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ARIC Publications

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Ting J, Jiang K, Du S, et al. "Longitudinal Blood Pressure Patterns from Mid-to-Late Life and Late-life Hearing Loss in the Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2021.
Tin A, Walker KA, Bressler J, et al. "Association between Circulating Protein C Levels and Incident Dementia: The Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2021;55(4):306-315.
Tin A, Astor BC, Boerwinkle E, Hoogeveen RC, Coresh J, Kao LWH. "Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans." Nephrol Dial Transplant. 2013;28(6):1497-504.
Tin A, Woodward OM, Kao W H L, et al. "Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele." Hum Mol Genet. 2011;20(20):4056-68.
Tin A, Grams ME, Ashar FN, et al. "Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study." J Am Soc Nephrol. 2016;27(8):2467-73.
Tin A, Grams ME, Maruthur NM, et al. "Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(5):784-90.
Tin A, Balakrishnan P, Beaty TH, Boerwinkle E, Hoogeveen RC, Young JH. "GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2016;33(7):968-75.
Tin A, Marten J, Kuhns VLHalperin, et al. "Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels." Nat Genet. 2019;51(10):1459-1474.
Tin A, Li Y, Brody JA, et al. "Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels." Nat Commun. 2018;9(1):4228.
Tin A, Colantuoni E, Boerwinkle E, et al. "Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate." J Hum Genet. 2013;58(7):461-6.
Tin A, Scharpf R, Estrella MM, et al. "The Loss of Associates with Kidney Failure and Heart Failure." J Am Soc Nephrol. 2017;28(11):3345-3352.
Tin A, Yu B, Ma J, et al. "Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay." J Appl Lab Med. 2019;4(1):30-39.
Tin A, Grams ME, Maruthur NM, et al. "Results from the Atherosclerosis Risk in Communities study suggest that low serum magnesium is associated with incident kidney disease." Kidney Int. 2015;87(4):820-7.
Tin A, Köttgen A, Folsom AR, et al. "Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study." BMC Genet. 2015;16:56.
Tin A, Astor BC, Boerwinkle E, Hoogeveen RC, Coresh J, Kao W H L. "Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin." Hum Genet. 2013;132(6):619-27.
Tilling K, Smith G D, Chambless L, et al. "The relation between birth weight and intima-media thickness in middle-aged adults." Epidemiology. 2004;15(5):557-64.
Tilling K, Lawlor DA, Smith GDavey, Chambless L, Szklo M. "The relation between components of adult height and intimal-medial thickness in middle age: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2006;164(2):136-42.
Tilling K, Sterne JAC, Szklo M. "Estimating the effect of cardiovascular risk factors on all-cause mortality and incidence of coronary heart disease using G-estimation: the atherosclerosis risk in communities study." Am J Epidemiol. 2002;155(8):710-8.
Tikellis G, Anuradha S, Klein R, Wong T Y. "Association between physical activity and retinal microvascular signs: the Atherosclerosis Risk in Communities (ARIC) Study." Microcirculation. 2010;17(5):381-93.
Tikellis G, Arnett DK, Skelton TN, et al. "Retinal arteriolar narrowing and left ventricular hypertrophy in African Americans. the Atherosclerosis Risk in Communities (ARIC) study." Am J Hypertens. 2008;21(3):352-9.
Thyagarajan B, Brott M, Mink P, et al. "CYP1B1 and CYP19 gene polymorphisms and breast cancer incidence: no association in the ARIC study." Cancer Lett. 2004;207(2):183-9.
Thorvaldsen T, Claggett BL, Shah A, et al. "Predicting Risk in Patients Hospitalized for Acute Decompensated Heart Failure and Preserved Ejection Fraction: The Atherosclerosis Risk in Communities Study Heart Failure Community Surveillance." Circ Heart Fail. 2017;10(12).
Thorgeirsson TE, Gudbjartsson DF, Sulem P, et al. "A common biological basis of obesity and nicotine addiction." Transl Psychiatry. 2013;3:e308.
Thibord F, Song C, Pattee J, et al. FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer.. Vol. 19.; 2021. J Thromb Haemost 19(8).
Crosby J, Peloso GM, Auer PL, et al. "Loss-of-function mutations in APOC3, triglycerides, and coronary disease." N Engl J Med. 2014;371(1):22-31.
Teumer A, Li Y, Ghasemi S, et al. "Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria." Nat Commun. 2019;10(1):4130.
Teumer A, Chaker L, Groeneweg S, et al. "Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.
Teumer A, Tin A, Sorice R, et al. "Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes." Diabetes. 2016;65(3):803-17.
Teslovich TM, Musunuru K, Smith AV, et al. "Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
Terry JG, Hinson WH, Evans GW, Schreiner PJ, Hagaman AP, Crouse JR. "Evaluation of magnetic resonance imaging for quantification of intraabdominal fat in human beings by spin-echo and inversion-recovery protocols." Am J Clin Nutr. 1995;62(2):297-301.
Tereshchenko LG, Sotoodehnia N, Sitlani CM, et al. "Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)." J Am Heart Assoc. 2018;7(8).
Tereshchenko LG, Henrikson CA, Sotoodehnia N, et al. "Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study." J Am Heart Assoc. 2014;3(6):e001387.
Teramoto K, Santos M, Claggett B, et al. "Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis." PLoS Med. 2020;17(10):e1003361.
Teramoto K, Junior WNadruz, Matsushita K, et al. "Mid- to Late-Life Time-Averaged Cumulative Blood Pressure and Late-Life Cardiac Structure, Function, and Heart Failure." Hypertension. 2020;76(3):808-818.
Tennessen JA, Bigham AW, O'Connor TD, et al. "Evolution and functional impact of rare coding variation from deep sequencing of human exomes." Science. 2012;337(6090):64-9.
Haycock PC, Burgess S, Nounu A, et al. "Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study." JAMA Oncol. 2017;3(5):636-651.
Tell GS, Evans GW, Folsom AR, Shimakawa T, Carpenter MA, Heiss G. "Dietary fat intake and carotid artery wall thickness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1994;139(10):979-89.
Taylor KC, Carty CL, Dumitrescu L, et al. "Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study." BMC Genet. 2013;14:33.
Taylor HA, Clark BL, Garrison RJ, et al. "Relation of aortic valve sclerosis to risk of coronary heart disease in African-Americans." Am J Cardiol. 2005;95(3):401-4.
Taylor HA, Penman AD, Han H, et al. "Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2007;99(10):1413-20.
Tariq A, Chen J, Yu B, et al. "Metabolomics of Dietary Acid Load and Incident Chronic Kidney Disease." J Ren Nutr. 2021.
Tao R, Zeng D, Franceschini N, North KE, Boerwinkle E. "Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling." J Am Stat Assoc. 2015;110(510):560-572.
Tangri N, Grams ME, Levey AS, et al. "Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis." JAMA. 2016;315(2):164-74.
Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Tang O, Matsushita K, Coresh JJ, et al. "High-Sensitivity Cardiac Troponin I and T for Cardiovascular Risk Stratification in Adults With Diabetes." Diabetes Care. 2020;43(10):e144-e146.
Tang W, Cushman M, Green D, et al. "Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans." Am J Hematol. 2015;90(6):534-40.
Tang W, Morrison A, Wasserman BA, et al. "Association of SERPINA9 gene variants with carotid artery atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study." Int J Mol Epidemiol Genet. 2013;4(4):258-67.
Tang W, Stimson MRachel, Basu S, et al. "Burden of rare exome sequence variants in PROC gene is associated with venous thromboembolism: a population-based study." J Thromb Haemost. 2020;18(2):445-453.
Tang W, Yao L, Roetker NS, et al. "Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
Tang W, Yao L, Hoogeveen RC, et al. "The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study." Angiology. 2019;70(2):130-140.
Tang W, Saratzis A, Pattee J, et al. "Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG." Eur J Vasc Endovasc Surg. 2020;59(1):92-97.
Tang O, Matsushita K, Coresh JJ, et al. "High-Sensitivity Cardiac Troponin I for Risk Stratification in Older Adults." J Am Geriatr Soc. 2020.
Tang W, Kowgier M, Loth DW, et al. "Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function." PLoS One. 2014;9(7):e100776.
Tang O, Daya N, Matsushita K, et al. "Performance of High-Sensitivity Cardiac Troponin Assays to Reflect Comorbidity Burden and Improve Mortality Risk Stratification in Older Adults With Diabetes." Diabetes Care. 2020;43(6):1200-1208.
Tang W, Teichert M, Chasman DI, et al. "A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium." Genet Epidemiol. 2013;37(5):512-521.
Tang W, Schwienbacher C, Lopez LM, et al. "Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease." Am J Hum Genet. 2012;91(1):152-62.
Tang W, Basu S, Kong X, et al. "Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study." Blood. 2010;116(23):5032-6.
Tandon A, Chen CJ, Penman A, et al. "African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans." Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005.
Tande AJ, Platz EA, Folsom AR. "The metabolic syndrome is associated with reduced risk of prostate cancer." Am J Epidemiol. 2006;164(11):1094-102.
Tanaka H, Heiss G, McCabe EL, et al. "Hemodynamic Correlates of Blood Pressure in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." J Clin Hypertens (Greenwich). 2016;18(12):1222-1227.
Tanaka H, Palta P, Folsom AR, et al. "Habitual physical activity and central artery stiffening in older adults: the Atherosclerosis Risk in Communities study." J Hypertens. 2018;36(9):1889-1894.
Tamariz L, Agarwal S, Soliman EZ, et al. "Association of serum uric acid with incident atrial fibrillation (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2011;108(9):1272-6.
Tamariz LJ, Young HJ, Pankow JS, et al. "Blood viscosity and hematocrit as risk factors for type 2 diabetes mellitus: the atherosclerosis risk in communities (ARIC) study." Am J Epidemiol. 2008;168(10):1153-60.
Taliun D, Harris DN, Kessler MD, et al. "Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program." Nature. 2021;590(7845):290-299.
Takiar R, Lutsey PL, Zhao D, et al. "The associations of 25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms, and race with risk of incident fracture-related hospitalization: Twenty-year follow-up in a bi-ethnic cohort (the ARIC Study)." Bone. 2015;78:94-101.
Tajuddin SM, Schick UM, Eicher JD, et al. "Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases." Am J Hum Genet. 2016;99(1):22-39.
Tabor HK, Auer PL, Jamal SM, et al. "Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.
Szklo M, Cerhan J, Diez-Roux AV, et al. "Estrogen replacement therapy and cognitive functioning in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1996;144(11):1048-57.
Szklo M, Chambless LE, Folsom AR, et al. "Trends in plasma cholesterol levels in the atherosclerosis risk in communities (ARIC) study." Prev Med. 2000;30(3):252-9.
Syme C, Shin J, Richer L, Gaudet D, Fornage M, Paus T. "Epigenetic Loci of Blood Pressure." Circ Genom Precis Med. 2019;12(1):e002341.
Swerdlow DI, Preiss D, Kuchenbaecker KB, et al. "HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials." Lancet. 2015;385(9965):351-61.
Suzuki T, Agarwal SK, Deo R, et al. "Kidney function and sudden cardiac death in the community: The Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2016;180:46-53.
Suzuki T, Wang W, Wilsdon A, et al. "Carotid Intima-Media Thickness and the Risk of Sudden Cardiac Death: The ARIC Study and the CHS." J Am Heart Assoc. 2020;9(19):e016981.
Suri FMK, Zhou J, Qiao Y, et al. "Cognitive impairment and intracranial atherosclerotic stenosis in general population." Neurology. 2018;90(14):e1240-e1247.
Suri FMK, Yamagishi K, Aleksic N, Hannan PJ, Folsom AR. "Novel hemostatic factor levels and risk of ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study." Cerebrovasc Dis. 2010;29(5):497-502.
Suri MFareed K, Qiao Y, Ma X, et al. "Prevalence of Intracranial Atherosclerotic Stenosis Using High-Resolution Magnetic Resonance Angiography in the General Population: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(5):1187-93.
Surguchov AP, Boerwinkle E, Sharrett AR, Patsch W. "Effect of apolipoprotein E polymorphism on fasting retinyl palmitate level." Biochem Mol Med. 1995;55(2):156-7.
Surguchov AP, Boerwinkle E, Sharett AR, Patsch WP. "Apolipoprotein E genotype and lipid transport: insight into the role of the epsilon 4 allele." Atherosclerosis. 1994;106(1):119-21.
Surguchov AP, Page GP, Smith L, Patsch W, Boerwinkle E. "Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia." Arterioscler Thromb Vasc Biol. 1996;16(8):941-7.
Surendran P, Feofanova EV, Lahrouchi N, et al. "Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals." Nat Genet. 2020;52(12):1314-1332.