ARIC Publications
"Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases." J Am Soc Nephrol. 2021.
"Population sequencing data reveal a compendium of mutational processes in the human germ line." Science. 2021;373(6558):1030-1035.
"Pre-Statistical Considerations for Harmonization of Cognitive Instruments: Harmonization of ARIC, CARDIA, CHS, FHS, MESA, and NOMAS." J Alzheimers Dis. 2021.
"Prestroke Physical Activity and Adverse Health Outcomes After Stroke in the Atherosclerosis Risk in Communities Study." Stroke. 2021:STROKEAHA120032695.
"Prevalence of Disability Associated With Head Injury With Loss of Consciousness in Adults in the United States: A Population-Based Study." Neurology. 2021;97(2):e124-e135.
"Prevalence of peripheral neuropathy defined by monofilament insensitivity in middle-aged and older adults in two US cohorts." Sci Rep. 2021;11(1):19159.
"Prognostic value of shock index in patients admitted with non-ST-segment elevation myocardial infarction: the ARIC study community surveillance." Eur Heart J Acute Cardiovasc Care. 2021.
"Proof of Concept Example for Use of Simulation to Allow Data Pooling Despite Privacy Restrictions." Epidemiology. 2021;32(5):638-647.
"Prospective Analysis of Leisure-Time Physical Activity in Midlife and Beyond and Brain Damage on MRI in Older Adults." Neurology. 2021;96(7):e964-e974.
"Prostate Cancer Mortality Associated with Aggregate Polymorphisms in Androgen-Regulating Genes: The Atherosclerosis Risk in the Communities (ARIC) Study." Cancers (Basel). 2021;13(8).
"Proteins Associated with Risk of Kidney Function Decline in the General Population." J Am Soc Nephrol. 2021;32(9):2291-2302.
"Proteomics and Risk of Atrial Fibrillation in Older Adults (From the Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2021;161:42-50.
"Proton Pump Inhibitor Use, Hypomagnesemia and Risk of Cardiovascular Diseases: The Atherosclerosis Risk in Communities (ARIC) Study." J Clin Gastroenterol. 2021;55(8):677-683.
"Psychosocial factors and subsequent risk of hospitalizations with peripheral artery disease: The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2021;329:36-43.
"Racial Differences and Temporal Obesity Trends in Heart Failure with Preserved Ejection Fraction." J Am Geriatr Soc. 2021.
"Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis." Circ Genom Precis Med. 2021;14(4):e003300.
"Reflection on modern methods: shared-parameter models for longitudinal studies with missing data." Int J Epidemiol. 2021;50(4):1384-1393.
"Relationship Between Central Artery Stiffness, Brain Arterial Dilation, and White Matter Hyperintensities in Older Adults: The ARIC Study-Brief Report." Arterioscler Thromb Vasc Biol. 2021;41(6):2109-2116.
"The Relationship of ε4, Race, and Sex on the Age of Onset and Risk of Dementia." Front Neurol. 2021;12:735036.
"Remnant cholesterol predicts cardiovascular disease beyond LDL and ApoB: a primary prevention study." Eur Heart J. 2021.
"Resistance to antihypertensive treatment and long-term risk: The Atherosclerosis Risk in Communities study." J Clin Hypertens (Greenwich). 2021;23(10):1887-1896.
"Retinopathy and Risk of Kidney Disease in Persons With Diabetes." Kidney Med. 2021;3(5):808-815.e1.
"Risk of peripheral artery disease according to race and sex: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2021;324:52-57.
"Risk of Progression to Diabetes Among Older Adults With Prediabetes." JAMA Intern Med. 2021;181(4):511-519.
"Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries." Genetics. 2021;218(1).
"SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe." Eur Heart J. 2021;42(25):2439-2454.
"SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions." Eur Heart J. 2021;42(25):2455-2467.
"Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program." Nature. 2021;590(7845):290-299.
"Serum albumin and risks of hospitalization and death: Findings from the Atherosclerosis Risk in Communities study." J Am Geriatr Soc. 2021.
"Serum Metabolites Associated with Healthy Diets in African Americans and European Americans." J Nutr. 2021;151(1):40-49.
"Sex Differences in Cognitive Decline Among US Adults." JAMA Netw Open. 2021;4(2):e210169.
"Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability." Nat Commun. 2021;12(1):24.
"Six-year changes in N-terminal pro-brain natriuretic peptide and changes in weight and risk of obesity." Obesity (Silver Spring). 2021;29(7):1215-1222.
"Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2021;146:15-21.
"Sphingolipids and physical function in the Atherosclerosis Risk in Communities (ARIC) study." Sci Rep. 2021;11(1):1169.
"Subclinical Vascular Disease Burden and Premature Mortality Among Middle-aged Adults: the Atherosclerosis Risk in Communities Study." J Gen Intern Med. 2021.
"Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure." J Am Coll Cardiol. 2021;78(1):42-52.
"Symptomatic and asymptomatic peripheral artery disease and the risk of abdominal aortic aneurysm: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2021;333:32-38.
"A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program." Am J Epidemiol. 2021;190(10):1977-1992.
"A systematic review and participant-level meta-analysis found little association of retinal microvascular caliber with reduced kidney function." Kidney Int. 2021;99(3):696-706.
"Temporal Trends and Prognosis of Physical Examination Findings in Patients With Acute Decompensated Heart Failure: The ARIC Study Community Surveillance." Circ Heart Fail. 2021;14(12):e008403.
"The trans-ancestral genomic architecture of glycemic traits." Nat Genet. 2021;53(6):840-860.
"Trends, Management, and Outcomes of Acute Myocardial Infarction Hospitalizations With In-Hospital-Onset Versus Out-of-Hospital Onset: The ARIC Study." J Am Heart Assoc. 2021;10(2):e018414.
"Triglyceride-rich lipoproteins, apolipoprotein C-III, angiopoietin-like protein 3, and cardiovascular events in older adults: Atherosclerosis Risk in Communities (ARIC) study." Eur J Prev Cardiol. 2021.
"Two-Week Burden of Arrhythmias across CKD Severity in a Large Community-Based Cohort: The ARIC Study." J Am Soc Nephrol. 2021;32(3):629-638.
"Visual Function, Physical Function, and Activities of Daily Living in Two Aging Communities." Transl Vis Sci Technol. 2021;10(14):15.
"Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium." EBioMedicine. 2021;63:103157.
"Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative." Hum Mol Genet. 2021.
"Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program." Genome Med. 2021;13(1):136.
"Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program." Am J Hum Genet. 2021;108(6):1165.
"18-year change in serum intact fibroblast growth factor 23 from midlife to late life and risk of mortality: the ARIC Study." Eur J Endocrinol. 2022;187(1):39-47.
"Accuracy of self- and proxy-rated hearing among older adults with and without cognitive impairment." J Am Geriatr Soc. 2022;70(2):490-500.
"American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease." Circulation. 2022;145(11):808-818.
"Apolipoprotein E Polymorphism, Cardiac Remodeling, and Heart Failure in the ARIC Study." J Card Fail. 2022;28(7):1128-1136.
"Arterial stiffness and contralateral differences in blood pressure: The Atherosclerosis Risk in Communities (ARIC) study." J Clin Hypertens (Greenwich). 2022;24(7):878-884.
"Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data." Hum Mol Genet. 2022.
"Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data." Nat Genet. 2022;54(3):263-273.
"Association Between Acute Kidney Injury and Dementia in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2022.
"The Association Between Midlife Leisure-Time Physical Activity and Hearing Loss in Late-life in the Atherosclerosis Risk in Communities (ARIC) Study." J Gerontol A Biol Sci Med Sci. 2022.
"Association Between Ultraprocessed Food Consumption and Risk of Incident CKD: A Prospective Cohort Study." Am J Kidney Dis. 2022.
"Association of Brain Volumes and White Matter Injury With Race, Ethnicity, and Cardiovascular Risk Factors: The Multi-Ethnic Study of Atherosclerosis." J Am Heart Assoc. 2022;11(7):e023159.
"Association of Carotid Intima-Media Thickness with Brain MRI Markers in the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Stroke Cerebrovasc Dis. 2022;31(5):106388.
"Association of Cigarette Smoking Patterns Over 30 Years With Audiometric Hearing Impairment and Speech-in-Noise Perception: The Atherosclerosis Risk in Communities Study." JAMA Otolaryngol Head Neck Surg. 2022;148(3):243-251.
"Association of Echocardiographic Measures of Left Atrial Function and Size With Incident Dementia." JAMA. 2022;327(12):1138-1148.
"Association of Head Injury With Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Cohort." Neurology. 2022;98(8):e808-e817.
"Association of Ischemic Stroke Incidence, Severity, and Recurrence With Dementia in the Atherosclerosis Risk in Communities Cohort Study." JAMA Neurol. 2022;79(3):271-280.
"Association of Kidney Function Measures With Signs of Neurodegeneration and Small Vessel Disease on Brain Magnetic Resonance Imaging: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2022.
"Association of Left Atrial Structure and Function With Heart Failure in Older Adults." J Am Coll Cardiol. 2022;79(16):1549-1561.
"Association of Mild Valvular Lesions With Long-term Cardiovascular Outcomes Among Black Adults." JAMA Netw Open. 2022;5(5):e2211946.
"The association of motoric cognitive risk with incident dementia and neuroimaging characteristics: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2022;18(3):434-444.
"Association of Optical Coherence Tomography and Optical Coherence Tomography Angiography Retinal Features With Visual Function in Older Adults." JAMA Ophthalmol. 2022;140(8):809-817.
"Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality." JAMA Cardiol. 2022;7(7):723-732.
"Association of physical activity with the incidence of atrial fibrillation in persons > 65 years old: the Atherosclerosis Risk in Communities (ARIC) study." BMC Cardiovasc Disord. 2022;22(1):196.
"Association of Pulmonary Function With Late-Life Cardiac Function and Heart Failure Risk: The ARIC Study." J Am Heart Assoc. 2022;11(14):e023990.
"Associations Between Atrial Arrhythmias and Brain Amyloid Deposition: The ARIC-PET Study." J Alzheimers Dis. 2022;86(1):43-48.
"The Associations of Dietary Copper With Cognitive Outcomes." Am J Epidemiol. 2022;191(7):1202-1211.
"Associations of late-life sleep medication use with incident dementia in the Atherosclerosis Risk in Communities (ARIC) Study." J Gerontol A Biol Sci Med Sci. 2022.