(2):266-273.
Sargurupremraj M, Suzuki H, Jian X, et al. "Cerebral small vessel disease genomics and its implications across the lifespan." Nat Commun. 2020;11(1):6285.
Foti K, Matsushita K, Koton S, et al. "Changes in hypertension control in a community-based population of older adults, 2011-2013 to 2016-2017." Am J Hypertens. 2020.
Sonsin-Diaz N, Gottesman RF, Fracica E, Walston J, B Windham G, Knopman DS. "Chronic Systemic Inflammation Is Associated With Symptoms of Late-Life Depression: The ARIC Study." Am J Geriatr Psychiatry. 2020;28(1):87-98.
Alonso A, Rooney MR, Chen LYee, et al. "Circulating electrolytes and the prevalence of atrial fibrillation and supraventricular ectopy: The Atherosclerosis Risk in Communities (ARIC) study." Nutr Metab Cardiovasc Dis. 2020;30(7):1121-1129.
Gore MOdette, Ayers CR, Khera A, et al. "Combining Biomarkers and Imaging for Short-Term Assessment of Cardiovascular Disease Risk in Apparently Healthy Adults." J Am Heart Assoc. 2020;9(15):e015410.
Armstrong NJ, Mather KA, Sargurupremraj M, et al. "Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities." Stroke. 2020;51(7):2111-2121.
Zhao D, Guallar E, Vaidya D, et al. "Cyclic Guanosine Monophosphate and Risk of Incident Heart Failure and Other Cardiovascular Events: the ARIC Study." J Am Heart Assoc. 2020;9(2):e013966.
Li C, Mou C, Swartz MD, Yu B, Bai Y, Tu Y. "dbMTS: A comprehensive database of putative human microRNA target site SNVs and their functional predictions." Hum Mutat. 2020;41(6):1123-1130.
Kessler MD, Loesch DP, Perry JA, et al. "De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population." Proc Natl Acad Sci U S A. 2020;117(5):2560-2569.
Gigliotti JC, Tin A, Pourafshar S, et al. " Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans." J Am Soc Nephrol. 2020;31(1):102-116.
Johnson EL, Krauss GL, Kucharska-Newton AMaria, et al. "Dementia in late-onset epilepsy: The Atherosclerosis Risk in Communities study." Neurology. 2020;95(24):e3248-e3256.
Ning X, Ding N, Ballew SH, et al. "Diabetes, its duration, and the long-term risk of abdominal aortic aneurysm: The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2020;313:137-143.
Dighe S, Zhao J, Steffen L, et al. "Diet patterns and the incidence of age-related macular degeneration in the Atherosclerosis Risk in Communities (ARIC) study." Br J Ophthalmol. 2020;104(8):1070-1076.
Xu Z, Steffen LM, Selvin E. "Diet quality, change in diet quality and risk of incident CVD and diabetes." Public Health Nutr. 2020;23(2):329-338.
Surendran P, Feofanova EV, Lahrouchi N, et al. "Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals." Nat Genet. 2020;52(12):1314-1332.
Kim J, Wang W, Zhang M, et al. "Diurnal circadian variations in paroxysmal atrial fibrillation: The atherosclerosis risk in communities (ARIC) study." J Electrocardiol. 2020;63:98-103.
Howell SJ, German D, Bender A, et al. "Does Sex Modify an Association of Electrophysiological Substrate with Sudden Cardiac Death? The Atherosclerosis Risk in Communities (ARIC) Study." Cardiovasc Digit Health J. 2020;1(2):80-88.
Li X, Li Z, Zhou H, et al. "Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale." Nat Genet. 2020;52(9):969-983.
Alonso A, Chen LYee, Rudser KD, Norby FL, Rooney MR. "Effect of Magnesium Supplementation on Circulating Biomarkers of Cardiovascular Disease." Nutrients. 2020;12(6).
Cowan LT, Lakshminarayan K, Lutsey PL, Beck J, Offenbacher S. "Endodontic therapy and incident cardiovascular disease: The Atherosclerosis Risk in Communities (ARIC) study." J Public Health Dent. 2020;80(1):79-91.
Bressler J, Marioni RE, Walker RM, et al. "Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2020;75(3):473-480.
Longchamps RJ, Castellani CA, Yang SY, et al. "Evaluation of mitochondrial DNA copy number estimation techniques." PLoS One. 2020;15(1):e0228166.
Faulkner KM, Dickson VVaughan, Fletcher J, et al. "Factors Associated With Cognitive Impairment in Heart Failure With Preserved Ejection Fraction." J Cardiovasc Nurs. 2020.
Ding N, Yang C, Ballew SH, et al. "Fibrosis and Inflammatory Markers and Long-Term Risk of Peripheral Artery Disease: The ARIC Study." Arterioscler Thromb Vasc Biol. 2020;40(9):2322-2331.
Fuentes Lde Las, Sung YJu, Noordam R, et al. "Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci." Mol Psychiatry. 2020.
Lin D-Y, Zeng D, Couper D. "A general framework for integrative analysis of incomplete multiomics data." Genet Epidemiol. 2020;44(7):646-664.
Grasby KL, Jahanshad N, Painter JN, et al. "The genetic architecture of the human cerebral cortex." Science. 2020;367(6484).
Hofer E, Roshchupkin GV, Adams HHH, et al. "Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
Weng L-C, Hall AWeber, Choi SHoan, et al. "Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation." Circ Genom Precis Med. 2020;13(5):387-395.
Hahn J, Fu Y-P, Brown MR, et al. "Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium." PLoS One. 2020;15(11):e0230035.
Shah S, Henry A, Roselli C, et al. "Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure." Nat Commun. 2020;11(1):163.
Qian H, Kowalski MH, Kramer HJ, et al. "Genome-Wide Association of Kidney Traits in Hispanics/Latinos Using Dense Imputed Whole-Genome Sequencing Data: The Hispanic Community Health Study/Study of Latinos." Circ Genom Precis Med. 2020;13(4):e002891.
Feofanova EV, Chen H, Dai Y, et al. "A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos." Am J Hum Genet. 2020;107(5):849-863.
Keene KL, Hyacinth HI, Bis JC, et al. "Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke." Stroke. 2020;51(8):2454-2463.
Jian X, Sofer T, Tarraf W, et al. "Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos." Transl Psychiatry. 2020;10(1):245.
Shin J, Ma S, Hofer E, et al. "Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes." Cereb Cortex. 2020;30(7):4121-4139.
Rooney MR, Tang O, Pankow JS. "Glycaemic markers and all-cause mortality in older adults with and without diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2020.
Croll PH, Vernooij MW, Reid RI, et al. "Hearing loss and microstructural integrity of the brain in a dementia-free older population." Alzheimers Dement. 2020;16(11):1515-1523.
Folsom AR, Wang W, Parikh R, Lutsey PL, Beckman JD. "Hematocrit and incidence of venous thromboembolism." Res Pract Thromb Haemost. 2020;4(3):422-428.
Tang O, Matsushita K, Coresh JJ, et al. "High-Sensitivity Cardiac Troponin I and T for Cardiovascular Risk Stratification in Adults With Diabetes." Diabetes Care. 2020;43(10):e144-e146.
Tang O, Matsushita K, Coresh JJ, et al. "High-Sensitivity Cardiac Troponin I for Risk Stratification in Older Adults." J Am Geriatr Soc. 2020.
Quispe R, Michos ED, Martin SS, et al. "High-Sensitivity C-Reactive Protein Discordance With Atherogenic Lipid Measures and Incidence of Atherosclerotic Cardiovascular Disease in Primary Prevention: The ARIC Study." J Am Heart Assoc. 2020;9(3):e013600.
Ishigami J, Cowan LT, Demmer RT, Grams ME, Lutsey PL, Coresh JJ. "Hospitalization With Major Infection and Incidence of End-Stage Renal Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Mayo Clin Proc. 2020;95(9):1928-1939.
Fujiyoshi A, Suri FMK, Alonso A, et al. "Hyperglycemia, duration of diabetes, and intracranial atherosclerotic stenosis by magnetic resonance angiography: The ARIC-NCS study." J Diabetes Complications. 2020;34(9):107605.
Fanola CL, Norby FL, Shah AM, et al. "Incident Heart Failure and Long-Term Risk for Venous Thromboembolism." J Am Coll Cardiol. 2020;75(2):148-158.
Ishigami J, Cowan LT, Demmer RT, et al. "Incident Hospitalization with Major Cardiovascular Diseases and Subsequent Risk of ESKD: Implications for Cardiorenal Syndrome." J Am Soc Nephrol. 2020;31(2):405-414.
Bick AG, Popadin K, Thorball CW, et al. "Increased CHIP Prevalence Amongst People Living with HIV." medRxiv. 2020.
Bick AG, Weinstock JS, Nandakumar SK, et al. "Inherited causes of clonal haematopoiesis in 97,691 whole genomes." Nature. 2020;586(7831):763-768.
Poon AK, Whitsel EA, Heiss G, Soliman EZ, Wagenknecht LE, Suzuki T. "Insulin resistance and reduced cardiac autonomic function in older adults: the Atherosclerosis Risk in Communities study." BMC Cardiovasc Disord. 2020;20(1):217.
Johnson EL, Krauss GL, Walker KA, et al. "Late-onset epilepsy and 25-year cognitive change: The Atherosclerosis Risk in Communities (ARIC) study." Epilepsia. 2020;61(8):1764-1773.
Kats D, Evenson KR, Zeng D, Avery CL, Palta P, Kritchevsky SB. "Leisure-time physical activity volume, intensity, and duration from mid- to late-life in U.S. subpopulations by race and sex. The Atherosclerosis Risk In Communities (ARIC) Study." Aging (Albany NY). 2020;12(5):4592-4602.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
Aguilar D, Sun C, Hoogeveen RC, et al. "Levels and Change in Galectin-3 and Association With Cardiovascular Events: The ARIC Study." J Am Heart Assoc. 2020;9(13):e015405.
George KM, Lutsey PL, Kucharska-Newton AMaria, Palta P, Heiss G, Osypuk T. "Life-Course Individual and Neighborhood Socioeconomic Status and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." Am J Epidemiol. 2020;189(10):1134-1142.
Evans CR, Hong C-P, Folsom AR, et al. "Lifestyle Moderates Genetic Risk of Venous Thromboembolism: The ARIC Study." Arterioscler Thromb Vasc Biol. 2020;40(11):2756-2763.
Mehta A, Virani SS, Ayers CR, et al. "Lipoprotein(a) and Family History Predict Cardiovascular Disease Risk." J Am Coll Cardiol. 2020;76(7):781-793.
Ruban A, Daya N, Schneider ALC, et al. "Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." J Stroke. 2020;22(3):357-368.
Lamichhane AP, Couper DJ, Jenkins GP. "Longitudinal Associations Between Body Mass Index During Young Adulthood, Subsequent Weight Change, and Incident Diabetes During Mid- and Older-Adulthood in Non-Hispanic White and African American Populations: The Atherosclerosis Risk in Communities Study." Metab Syndr Relat Disord. 2020;18(7):313-320.
Lutsey PL, B Windham G, Misialek JR, Cushman M, Kucharska-Newton AMaria, Basu S. "Long-Term Association of Venous Thromboembolism With Frailty, Physical Functioning, and Quality of Life: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2020;9(12):e015656.
Alam AB, Lutsey PL, Gottesman RF, Tin A, Alonso A. "Low Serum Magnesium is Associated with Incident Dementia in the ARIC-NCS Cohort." Nutrients. 2020;12(10).
Oelsner EC, Balte PP, Bhatt SP, et al. "Lung function decline in former smokers and low-intensity current smokers: a secondary data analysis of the NHLBI Pooled Cohorts Study." Lancet Respir Med. 2020;8(1):34-44.
Bae SSharon, L Chang C, Merkin S S, Elashoff D, Ishigami J, Matsushita K. "Major Lipids and Future Risk of Pneumonia: 20-Year Observation of the Atherosclerosis Risk in Communities (ARIC) Study Cohort." Am J Med. 2020.
Maners J, Gill D, Pankratz N, et al. "A Mendelian randomization of γ' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke." Blood. 2020;136(26):3062-3069.
Maners J, Gill D, Pankratz N, et al. "A Mendelian randomization of γ' and total fibrinogen levels on venous thromboembolism and ischemic stroke." Blood. 2020.
Justice AE, Chittoor G, Gondalia R, et al. "Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems." Epigenomics. 2020;12(17):1483-1499.
Koton S, Schneider ALC, B Windham G, Mosley TH, Gottesman RF. "Microvascular Brain Disease Progression and Risk of Stroke: The ARIC Study." Stroke. 2020;51(11):3264-3270.
Palta P, Heiss G, Sharrett ARichey, et al. "Mid- and Late-Life Leisure-Time Physical Activity and Global Brain Amyloid Burden: The Atherosclerosis Risk in Communities (ARIC)-PET Study." J Alzheimers Dis. 2020;76(1):139-147.
Teramoto K, Junior WNadruz, Matsushita K, et al. "Mid- to Late-Life Time-Averaged Cumulative Blood Pressure and Late-Life Cardiac Structure, Function, and Heart Failure." Hypertension. 2020;76(3):808-818.
George KM, Folsom AR, Sharrett ARichey, Mosley TH, Gottesman RF, Hamedani AG. "Migraine Headache and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." Headache. 2020;60(5):946-953.
DeBarmore B, Longchamps RJ, Zhang Y, et al. "Mitochondrial DNA copy number and diabetes: the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open Diabetes Res Care. 2020;8(1).
Zhao D, Bartz TM, Sotoodehnia N, et al. "Mitochondrial DNA copy number and incident atrial fibrillation." BMC Med. 2020;18(1):246.
Hong YSoo, Longchamps RJ, Zhao D, et al. "Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2020;141(22):1823-1825.
Castellani CA, Longchamps RJ, Sumpter JA, et al. "Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs." Genome Med. 2020;12(1):84.
Murthy VL, Yu B, Wang W, et al. "Molecular Signature of Multisystem Cardiometabolic Stress and Its Association With Prognosis." JAMA Cardiol. 2020.
Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Ntalla I, Weng L-C, Cartwright JH, et al. "Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction." Nat Commun. 2020;11(1):2542.
Baldassari AR, Sitlani CM, Highland HM, et al. "Multi-Ethnic Genome-Wide Association Study of Decomposed Cardioelectric Phenotypes Illustrates Strategies to Identify and Characterize Evidence of Shared Genetic Effects for Complex Traits." Circ Genom Precis Med. 2020;13(4):e002680.
Love S-AM, North KE, Zeng D, et al. "Nine-Year Ethanol Intake Trajectories and Their Association With 15-Year Cognitive Decline Among Black and White Adults." Am J Epidemiol. 2020;189(8):788-800.
George KM, Folsom AR, Norby FL. "No Association Found Between Midlife Seropositivity for Infection and Subsequent Cognitive Decline: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Geriatr Psychiatry Neurol. 2020;33(1):15-21.

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