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ARIC Publications

2020
Bae SSharon, L Chang C, Merkin S S, Elashoff D, Ishigami J, Matsushita K. "Major Lipids and Future Risk of Pneumonia: 20-Year Observation of the Atherosclerosis Risk in Communities (ARIC) Study Cohort." Am J Med. 2020.
Maners J, Gill D, Pankratz N, et al. "A Mendelian randomization of γ' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke." Blood. 2020;136(26):3062-3069.
Justice AE, Chittoor G, Gondalia R, et al. "Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems." Epigenomics. 2020;12(17):1483-1499.
Koton S, Schneider ALC, B Windham G, Mosley TH, Gottesman RF. "Microvascular Brain Disease Progression and Risk of Stroke: The ARIC Study." Stroke. 2020;51(11):3264-3270.
Palta P, Heiss G, Sharrett ARichey, et al. "Mid- and Late-Life Leisure-Time Physical Activity and Global Brain Amyloid Burden: The Atherosclerosis Risk in Communities (ARIC)-PET Study." J Alzheimers Dis. 2020;76(1):139-147.
Teramoto K, Junior WNadruz, Matsushita K, et al. "Mid- to Late-Life Time-Averaged Cumulative Blood Pressure and Late-Life Cardiac Structure, Function, and Heart Failure." Hypertension. 2020;76(3):808-818.
George KM, Folsom AR, Sharrett ARichey, Mosley TH, Gottesman RF, Hamedani AG. "Migraine Headache and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." Headache. 2020;60(5):946-953.
DeBarmore B, Longchamps RJ, Zhang Y, et al. "Mitochondrial DNA copy number and diabetes: the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open Diabetes Res Care. 2020;8(1).
Zhao D, Bartz TM, Sotoodehnia N, et al. "Mitochondrial DNA copy number and incident atrial fibrillation." BMC Med. 2020;18(1):246.
Hong YSoo, Longchamps RJ, Zhao D, et al. "Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2020;141(22):1823-1825.
Castellani CA, Longchamps RJ, Sumpter JA, et al. "Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs." Genome Med. 2020;12(1):84.
Murthy VL, Yu B, Wang W, et al. "Molecular Signature of Multisystem Cardiometabolic Stress and Its Association With Prognosis." JAMA Cardiol. 2020.
Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Ntalla I, Weng L-C, Cartwright JH, et al. "Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction." Nat Commun. 2020;11(1):2542.
Baldassari AR, Sitlani CM, Highland HM, et al. "Multi-Ethnic Genome-Wide Association Study of Decomposed Cardioelectric Phenotypes Illustrates Strategies to Identify and Characterize Evidence of Shared Genetic Effects for Complex Traits." Circ Genom Precis Med. 2020;13(4):e002680.
Love S-AM, North KE, Zeng D, et al. "Nine-Year Ethanol Intake Trajectories and Their Association With 15-Year Cognitive Decline Among Black and White Adults." Am J Epidemiol. 2020;189(8):788-800.
George KM, Folsom AR, Norby FL. "No Association Found Between Midlife Seropositivity for Infection and Subsequent Cognitive Decline: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Geriatr Psychiatry Neurol. 2020;33(1):15-21.
Full KM, Jackson CL, Rebholz CM, Matsushita K. "Obstructive Sleep Apnea, Other Sleep Characteristics, and Risk of CKD in the Atherosclerosis Risk in Communities Sleep Heart Health Study." J Am Soc Nephrol. 2020;31(8):1859-1869.
Kim H, Rebholz CM, Garcia-Larsen V, Steffen LM, Coresh JJ. "Operational Differences in Plant-Based Diet Indices Affect the Ability to Detect Associations with Incident Hypertension in Middle-Aged US Adults." J Nutr. 2020;150(4):842-850.
Blum MF, Surapaneni A, Stewart JD, et al. "Particulate Matter and Albuminuria, Glomerular Filtration Rate, and Incident CKD." Clin J Am Soc Nephrol. 2020;15(3):311-319.
Tang O, Daya N, Matsushita K, et al. "Performance of High-Sensitivity Cardiac Troponin Assays to Reflect Comorbidity Burden and Improve Mortality Risk Stratification in Older Adults With Diabetes." Diabetes Care. 2020;43(6):1200-1208.
Demmer RT, Norby FL, Lakshminarayan K, et al. "Periodontal disease and incident dementia: The Atherosclerosis Risk in Communities Study (ARIC)." Neurology. 2020;95(12):e1660-e1671.
Beck JD, Philips K, Moss K, Sen S, Morelli T, Preisser J. "Periodontal disease classifications and incident coronary heart disease in the Atherosclerosis Risk in Communities study." J Periodontol. 2020;91(11):1409-1418.
Florido R, Kwak L, Lazo M, et al. "Physical Activity and Incident Heart Failure in High-Risk Subgroups: The ARIC Study." J Am Heart Assoc. 2020;9(10):e014885.
Jia X, Sun C, Tang O, et al. "Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women." J Clin Endocrinol Metab. 2020;105(12).
Li D, Misialek JR, Jing M, et al. "Plasma phospholipid very-long-chain SFAs in midlife and 20-year cognitive change in the Atherosclerosis Risk in Communities (ARIC): a cohort study." Am J Clin Nutr. 2020;111(6):1252-1258.
Jaspers NEM, Blaha MJ, Matsushita K, et al. "Prediction of individualized lifetime benefit from cholesterol lowering, blood pressure lowering, antithrombotic therapy, and smoking cessation in apparently healthy people." Eur Heart J. 2020;41(11):1190-1199.
Sharma K, Mok Y, Kwak L, et al. "Predictors of Mortality by Sex and Race in Heart Failure With Preserved Ejection Fraction: ARIC Community Surveillance Study." J Am Heart Assoc. 2020;9(19):e014669.
Arora S, Sivaraj K, Hendrickson M, et al. "Prevalence and Prognostic Significance of Mitral Regurgitation in Acute Decompensated Heart Failure: The ARIC Study." JACC Heart Fail. 2020.
Fang M, Wang D, Tang O, Selvin E. "Prevalence of Chronic Disease in Laboratory-Confirmed COVID-19 Cases and U.S. Adults (2017-2018)." Diabetes Care. 2020;43(10):e127-e128.
Teramoto K, Santos M, Claggett B, et al. "Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis." PLoS Med. 2020;17(10):e1003361.
Hicks CW, Daya NR, Black JH, Matsushita K. "Race and sex-based disparities associated with carotid endarterectomy in the Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2020;292:10-16.
Chen TK, Coresh JJ, Daya N, Ballew SH, Tin A, Crews DC. "Race, APOL1 Risk Variants, and Clinical Outcomes among Older Adults: The ARIC Study." J Am Geriatr Soc. 2020.
Lewis AA, Ayers CR, Selvin E, et al. "Racial Differences in Malignant Left Ventricular Hypertrophy and Incidence of Heart Failure: A Multicohort Study." Circulation. 2020;141(12):957-967.
Sadler B, Haller G, Antunes L, et al. "Rare and duplications containing in clubfoot." J Med Genet. 2020;57(12):851-857.
Chunawala Z, Chang PP, DeFilippis AP, Hall ME, Matsushita K, Caughey MC. "Recurrent Admissions for Acute Decompensated Heart Failure Among Patients With and Without Peripheral Artery Disease: The ARIC Study." J Am Heart Assoc. 2020;9(21):e017174.
Gellert KS, Keil AP, Zeng D, et al. "Reducing the Population Burden of Coronary Heart Disease by Modifying Adiposity: Estimates From the ARIC Study." J Am Heart Assoc. 2020;9(4):e012214.
Deal JA, Power MC, Palta P, et al. "Relationship of Cigarette Smoking and Time of Quitting with Incident Dementia and Cognitive Decline." J Am Geriatr Soc. 2020;68(2):337-345.
Tang W, Saratzis A, Pattee J, et al. "Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG." Eur J Vasc Endovasc Surg. 2020;59(1):92-97.
Folsom AR, Lutsey PL, Pope ZC, Fashanu OE, Misialek JR, Cushman M. "Resting heart rate and incidence of venous thromboembolism." Res Pract Thromb Haemost. 2020;4(2):238-246.
Yang C, Kwak L, Ballew SH, et al. "Retinal microvascular findings and risk of incident peripheral artery disease: An analysis from the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2020;294:62-71.
Surapaneni AL, Ballew SH, Coresh JJ, Ballantyne CM, Selvin E, Matsushita K. " Risk Alleles, Cardiac Markers, and Risk of ESKD in African Americans: The Atherosclerosis Risk in Communities Study." Kidney Med. 2020;2(4):502-504.
DeBoer MD, Filipp SL, Sims M, Musani SK. "Risk of Ischemic Stroke Increases Over the Spectrum of Metabolic Syndrome Severity." Stroke. 2020;51(8):2548-2552.
Lee AK, Woodward M, Wang D, et al. "The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE." J Clin Endocrinol Metab. 2020;105(1).
Wang Z, Chen H, Bartz TM, et al. "Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels." Circ Genom Precis Med. 2020;13(4):e002772.
Rooney MR, Lutsey PL, Alonso A, et al. "Serum magnesium and burden of atrial and ventricular arrhythmias: The Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2020;62:20-25.
Rooney MR, Alonso A, Folsom AR, et al. "Serum magnesium and the incidence of coronary artery disease over a median 27 years of follow-up in the Atherosclerosis Risk in Communities (ARIC) Study and a meta-analysis." Am J Clin Nutr. 2020;111(1):52-60.
Menez S, Ding N, Grams ME, et al. "Serum magnesium, bone-mineral metabolism markers and their interactions with kidney function on subsequent risk of peripheral artery disease: the Atherosclerosis Risk in Communities Study." Nephrol Dial Transplant. 2020;35(11):1878-1885.
Menni C, Zhu J, Le Roy CI, et al. "Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes." Gut Microbes. 2020;11(6):1632-1642.
Chen G-C, Chai JChoul, Yu B, et al. "Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)." Am J Clin Nutr. 2020;112(1):57-65.
Lee AK, Juraschek SP, B Windham G, Lee CJ, Sharrett ARichey, Coresh JJ. "Severe Hypoglycemia and Risk of Falls in Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2020;43(9):2060-2065.
Echouffo-Tcheugui JB, Daya N, Lee AK, et al. "Severe Hypoglycemia, Cardiac Structure and Function, and Risk of Cardiovascular Events Among Older Adults With Diabetes." Diabetes Care. 2020.
Zhao D, Guallar E, Ballantyne CM, et al. "Sex Hormones and Incident Heart Failure in Men and Postmenopausal Women: The Atherosclerosis Risk in Communities Study." J Clin Endocrinol Metab. 2020;105(10).
Meyer ML, Soliman EZ, Drager D. "Short-term repeatability of electrocardiographic criteria of left ventricular hypertrophy." Ann Noninvasive Electrocardiol. 2020;25(2):e12688.
Lu Y, Tang O, Brady TM, et al. "Simplified blood pressure measurement approaches and implications for hypertension screening: the Atherosclerosis Risk in Communities study." J Hypertens. 2020.
Zheng Z, Rebholz CM, Matsushita K, et al. "Survival advantage of cohort participation attenuates over time: results from three long-standing community-based studies." Ann Epidemiol. 2020;45:40-46.e4.
Pandey A, Vaduganathan M, Arora S, et al. "Temporal Trends in Prevalence and Prognostic Implications of Comorbidities Among Patients With Acute Decompensated Heart Failure: The ARIC Study Community Surveillance." Circulation. 2020;142(3):230-243.
Quispe R, Elshazly MB, Zhao D, et al. "Total cholesterol/HDL-cholesterol ratio discordance with LDL-cholesterol and non-HDL-cholesterol and incidence of atherosclerotic cardiovascular disease in primary prevention: The ARIC study." Eur J Prev Cardiol. 2020;27(15):1597-1605.
Koton S, Sang Y, Schneider ALC, Rosamond WD, Gottesman RF. "Trends in Stroke Incidence Rates in Older US Adults: An Update From the Atherosclerosis Risk in Communities (ARIC) Cohort Study." JAMA Neurol. 2020;77(1):109-113.
Cowan LT, Buck B, Schwind JS, et al. "Triggering of cardiovascular disease by infection type: The atherosclerosis risk in communities study (ARIC)." Int J Cardiol. 2020.
Sekula P, Tin A, Schultheiss UT, et al. "Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease." Sci Rep. 2020;10(1):10018.
Luo S, Surapaneni A, Zheng Z, et al. "Variants, N-Acetylated Amino Acids, and Progression of CKD." Clin J Am Soc Nephrol. 2020;16(1):37-47.
French SA, Lutsey PL, Rosamond WD, Maclehose RF, Cushman M. "Weight change over 9 years and subsequent risk of venous thromboembolism in the ARIC cohort." Int J Obes (Lond). 2020;44(12):2465-2471.
Ma J, Rebholz CM, Braun KVE, et al. "Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality." Circ Genom Precis Med. 2020;13(4):e002766.
Bis JC, Jian X, Kunkle BW, et al. "Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation." Mol Psychiatry. 2020;25(8):1859-1875.
2019
Liu Y, Chen S, Li Z, Morrison AC, Boerwinkle E. "ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies." Am J Hum Genet. 2019;104(3):410-421.
Chang AR, Grams ME, Ballew SH, et al. "Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium." BMJ. 2019;364:k5301.
Oelsner EC, Balte PP, Grams ME, et al. "Albuminuria, Lung Function Decline, and Risk of Incident Chronic Obstructive Pulmonary Disease. The NHLBI Pooled Cohorts Study." Am J Respir Crit Care Med. 2019;199(3):321-332.
He X, Rebholz CM, Daya N, Lazo M. "Alcohol consumption and incident diabetes: The Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2019;62(5):770-778.
Ma Y, Jun GR, Zhang X, et al. "Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype." JAMA Neurol. 2019.
Pokharel Y, Mouhanna F, Nambi V, et al. "ApoB, small-dense LDL-C, Lp(a), LpPLA activity, and cognitive change." Neurology. 2019;92(22):e2580-e2593.
Hurwitz LM, Joshu CE, Barber JR, et al. "Aspirin and Non-Aspirin NSAID Use and Prostate Cancer Incidence, Mortality, and Case Fatality in the Atherosclerosis Risk in Communities Study." Cancer Epidemiol Biomarkers Prev. 2019;28(3):563-569.
Ellervik C, Roselli C, Christophersen IE, et al. "Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study." JAMA Cardiol. 2019;4(2):144-152.
Rattani A, Claxton J'NS, Ali MK, Chen LYee, Soliman EZ. "Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in The Atherosclerosis Risk in Communities study." BMC Cardiovasc Disord. 2019;19(1):262.
Myhre PL, Claggett B, Ballantyne CM, et al. "Association Between Circulating Troponin Concentrations, Left Ventricular Systolic and Diastolic Functions, and Incident Heart Failure in Older Adults." JAMA Cardiol. 2019;4(10):997-1006.
Onyeaghala G, Lutsey PL, Demerath EW, Folsom AR, Joshu CE, Platz EA. "Association between greater leg length and increased incidence of colorectal cancer: the atherosclerosis risk in communities (ARIC) study." Cancer Causes Control. 2019;30(8):791-797.
Yu Z, Rebholz CM, Wong E, Chen Y, Matsushita K, Coresh JJ. "Association Between Hypertension and Kidney Function Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2019;74(3):310-319.
Oliver-Williams C, Vladutiu CJ, Loehr LR, Rosamond WD. "The Association Between Parity and Subsequent Cardiovascular Disease in Women: The Atherosclerosis Risk in Communities Study." J Womens Health (Larchmt). 2019;28(5):721-727.
George KM, Lutsey PL, Selvin E, Palta P, Windham BGwen. "Association Between Thyroid Dysfunction and Incident Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." J Endocrinol Metab. 2019;9(4):82-89.
Johnson EL, Krauss GL, Lee AK, et al. "Association between white matter hyperintensities, cortical volumes, and late-onset epilepsy." Neurology. 2019;92(9):e988-e995.

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