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ARIC Publications

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Teumer A, Chaker L, Groeneweg S, et al. "Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.
Crosby J, Peloso GM, Auer PL, et al. "Loss-of-function mutations in APOC3, triglycerides, and coronary disease." N Engl J Med. 2014;371(1):22-31.
Thibord F, Song C, Pattee J, et al. FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer.. Vol. 19.; 2021. J Thromb Haemost 19(8).
Thorgeirsson TE, Gudbjartsson DF, Sulem P, et al. "A common biological basis of obesity and nicotine addiction." Transl Psychiatry. 2013;3:e308.
Thorvaldsen T, Claggett BL, Shah A, et al. "Predicting Risk in Patients Hospitalized for Acute Decompensated Heart Failure and Preserved Ejection Fraction: The Atherosclerosis Risk in Communities Study Heart Failure Community Surveillance." Circ Heart Fail. 2017;10(12).
Thyagarajan B, Brott M, Mink P, et al. "CYP1B1 and CYP19 gene polymorphisms and breast cancer incidence: no association in the ARIC study." Cancer Lett. 2004;207(2):183-9.
Tikellis G, Anuradha S, Klein R, Wong T Y. "Association between physical activity and retinal microvascular signs: the Atherosclerosis Risk in Communities (ARIC) Study." Microcirculation. 2010;17(5):381-93.
Tikellis G, Arnett DK, Skelton TN, et al. "Retinal arteriolar narrowing and left ventricular hypertrophy in African Americans. the Atherosclerosis Risk in Communities (ARIC) study." Am J Hypertens. 2008;21(3):352-9.
Tilling K, Smith G D, Chambless L, et al. "The relation between birth weight and intima-media thickness in middle-aged adults." Epidemiology. 2004;15(5):557-64.
Tilling K, Sterne JAC, Szklo M. "Estimating the effect of cardiovascular risk factors on all-cause mortality and incidence of coronary heart disease using G-estimation: the atherosclerosis risk in communities study." Am J Epidemiol. 2002;155(8):710-8.
Tilling K, Lawlor DA, Smith GDavey, Chambless L, Szklo M. "The relation between components of adult height and intimal-medial thickness in middle age: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2006;164(2):136-42.
Tin A, Li Y, Brody JA, et al. "Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels." Nat Commun. 2018;9(1):4228.
Tin A, Grams ME, Maruthur NM, et al. "Results from the Atherosclerosis Risk in Communities study suggest that low serum magnesium is associated with incident kidney disease." Kidney Int. 2015;87(4):820-7.
Tin A, Yu B, Ma J, et al. "Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay." J Appl Lab Med. 2019;4(1):30-39.
Tin A, Köttgen A, Folsom AR, et al. "Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study." BMC Genet. 2015;16:56.
Tin A, Marten J, Kuhns VLHalperin, et al. "Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels." Nat Genet. 2019;51(10):1459-1474.
Tin A, Astor BC, Boerwinkle E, Hoogeveen RC, Coresh J, Kao W H L. "Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin." Hum Genet. 2013;132(6):619-27.
Tin A, Grams ME, Ashar FN, et al. "Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study." J Am Soc Nephrol. 2016;27(8):2467-73.
Tin A, Balakrishnan P, Beaty TH, Boerwinkle E, Hoogeveen RC, Young JH. "GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2016;33(7):968-75.
Tin A, Scharpf R, Estrella MM, et al. "The Loss of Associates with Kidney Failure and Heart Failure." J Am Soc Nephrol. 2017;28(11):3345-3352.
Tin A, Grams ME, Maruthur NM, et al. "Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(5):784-90.
Tin A, Astor BC, Boerwinkle E, Hoogeveen RC, Coresh J, Kao LWH. "Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans." Nephrol Dial Transplant. 2013;28(6):1497-504.
Tin A, Bressler J, Simino J, et al. "Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study." Neurology. 2022.
Tin A, Walker KA, Bressler J, et al. "Association between Circulating Protein C Levels and Incident Dementia: The Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2021;55(4):306-315.
Tin A, Colantuoni E, Boerwinkle E, et al. "Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate." J Hum Genet. 2013;58(7):461-6.
Tin A, Woodward OM, Kao W H L, et al. "Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele." Hum Mol Genet. 2011;20(20):4056-68.
Ting J, Jiang K, Du S, et al. "Longitudinal Blood Pressure Patterns from Mid-to-Late Life and Late-life Hearing Loss in the Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2021.
Tommerdahl KL, Hu EA, Selvin E, et al. "Coffee Consumption May Mitigate the Risk for Acute Kidney Injury: Results From the Atherosclerosis Risk in Communities Study." Kidney Int Rep. 2022;7(7):1665-1672.
Toole JF, Lefkowitz DS, Chambless LE, Wijnberg L, Paton CC, Heiss G. "Self-reported transient ischemic attack and stroke symptoms: methods and baseline prevalence. The ARIC Study, 1987-1989." Am J Epidemiol. 1996;144(9):849-56.
Toole JF, Chambless LE, Heiss G, Tyroler HA, Paton CC. "Prevalence of stroke and transient ischemic attacks in the Atherosclerosis Risk in Communities (ARIC) study." Ann Epidemiol. 1993;3(5):500-3.
Tragante V, Barnes MR, Ganesh SK, et al. "Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci." Am J Hum Genet. 2014;94(3):349-60.
Travis RC, Perez-Cornago A, Appleby PN, et al. "A Collaborative Analysis of Individual Participant Data from 19 Prospective Studies Assesses Circulating Vitamin D and Prostate Cancer Risk." Cancer Res. 2019;79(1):274-285.
Traylor M, Malik R, Nalls MA, et al. "Genetic variation at 16q24.2 is associated with small vessel stroke." Ann Neurol. 2017;81(3):383-394.
Traylor M, Farrall M, Holliday EG, et al. "Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies." Lancet Neurol. 2012;11(11):951-62.
Truesdale KP, Stevens J, Cai J. "Effect of 3-year weight history on blood pressure: the atherosclerosis risk in communities study." Obesity (Silver Spring). 2008;16(5):1112-9.
Truesdale KP, Stevens J, Cai J. "Nine-year changes in cardiovascular disease risk factors with weight maintenance in the atherosclerosis risk in communities cohort." Am J Epidemiol. 2007;165(8):890-900.
Truesdale KP, Stevens J, Cai J. "The effect of weight history on glucose and lipids: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2005;161(12):1133-43.
Tsai AW, Cushman M, Rosamond WD, et al. "Coagulation factors, inflammation markers, and venous thromboembolism: the longitudinal investigation of thromboembolism etiology (LITE)." Am J Med. 2002;113(8):636-42.
Tsai AW, Folsom AR, Rosamond WD, Jones DW. "Ankle-brachial index and 7-year ischemic stroke incidence: the ARIC study." Stroke. 2001;32(8):1721-4.
Tsai AW, Cushman M, Tsai MY, et al. "Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2003;72(3):192-200.
Tsai AW, Cushman M, Rosamond WD, Heckbert SR, Polak JF, Folsom AR. "Cardiovascular risk factors and venous thromboembolism incidence: the longitudinal investigation of thromboembolism etiology." Arch Intern Med. 2002;162(10):1182-9.
Tung S, Kendrick J, Surapaneni A, et al. "Association Between Acute Kidney Injury and Dementia in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2022.
Turcot V, Lu Y, Highland HM, et al. "Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity." Nat Genet. 2019;51(7):1191-1192.
Turcot V, Lu Y, Highland HM, et al. "Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity." Nat Genet. 2018;50(1):26-41.
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Vaidean GD, Rautaharju PM, Prineas RJ, et al. "The association of spatial T wave axis deviation with incident coronary events. The ARIC cohort." BMC Cardiovasc Disord. 2005;5(1):2.
Vaidean GD, Schroeder EB, Whitsel EA, et al. "Short-term repeatability of electrocardiographic spatial T-wave axis and QT interval." J Electrocardiol. 2005;38(2):139-47.
van Capelleveen JC, Bochem AE, S Boekholdt M, et al. "Association of High-Density Lipoprotein-Cholesterol Versus Apolipoprotein A-I With Risk of Coronary Heart Disease: The European Prospective Investigation Into Cancer-Norfolk Prospective Population Study, the Atherosclerosis Risk in Communities Study, and ." J Am Heart Assoc. 2017;6(8).
van den Berg ME, Warren HR, Cabrera CP, et al. "Discovery of novel heart rate-associated loci using the Exome Chip." Hum Mol Genet. 2017;26(12):2346-2363.
van der Laan SW, Fall T, Soumaré A, et al. "Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study." J Am Coll Cardiol. 2016;68(9):934-45.
van der Lee SJ, Holstege H, Wong THang, et al. "PLD3 variants in population studies." Nature. 2015;520(7545):E2-3.
van der Velde M, Matsushita K, Coresh J, et al. "Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts." Kidney Int. 2011;79(12):1341-52.
van Leeuwen EM, Sabo A, Bis JC, et al. "Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels." J Med Genet. 2016;53(7):441-9.
van Loon J, Dehghan A, Weihong T, et al. "Genome-wide association studies identify genetic loci for low von Willebrand factor levels." Eur J Hum Genet. 2016;24(7):1035-40.
van Setten J, Brody JA, Jamshidi Y, et al. "PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity." Nat Commun. 2018;9(1):2904.
van Setten J, Verweij N, Mbarek H, et al. "Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits." Eur J Hum Genet. 2019;27(6):952-962.
Vardarajan BN, Barral S, Jaworski J, et al. "Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease." Ann Clin Transl Neurol. 2018;5(4):406-417.
Vardeny O, Gupta DK, Claggett B, et al. "Insulin resistance and incident heart failure the ARIC study (Atherosclerosis Risk in Communities)." JACC Heart Fail. 2013;1(6):531-6.
Vart P, Coresh JJ, Kwak L, Ballew SH, Heiss G. "Socioeconomic Status and Incidence of Hospitalization With Lower-Extremity Peripheral Artery Disease: Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2017;6(8).
Vart P, Grams ME, Ballew SH, Woodward M, Coresh JJ. "Socioeconomic status and risk of kidney dysfunction: the Atherosclerosis Risk in Communities study." Nephrol Dial Transplant. 2019;34(8):1361-1368.
Vasan RS, Musani SK, Matsushita K, et al. "Epidemiology of Heart Failure Stages in Middle-Aged Black People in the Community: Prevalence and Prognosis in the Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2021;10(9):e016524.
Verhaaren BFJ, Debette S, Bis JC, et al. "Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI." Circ Cardiovasc Genet. 2015;8(2):398-409.
Verweij N, Mateo Leach I, Isaacs A, et al. "Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram." Hum Mol Genet. 2016;25(10):2093-2103.
Vigo A, Duncan BB, Schmidt MI, et al. "Glutamic acid decarboxylase antibodies are indicators of the course, but not of the onset, of diabetes in middle-aged adults: the Atherosclerosis Risk in Communities Study." Braz J Med Biol Res. 2007;40(7):933-41.
Virani SS, Nambi V, Hoogeveen R, et al. "Relationship between circulating levels of RANTES (regulated on activation, normal T-cell expressed, and secreted) and carotid plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study." Eur Heart J. 2011;32(4):459-68.
Virani SS, Brautbar A, Davis BC, et al. "Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2012;125(2):241-9.
Virani SS, Catellier DJ, Pompeii LA, et al. "Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study." Atherosclerosis. 2011;219(2):596-602.
Vishnu A, Gurka MJ. "The severity of the metabolic syndrome increases over time within individuals, independent of baseline metabolic syndrome status and medication use: The Atherosclerosis Risk in Communities Study." Atherosclerosis. 2015;243(1):278-85.
Vitelli LL, Shahar E, Heiss G, et al. "Glycosylated hemoglobin level and carotid intimal-medial thickening in nondiabetic individuals. The Atherosclerosis Risk in Communities Study." Diabetes Care. 1997;20(9):1454-8.
Vitelli LL, Crow RS, Shahar E, Hutchinson RG, Rautaharju PM, Folsom AR. "Electrocardiographic findings in a healthy biracial population. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Am J Cardiol. 1998;81(4):453-9.
Voight BF, Peloso GM, Orho-Melander M, et al. "Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study." Lancet. 2012;380(9841):572-80.
Voight BF, Scott LJ, Steinthorsdottir V, et al. "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis." Nat Genet. 2010;42(7):579-89.
Vojinovic D, Adams HH, Jian X, et al. "Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume." Nat Commun. 2018;9(1):3945.
Volcik KA, Barkley R A, Hutchinson RG, et al. "Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants." Am J Epidemiol. 2006;164(4):342-8.
Volcik KA, Ballantyne CM, Hoogeveen R, Folsom AR, Boerwinkle E. "Intercellular adhesion molecule-1 G241R polymorphism predicts risk of incident ischemic stroke: Atherosclerosis Risk in Communities study." Stroke. 2010;41(5):1038-40.
Volcik K, Ballantyne CM, Pownall HJ, A Sharrett R, Boerwinkle E. "Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study." J Stud Alcohol Drugs. 2007;68(4):485-92.
Volcik KA, Catellier D, Folsom AR, Matijevic N, Wasserman B, Boerwinkle E. "SELP and SELPLG genetic variation is associated with cell surface measures of SELP and SELPLG: the Atherosclerosis Risk in Communities Carotid MRI Study." Clin Chem. 2009;55(6):1076-82.
Volcik KA, Nettleton JA, Ballantyne CM, Boerwinkle E. "Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2008;87(6):1926-31.
Volcik KA, Ballantyne CM, Coresh J, Folsom AR, Boerwinkle E. "Specific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2007;195(1):e76-82.
Volcik KA, Ballantyne CM, Braun MC, Coresh J, Mosley TH, Boerwinkle E. "Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study." Am J Hypertens. 2008;21(5):533-8.
Volcik KA, Ballantyne CM, Coresh J, Folsom AR, Wu KK, Boerwinkle E. "P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study." Atherosclerosis. 2006;186(1):74-9.

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