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ARIC Publications

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2017
Pankow JS, Tang W, Pankratz N, et al. "Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2017;37(3):589-597.
Christophersen IE, Rienstra M, Roselli C, et al. "Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation." Nat Genet. 2017;49(6):946-952.
Sumida K, Kwak L, Grams ME, et al. "Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2017;70(5):675-685.
Bressler J, Yu B, Mosley TH, et al. "Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study." Transl Psychiatry. 2017;7(7):e1173.
Walker KA, Hoogeveen RC, Folsom AR, et al. "Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study." Neurology. 2017;89(22):2262-2270.
Petruski-Ivleva N, Kucharska-Newton AMaria, Palta P, et al. "Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study." Nutrients. 2017;9(10).
Kalbaugh CA, Kucharska-Newton AMaria, Wruck L, et al. "Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2017;6(5).
Morrison AC, Huang Z, Yu B, et al. "Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits." Am J Hum Genet. 2017;100(2):205-215.
Smith JW, O'Neal WT, M Shoemaker B, Chen LYee, Alonso A, S Whalen P. "PR-Interval Components and Atrial Fibrillation Risk (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(3):466-472.
Seidelmann SB, Vardeny O, Claggett B, et al. "An Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality." J Am Heart Assoc. 2017;6(4).
Chen Y, Sang Y, Ballew SH, et al. "Race, Serum Potassium, and Associations With ESRD and Mortality." Am J Kidney Dis. 2017;70(2):244-251.
Fernandes-Silva MM, Shah AM, Hegde S, et al. "Race-Related Differences in Left Ventricular Structural and Functional Remodeling in Response to Increased Afterload: The ARIC Study." JACC Heart Fail. 2017;5(3):157-165.
Naorungroj S, Slade GD, Divaris K, Heiss G, Offenbacher S. "Racial differences in periodontal disease and 10-year self-reported tooth loss among late middle-aged and older adults: the dental ARIC study." J Public Health Dent. 2017;77(4):372-382.
Qiao Y, Suri FK, Zhang Y, et al. "Racial Differences in Prevalence and Risk for Intracranial Atherosclerosis in a US Community-Based Population." JAMA Cardiol. 2017;2(12):1341-1348.
Nadruz W, Claggett B, Henglin M, et al. "Racial Disparities in Risks of Stroke." N Engl J Med. 2017;376(21):2089-2090.
Maheshwari A, Norby FL, Soliman EZ, et al. "Relation of Prolonged P-Wave Duration to Risk of Sudden Cardiac Death in the General Population (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(9):1302-1306.
Rapson IR, Michos ED, Alonso A, Hirsch AT, Matsushita K, Reis JP. "Serum 25-hydroxyvitamin D is associated with incident peripheral artery disease among white and black adults in the ARIC study cohort." Atherosclerosis. 2017;257:123-129.
Bello NA, Hyacinth HI, Roetker NS, et al. "Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function." Blood. 2017;129(6):799-801.
Liang J, Le TH, Edwards DRVelez, et al. "Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2017;13(5):e1006728.
Millen AE, Nie J, Sahli MW, et al. "Vitamin D Status and Prevalent Early Age-Related Macular Degeneration in African Americans and Caucasians: The Atherosclerosis Risk in Communities (ARIC) Study." J Nutr Health Aging. 2017;21(7):772-780.
Simino J, Wang Z, Bressler J, et al. "Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study." PLoS One. 2017;12(7):e0180046.
de Vries PS, Yu B, Feofanova EV, et al. "Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study." Hum Mol Genet. 2017;26(17):3442-3450.
2018
Charles BA, Hsieh MM, Adeyemo AA, et al. "Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia." PLoS One. 2018;13(3):e0194400.
Johnson EL, Krauss GL, Lee AK, et al. "Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." JAMA Neurol. 2018;75(11):1375-1382.
Lutsey PL, Norby FL, Alonso A, Cushman M, Chen LYee, Michos ED. "Atrial fibrillation and venous thromboembolism: evidence of bidirectionality in the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2018;16(4):670-679.
Caughey MC, Qiao Y, Windham BGwen, Gottesman RF, Mosley TH. "Carotid Intima-Media Thickness and Silent Brain Infarctions in a Biracial Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2018;31(8):869-875.
Wang X, Pan Y, Zhu H, et al. "An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression." Clin Epigenetics. 2018;10:3.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Li C, Grove ML, Yu B, Jones BC, Morrison A, Boerwinkle E. "Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population." Hum Genet. 2018;137(1):85-94.
Loomis SJ, Li M, Maruthur NM, et al. "Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study." Diabetes. 2018;67(8):1684-1696.
Keaton JM, Gao C, Guan M, et al. "Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans." Genet Epidemiol. 2018;42(6):559-570.
Chatterjee R, Davenport CA, Raffield LM, et al. "KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts." PLoS One. 2018;13(8):e0203213.
Mou L, Norby FL, Chen LYee, et al. "Lifetime Risk of Atrial Fibrillation by Race and Socioeconomic Status: ARIC Study (Atherosclerosis Risk in Communities)." Circ Arrhythm Electrophysiol. 2018;11(7):e006350.
Mondul AM, Joshu CE, Barber JR, et al. "Longer-term Lipid-lowering Drug Use and Risk of Incident and Fatal Prostate Cancer in Black and White Men in the ARIC Study." Cancer Prev Res (Phila). 2018;11(12):779-788.
Yano Y, Griswold M, Wang W, et al. "Long-Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study." J Am Heart Assoc. 2018;7(15):e009578.
West NA, Tingle JV, Simino J, Selvin E, Bressler J. "The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity." Alzheimer Dis Assoc Disord. 2018;32(2):131-136.
Roetker NS, Pankow JS, Bressler J, Morrison AC. "Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities)." Circ Genom Precis Med. 2018;11(3):e001937.
Feofanova EV, Yu B, Metcalf GA, et al. "Sequence-Based Analysis of Lipid-Related Metabolites in a Multiethnic Study." Genetics. 2018;209(2):607-616.
George KM, Selvin E, Pankow JS, B Windham G. "Sex Differences in the Association of Diabetes With Cardiovascular Disease Outcomes Among African-American and White Participants in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2018;187(3):403-410.
Hong J, Hatchell KE, Bradfield JP, et al. "Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations." J Clin Endocrinol Metab. 2018;103(4):1380-1392.
Chang PP, Wruck LM, Shahar E, et al. "Trends in Hospitalizations and Survival of Acute Decompensated Heart Failure in Four US Communities (2005-2014): ARIC Study Community Surveillance." Circulation. 2018;138(1):12-24.
2019
Yu Z, Rebholz CM, Wong E, Chen Y, Matsushita K, Coresh JJ. "Association Between Hypertension and Kidney Function Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2019;74(3):310-319.
Oliver-Williams C, Vladutiu CJ, Loehr LR, Rosamond WD. "The Association Between Parity and Subsequent Cardiovascular Disease in Women: The Atherosclerosis Risk in Communities Study." J Womens Health (Larchmt). 2019;28(5):721-727.
Dearborn-Tomazos JL, Wu A, Steffen LM, et al. "Association of Dietary Patterns in Midlife and Cognitive Function in Later Life in US Adults Without Dementia." JAMA Netw Open. 2019;2(12):e1916641.
Oyenuga AO, Folsom AR, Lutsey PL. "Association of Life's Simple 7 with reduced clinically manifest abdominal aortic aneurysm: The ARIC study." Vasc Med. 2019;24(3):224-229.
Cuthbertson CC, Tan X, Heiss G, Kucharska-Newton AMaria, Nichols HB, Kubota Y. "Associations of Leisure-Time Physical Activity and Television Viewing With Life Expectancy Free of Nonfatal Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2019;8(18):e012657.
de Larriva APArenas, Alonso A, Norby FL, Roetker NS. "Circulating ceruloplasmin, ceruloplasmin-associated genes and the incidence of venous thromboembolism in the Atherosclerosis Risk in Communities study." J Thromb Haemost. 2019;17(5):818-826.
Wang H, Nandakumar P, Tekola-Ayele F, et al. "Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31." Eur J Hum Genet. 2019;27(2):269-277.
George KM, Folsom AR, Steffen LM, Wagenknecht LE. "Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey: 1985-2015 vs The Atherosclerosis Risk in Communities Study Cohort: 1987-2015." Ethn Dis. 2019;29(1):47-52.
Spracklen CN, Karaderi T, Yaghootkar H, et al. "Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
Irvin MR, Sitlani CM, Floyd JS, et al. "Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group." Am J Hypertens. 2019;32(12):1146-1153.
Irvin MR, Sitlani CM, Noordam R, et al. "Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry." Pharmacogenomics J. 2019;19(1):97-108.
Grams ME, Surapaneni A, Ballew SH, et al. " Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis." J Am Soc Nephrol. 2019;30(10):2027-2036.
Lindström S, Brody JA, Turman C, et al. "A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Fashanu OE, Zhao D, Schneider ALC, et al. "Mid-life serum Vitamin D concentrations were associated with incident dementia but not late-life neuropsychological performance in the Atherosclerosis Risk in Communities (ARIC) Study." BMC Neurol. 2019;19(1):244.
Whitman IR, Vittinghoff E, Defilippi CR, et al. "NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure." J Am Heart Assoc. 2019;8(7):e010868.
Pendergrass SA, Buyske S, Jeff JM, et al. "A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans." PLoS One. 2019;14(12):e0226771.
Loehr LR, Soliman EZ, Poon AK, et al. "The prevalence of atrial fibrillation on 48-hour ambulatory electrocardiography in African Americans compared to Whites: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2019;216:1-8.
Zhao D, Post WS, Blasco-Colmenares E, et al. "Racial Differences in Sudden Cardiac Death." Circulation. 2019;139(14):1688-1697.
Deal JA, Sharrett ARichey, Albert M, et al. "Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study." Alzheimers Dement. 2019;15(3):477-486.
Alonso A, Yu B, Sun YV, et al. "Serum Metabolomics and Incidence of Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2019;123(12):1955-1961.
Muller CJ, Alonso A, Forster J, et al. "Stroke Incidence and Survival in American Indians, Blacks, and Whites: The Strong Heart Study and Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2019;8(12):e010229.
Caughey MC, Derebail VK, Key NS, Reiner AP, Gottesman RF, Kshirsagar AV. "Thirty-year risk of ischemic stroke in individuals with sickle cell trait and modification by chronic kidney disease: The atherosclerosis risk in communities (ARIC) study." Am J Hematol. 2019;94(12):1306-1313.
Kowalski MH, Qian H, Hou Z, et al. "Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations." PLoS Genet. 2019;15(12):e1008500.
2021
Hyacinth HI, Franceschini N, Seals SR, et al. "Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals." JAMA Netw Open. 2021;4(1):e2030435.
Selvaraj S, Claggett B, Minamisawa M, et al. "Atrial Fibrillation and Ischemic Stroke With the Amyloidogenic V122I Transthyretin Variant Among Black Americans." J Am Coll Cardiol. 2021;78(1):89-91.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Luo S, Feofanova EV, Tin A, et al. "Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension." Kidney Int. 2021;100(2):430-439.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.

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