ARIC Publications
Associations of lower-limb atherosclerosis and arteriosclerosis with cardiovascular risk factors and disease in older adults: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;340:53-60.
"The aortic-femoral arterial stiffness gradient is blood pressure independent in older adults: the atherosclerosis risk in communities (ARIC) study." J Hypertens. 2021.
"Associations between carotid-femoral and heart-femoral pulse wave velocity in older adults: the Atherosclerosis Risk In Communities study." J Hypertens. 2020;38(9):1786-1793.
"Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort." Stroke. 2008;39(8):2268-73.
"Apolipoprotein E genotype and incident ischemic stroke: the Atherosclerosis Risk in Communities Study." Stroke. 2005;36(11):2484-6.
"Risk factors for intracerebral hemorrhage in a pooled prospective study." Stroke. 2007;38(10):2718-25.
"Medication Adherence Based on Part D Claims for Patients With Heart Failure After Hospitalization (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2015;116(3):413-9.
"Imaging-based indices of Neuropathology and gait speed decline in older adults: the atherosclerosis risk in communities study." Brain Imaging Behav. 2021.
"Association of Midlife Plasma Amyloid-β Levels With Cognitive Impairment in Late Life: The ARIC Neurocognitive Study." Neurology. 2021;97(11):e1123-e1131.
"Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2017;70(5):675-685.
"A prospective study of serum metabolites and risk of ischemic stroke." Neurology. 2019;92(16):e1890-e1898.
"Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease." Hypertension. 2021;78(5):1555-1566.
"Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits." HGG Adv. 2021;2(1).
"A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure." Am J Hum Genet. 2018;102(3):375-400.
"An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group." Genet Epidemiol. 2016;40(5):404-15.
"An empirical comparison of meta-analysis and mega-analysis of individual participant data for identifying gene-environment interactions." Genet Epidemiol. 2014;38(4):369-78.
"A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure." Hum Mol Genet. 2019;28(15):2615-2633.
" Risk Alleles, Cardiac Markers, and Risk of ESKD in African Americans: The Atherosclerosis Risk in Communities Study." Kidney Med. 2020;2(4):502-504.
"Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals." Nat Genet. 2020;52(12):1314-1332.
"Effect of apolipoprotein E polymorphism on fasting retinyl palmitate level." Biochem Mol Med. 1995;55(2):156-7.
"Apolipoprotein E genotype and lipid transport: insight into the role of the epsilon 4 allele." Atherosclerosis. 1994;106(1):119-21.
"Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia." Arterioscler Thromb Vasc Biol. 1996;16(8):941-7.
"Prevalence of Intracranial Atherosclerotic Stenosis Using High-Resolution Magnetic Resonance Angiography in the General Population: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(5):1187-93.
"Cognitive impairment and intracranial atherosclerotic stenosis in general population." Neurology. 2018;90(14):e1240-e1247.
"Novel hemostatic factor levels and risk of ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study." Cerebrovasc Dis. 2010;29(5):497-502.
"Carotid Intima-Media Thickness and the Risk of Sudden Cardiac Death: The ARIC Study and the CHS." J Am Heart Assoc. 2020;9(19):e016981.
"Kidney function and sudden cardiac death in the community: The Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2016;180:46-53.
"HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials." Lancet. 2015;385(9965):351-61.
"Epigenetic Loci of Blood Pressure." Circ Genom Precis Med. 2019;12(1):e002341.
"Estrogen replacement therapy and cognitive functioning in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1996;144(11):1048-57.
"Trends in plasma cholesterol levels in the atherosclerosis risk in communities (ARIC) study." Prev Med. 2000;30(3):252-9.
"Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.
"Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases." Am J Hum Genet. 2016;99(1):22-39.
" "Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program." Nature. 2021;590(7845):290-299.
"Blood viscosity and hematocrit as risk factors for type 2 diabetes mellitus: the atherosclerosis risk in communities (ARIC) study." Am J Epidemiol. 2008;168(10):1153-60.
"Association of serum uric acid with incident atrial fibrillation (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2011;108(9):1272-6.
"Hemodynamic Correlates of Blood Pressure in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." J Clin Hypertens (Greenwich). 2016;18(12):1222-1227.
"Habitual physical activity and central artery stiffening in older adults: the Atherosclerosis Risk in Communities study." J Hypertens. 2018;36(9):1889-1894.
"The metabolic syndrome is associated with reduced risk of prostate cancer." Am J Epidemiol. 2006;164(11):1094-102.
"African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans." Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005.
"High-Sensitivity Cardiac Troponin I and T for Cardiovascular Risk Stratification in Adults With Diabetes." Diabetes Care. 2020;43(10):e144-e146.
"Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG." Eur J Vasc Endovasc Surg. 2020;59(1):92-97.
"Association of SERPINA9 gene variants with carotid artery atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study." Int J Mol Epidemiol Genet. 2013;4(4):258-67.
"Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease." Am J Hum Genet. 2012;91(1):152-62.
"Performance of High-Sensitivity Cardiac Troponin Assays to Reflect Comorbidity Burden and Improve Mortality Risk Stratification in Older Adults With Diabetes." Diabetes Care. 2020;43(6):1200-1208.
"Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study." Blood. 2010;116(23):5032-6.
"Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function." PLoS One. 2014;9(7):e100776.
"Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
"The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study." Angiology. 2019;70(2):130-140.
"High-Sensitivity Cardiac Troponin I for Risk Stratification in Older Adults." J Am Geriatr Soc. 2020.
"Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans." Am J Hematol. 2015;90(6):534-40.
"A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium." Genet Epidemiol. 2013;37(5):512-521.
"Burden of rare exome sequence variants in PROC gene is associated with venous thromboembolism: a population-based study." J Thromb Haemost. 2020;18(2):445-453.
"Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
"Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis." JAMA. 2016;315(2):164-74.
"Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling." J Am Stat Assoc. 2015;110(510):560-572.
"A large-scale transcriptome-wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine-mapping." Genet Epidemiol. 2022;46(1):3-16.
"Metabolomics of Dietary Acid Load and Incident Chronic Kidney Disease." J Ren Nutr. 2021.
"Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed." Cell Genom. 2022;2(1).
"Relation of aortic valve sclerosis to risk of coronary heart disease in African-Americans." Am J Cardiol. 2005;95(3):401-4.
"Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study." BMC Genet. 2013;14:33.
"Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2007;99(10):1413-20.
"Dietary fat intake and carotid artery wall thickness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1994;139(10):979-89.
"Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study." JAMA Oncol. 2017;3(5):636-651.
"Evolution and functional impact of rare coding variation from deep sequencing of human exomes." Science. 2012;337(6090):64-9.
"Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis." PLoS Med. 2020;17(10):e1003361.
"Mid- to Late-Life Time-Averaged Cumulative Blood Pressure and Late-Life Cardiac Structure, Function, and Heart Failure." Hypertension. 2020;76(3):808-818.
"Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)." J Am Heart Assoc. 2018;7(8).
"Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study." J Am Heart Assoc. 2014;3(6):e001387.
"Evaluation of magnetic resonance imaging for quantification of intraabdominal fat in human beings by spin-echo and inversion-recovery protocols." Am J Clin Nutr. 1995;62(2):297-301.
"Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
"Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes." Diabetes. 2016;65(3):803-17.
"Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.
"Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria." Nat Commun. 2019;10(1):4130.
"Loss-of-function mutations in APOC3, triglycerides, and coronary disease." N Engl J Med. 2014;371(1):22-31.
"FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer.. Vol. 19.; 2021. J Thromb Haemost 19(8).
Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke." J Am Heart Assoc. 2022;11(15):e025703.
"A common biological basis of obesity and nicotine addiction." Transl Psychiatry. 2013;3:e308.
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