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ARIC Publications

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"Are There Clinical Implications of Racial Differences in HbA1c? A Difference, to Be a Difference, Must Make a Difference." Diabetes Care. 2016;39(8):1462-7.
Marioni RE, Yang J, Dykiert D, et al. "Assessing the genetic overlap between BMI and cognitive function." Mol Psychiatry. 2016;21(10):1477-82.
Rosenthal EA, Makaryan V, Burt AA, et al. "Association Between Absolute Neutrophil Count and Variation at TCIRG1: The NHLBI Exome Sequencing Project." Genet Epidemiol. 2016;40(6):470-4.
Srinath R, Gottesman RF, Golden SHill, Carson KA. "Association Between Endogenous Testosterone and Cerebrovascular Disease in the ARIC Study (Atherosclerosis Risk in Communities)." Stroke. 2016;47(11):2682-2688.
Tin A, Grams ME, Ashar FN, et al. "Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study." J Am Soc Nephrol. 2016;27(8):2467-73.
Selvin E, Rawlings A, Lutsey PL, Maruthur N, Pankow JS, Steffes M. "Association of 1,5-Anhydroglucitol With Cardiovascular Disease and Mortality." Diabetes. 2016;65(1):201-8.
Liang M, McEvoy JWilliam, Chen Y, Sharrett ARichey. "Association of a Biomarker of Glucose Peaks, 1,5-Anhydroglucitol, With Subclinical Cardiovascular Disease." Diabetes Care. 2016;39(10):1752-9.
Appiah D, Schreiner PJ, Demerath EW, Loehr LR, Chang PP. "Association of Age at Menopause With Incident Heart Failure: A Prospective Cohort Study and Meta-Analysis." J Am Heart Assoc. 2016;5(8).
Peloso GM, Lange LA, Varga TV, et al. "Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study." Circ Cardiovasc Genet. 2016;9(4):368-74.
Norby FL, Eryd SAdamsson, Niemeijer MN, et al. "Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium." PLoS One. 2016;11(3):e0151932.
Colantonio LD, Bittner V, Reynolds K, et al. "Association of Serum Lipids and Coronary Heart Disease in Contemporary Observational Studies." Circulation. 2016;133(3):256-64.
Kwon Y, Norby FL, Jensen PN, et al. "Association of Smoking, Alcohol, and Obesity with Cardiovascular Death and Ischemic Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study and Cardiovascular Health Study (CHS)." PLoS One. 2016;11(1):e0147065.
Fretz A, Schneider ALC, McEvoy JW, Hoogeveen RC, Ballantyne CM, Coresh JJ. "The Association of Socioeconomic Status With Subclinical Myocardial Damage, Incident Cardiovascular Events, and Mortality in the ARIC Study." Am J Epidemiol. 2016;183(5):452-61.
Willems SM, Cornes BK, Brody JA, et al. "Association of the IGF1 gene with fasting insulin levels." Eur J Hum Genet. 2016;24(9):1337-43.
Seaman CD, George KM, Ragni M. "Association of von Willebrand factor deficiency with prevalent cardiovascular disease and asymptomatic carotid atherosclerosis: The Atherosclerosis Risk in Communities Study." Thromb Res. 2016;144:236-8.
Yu B, Heiss G, Alexander D, Grams ME. "Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 2016;183(7):650-6.
Agarwala A, Virani S, Couper DJ, et al. "Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study." Atherosclerosis. 2016;253:156-163.
Rebholz CM, Grams ME, Lutsey PL, et al. "Biomarkers of Vitamin D Status and Risk of ESRD." Am J Kidney Dis. 2016;67(2):235-42.
Cushman M, O'Meara ES, Heckbert SR, Zakai NA, Rosamond WD. "Body size measures, hemostatic and inflammatory markers and risk of venous thrombosis: The Longitudinal Investigation of Thromboembolism Etiology." Thromb Res. 2016;144:127-32.
Di Angelantonio E, Bhupathiraju S, Wormser D, et al. "Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents." Lancet. 2016;388(10046):776-86.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Bundle branch blocks and the risk of mortality in the Atherosclerosis Risk in Communities study." J Cardiovasc Med (Hagerstown). 2016;17(6):411-7.
Luft VC, Duncan BB, Schmidt MI, et al. "Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case-cohort analysis of the ARIC Study." Diabet Med. 2016;33(10):1392-8.
Stevens J, Erber-Oakkar E, Cui Z, Cai J, Virani SS, Di Angelantonio E. "Cardiovascular disease risk by assigned treatment using the 2013 and 1998 obesity guidelines." Obesity (Silver Spring). 2016;24(7):1554-60.
Wong ND, Zhao Y, Patel R, et al. "Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study." Diabetes Care. 2016;39(5):668-76.
Bekwelem W, Jensen PN, Norby FL, et al. "Carotid Atherosclerosis and Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1643-6.
Chen LYee, Leening MJG, Norby FL, et al. "Carotid Intima-Media Thickness and Arterial Stiffness and the Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study, Multi-Ethnic Study of Atherosclerosis (MESA), and the Rotterdam Study." J Am Heart Assoc. 2016;5(5).
Pang Y, Sang Y, Ballew SH, Grams ME, Heiss G, Coresh JJ. "Carotid Intima-Media Thickness and Incident ESRD: The Atherosclerosis Risk in Communities (ARIC) Study." Clin J Am Soc Nephrol. 2016;11(7):1197-205.
Vu KN, Ballantyne CM, Hoogeveen RC, Nambi V, Volcik KA, Boerwinkle E. "Causal Role of Alcohol Consumption in an Improved Lipid Profile: The Atherosclerosis Risk in Communities (ARIC) Study." PLoS One. 2016;11(2):e0148765.
Cobb LK, McAdams-Demarco MA, Gudzune KA, et al. "Changes in Body Mass Index and Obesity Risk in Married Couples Over 25 Years: The ARIC Cohort Study." Am J Epidemiol. 2016;183(5):435-43.
Ishigami J, Grams ME, Naik RP, Coresh JJ. "Chronic Kidney Disease and Risk for Gastrointestinal Bleeding in the Community: The Atherosclerosis Risk in Communities (ARIC) Study." Clin J Am Soc Nephrol. 2016;11(10):1735-1743.
Prizment AE, Linabery AM, Lutsey PL, et al. "Circulating Beta-2 Microglobulin and Risk of Cancer: The Atherosclerosis Risk in Communities Study (ARIC)." Cancer Epidemiol Biomarkers Prev. 2016;25(4):657-64.
Meyer ML, Tanaka H, Palta P, Cheng S, Gouskova N, Aguilar D. "Correlates of Segmental Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(1):114-22.
van der Laan SW, Fall T, Soumaré A, et al. "Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study." J Am Coll Cardiol. 2016;68(9):934-45.
Rebholz CM, Crews DC, Grams ME, et al. "DASH (Dietary Approaches to Stop Hypertension) Diet and Risk of Subsequent Kidney Disease." Am J Kidney Dis. 2016;68(6):853-861.
Rubin J, Matsushita K, Lazo M, et al. "Determinants of minimal elevation in high-sensitivity cardiac troponin T in the general population." Clin Biochem. 2016;49(9):657-662.
Deo R, Norby FL, Katz R, et al. "Development and Validation of a Sudden Cardiac Death Prediction Model for the General Population." Circulation. 2016;134(11):806-16.
Fox ER, Samdarshi TE, Musani SK, et al. "Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort." JAMA Cardiol. 2016;1(1):15-25.
Schneider ALC, Kalyani RR, Golden S, et al. "Diabetes and Prediabetes and Risk of Hospitalization: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):772-9.
Khera AV, Won H-H, Peloso GM, et al. "Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia." J Am Coll Cardiol. 2016;67(22):2578-89.
McEvoy JW, Chen Y, Rawlings A, et al. "Diastolic Blood Pressure, Subclinical Myocardial Damage, and Cardiac Events: Implications for Blood Pressure Control." J Am Coll Cardiol. 2016;68(16):1713-1722.
Sahli MW, Mares JA, Meyers KJ, et al. "Dietary Intake of Lutein and Diabetic Retinopathy in the Atherosclerosis Risk in Communities Study (ARIC)." Ophthalmic Epidemiol. 2016;23(2):99-108.
J Smith G, Felix JF, Morrison AC, et al. "Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure." PLoS Genet. 2016;12(5):e1006034.
Konety S, Koene RJ, Norby FL, et al. "Echocardiographic Predictors of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study and Cardiovascular Health Study." Circ Cardiovasc Imaging. 2016;9(8).
O'Neal WT, Zhang Z-M, Loehr LR, Chen LYee, Alonso A. "Electrocardiographic Advanced Interatrial Block and Atrial Fibrillation Risk in the General Population." Am J Cardiol. 2016;117(11):1755-9.
O'Neal WT, Wang YGrace, Wu H-T, et al. "Electrocardiographic J Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2016;118(6):811-815.
Joehanes R, Just AC, Marioni RE, et al. "Epigenetic Signatures of Cigarette Smoking." Circ Cardiovasc Genet. 2016;9(5):436-447.
Rhee EP, Yang Q, Yu B, et al. "An exome array study of the plasma metabolome." Nat Commun. 2016;7:12360.
Rawlings AM, Bandeen-Roche K, Gross AL, et al. "Factor structure of the ARIC-NCS Neuropsychological Battery: An evaluation of invariance across vascular factors and demographic characteristics." Psychol Assess. 2016;28(12):1674-1683.
McKibben RA, Zhao D, Lutsey PL, Schneider ALC, Guallar E, Mosley TH. "Factors Associated With Change in 25-Hydroxyvitamin D Levels Over Longitudinal Follow-Up in the ARIC Study." J Clin Endocrinol Metab. 2016;101(1):33-43.
Joshi AD, Andersson C, Buch S, et al. "Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies." Gastroenterology. 2016;151(2):351-363.e28.
McEvoy JW, Chen Y, Halushka MK, et al. "Galectin-3 and Risk of Heart Failure and Death in Blacks and Whites." J Am Heart Assoc. 2016;5(5).
Tin A, Balakrishnan P, Beaty TH, Boerwinkle E, Hoogeveen RC, Young JH. "GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2016;33(7):968-75.
Lin H, Mueller-Nurasyid M, Smith AV, et al. "Gene-gene Interaction Analyses for Atrial Fibrillation." Sci Rep. 2016;6:35371.
Khera AV, Emdin CA, Drake I, et al. "Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease." N Engl J Med. 2016;375(24):2349-2358.
Guo D-C, Grove ML, Prakash SK, et al. "Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections." Am J Hum Genet. 2016;99(3):762-769.
Cheng Y-C, Stanne TM, Giese A-K, et al. "Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2." Stroke. 2016;47(2):307-16.
Teumer A, Tin A, Sorice R, et al. "Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes." Diabetes. 2016;65(3):803-17.
van Loon J, Dehghan A, Weihong T, et al. "Genome-wide association studies identify genetic loci for low von Willebrand factor levels." Eur J Hum Genet. 2016;24(7):1035-40.
Dehghan A, Bis JC, White CC, et al. "Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium." PLoS One. 2016;11(3):e0144997.
Keaton JM, Hellwege JN, C Y Ng M, et al. "Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans." PLoS One. 2016;11(7):e0159977.
Waks JW, Sitlani CM, Soliman EZ, et al. "Global Electric Heterogeneity Risk Score for Prediction of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies." Circulation. 2016;133(23):2222-34.
Burke BTeevan, Köttgen A, Law A, Grams M, Baer AN, Coresh JJ. "Gout in Older Adults: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2016;71(4):536-42.
Fyfe-Johnson AL, Muller CJ, Alonso A, et al. "Heart Rate Variability and Incident Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1452-8.
Schneider ALC, Jonassaint C, Sharrett ARichey, et al. "Hemoglobin, Anemia, and Cognitive Function: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2016;71(6):772-9.
Cowan LT, Alonso A, Pankow JS, Folsom AR, Rosamond WD, Gottesman RF. "Hospitalized Infection as a Trigger for Acute Ischemic Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1612-7.
"Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies." Lancet Neurol. 2016;15(7):695-707.
Kucharska-Newton AMaria, Heiss G, Ni H, Stearns SC, Puccinelli-Ortega N, Wruck LM. "Identification of Heart Failure Events in Medicare Claims: The Atherosclerosis Risk in Communities (ARIC) Study." J Card Fail. 2016;22(1):48-55.
Yazdani A, Yazdani A, Liu X. "Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis." Genet Epidemiol. 2016;40(6):486-91.
Begum F, Ruczinski I, Li S, et al. "Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort." Genet Epidemiol. 2016;40(1):81-8.
Ogunwale AN, Morrison AC, Sun W, et al. "The impact of multiple single day blood pressure readings on cardiovascular risk estimation: The Atherosclerosis Risk in Communities study." Eur J Prev Cardiol. 2016;23(14):1529-36.
Wu C, Demerath EW, Pankow JS, et al. "Imputation of missing covariate values in epigenome-wide analysis of DNA methylation data." Epigenetics. 2016;11(2):132-9.
Nadruz W, Gonçalves A, Claggett B, et al. "Influence of cigarette smoking on cardiac biomarkers: the Atherosclerosis Risk in Communities (ARIC) Study." Eur J Heart Fail. 2016;18(6):629-37.
X Androulakis M, Kodumuri N, Giamberardino LD, Rosamond WD, Gottesman RF, Yim E. "Ischemic stroke subtypes and migraine with visual aura in the ARIC study." Neurology. 2016;87(24):2527-2532.
Daya N, Voskertchian A, Schneider ALC, et al. "Kidney Function and Fracture Risk: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2016;67(2):218-226.
Suzuki T, Agarwal SK, Deo R, et al. "Kidney function and sudden cardiac death in the community: The Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2016;180:46-53.
Grams ME, Sang Y, Levey AS, et al. "Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate." N Engl J Med. 2016;374(5):411-21.
Gonçalves A, Hung C-L, Claggett B, et al. "Left Atrial Structure and Function Across the Spectrum of Cardiovascular Risk in the Elderly: The Atherosclerosis Risk in Communities Study." Circ Cardiovasc Imaging. 2016;9(2):e004010.
Power MC, Schneider ALC, Wruck L, et al. "Life-course blood pressure in relation to brain volumes." Alzheimers Dement. 2016;12(8):890-9.
Tang W, Yao L, Roetker NS, et al. "Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
Bell EJ, Lutsey PL, Basu S, Cushman M, Heckbert SR, Lloyd-Jones DM. "Lifetime Risk of Venous Thromboembolism in Two Cohort Studies." Am J Med. 2016;129(3):339.e19-26.