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ARIC Publications

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Journal Article
Gupta DK, Skali H, Claggett B, et al. "Heart failure risk across the spectrum of ankle-brachial index: the ARIC study (Atherosclerosis Risk In Communities)." JACC Heart Fail. 2014;2(5):447-54.
Shah AM, Claggett B, Loehr LR, et al. "Heart Failure Stages Among Older Adults in the Community: The Atherosclerosis Risk in Communities Study." Circulation. 2017;135(3):224-240.
Fyfe-Johnson AL, Muller CJ, Alonso A, et al. "Heart Rate Variability and Incident Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1452-8.
Alonso A, Huang X, Mosley TH, Heiss G. "Heart rate variability and the risk of Parkinson disease: The Atherosclerosis Risk in Communities study." Ann Neurol. 2015;77(5):877-83.
Dekker JM, Crow RS, Hannan PJ, Schouten EG, Folsom AR. "Heart rate-corrected QT interval prolongation predicts risk of coronary heart disease in black and white middle-aged men and women: the ARIC study." J Am Coll Cardiol. 2004;43(4):565-71.
Folsom AR, Nieto FJ, Sorlie P, Chambless LE, Graham DY. "Helicobacter pylori seropositivity and coronary heart disease incidence. Atherosclerosis Risk In Communities (ARIC) Study Investigators." Circulation. 1998;98(9):845-50.
Kucharska-Newton AM, Couper DJ, Pankow JS, et al. "Hemostasis, inflammation, and fatal and nonfatal coronary heart disease: long-term follow-up of the atherosclerosis risk in communities (ARIC) cohort." Arterioscler Thromb Vasc Biol. 2009;29(12):2182-90.
Sturgeon JD, Folsom AR, Longstreth WT, Shahar E, Rosamond WD, Cushman M. "Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort." Stroke. 2008;39(8):2268-73.
Pankow JS, Boerwinkle E, Adams PC, et al. "HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study." Transl Res. 2008;152(1):3-10.
McEvoy JW, Chen Y, Nambi V, et al. "High-Sensitivity Cardiac Troponin T and Risk of Hypertension." Circulation. 2015;132(9):825-33.
Shahar E, Redline S, Young T, et al. "Hormone replacement therapy and sleep-disordered breathing." Am J Respir Crit Care Med. 2003;167(9):1186-92.
Cowan LT, Alonso A, Pankow JS, Folsom AR, Rosamond WD, Gottesman RF. "Hospitalized Infection as a Trigger for Acute Ischemic Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1612-7.
Young SE, Mainous AG, Carnemolla M. "Hyperinsulinemia and cognitive decline in a middle-aged cohort." Diabetes Care. 2006;29(12):2688-93.
McAdams-Demarco MA, Maynard JW, Baer AN, Coresh J. "Hypertension and the risk of incident gout in a population-based study: the atherosclerosis risk in communities cohort." J Clin Hypertens (Greenwich). 2012;14(10):675-9.
McAdams DeMarco M, Coresh J, Woodward M, et al. "Hypertension status, treatment, and control among spousal pairs in a middle-aged adult cohort." Am J Epidemiol. 2011;174(7):790-6.
Grams ME, Rebholz CM, McMahon B, et al. "Identification of incident CKD stage 3 in research studies." Am J Kidney Dis. 2014;64(2):214-21.
Begum F, Ruczinski I, Li S, et al. "Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort." Genet Epidemiol. 2016;40(1):81-8.
Stevens J, Cai J, Evans GW. "Impact of body mass index on changes in common carotid artery wall thickness." Obes Res. 2002;10(10):1000-7.
Sarnowski C, Leong A, Raffield LM, et al. "Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program." Am J Hum Genet. 2019;105(4):706-718.
Rasmussen-Torvik LJ, Alonso A, Li M, et al. "Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose." Genet Epidemiol. 2010;34(7):665-73.
Lutsey PL, Chen N, Mirabelli MC, et al. "Impaired Lung Function, Lung Disease, and Risk of Incident Dementia." Am J Respir Crit Care Med. 2019;199(11):1385-1396.
Kim S, Cai J. "Improving the efficiency of estimation in the additive hazards model for stratified case-cohort design with multiple diseases." Stat Med. 2016;35(2):282-93.
Jensen PN, Gronroos NN, Chen LYee, Folsom AR, deFilippi C, Heckbert SR. "Incidence of and risk factors for sick sinus syndrome in the general population." J Am Coll Cardiol. 2014;64(6):531-8.
Alonso A, Agarwal SK, Soliman EZ, et al. "Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2009;158(1):111-7.
Maynard JW, McAdams DeMarco MA, Baer AN, et al. "Incident gout in women and association with obesity in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Med. 2012;125(7):717.e9-717.e17.
Nettleton JA, Steffen LM, Loehr LR, Rosamond WD, Folsom AR. "Incident heart failure is associated with lower whole-grain intake and greater high-fat dairy and egg intake in the Atherosclerosis Risk in Communities (ARIC) study." J Am Diet Assoc. 2008;108(11):1881-7.
Pandey A, Patel KV, Vongpatanasin W, et al. "Incorporation of Biomarkers Into Risk Assessment for Allocation of Antihypertensive Medication According to the 2017 ACC/AHA High Blood Pressure Guideline: A Pooled Cohort Analysis." Circulation. 2019;140(25):2076-2088.
Bash LD, Erlinger TP, Coresh J, Marsh-Manzi J, Folsom AR, Astor BC. "Inflammation, hemostasis, and the risk of kidney function decline in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2009;53(4):596-605.
Nadruz W, Gonçalves A, Claggett B, et al. "Influence of cigarette smoking on cardiac biomarkers: the Atherosclerosis Risk in Communities (ARIC) Study." Eur J Heart Fail. 2016;18(6):629-37.
Graff M, Gordon-Larsen P, Lim U, et al. "The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study." Diabetes. 2013;62(5):1763-7.
Bressler J, Fornage M, Hanis CL, et al. "The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts." BMC Med Genet. 2009;10:56.
Demerath EW, Lutsey PL, Monda KL, et al. "Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study." Obesity (Silver Spring). 2011;19(9):1866-72.
Ma Y, Follis JL, Smith CE, et al. "Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium." Am J Clin Nutr. 2016;103(2):567-78.
Mok Y, Ballew SH, Bash LD, et al. "International Validation of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention in Post-MI Patients: A Collaborative Analysis of the Chronic Kidney Disease Prognosis Consortium and the Risk Validation Scientific Committee." J Am Heart Assoc. 2018;7(14).
Chatterjee R, Davenport CA, Raffield LM, et al. "KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts." PLoS One. 2018;13(8):e0203213.
Rebholz CM, Coresh JJ, Ballew SH, McMahon B, Whelton SP, Selvin E. "Kidney Failure and ESRD in the Atherosclerosis Risk in Communities (ARIC) Study: Comparing Ascertainment of Treated and Untreated Kidney Failure in a Cohort Study." Am J Kidney Dis. 2015;66(2):231-9.
Daya N, Voskertchian A, Schneider ALC, et al. "Kidney Function and Fracture Risk: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2016;67(2):218-226.
Secora A, G Alexander C, Ballew SH, Coresh JJ. "Kidney Function, Polypharmacy, and Potentially Inappropriate Medication Use in a Community-Based Cohort of Older Adults." Drugs Aging. 2018;35(8):735-750.
Alexander N, Matsushita K, Sang Y, Ballew S, Mahmoodi BK, Astor BC. "Kidney measures with diabetes and hypertension on cardiovascular disease: the Atherosclerosis Risk in Communities Study." Am J Nephrol. 2015;41(4-5):409-17.
Iribarren C, Sempos CT, Eckfeldt JH, Folsom AR. "Lack of association between ferritin level and measures of LDL oxidation: the ARIC study. Atherosclerosis Risk in Communities." Atherosclerosis. 1998;139(1):189-95.
Bielinski SJ, Pankow JS, Boerwinkle E, Bray MS, Kao LWH, Folsom AR. "Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study." Acta Diabetol. 2008;45(3):179-82.
Juraschek SP, Shantha GPalamaner, Chu AY, et al. "Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study." PLoS One. 2013;8(1):e55113.
Sarnowski C, Cousminer DL, Franceschini N, et al. "Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
Sung YJ, Winkler TW, Fuentes Lde Las, et al. "A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure." Am J Hum Genet. 2018;102(3):375-400.
Fox ER, Taylor HA, Benjamin EJ, et al. "Left ventricular mass indexed to height and prevalent MRI cerebrovascular disease in an African American cohort: the Atherosclerotic Risk in Communities study." Stroke. 2005;36(3):546-50.
Schmidt MI, Duncan BB, Vigo A, et al. "Leptin and incident type 2 diabetes: risk or protection?" Diabetologia. 2006;49(9):2086-96.
Carson A P, Carson A PL, Rose KM, et al. "Lifetime prevalence of migraine and other headaches lasting 4 or more hours: the Atherosclerosis Risk in Communities (ARIC) study." Headache. 2004;44(1):20-8.
Bell EJ, Lutsey PL, Basu S, Cushman M, Heckbert SR, Lloyd-Jones DM. "Lifetime Risk of Venous Thromboembolism in Two Cohort Studies." Am J Med. 2016;129(3):339.e19-26.
Schreiner PJ, Chambless LE, Brown SA, Watson RL, Toole J, Heiss G. "Lipoprotein(a) as a correlate of stroke and transient ischemic attack prevalence in a biracial cohort: the ARIC Study. Atherosclerosis Risk in Communities." Ann Epidemiol. 1994;4(5):351-9.
Schreiner PJ. "Lipoprotein(a) as a risk factor for preclinical atherosclerotic disease in a biracial cohort: the Atherosclerosis Risk in Communities (ARIC) Study." Chem Phys Lipids. 1994;67-68:405-10.
Nambi V, Hoogeveen RC, Chambless L, et al. "Lipoprotein-associated phospholipase A2 and high-sensitivity C-reactive protein improve the stratification of ischemic stroke risk in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2009;40(2):376-81.
Ballantyne CM, Hoogeveen RC, Bang H, et al. "Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2004;109(7):837-42.
Schneider ALC, Lazo M, Ndumele CE, et al. "Liver enzymes, race, gender and diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study." Diabet Med. 2013;30(8):926-33.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
Wang SY, Tan ASL, Claggett B, et al. "Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.
Silva GE, An M-W, Goodwin JL, et al. "Longitudinal evaluation of sleep-disordered breathing and sleep symptoms with change in quality of life: the Sleep Heart Health Study (SHHS)." Sleep. 2009;32(8):1049-57.
Avery CL, Mills KT, Chambless LE, et al. "Long-term association between self-reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study." Eur J Heart Fail. 2010;12(3):232-8.
Pellanda LC, Duncan BB, Vigo A, Rose K, Folsom AR, Erlinger TP. "Low birth weight and markers of inflammation and endothelial activation in adulthood: the ARIC study." Int J Cardiol. 2009;134(3):371-7.
Aggarwal V, Schneider ALC, Selvin E. "Low hemoglobin A(1c) in nondiabetic adults: an elevated risk state?" Diabetes Care. 2012;35(10):2055-60.
Folsom AR, Ohira T, Yamagishi K, Cushman M. "Low protein C and incidence of ischemic stroke and coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study." J Thromb Haemost. 2009;7(11):1774-8.
Alam AB, Lutsey PL, Gottesman RF, Tin A, Alonso A. "Low Serum Magnesium is Associated with Incident Dementia in the ARIC-NCS Cohort." Nutrients. 2020;12(10).
Gansevoort RT, Matsushita K, van der Velde M, et al. "Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts." Kidney Int. 2011;80(1):93-104.
van der Velde M, Matsushita K, Coresh J, et al. "Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts." Kidney Int. 2011;79(12):1341-52.
Wu A, Coresh JJ, Selvin E, et al. "Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community." J Am Heart Assoc. 2017;6(1).
Liao D, Carnethon M, Evans GW, Cascio WE, Heiss G. "Lower heart rate variability is associated with the development of coronary heart disease in individuals with diabetes: the atherosclerosis risk in communities (ARIC) study." Diabetes. 2002;51(12):3524-31.
Duncan BB, Schmidt M I, Pankow JS, et al. "Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study." Diabetes. 2003;52(7):1799-805.
Sumida K, Kwak L, Grams ME, et al. "Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2017;70(5):675-685.
Hozawa A, Billings JL, Shahar E, Ohira T, Rosamond WD, Folsom AR. "Lung function and ischemic stroke incidence: the Atherosclerosis Risk in Communities study." Chest. 2006;130(6):1642-9.
Kang S, Cai J, Chambless L. "Marginal additive hazards model for case-cohort studies with multiple disease outcomes: an application to the Atherosclerosis Risk in Communities (ARIC) study." Biostatistics. 2013;14(1):28-41.
Schmidt MI, Duncan BB, Sharrett AR, et al. "Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study." Lancet. 1999;353(9165):1649-52.
Boland LL, Shahar E, Iber C, Knopman DS, Kuo TF, Nieto JF. "Measures of cognitive function in persons with varying degrees of sleep-disordered breathing: the Sleep Heart Health Study." J Sleep Res. 2002;11(3):265-72.
Marioni RE, McRae AF, Bressler J, et al. "Meta-analysis of epigenome-wide association studies of cognitive abilities." Mol Psychiatry. 2018;23(11):2133-2144.
Bis JC, Kavousi M, Franceschini N, et al. "Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque." Nat Genet. 2011;43(10):940-7.
Carty CL, Keene KL, Cheng Y-C, et al. "Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans." Stroke. 2015;46(8):2063-8.
Ahmed RL, Schmitz KH, Anderson KE, Rosamond WD, Folsom AR. "The metabolic syndrome and risk of incident colorectal cancer." Cancer. 2006;107(1):28-36.
Decker JJ, Norby FL, Rooney MR, et al. "Metabolic Syndrome and Risk of Ischemic Stroke in Atrial Fibrillation: ARIC Study." Stroke. 2019;50(11):3045-3050.
Zheng Y, Yu B, Alexander D, Steffen LM, Nettleton JA. "Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2014;99(6):1470-8.
Gondalia R, Baldassari A, Holliday KM, et al. "Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation." Environ Int. 2019;132:104723.
Jones SB, Loehr LR, Avery CL, Gottesman RF, Wruck L, Shahar E. "Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study." Stroke. 2015;46(11):3124-30.