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ARIC Publications

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Rodriguez S, Gaunt TR, Guo Y, et al. "Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array." Eur J Hum Genet. 2016;24(1):106-12.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Petruski-Ivleva N, Viera AJ, Shimbo D, et al. "Longitudinal Patterns of Change in Systolic Blood Pressure and Incidence of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." Hypertension. 2016;67(6):1150-6.
Yu B, Li AH, Metcalf GA, et al. "Loss-of-function variants influence the human serum metabolome." Sci Adv. 2016;2(8):e1600800.
Maheshwari A, Norby FL, Soliman EZ, Adabag S, Whitsel EA, Alonso A. "Low Heart Rate Variability in a 2-Minute Electrocardiogram Recording Is Associated with an Increased Risk of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(8):e0161648.
Mirabelli MC, Preisser JS, Loehr LR, et al. "Lung function decline over 25 years of follow-up among black and white adults in the ARIC study cohort." Respir Med. 2016;113:57-64.
Kubota Y, London SJ, Cushman M, et al. "Lung function, respiratory symptoms and venous thromboembolism risk: the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2016;14(12):2394-2401.
de Vries PS, Chasman DI, Sabater-Lleal M, et al. "A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration." Hum Mol Genet. 2016;25(2):358-70.
van Leeuwen EM, Sabo A, Bis JC, et al. "Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels." J Med Genet. 2016;53(7):441-9.
Hill WD, Davies G, Harris SE, et al. "Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions." Transl Psychiatry. 2016;6(12):e980.
Gori M, Gupta DK, Claggett B, et al. "Natriuretic Peptide and High-Sensitivity Troponin for Cardiovascular Risk Prediction in Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):677-85.
Willeit P, Kaptoge S, Welsh P, et al. "Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis." Lancet Diabetes Endocrinol. 2016;4(10):840-9.
Jensen RA, Sim X, Smith A V, et al. "Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
Ndumele CE, Matsushita K, Sang Y, et al. "N-Terminal Pro-Brain Natriuretic Peptide and Heart Failure Risk Among Individuals With and Without Obesity: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(7):631-8.
Ndumele CE, Matsushita K, Lazo M, et al. "Obesity and Subtypes of Incident Cardiovascular Disease." J Am Heart Assoc. 2016;5(8).
Lutsey PL, Bengtson LGS, Punjabi NM, et al. "Obstructive Sleep Apnea and 15-Year Cognitive Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Sleep. 2016;39(2):309-16.
Nagayoshi M, Punjabi NM, Selvin E, et al. "Obstructive sleep apnea and incident type 2 diabetes." Sleep Med. 2016;25:156-161.
Bell EJ, Agarwal SK, Cushman M, Heckbert SR, Lutsey PL. "Orthostatic Hypotension and Risk of Venous Thromboembolism in 2 Cohort Studies." Am J Hypertens. 2016;29(5):634-40.
Korada SKrishna C, Zhao D, Gottesman RF, et al. "Parathyroid Hormone and Subclinical Cerebrovascular Disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study." J Stroke Cerebrovasc Dis. 2016;25(4):883-93.
Yao L, Folsom AR, Pankow JS, et al. "Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
Reis JP, Selvin E, Pankow JS, Michos ED, Rebholz CM. "Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
Naimark DMJ, Grams ME, Matsushita K, et al. "Past Decline Versus Current eGFR and Subsequent Mortality Risk." J Am Soc Nephrol. 2016;27(8):2456-66.
Florido R, Zhao D, Ndumele CE, et al. "Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2016;5(9).
Folsom AR, Gottesman RF, Appiah D, Shahar E. "Plasma d-Dimer and Incident Ischemic Stroke and Coronary Heart Disease: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(1):18-23.
Dearborn JL, Qiao Y, Guallar E, Steffen LM, Gottesman RF, Zhang Y. "Polyunsaturated fats, carbohydrates and carotid disease: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI study." Atherosclerosis. 2016;251:361-366.
Campbell W, Ganna A, Ingelsson E. "Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models." J Clin Epidemiol. 2016;69:89-95.
Santos ABS, Gupta DK, Bello NA, et al. "Prehypertension is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study." Am J Hypertens. 2016;29(5):568-74.
Santos M, Kitzman DW, Matsushita K, Loehr LR, Sueta CA. "Prognostic Importance of Dyspnea for Cardiovascular Outcomes and Mortality in Persons without Prevalent Cardiopulmonary Disease: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(10):e0165111.
Gurka MJ, Vishnu A, Santen RJ. "Progression of Metabolic Syndrome Severity During the Menopausal Transition." J Am Heart Assoc. 2016;5(8).
Folsom AR, Tang W, George KM, Heckbert SR, Maclehose RF, Cushman M. "Prospective study of γ' fibrinogen and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Thromb Res. 2016;139:44-9.
Lazarus B, Chen Y, Wilson FP, Sang Y, Chang AR, Coresh JJ. "Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease." JAMA Intern Med. 2016;176(2):238-46.
Beyhaghi H, Reeve BB, Rodgers JE. "Psychometric Properties of the Four-Item Morisky Green Levine Medication Adherence Scale among Atherosclerosis Risk in Communities (ARIC) Study Participants." Value Health. 2016;19(8):996-1001.
Zhang Z-M, Rautaharju PM, Prineas RJ, et al. "Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(22):2141-8.
Parrinello CM, Sharrett ARichey, Maruthur NM, Bergenstal RM, Grams ME, Coresh JJ. "Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia." Diabetes Care. 2016;39(4):589-95.
Magnani JW, Norby FL, Agarwal SK, Soliman EZ, Chen LYee, Loehr LR. "Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
Lacy ME, Wellenius GA, Carnethon MR, et al. "Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study." Diabetes Care. 2016;39(2):285-91.
Kapoor A, Bakshy K, Xu L, et al. "Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
Olfson E, Saccone NL, Johnson EO, et al. "Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans." Mol Psychiatry. 2016;21(5):601-7.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Zanoni P, Khetarpal SA, Larach DB, et al. "Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease." Science. 2016;351(6278):1166-71.
Waikar SS, Sabbisetti V, rnlöv JÄ, et al. "Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies." Nephrol Dial Transplant. 2016;31(9):1460-70.
Rebholz CM, Anderson CAM, Grams ME, et al. "Relationship of the American Heart Association's Impact Goals (Life's Simple 7) With Risk of Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Cohort Study." J Am Heart Assoc. 2016;5(4):e003192.
Folsom AR, Tang W, Weng L-C, Roetker NS, Cushman M, Basu S. "Replication of a genetic risk score for venous thromboembolism in whites but not in African Americans." J Thromb Haemost. 2016;14(1):83-8.
Lubin JH, Couper DJ, Lutsey PL, Woodward M, Yatsuya H. "Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
Parrinello CM, Matsushita K, Woodward M, Wagenknecht LE, Coresh JJ. "Risk prediction of major complications in individuals with diabetes: the Atherosclerosis Risk in Communities Study." Diabetes Obes Metab. 2016;18(9):899-906.
Alonso A, Misialek JR, Michos ED, et al. "Serum 25-hydroxyvitamin D and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Europace. 2016;18(8):1143-9.
Shrestha S, Lutsey PL, Alonso A, Huang X, Mosley TH. "Serum 25-hydroxyvitamin D concentrations in Mid-adulthood and Parkinson's disease risk." Mov Disord. 2016;31(7):972-8.
Rooney MR, Pankow JS, Sibley SD, Selvin E, Reis JP, Michos ED. "Serum calcium and incident type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Am J Clin Nutr. 2016;104(4):1023-1029.
Fyfe-Johnson AL, Alonso A, Selvin E, Bower JK, Pankow JS, Agarwal SK. "Serum fibroblast growth factor-23 and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) Study." J Hypertens. 2016;34(7):1266-72.
Chen Y, Chang AR, McAdams DeMarco MA, et al. "Serum Potassium, Mortality, and Kidney Outcomes in the Atherosclerosis Risk in Communities Study." Mayo Clin Proc. 2016;91(10):1403-1412.
Kubota Y, McAdams-DeMarco M. "Serum uric acid, gout, and venous thromboembolism: The atherosclerosis risk in communities study." Thromb Res. 2016;144:144-8.
Lutsey PL, Parrinello CM, Misialek JR, et al. "Short-term Variability of Vitamin D-Related Biomarkers." Clin Chem. 2016;62(12):1647-1653.
McEvoy JW, Chen Y, Ndumele CE, et al. "Six-Year Change in High-Sensitivity Cardiac Troponin T and Risk of Subsequent Coronary Heart Disease, Heart Failure, and Death." JAMA Cardiol. 2016;1(5):519-28.
Lutsey PL, Norby FL, Gottesman RF, et al. "Sleep Apnea, Sleep Duration and Brain MRI Markers of Cerebral Vascular Disease and Alzheimer's Disease: The Atherosclerosis Risk in Communities Study (ARIC)." PLoS One. 2016;11(7):e0158758.
Nadruz W, Claggett B, Gonçalves A, et al. "Smoking and Cardiac Structure and Function in the Elderly: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Cardiovasc Imaging. 2016;9(9):e004950.
Kats D, Patel MD, Palta P, et al. "Social support and cognition in a community-based cohort: the Atherosclerosis Risk in Communities (ARIC) study." Age Ageing. 2016;45(4):475-80.
Cobb LK, Godino JG, Selvin E, Kucharska-Newton AMaria, Coresh JJ. "Spousal Influence on Physical Activity in Middle-Aged and Older Adults: The ARIC Study." Am J Epidemiol. 2016;183(5):444-51.
Agarwal SK, Wruck L, Quibrera M, et al. "Temporal Trends in Hospitalization for Acute Decompensated Heart Failure in the United States, 1998-2011." Am J Epidemiol. 2016;183(5):462-70.
Norby FL, Soliman EZ, Chen LYee, Bengtson LGS, Loehr LR, Agarwal SK. "Trajectories of Cardiovascular Risk Factors and Incidence of Atrial Fibrillation Over a 25-Year Follow-Up: The ARIC Study (Atherosclerosis Risk in Communities)." Circulation. 2016;134(8):599-610.
Lubitz SA, Brody JA, Bihlmeyer NA, et al. "Whole Exome Sequencing in Atrial Fibrillation." PLoS Genet. 2016;12(9):e1006284.
Yu B, de Vries PS, Metcalf GA, et al. "Whole genome sequence analysis of serum amino acid levels." Genome Biol. 2016;17(1):237.
Farlow JL, Robak LA, Hetrick K, et al. "Whole-Exome Sequencing in Familial Parkinson Disease." JAMA Neurol. 2016;73(1):68-75.
Michos ED, Misialek JR, Selvin E, Folsom AR, Pankow JS, Post WS. "25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms and incident coronary heart disease among whites and blacks: The ARIC study." Atherosclerosis. 2015;241(1):12-7.
Lutsey PL, Eckfeldt JH, Ogagarue ER, Folsom AR, Michos ED. "The 25-hydroxyvitamin D3 C-3 epimer: distribution, correlates, and reclassification of 25-hydroxyvitamin D status in the population-based Atherosclerosis Risk in Communities Study (ARIC)." Clin Chim Acta. 2015;442:75-81.
Tandon A, Chen CJ, Penman A, et al. "African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans." Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005.
Gonçalves A, Claggett B, Jhund PS, et al. "Alcohol consumption and risk of heart failure: the Atherosclerosis Risk in Communities Study." Eur Heart J. 2015;36(15):939-45.
Folsom AR, Olson NC, Lutsey PL, Roetker NS. "American Heart Association's Life's Simple 7 and incidence of venous thromboembolism." Am J Hematol. 2015;90(5):E92.
Folsom AR, Shah AM, Lutsey PL, et al. "American Heart Association's Life's Simple 7: Avoiding Heart Failure and Preserving Cardiac Structure and Function." Am J Med. 2015;128(9):970-6.e2.
C Quarta C, Buxbaum JN, Shah AM, et al. "The amyloidogenic V122I transthyretin variant in elderly black Americans." N Engl J Med. 2015;372(1):21-9.
Gross AL, Power MC, Albert MS, et al. "Application of Latent Variable Methods to the Study of Cognitive Decline When Tests Change over Time." Epidemiology. 2015;26(6):878-87.
Corrales-Medina VF, Alvarez KN, Weissfeld LA, et al. "Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease." JAMA. 2015;313(3):264-74.
Grubbs V, Vittinghoff E, Beck JD, et al. "Association Between Periodontal Disease and Kidney Function Decline in African Americans: The Jackson Heart Study." J Periodontol. 2015;86(10):1126-32.
Di Angelantonio E, Kaptoge S, Wormser D, et al. "Association of Cardiometabolic Multimorbidity With Mortality." JAMA. 2015;314(1):52-60.
Haring B, Misialek JR, Rebholz CM, Petruski-Ivleva N, Gottesman RF, Mosley TH. "Association of Dietary Protein Consumption With Incident Silent Cerebral Infarcts and Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 2015;46(12):3443-50.
Kim Y, Matsushita K, Sang Y, et al. "Association of high-sensitivity cardiac troponin T and natriuretic peptide with incident ESRD: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(4):550-8.
Brown CH, Sharrett ARichey, Coresh JJ, et al. "Association of hospitalization with long-term cognitive and brain MRI changes in the ARIC cohort." Neurology. 2015;84(14):1443-53.
Huang M, Matsushita K, Sang Y, Ballew SH, Astor BC. "Association of kidney function and albuminuria with prevalent and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(1):58-66.
Lazo M, Rubin J, Clark JM, et al. "The association of liver enzymes with biomarkers of subclinical myocardial damage and structural heart disease." J Hepatol. 2015;62(4):841-7.
Rebholz CM, Astor BC, Grams ME, et al. "Association of plasma levels of soluble receptor for advanced glycation end products and risk of kidney disease: the Atherosclerosis Risk in Communities study." Nephrol Dial Transplant. 2015;30(1):77-83.
Appiah D, Schreiner PJ, Maclehose RF. "Association of Plasma γ' Fibrinogen With Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb Vasc Biol. 2015;35(12):2700-6.