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ARIC Publications

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Cohen JC, Boerwinkle E, Mosley TH, Hobbs HH. "Sequence variations in PCSK9, low LDL, and protection against coronary heart disease." N Engl J Med. 2006;354(12):1264-72.
Chu AY, Coresh J, Arking DE, et al. "NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2010;53(3):510-6.
Christophersen IE, Rienstra M, Roselli C, et al. "Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation." Nat Genet. 2017;49(6):946-952.
Chin K, Zhao D, Tibuakuu M, et al. "Physical Activity, Vitamin D, and Incident Atherosclerotic Cardiovascular Disease in Whites and Blacks: The ARIC Study." J Clin Endocrinol Metab. 2017;102(4):1227-1236.
Chichlowska KL, Rose KM, Diez-Roux AV, Golden SH, McNeill AM, Heiss G. "Life course socioeconomic conditions and metabolic syndrome in adults: the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 2009;19(12):875-83.
Cheung N, Shankar A, Klein R, Folsom AR, Couper DJ, Wong T Y. "Age-related macular degeneration and cancer mortality in the atherosclerosis risk in communities study." Arch Ophthalmol. 2007;125(9):1241-7.
Cheng C-Y, Reich D, Coresh J, et al. "Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study." Obesity (Silver Spring). 2010;18(3):563-72.
Cheng C-Y, Reich D, Haiman CA, et al. "African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts." PLoS One. 2012;7(3):e32840.
Cheng Y-C, Stanne TM, Giese A-K, et al. "Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2." Stroke. 2016;47(2):307-16.
Cheng S, Claggett B, Correia AW, et al. "Temporal trends in the population attributable risk for cardiovascular disease: the Atherosclerosis Risk in Communities Study." Circulation. 2014;130(10):820-8.
Chen H, Mosley TH, Alonso A, Huang X. "Plasma urate and Parkinson's disease in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2009;169(9):1064-9.
Chen Z, Tang H, Qayyum R, et al. "Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network." Hum Mol Genet. 2013;22(12):2529-38.
Chen CTL, Liu C-T, Chen GK, et al. "Meta-analysis of loci associated with age at natural menopause in African-American women." Hum Mol Genet. 2014;23(12):3327-42.
Chen J, Spracklen CN, Marenne G, et al. "The trans-ancestral genomic architecture of glycemic traits." Nat Genet. 2021;53(6):840-860.
Chatterjee R, Yeh H-C, Shafi T, et al. "Serum potassium and the racial disparity in diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2011;93(5):1087-91.
Chatterjee R, Davenport CA, Raffield LM, et al. "KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts." PLoS One. 2018;13(8):e0203213.
Chatterjee R, Brancati FL, Shafi T, et al. "Non-traditional risk factors are important contributors to the racial disparity in diabetes risk: the atherosclerosis risk in communities study." J Gen Intern Med. 2014;29(2):290-7.
Chang PP, Wruck LM, Shahar E, et al. "Trends in Hospitalizations and Survival of Acute Decompensated Heart Failure in Four US Communities (2005-2014): ARIC Study Community Surveillance." Circulation. 2018;138(1):12-24.
Chamberlain AM, Agarwal SK, Ambrose M, Folsom AR, Soliman EZ, Alonso A. "Metabolic syndrome and incidence of atrial fibrillation among blacks and whites in the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2010;159(5):850-6.
Chamberlain AM, Schabath MB, Folsom AR. "Associations of chronic obstructive pulmonary disease with all-cause mortality in Blacks and Whites: the atherosclerosis risk in communities (ARIC) study." Ethn Dis. 2009;19(3):308-14.
Caughey MC, Qiao Y, Windham BGwen, Gottesman RF, Mosley TH. "Carotid Intima-Media Thickness and Silent Brain Infarctions in a Biracial Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2018;31(8):869-875.
Catellier DJ, Aleksic N, Folsom AR, Boerwinkle E. "Atherosclerosis Risk in Communities (ARIC) Carotid MRI flow cytometry study of monocyte and platelet markers: intraindividual variability and reliability." Clin Chem. 2008;54(8):1363-71.
Carty CL, Bůžková P, Fornage M, et al. "Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study." Circ Cardiovasc Genet. 2012;5(2):210-6.
Carnethon MR, Palaniappan LP, Burchfiel CM, Brancati FL, Fortmann SP. "Serum insulin, obesity, and the incidence of type 2 diabetes in black and white adults: the atherosclerosis risk in communities study: 1987-1998." Diabetes Care. 2002;25(8):1358-64.
Carlson CS, Matise TC, North KE, et al. "Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study." PLoS Biol. 2013;11(9):e1001661.
Campos M, Buchanan A, Yu F, et al. "Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study." Blood. 2012;119(8):1929-34.
Cakir B, Pankow JS, Salomaa V, et al. "Distribution of Lewis (FUT3)genotype and allele: frequencies in a biethnic United States population." Ann Hematol. 2002;81(10):558-65.
C Y Ng M, Graff M, Lu Y, et al. "Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium." PLoS Genet. 2017;13(4):e1006719.
Butler KR, Penman AD, Minor DS. "Determinants of pulse pressure and annual rates of change in the Atherosclerosis Risk in Communities study." J Hypertens. 2015;33(12):2463-70.
Burke GL, Evans GW, Riley WA, et al. "Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 1995;26(3):386-91.
Bryant MJ, Stevens J, Truesdale KP, Mosley T, Chambless L. "Obesity and vital exhaustion: analysis of the Atherosclerosis Risk in the Communities study." Obesity (Silver Spring). 2008;16(7):1545-51.
Brown SA, Hutchinson R, Morrisett J, et al. "Plasma lipid, lipoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb. 1993;13(8):1139-58.
Bressler J, Folsom AR, Couper DJ, Volcik KA, Boerwinkle E. "Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2010;171(1):14-23.
Bressler J, Mosley TH, Penman A, et al. "Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study." Am J Med Genet B Neuropsychiatr Genet. 2017;174(3):269-282.
Bressler J, Fornage M, Hanis CL, et al. "The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts." BMC Med Genet. 2009;10:56.
Bressler J, Kao LWH, Pankow JS, Boerwinkle E. "Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study." PLoS One. 2010;5(5):e10521.
Bressler J, Fornage M, Demerath EW, et al. "Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study." Neurology. 2013;80(1):92-9.
Bressler J, Yu B, Mosley TH, et al. "Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study." Transl Psychiatry. 2017;7(7):e1173.
Bressler J, Franceschini N, Demerath EW, Mosley TH, Folsom AR. "Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study." BMC Med Genet. 2015;16:52.
Brautbar A, Pompeii LA, Dehghan A, et al. "A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies." Atherosclerosis. 2012;223(2):421-6.
Brancati FL, Kao WH, Folsom AR, Watson RL, Szklo M. "Incident type 2 diabetes mellitus in African American and white adults: the Atherosclerosis Risk in Communities Study." JAMA. 2000;283(17):2253-9.
Bradshaw PT, Monda KL. "Metabolic syndrome in healthy obese, overweight, and normal weight individuals: the Atherosclerosis Risk in Communities Study." Obesity (Silver Spring). 2013;21(1):203-9.
Borrell LN, Beck JD, Heiss G. "Socioeconomic disadvantage and periodontal disease: the Dental Atherosclerosis Risk in Communities study." Am J Public Health. 2006;96(2):332-9.
Borrell LN, Diez Roux AV, Rose K, Catellier D, Clark BL. "Neighbourhood characteristics and mortality in the Atherosclerosis Risk in Communities Study." Int J Epidemiol. 2004;33(2):398-407.
Boraska V, Jerončić A, Colonna V, et al. "Genome-wide meta-analysis of common variant differences between men and women." Hum Mol Genet. 2012;21(21):4805-15.
Boland LL, Folsom AR, Sorlie PD, et al. "Occurrence of unrecognized myocardial infarction in subjects aged 45 to 65 years (the ARIC study)." Am J Cardiol. 2002;90(9):927-31.
Böger CA, Chen M-H, Tin A, et al. "CUBN is a gene locus for albuminuria." J Am Soc Nephrol. 2011;22(3):555-70.
Blair CK, Folsom AR, Knopman DS, Bray MS, Mosley TH, Boerwinkle E. "APOE genotype and cognitive decline in a middle-aged cohort." Neurology. 2005;64(2):268-76.
Bis JC, White CC, Franceschini N, et al. "Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):359-64.
Bis JC, Kavousi M, Franceschini N, et al. "Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque." Nat Genet. 2011;43(10):940-7.
Bis JC, Destefano A, Liu X, et al. "Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium." PLoS One. 2014;9(6):e99798.
Bis JC, Sitlani C, Irvin R, et al. "Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium." PLoS One. 2015;10(10):e0140496.
Huang T, Wang T, Zheng Y, et al. "Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study." JAMA Netw Open. 2019;2(9):e1910915.
Bien SA, Pankow JS, Haessler J, et al. "Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium." Diabetologia. 2017;60(12):2384-2398.
Bielinski SJ, Pankow JS, Folsom AR, North KE, Boerwinkle E. "TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2008;51(6):968-70.
Bidulescu A, Rose KM, Wolf SH, Rosamond WD. "Occupation recorded on certificates of death compared with self-report: the Atherosclerosis Risk in Communities (ARIC) Study." BMC Public Health. 2007;7:229.
Bidulescu A, Chambless LE, Siega-Riz A M, Zeisel SH, Heiss G. "Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study." Nutr J. 2009;8:14.
Berndt SI, Gustafsson S, Mägi R, et al. "Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture." Nat Genet. 2013;45(5):501-12.
Bensen JT, Li R, Hutchinson RG, Province MA, Tyroler HA. "Family history of coronary heart disease and pre-clinical carotid artery atherosclerosis in African-Americans and whites: the ARIC study: Atherosclerosis Risk in Communities." Genet Epidemiol. 1999;16(2):165-78.
Benjamin EJ, Rice KM, Arking DE, et al. "Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry." Nat Genet. 2009;41(8):879-81.
Bello NA, Cheng S, Claggett B, et al. "Association of Weight and Body Composition on Cardiac Structure and Function in the ARIC Study (Atherosclerosis Risk in Communities)." Circ Heart Fail. 2016;9(8).
Begum F, Ruczinski I, Li S, et al. "Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort." Genet Epidemiol. 2016;40(1):81-8.
Barbalic M, Dupuis J, Dehghan A, et al. "Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels." Hum Mol Genet. 2010;19(9):1863-72.
Avery CL, Sethupathy P, Buyske S, et al. "Fine-mapping and initial characterization of QT interval loci in African Americans." PLoS Genet. 2012;8(8):e1002870.
Avery CL, Sitlani CM, Arking DE, et al. "Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval." Pharmacogenomics J. 2014;14(1):6-13.
Avery CL, Mills KT, Chambless LE, et al. "Long-term association between self-reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study." Eur J Heart Fail. 2010;12(3):232-8.
Assimes TL, Knowles JW, Priest JR, et al. "Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease." Hum Genet. 2008;123(4):399-408.
Asselbergs FW, Guo Y, van Iperen EPA, et al. "Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci." Am J Hum Genet. 2012;91(5):823-38.
Ashar FN, Moes A, Moore AZ, et al. "Association of mitochondrial DNA levels with frailty and all-cause mortality." J Mol Med (Berl). 2015;93(2):177-186.
Artigas MSoler, Loth DW, Wain LV, et al. "Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function." Nat Genet. 2011;43(11):1082-90.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Arnett DK, Rautaharju P, Crow R, et al. "Black-white differences in electrocardiographic left ventricular mass and its association with blood pressure (the ARIC study). Atherosclerosis Risk in Communities." Am J Cardiol. 1994;74(3):247-52.
Arnett DK, Tyroler HA, Burke G, Hutchinson R, Howard G, Heiss G. "Hypertension and subclinical carotid artery atherosclerosis in blacks and whites. The Atherosclerosis Risk in Communities Study. ARIC Investigators." Arch Intern Med. 1996;156(17):1983-9.
Arking DE, M Junttila J, Goyette P, et al. "Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals." PLoS Genet. 2011;7(6):e1002158.
Arking DE, Khera A, Xing C, et al. "Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population." PLoS One. 2009;4(1):e4333.
Andrew ME, Jones DW, Wofford MR, et al. "Ethnicity and unprovoked hypokalemia in the Atherosclerosis Risk in Communities Study." Am J Hypertens. 2002;15(7 Pt 1):594-9.
Amendola LM, Dorschner MO, Robertson PD, et al. "Actionable exomic incidental findings in 6503 participants: challenges of variant classification." Genome Res. 2015;25(3):305-15.
Alonso A, Krijthe BP, Aspelund T, et al. "Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium." J Am Heart Assoc. 2013;2(2):e000102.
Alonso A, Steffen LM, Folsom AR. "Dairy intake and changes in blood pressure over 9 years: the ARIC study." Eur J Clin Nutr. 2009;63(10):1272-5.
Alonso A, Mosley TH, Gottesman RF, Catellier D, Sharrett AR, Coresh J. "Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study." J Neurol Neurosurg Psychiatry. 2009;80(11):1194-201.