Pulse lineResearch With Heart Logo

ARIC Publications

Filters: Keyword is Polymorphism, Single Nucleotide  [Clear All Filters]
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
Guo L, Akahori H, Harari E, et al. "CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis." J Clin Invest. 2018;128(3):1106-1124.
Guo Y, Lanktree MB, Taylor KC, Hakonarson H, Lange LA, Keating BJ. "Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals." Hum Mol Genet. 2013;22(1):184-201.
Guo D-C, Grove ML, Prakash SK, et al. "Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections." Am J Hum Genet. 2016;99(3):762-769.
Guan W, Steffen BT, Lemaitre RN, et al. "Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium." Circ Cardiovasc Genet. 2014;7(3):321-331.
Grove ML, Yu B, Cochran BJ, et al. "Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium." PLoS One. 2013;8(7):e68095.
Gregson JM, Freitag DF, Surendran P, et al. "Genetic invalidation of Lp-PLA as a therapeutic target: Large-scale study of five functional Lp-PLA-lowering alleles." Eur J Prev Cardiol. 2017;24(5):492-504.
Grallert H, Dupuis J, Bis JC, et al. "Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies." Eur Heart J. 2012;33(2):238-51.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Gordon-Larsen P, Lim U, et al. "The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study." Diabetes. 2013;62(5):1763-7.
Gorski M, van der Most PJ, Teumer A, et al. "1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function." Sci Rep. 2017;7:45040.
Gong J, Nishimura KK, Fernández-Rhodes L, et al. "Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI." Int J Obes (Lond). 2018;42(3):384-390.
Gong J, Schumacher F, Lim U, et al. "Fine Mapping and Identification of BMI Loci in African Americans." Am J Hum Genet. 2013;93(4):661-71.
Gharib SA, Loth DW, Artigas MSoler, et al. "Integrative pathway genomics of lung function and airflow obstruction." Hum Mol Genet. 2015;24(23):6836-48.
Gaulton KJ, Ferreira T, Lee Y, et al. "Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci." Nat Genet. 2015;47(12):1415-25.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
Ganesh SK, Chasman DI, Larson MG, et al. "Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations." Am J Hum Genet. 2014;95(1):49-65.
Ganesh SK, Zakai NA, van Rooij FJA, et al. "Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium." Nat Genet. 2009;41(11):1191-8.
Fu W, O'Connor TD, Jun G, et al. "Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants." Nature. 2013;493(7431):216-20.
Fretts AM, Follis JL, Nettleton JA, et al. "Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians." Am J Clin Nutr. 2015;102(5):1266-78.
Franceschini N, Muallem H, Rose KM, Boerwinkle E, Maeda N. "Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2009;7(3):496-8.
Franceschini N, Fox E, Zhang Z, et al. "Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations." Am J Hum Genet. 2013;93(3):545-54.
Franceschini N, Giambartolomei C, de Vries PS, et al. "GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes." Nat Commun. 2018;9(1):5141.
Franceschini N, North KE, Arnett D, et al. "The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study." Am J Hypertens. 2009;22(5):552-8.
Franceschini N, Hu Y, Reiner AP, et al. "Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study." PLoS One. 2014;9(12):e113203.
Foroud T, Lai D, Koller D, et al. "Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7." Stroke. 2014;45(11):3194-9.
Fornage M, Debette S, Bis JC, et al. "Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium." Ann Neurol. 2011;69(6):928-39.
Folsom AR, Tang W, George KM, Heckbert SR, Maclehose RF, Cushman M. "Prospective study of γ' fibrinogen and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Thromb Res. 2016;139:44-9.
Folsom AR, Pankow JS, Peacock JM, Bielinski SJ, Heiss G, Boerwinkle E. "Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2008;31(5):905-9.
Folsom AR, Nambi V, Pankow JS, et al. "Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2012;224(2):435-9.
Folsom AR, Cushman M, Tsai MY, Heckbert SR, Aleksic N. "Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism." Am J Hematol. 2002;71(4):285-90.
Folsom AR, Tang W, Roetker NS, Heckbert SR, Cushman M. "Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2015;90(11):1047-51.
Folsom AR, Tang W, Weng L-C, Roetker NS, Cushman M, Basu S. "Replication of a genetic risk score for venous thromboembolism in whites but not in African Americans." J Thromb Haemost. 2016;14(1):83-8.
Folsom AR, Roetker NS, Kelley ST, Tang W. "Failure to replicate thrombomodulin genetic variant predictors of venous thromboembolism in African Americans." Blood. 2017;130(5):688-690.
Fesinmeyer MD, North KE, Lim U, et al. "Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study." BMC Med Genet. 2013;14:6.
Fesinmeyer MD, North KE, Ritchie MD, et al. "Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study." Obesity (Silver Spring). 2013;21(4):835-46.
Fesinmeyer MD, Meigs JB, North KE, et al. "Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study." BMC Med Genet. 2013;14:98.
Fernández-Rhodes L, Malinowski JR, Wang Y, et al. "The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis." PLoS One. 2018;13(7):e0200486.
Feofanova EV, Yu B, Metcalf GA, et al. "Sequence-Based Analysis of Lipid-Related Metabolites in a Multiethnic Study." Genetics. 2018;209(2):607-616.
Feitosa MF, Kraja AT, Chasman DI, et al. "Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries." PLoS One. 2018;13(6):e0198166.
Fedorowski A, Franceschini N, Brody J, et al. "Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium." Eur Heart J. 2012;33(18):2331-41.
Evans DS, Avery CL, Nalls MA, et al. "Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans." Hum Mol Genet. 2016;25(19):4350-4368.
Evans DM, Brion MJo A, Paternoster L, et al. "Mining the human phenome using allelic scores that index biological intermediates." PLoS Genet. 2013;9(10):e1003919.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Evangelou E, Gao H, Chu C, et al. "New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav. 2019;3(9):950-961.
Escott-Price V, Bellenguez C, San Wang L-, et al. "Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease." PLoS One. 2014;9(6):e94661.
Ellis J, Lange EM, Li J, et al. "Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans." Hum Genet. 2014;133(8):985-95.
Ellinor PT, Lunetta KL, Glazer NL, et al. "Common variants in KCNN3 are associated with lone atrial fibrillation." Nat Genet. 2010;42(3):240-4.
Ellinor PT, Lunetta KL, Albert CM, et al. "Meta-analysis identifies six new susceptibility loci for atrial fibrillation." Nat Genet. 2012;44(6):670-5.
Ellervik C, Roselli C, Christophersen IE, et al. "Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study." JAMA Cardiol. 2019;4(2):144-152.
Eldomery MK, Coban-Akdemir Z, Harel T, et al. "Lessons learned from additional research analyses of unsolved clinical exome cases." Genome Med. 2017;9(1):26.
Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, et al. "Genome-wide association analysis identifies multiple loci related to resting heart rate." Hum Mol Genet. 2010;19(19):3885-94.
Ehret GB, Ferreira T, Chasman DI, et al. "The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals." Nat Genet. 2016;48(10):1171-1184.
Dumitrescu L, Carty CL, Franceschini N, et al. "Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study." Ann Hum Genet. 2013;77(5):416-25.
Dumitrescu L, Carty CL, Franceschini N, et al. "No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population." Hum Genet. 2013;132(12):1427-31.
Duan Q, Liu EYi, Auer PL, et al. "Imputation of coding variants in African Americans: better performance using data from the exome sequencing project." Bioinformatics. 2013;29(21):2744-9.
Dong J, Yang J, Tranah G, et al. "Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults." Medicine (Baltimore). 2015;94(47):e1892.
Dong C, Wei P, Jian X, Gibbs R, Boerwinkle E, Wang K. "Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies." Hum Mol Genet. 2015;24(8):2125-37.
Dong J, Wyss A, Yang J, et al. "Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans." Mol Neurobiol. 2017;54(10):8021-8032.
Do R, Willer CJ, Schmidt EM, et al. "Common variants associated with plasma triglycerides and risk for coronary artery disease." Nat Genet. 2013;45(11):1345-52.
Divaris K, Monda KL, North KE, et al. "Exploring the genetic basis of chronic periodontitis: a genome-wide association study." Hum Mol Genet. 2013;22(11):2312-24.
Dichgans M, Malik R, König IR, et al. "Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants." Stroke. 2014;45(1):24-36.
Mahajan A, Go MJin, Zhang W, et al. "Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility." Nat Genet. 2014;46(3):234-44.
Deo RC, Wilson JG, Xing C, et al. "Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans." PLoS One. 2011;6(1):e14581.
Deo R, Nalls MA, Avery CL, et al. "Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants." Heart Rhythm. 2013;10(3):401-8.
Demirkan A, Lahti J, Direk N, et al. "Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies." Psychol Med. 2016;46(8):1613-23.
Demerath EW, Lutsey PL, Monda KL, et al. "Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study." Obesity (Silver Spring). 2011;19(9):1866-72.
Demerath EW, Liu C-T, Franceschini N, et al. "Genome-wide association study of age at menarche in African-American women." Hum Mol Genet. 2013;22(16):3329-46.
Dehghan A, Bis JC, White CC, et al. "Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium." PLoS One. 2016;11(3):e0144997.
Dehghan A, Yang Q, Peters A, et al. "Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts." Circ Cardiovasc Genet. 2009;2(2):125-33.
Dehghan A, Köttgen A, Yang Q, et al. "Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study." Lancet. 2008;372(9654):1953-61.
Debette S, Verbaas CAIbrahim, Bressler J, et al. "Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium." Biol Psychiatry. 2015;77(8):749-63.
de Vries PS, Chasman DI, Sabater-Lleal M, et al. "A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration." Hum Mol Genet. 2016;25(2):358-70.
de Vries PS, Yu B, Feofanova EV, et al. "Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study." Hum Mol Genet. 2017;26(17):3442-3450.
de Vries PS, Sabater-Lleal M, Huffman JE, et al. "A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology." Blood. 2019;133(9):967-977.
de Haan HG, A Vlieg vanHylckama, Lotta LA, et al. "Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes." J Thromb Haemost. 2018;16(12):2432-2441.
Day FR, Thompson DJ, Helgason H, et al. "Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk." Nat Genet. 2017;49(6):834-841.
Davies G, Lam M, Harris SE, et al. "Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function." Nat Commun. 2018;9(1):2098.
Davies G, Armstrong N, Bis JC, et al. "Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949)." Mol Psychiatry. 2015;20(2):183-92.
David SP, Hamidovic A, Chen GK, et al. "Genome-wide meta-analyses of smoking behaviors in African Americans." Transl Psychiatry. 2012;2:e119.
Dastani Z, Johnson T, Kronenberg F, et al. "The shared allelic architecture of adiponectin levels and coronary artery disease." Atherosclerosis. 2013;229(1):145-8.