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ARIC Publications

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Artigas MSoler, Loth DW, Wain LV, et al. "Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function." Nat Genet. 2011;43(11):1082-90.
Fornage M, Debette S, Bis JC, et al. "Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium." Ann Neurol. 2011;69(6):928-39.
Tin A, Woodward OM, Kao W H L, et al. "Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele." Hum Mol Genet. 2011;20(20):4056-68.
Reiner AP, Lettre G, Nalls MA, et al. "Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT)." PLoS Genet. 2011;7(6):e1002108.
Cornelis MC, Monda KL, Yu K, et al. "Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption." PLoS Genet. 2011;7(4):e1002033.
Arking DE, M Junttila J, Goyette P, et al. "Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals." PLoS Genet. 2011;7(6):e1002158.
Demerath EW, Lutsey PL, Monda KL, et al. "Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study." Obesity (Silver Spring). 2011;19(9):1866-72.
Bis JC, Kavousi M, Franceschini N, et al. "Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque." Nat Genet. 2011;43(10):940-7.
O'Seaghdha CM, Parekh RS, Hwang S-J, et al. "The MYH9/APOL1 region and chronic kidney disease in European-Americans." Hum Mol Genet. 2011;20(12):2450-6.
Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM. "Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study." Hypertension. 2011;57(2):167-73.
Garaas R, Moss KL, Fisher EL, et al. "Prevalence of visible third molars with caries experience or periodontal pathology in middle-aged and older Americans." J Oral Maxillofac Surg. 2011;69(2):463-70.
Evans K, Coresh J, Bash LD, et al. "Race differences in access to health care and disparities in incident chronic kidney disease in the US." Nephrol Dial Transplant. 2011;26(3):899-908.
Selvin E, Steffes MW, Ballantyne CM, Hoogeveen RC, Coresh J, Brancati FL. "Racial differences in glycemic markers: a cross-sectional analysis of community-based data." Ann Intern Med. 2011;154(5):303-9.
Chatterjee R, Yeh H-C, Shafi T, et al. "Serum potassium and the racial disparity in diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2011;93(5):1087-91.
Deo RC, Wilson JG, Xing C, et al. "Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans." PLoS One. 2011;6(1):e14581.
Foraker RE, Rose KM, Kucharska-Newton AM, Ni H, Suchindran CM, Whitsel EA. "Variation in rates of fatal coronary heart disease by neighborhood socioeconomic status: the atherosclerosis risk in communities surveillance (1992-2002)." Ann Epidemiol. 2011;21(8):580-8.
Knopman DS, Penman AD, Catellier DJ, et al. "Vascular risk factors and longitudinal changes on brain MRI: the ARIC study." Neurology. 2011;76(22):1879-85.
Cheng C-Y, Reich D, Coresh J, et al. "Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study." Obesity (Silver Spring). 2010;18(3):563-72.
Weitzman S, Wang C-H, Pankow JS, Schmidt MI, Brancati FL. "Are measures of height and leg length related to incident diabetes mellitus? The ARIC (Atherosclerosis Risk in Communities) study." Acta Diabetol. 2010;47(3):237-42.
Speliotes EK, Willer CJ, Berndt SI, et al. "Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index." Nat Genet. 2010;42(11):937-48.
Smith NL, Felix JF, Morrison AC, et al. "Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium." Circ Cardiovasc Genet. 2010;3(3):256-66.
Hardy DS, Hoelscher DM, Aragaki C, et al. "Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: the Atherosclerosis Risk in Communities study." Ann Epidemiol. 2010;20(8):610-6.
Kingah PL, Luu HN, Volcik KA, Morrison AC, Nettleton JA, Boerwinkle E. "Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study." Hypertens Res. 2010;33(2):165-9.
Yatsuya H, Yamagishi K, North KE, Brancati FL, Stevens J, Folsom AR. "Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study." J Epidemiol. 2010;20(5):347-54.
Teslovich TM, Musunuru K, Smith AV, et al. "Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
Gottesman RF, Coresh J, Catellier DJ, et al. "Blood pressure and white-matter disease progression in a biethnic cohort: Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2010;41(1):3-8.
Soranzo N, Sanna S, Wheeler E, et al. "Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways." Diabetes. 2010;59(12):3229-39.
Akoudad S, Szklo M, McAdams MA, et al. "Correlates of kidney stone disease differ by race in a multi-ethnic middle-aged population: the ARIC study." Prev Med. 2010;51(5):416-20.
Rasmussen-Torvik LJ, Yatsuya H, Selvin E, Alonso A, Folsom AR. "Demographic and cardiovascular risk factors modify association of fasting insulin with incident coronary heart disease and ischemic stroke (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2010;105(10):1420-5.
Alonso A, Nettleton JA, Ix JH, et al. "Dietary phosphorus, blood pressure, and incidence of hypertension in the atherosclerosis risk in communities study and the multi-ethnic study of atherosclerosis." Hypertension. 2010;55(3):776-84.
Bressler J, Folsom AR, Couper DJ, Volcik KA, Boerwinkle E. "Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2010;171(1):14-23.
Meyer TE, Verwoert GC, Hwang S-J, et al. "Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels." PLoS Genet. 2010;6(8).
Morrison AC, Felix JF, L Cupples A, et al. "Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium." Circ Cardiovasc Genet. 2010;3(3):248-55.
Zhu N, Pankow JS, Ballantyne CM, et al. "High-molecular-weight adiponectin and the risk of type 2 diabetes in the ARIC study." J Clin Endocrinol Metab. 2010;95(11):5097-104.
Lubitz SA, Sinner MF, Lunetta KL, et al. "Independent susceptibility markers for atrial fibrillation on chromosome 4q25." Circulation. 2010;122(10):976-84.
Roberts CB, Couper DJ, Chang PP, James SA, Rosamond WD, Heiss G. "Influence of life-course socioeconomic position on incident heart failure in blacks and whites: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2010;172(6):717-27.
Nettleton JA, McKeown NM, Kanoni S, et al. "Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies." Diabetes Care. 2010;33(12):2684-91.
Barbalic M, Dupuis J, Dehghan A, et al. "Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels." Hum Mol Genet. 2010;19(9):1863-72.
Avery CL, Mills KT, Chambless LE, et al. "Long-term association between self-reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study." Eur J Heart Fail. 2010;12(3):232-8.
Chamberlain AM, Agarwal SK, Ambrose M, Folsom AR, Soliman EZ, Alonso A. "Metabolic syndrome and incidence of atrial fibrillation among blacks and whites in the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2010;159(5):850-6.
Johnson AM, Rose KM, Elder GH, Chambless LE, Kaufman JS, Heiss G. "Military combat and burden of subclinical atherosclerosis in middle aged men: the ARIC study." Prev Med. 2010;50(5-6):277-81.
Johnson AM, Rose KM, Elder GH, Chambless LE, Kaufman JS, Heiss G. "Military combat and risk of coronary heart disease and ischemic stroke in aging men: The Atherosclerosis Risk in Communities (ARIC) study." Ann Epidemiol. 2010;20(2):143-50.
Chu AY, Coresh J, Arking DE, et al. "NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2010;53(3):510-6.
Rose KM, Couper D, Eigenbrodt ML, Mosley TH, A Sharrett R, Gottesman RF. "Orthostatic hypotension and cognitive function: the Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2010;34(1):1-7.
Franceschini N, Rose KM, Astor BC, Couper D, Vupputuri S. "Orthostatic hypotension and incident chronic kidney disease: the atherosclerosis risk in communities study." Hypertension. 2010;56(6):1054-9.
Bressler J, Kao LWH, Pankow JS, Boerwinkle E. "Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study." PLoS One. 2010;5(5):e10521.
Franceschini N, North KE, Arnett D, et al. "The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study." Am J Hypertens. 2009;22(5):552-8.
Dehghan A, Yang Q, Peters A, et al. "Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts." Circ Cardiovasc Genet. 2009;2(2):125-33.
Chamberlain AM, Schabath MB, Folsom AR. "Associations of chronic obstructive pulmonary disease with all-cause mortality in Blacks and Whites: the atherosclerosis risk in communities (ARIC) study." Ethn Dis. 2009;19(3):308-14.
Nettleton JA, Volcik KA, Hoogeveen RC, Boerwinkle E. "Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2009;203(1):214-20.
Alonso A, Steffen LM, Folsom AR. "Dairy intake and changes in blood pressure over 9 years: the ARIC study." Eur J Clin Nutr. 2009;63(10):1272-5.
Soliman EZ, Prineas RJ, Case DL, Zhang Z-M, Goff DC. "Ethnic distribution of ECG predictors of atrial fibrillation and its impact on understanding the ethnic distribution of ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2009;40(4):1204-11.
Yamagishi K, Folsom AR, Rosamond WD, Boerwinkle E. "A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study." Eur Heart J. 2009;30(10):1222-8.
Kao LWH, Arking DE, Post W, et al. "Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations." Circulation. 2009;119(7):940-51.
M Ikram A, Seshadri S, Bis JC, et al. "Genomewide association studies of stroke." N Engl J Med. 2009;360(17):1718-28.
Meyer TE, Shiffman D, Morrison AC, et al. "GOSR2 Lys67Arg is associated with hypertension in whites." Am J Hypertens. 2009;22(2):163-8.
Han E, Truesdale KP, Taber DR, Cai J, Juhaeri J, Stevens J. "Impact of overweight and obesity on hospitalization: race and gender differences." Int J Obes (Lond). 2009;33(2):249-56.
Alonso A, Agarwal SK, Soliman EZ, et al. "Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2009;158(1):111-7.
Bressler J, Fornage M, Hanis CL, et al. "The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts." BMC Med Genet. 2009;10:56.
Chichlowska KL, Rose KM, Diez-Roux AV, Golden SH, McNeill AM, Heiss G. "Life course socioeconomic conditions and metabolic syndrome in adults: the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 2009;19(12):875-83.
Monda KL, Ballantyne CM, North KE. "Longitudinal impact of physical activity on lipid profiles in middle-aged adults: the Atherosclerosis Risk in Communities Study." J Lipid Res. 2009;50(8):1685-91.
Franceschini N, Muallem H, Rose KM, Boerwinkle E, Maeda N. "Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2009;7(3):496-8.
Arking DE, Khera A, Xing C, et al. "Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population." PLoS One. 2009;4(1):e4333.
Rose KM, Suchindran CM, Foraker RE, et al. "Neighborhood disparities in incident hospitalized myocardial infarction in four U.S. communities: the ARIC surveillance study." Ann Epidemiol. 2009;19(12):867-74.
Heard-Costa NL, Zillikens CM, Monda KL, et al. "NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium." PLoS Genet. 2009;5(6):e1000539.
Chen H, Mosley TH, Alonso A, Huang X. "Plasma urate and Parkinson's disease in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2009;169(9):1064-9.
Reich D, Nalls MA, Kao LWH, et al. "Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene." PLoS Genet. 2009;5(1):e1000360.
Bidulescu A, Chambless LE, Siega-Riz A M, Zeisel SH, Heiss G. "Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study." Nutr J. 2009;8:14.
Alonso A, Mosley TH, Gottesman RF, Catellier D, Sharrett AR, Coresh J. "Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study." J Neurol Neurosurg Psychiatry. 2009;80(11):1194-201.
Volcik KA, Catellier D, Folsom AR, Matijevic N, Wasserman B, Boerwinkle E. "SELP and SELPLG genetic variation is associated with cell surface measures of SELP and SELPLG: the Atherosclerosis Risk in Communities Carotid MRI Study." Clin Chem. 2009;55(6):1076-82.
Yan Y, North KE, Ballantyne CM, et al. "Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study." Diabetes. 2009;58(1):285-9.
Benjamin EJ, Rice KM, Arking DE, et al. "Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry." Nat Genet. 2009;41(8):879-81.
Klos K, Shimmin L, Ballantyne C, et al. "APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels." Hum Mol Genet. 2008;17(13):2039-46.
Köttgen A, Hsu CC, Coresh J, et al. "The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults." Am J Kidney Dis. 2008;52(5):868-75.
Volcik KA, Ballantyne CM, Braun MC, Coresh J, Mosley TH, Boerwinkle E. "Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study." Am J Hypertens. 2008;21(5):533-8.
Catellier DJ, Aleksic N, Folsom AR, Boerwinkle E. "Atherosclerosis Risk in Communities (ARIC) Carotid MRI flow cytometry study of monocyte and platelet markers: intraindividual variability and reliability." Clin Chem. 2008;54(8):1363-71.
Assimes TL, Knowles JW, Priest JR, et al. "Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease." Hum Genet. 2008;123(4):399-408.
Pollitt RA, Kaufman JS, Rose KM, Diez-Roux AV, Zeng D, Heiss G. "Cumulative life course and adult socioeconomic status and markers of inflammation in adulthood." J Epidemiol Community Health. 2008;62(6):484-91.
Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. "Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study." Clin Pharmacol Ther. 2008;83(1):52-60.
Loehr LR, Rosamond WD, Chang PP, Folsom AR, Chambless LE. "Heart failure incidence and survival (from the Atherosclerosis Risk in Communities study)." Am J Cardiol. 2008;101(7):1016-22.