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ARIC Publications

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Bryant MJ, Stevens J, Truesdale KP, Mosley T, Chambless L. "Obesity and vital exhaustion: analysis of the Atherosclerosis Risk in the Communities study." Obesity (Silver Spring). 2008;16(7):1545-51.
Bidulescu A, Rose KM, Wolf SH, Rosamond WD. "Occupation recorded on certificates of death compared with self-report: the Atherosclerosis Risk in Communities (ARIC) Study." BMC Public Health. 2007;7:229.
Boland LL, Folsom AR, Sorlie PD, et al. "Occurrence of unrecognized myocardial infarction in subjects aged 45 to 65 years (the ARIC study)." Am J Cardiol. 2002;90(9):927-31.
Agarwal SK, Alonso A, Whelton SP, et al. "Orthostatic change in blood pressure and incidence of atrial fibrillation: results from a bi-ethnic population based study." PLoS One. 2013;8(11):e79030.
Rose KM, Couper D, Eigenbrodt ML, Mosley TH, A Sharrett R, Gottesman RF. "Orthostatic hypotension and cognitive function: the Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2010;34(1):1-7.
Franceschini N, Rose KM, Astor BC, Couper D, Vupputuri S. "Orthostatic hypotension and incident chronic kidney disease: the atherosclerosis risk in communities study." Hypertension. 2010;56(6):1054-9.
Eigenbrodt ML, Rose KM, Couper DJ, Arnett DK, Smith R, Jones D. "Orthostatic hypotension as a risk factor for stroke: the atherosclerosis risk in communities (ARIC) study, 1987-1996." Stroke. 2000;31(10):2307-13.
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Yao L, Folsom AR, Pankow JS, et al. "Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
Reis JP, Selvin E, Pankow JS, Michos ED, Rebholz CM. "Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
Tabor HK, Auer PL, Jamal SM, et al. "Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
Shahar E, Folsom AR, Romm FJ, et al. "Patterns of aspirin use in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 1996;131(5):915-22.
Michaud DS, Lu J, Peacock-Villada AY, et al. "Periodontal Disease Assessed Using Clinical Dental Measurements and Cancer Risk in the ARIC Study." J Natl Cancer Inst. 2018;110(8):843-854.
Kshirsagar AV, Moss KL, Elter JR, Beck JD, Offenbacher S, Falk RJ. "Periodontal disease is associated with renal insufficiency in the Atherosclerosis Risk In Communities (ARIC) study." Am J Kidney Dis. 2005;45(4):650-7.
Kalbaugh CA, Kucharska-Newton AMaria, Wruck L, et al. "Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2017;6(5).
Volcik KA, Nettleton JA, Ballantyne CM, Boerwinkle E. "Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2008;87(6):1926-31.
Pereira MA, Folsom AR, McGovern PG, et al. "Physical activity and incident hypertension in black and white adults: the Atherosclerosis Risk in Communities Study." Prev Med. 1999;28(3):304-12.
Chin K, Zhao D, Tibuakuu M, et al. "Physical Activity, Vitamin D, and Incident Atherosclerotic Cardiovascular Disease in Whites and Blacks: The ARIC Study." J Clin Endocrinol Metab. 2017;102(4):1227-1236.
Prizment AE, Folsom AR, Dreyfus J, et al. "Plasma C-reactive protein, genetic risk score, and risk of common cancers in the Atherosclerosis Risk in Communities study." Cancer Causes Control. 2013;24(12):2077-87.
Iso H, Folsom AR, Sato S, et al. "Plasma fibrinogen and its correlates in Japanese and US population samples." Arterioscler Thromb. 1993;13(6):783-90.
Brown SA, Hutchinson R, Morrisett J, et al. "Plasma lipid, lipoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb. 1993;13(8):1139-58.
Chen H, Mosley TH, Alonso A, Huang X. "Plasma urate and Parkinson's disease in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2009;169(9):1064-9.
Iso H, Harada S, Shimamoto T, et al. "Polymorphism of the apolipoprotein B gene and blood lipid concentrations in Japanese and Caucasian population samples." Atherosclerosis. 1996;126(2):233-41.
Zhou Z, Yu F, Buchanan A, et al. "Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts." PLoS One. 2014;9(1):e84810.
Dumitrescu L, Carty CL, Franceschini N, et al. "Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study." Ann Hum Genet. 2013;77(5):416-25.
Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM. "Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study." Hypertension. 2011;57(2):167-73.
West NA, Tingle JV, Simino J, Selvin E, Bressler J. "The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity." Alzheimer Dis Assoc Disord. 2018;32(2):131-136.
Morrison AC, Huang Z, Yu B, et al. "Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits." Am J Hum Genet. 2017;100(2):205-215.
Ibrahim-Verbaas CA, Fornage M, Bis JC, et al. "Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
Morrison AC, Bare LA, Chambless LE, et al. "Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2007;166(1):28-35.
Klein R, Clegg L, Cooper LS, et al. "Prevalence of age-related maculopathy in the Atherosclerosis Risk in Communities Study." Arch Ophthalmol. 1999;117(9):1203-10.
Parrinello CM, Rastegar I, Godino JG, Miedema MD, Matsushita K. "Prevalence of and Racial Disparities in Risk Factor Control in Older Adults With Diabetes: The Atherosclerosis Risk in Communities Study." Diabetes Care. 2015;38(7):1290-8.
Dong J, Pinto JM, Guo X, et al. "The Prevalence of Anosmia and Associated Factors Among U.S. Black and White Older Adults." J Gerontol A Biol Sci Med Sci. 2017;72(8):1080-1086.
Loehr LR, Soliman EZ, Poon AK, et al. "The prevalence of atrial fibrillation on 48-hour ambulatory electrocardiography in African Americans compared to Whites: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2019;216:1-8.
Simpson RJ, Cascio WE, Schreiner PJ, Crow RS, Rautaharju PM, Heiss G. "Prevalence of premature ventricular contractions in a population of African American and white men and women: the Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2002;143(3):535-40.
Garaas R, Moss KL, Fisher EL, et al. "Prevalence of visible third molars with caries experience or periodontal pathology in middle-aged and older Americans." J Oral Maxillofac Surg. 2011;69(2):463-70.
Smith JW, O'Neal WT, M Shoemaker B, Chen LYee, Alonso A, S Whalen P. "PR-Interval Components and Atrial Fibrillation Risk (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(3):466-472.
Shuldiner AR, Nguyen W, Kao WH, et al. "Pro115Gln peroxisome proliferator-activated receptor-gamma and obesity." Diabetes Care. 2000;23(1):126-7.
Kao LWH, Coresh J, Shuldiner AR, Boerwinkle E, Bray MS, Brancati FL. "Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 2003;52(6):1568-72.
Seidelmann SB, Vardeny O, Claggett B, et al. "An Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality." J Am Heart Assoc. 2017;6(4).
Folsom AR, Tang W, Roetker NS, Heckbert SR, Cushman M. "Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2015;90(11):1047-51.
Folsom AR, Szklo M, Stevens J, Liao F, Smith R, Eckfeldt JH. "A prospective study of coronary heart disease in relation to fasting insulin, glucose, and diabetes. The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 1997;20(6):935-42.
Folsom AR, Cushman M, Rasmussen-Torvik LJ, Heckbert SR, Tsai MY. "Prospective study of polymorphisms of the protein Z-dependent protease inhibitor and risk of venous thromboembolism." Thromb Haemost. 2007;97(3):493-4.
Folsom AR, Cushman M, Tsai MY, Heckbert SR, Aleksic N. "Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism." Am J Hematol. 2002;71(4):285-90.
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Schreiner PJ, Heiss G, Tyroler HA, Morrisett JD, Davis CE, Smith R. "Race and gender differences in the association of Lp(a) with carotid artery wall thickness. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb Vasc Biol. 1996;16(3):471-8.
Zhang Z-M, Rautaharju PM, Prineas RJ, et al. "Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(22):2141-8.
Rautaharju PM, Zhang Z-M, Haisty WK, et al. "Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2014;47(3):342-50.
Evans K, Coresh J, Bash LD, et al. "Race differences in access to health care and disparities in incident chronic kidney disease in the US." Nephrol Dial Transplant. 2011;26(3):899-908.
Reis JP, Michos ED, Selvin E, Pankow JS. "Race, vitamin D-binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2015;101(6):1232-40.
Fernandes-Silva MM, Shah AM, Hegde S, et al. "Race-Related Differences in Left Ventricular Structural and Functional Remodeling in Response to Increased Afterload: The ARIC Study." JACC Heart Fail. 2017;5(3):157-165.
Zakai NA, McClure LA, Judd SE, Safford MM, Folsom AR, Lutsey PL. "Racial and regional differences in venous thromboembolism in the United States in 3 cohorts." Circulation. 2014;129(14):1502-9.
Negi SI, Pankow JS, Fernstrom K, et al. "Racial differences in association of elevated interleukin-18 levels with type 2 diabetes: the Atherosclerosis Risk in Communities study." Diabetes Care. 2012;35(7):1513-8.
Magnani JW, Norby FL, Agarwal SK, Soliman EZ, Chen LYee, Loehr LR. "Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
Gupta DK, Claggett B, Wells Q, et al. "Racial differences in circulating natriuretic peptide levels: the atherosclerosis risk in communities study." J Am Heart Assoc. 2015;4(5).
Selvin E, Steffes MW, Ballantyne CM, Hoogeveen RC, Coresh J, Brancati FL. "Racial differences in glycemic markers: a cross-sectional analysis of community-based data." Ann Intern Med. 2011;154(5):303-9.
Maynard JW, McAdams-Demarco MA, Law A, Kao L, Gelber AC, Coresh JJ. "Racial differences in gout incidence in a population-based cohort: Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2014;179(5):576-83.
Naorungroj S, Slade GD, Divaris K, Heiss G, Offenbacher S. "Racial differences in periodontal disease and 10-year self-reported tooth loss among late middle-aged and older adults: the dental ARIC study." J Public Health Dent. 2017;77(4):372-382.
Qiao Y, Suri FK, Zhang Y, et al. "Racial Differences in Prevalence and Risk for Intracranial Atherosclerosis in a US Community-Based Population." JAMA Cardiol. 2017;2(12):1341-1348.
Hutchinson RG, Watson RL, Davis CE, et al. "Racial differences in risk factors for atherosclerosis. The ARIC Study. Atherosclerosis Risk in Communities." Angiology. 1997;48(4):279-90.
Zhao D, Post WS, Blasco-Colmenares E, et al. "Racial Differences in Sudden Cardiac Death." Circulation. 2019;139(14):1688-1697.
Lacy ME, Wellenius GA, Carnethon MR, et al. "Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study." Diabetes Care. 2016;39(2):285-91.
Wong T Y, Klein R, Duncan BB, et al. "Racial differences in the prevalence of hypertensive retinopathy." Hypertension. 2003;41(5):1086-91.
Williams JE, Massing M, Rosamond WD, Sorlie PD, Tyroler HA. "Racial disparities in CHD mortality from 1968-1992 in the state economic areas surrounding the ARIC study communities. Atherosclerosis Risk in Communities." Ann Epidemiol. 1999;9(8):472-80.
Nadruz W, Claggett B, Henglin M, et al. "Racial Disparities in Risks of Stroke." N Engl J Med. 2017;376(21):2089-2090.
Ding J, Diez Roux AV, Nieto JF, et al. "Racial disparity in long-term mortality rate after hospitalization for myocardial infarction: the Atherosclerosis Risk in Communities study." Am Heart J. 2003;146(3):459-64.
Kapoor A, Bakshy K, Xu L, et al. "Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
Lunetta KL, Day FR, Sulem P, et al. "Rare coding variants and X-linked loci associated with age at menarche." Nat Commun. 2015;6:7756.
Yu B, Pulit SL, Hwang S-J, et al. "Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk." Circ Cardiovasc Genet. 2016;9(1):64-70.
Olfson E, Saccone NL, Johnson EO, et al. "Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans." Mol Psychiatry. 2016;21(5):601-7.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Shah AM, Cheng S, Skali H, et al. "Rationale and design of a multicenter echocardiographic study to assess the relationship between cardiac structure and function and heart failure risk in a biracial cohort of community-dwelling elderly persons: the Atherosclerosis Risk in Communities stud." Circ Cardiovasc Imaging. 2014;7(1):173-81.
Folsom AR, Basu S, Hong C-P, Heckbert SR, Lutsey PL, Rosamond WD. "Reasons for Differences in the Incidence of Venous Thromboembolism in Black Versus White Americans." Am J Med. 2019;132(8):970-976.
Lalani SR, Liu P, Rosenfeld JA, et al. "Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations." Am J Hum Genet. 2016;98(2):347-57.
Reich D, Nalls MA, Kao LWH, et al. "Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene." PLoS Genet. 2009;5(1):e1000360.
Hardy ST, Loehr LR, Butler KR, et al. "Reducing the Blood Pressure-Related Burden of Cardiovascular Disease: Impact of Achievable Improvements in Blood Pressure Prevention and Control." J Am Heart Assoc. 2015;4(10):e002276.
Mahajan A, Wessel J, Willems SM, et al. "Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes." Nat Genet. 2018;50(4):559-571.
Tilling K, Lawlor DA, Smith GDavey, Chambless L, Szklo M. "The relation between components of adult height and intimal-medial thickness in middle age: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2006;164(2):136-42.

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