ARIC Publications
Six-year changes in N-terminal pro-brain natriuretic peptide and changes in weight and risk of obesity." Obesity (Silver Spring). 2021;29(7):1215-1222.
"Cardiovascular biomarkers and subclinical brain disease in the atherosclerosis risk in communities study." Stroke. 2013;44(7):1803-8.
"Ceruloplasmin and heart failure in the Atherosclerosis Risk in Communities study." Circ Heart Fail. 2013;6(5):936-43.
"Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants." Alzheimers Dement. 2021.
"The shared allelic architecture of adiponectin levels and coronary artery disease." Atherosclerosis. 2013;229(1):145-8.
"Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals." PLoS Genet. 2012;8(3):e1002607.
"Genome-wide meta-analyses of smoking behaviors in African Americans." Transl Psychiatry. 2012;2:e119.
"Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function." Nat Commun. 2018;9(1):2098.
"Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949)." Mol Psychiatry. 2015;20(2):183-92.
"Sex difference in high density lipoprotein cholesterol in six countries." Am J Epidemiol. 1996;143(11):1100-6.
"Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk." Nat Genet. 2017;49(6):834-841.
"Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair." Nat Genet. 2015;47(11):1294-1303.
"Alcohol Consumption and Risk of Hospitalizations and Mortality in the Atherosclerosis Risk in Communities Study." Alcohol Clin Exp Res. 2020;44(8):1646-1657.
"Kidney Function and Fracture Risk: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2016;67(2):218-226.
"Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes." J Thromb Haemost. 2018;16(12):2432-2441.
"Circulating ceruloplasmin, ceruloplasmin-associated genes and the incidence of venous thromboembolism in the Atherosclerosis Risk in Communities study." J Thromb Haemost. 2019;17(5):818-826.
"Circulating ceruloplasmin, ceruloplasmin-associated genes, and the incidence of atrial fibrillation in the atherosclerosis risk in communities study." Int J Cardiol. 2017;241:223-228.
"Prospective assessment of estrogen replacement therapy and cognitive functioning: atherosclerosis risk in communities study." Am J Epidemiol. 2001;154(8):733-9.
"The relationship between temporal changes in blood pressure and changes in cognitive function: atherosclerosis risk in communities (ARIC) study." Prev Med. 2002;35(3):258-63.
"A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration." Hum Mol Genet. 2016;25(2):358-70.
"Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions." Am J Epidemiol. 2019;188(6):1033-1054.
"A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology." Blood. 2019;133(9):967-977.
"Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study." Hum Mol Genet. 2017;26(17):3442-3450.
"Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study." PLoS One. 2017;12(1):e0167742.
"Retinal signs and 20-year cognitive decline in the Atherosclerosis Risk in Communities Study." Neurology. 2018;90(13):e1158-e1166.
"A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study." Alzheimers Dement (N Y). 2017;3(3):410-415.
"Hearing impairment and missing cognitive test scores in a population-based study of older adults: The Atherosclerosis Risk in Communities neurocognitive study." Alzheimers Dement. 2021.
"Relationship of Cigarette Smoking and Time of Quitting with Incident Dementia and Cognitive Decline." J Am Geriatr Soc. 2020;68(2):337-345.
"Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study." Alzheimers Dement. 2019;15(3):477-486.
"Hearing Impairment and Physical Function and Falls in the Atherosclerosis Risk in Communities Hearing Pilot Study." J Am Geriatr Soc. 2016;64(4):906-8.
"Hearing impairment and cognitive decline: a pilot study conducted within the atherosclerosis risk in communities neurocognitive study." Am J Epidemiol. 2015;181(9):680-90.
"Adiponectin and leptin levels in migraineurs in the Atherosclerosis Risk in Communities Study." Neurology. 2014;83(24):2211-8.
"Polyunsaturated fats, carbohydrates and carotid disease: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI study." Atherosclerosis. 2016;251:361-366.
"Obesity, Insulin Resistance, and Incident Small Vessel Disease on Magnetic Resonance Imaging: Atherosclerosis Risk in Communities Study." Stroke. 2015;46(11):3131-6.
"Intracranial atherosclerosis and dementia: The Atherosclerosis Risk in Communities (ARIC) Study." Neurology. 2017;88(16):1556-1563.
"The metabolic syndrome and cognitive decline in the Atherosclerosis Risk in Communities study (ARIC)." Dement Geriatr Cogn Disord. 2014;38(5-6):337-46.
"Association of Dietary Patterns in Midlife and Cognitive Function in Later Life in US Adults Without Dementia." JAMA Netw Open. 2019;2(12):e1916641.
"Mitochondrial DNA copy number and diabetes: the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open Diabetes Res Care. 2020;8(1).
"Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium." Biol Psychiatry. 2015;77(8):749-63.
"Risk of Ischemic Stroke Increases Over the Spectrum of Metabolic Syndrome Severity." Stroke. 2020;51(8):2548-2552.
"Associations of a metabolic syndrome severity score with coronary heart disease and diabetes in fasting vs. non-fasting individuals." Nutr Metab Cardiovasc Dis. 2020;30(1):92-98.
"Metabolic Syndrome and Risk of Ischemic Stroke in Atrial Fibrillation: ARIC Study." Stroke. 2019;50(11):3045-3050.
"Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium." PLoS One. 2016;11(3):e0144997.
"Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study." Lancet. 2008;372(9654):1953-61.
"Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels." Circulation. 2011;123(7):731-8.
"Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts." Circ Cardiovasc Genet. 2009;2(2):125-33.
"Heart rate-corrected QT interval prolongation predicts risk of coronary heart disease in black and white middle-aged men and women: the ARIC study." J Am Coll Cardiol. 2004;43(4):565-71.
"Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes: the ARIC Study. Atherosclerosis Risk In Communities." Circulation. 2000;102(11):1239-44.
"Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci." Hum Mol Genet. 2015;24(15):4464-79.
"Genome-wide association study of age at menarche in African-American women." Hum Mol Genet. 2013;22(16):3329-46.
"Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study." Obesity (Silver Spring). 2011;19(9):1866-72.
"Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies." Psychol Med. 2016;46(8):1613-23.
"Alcohol consumption and ultrasonographically assessed carotid artery wall thickness and distensibility. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Circulation. 1993;88(6):2787-93.
"Periodontal disease and incident dementia: The Atherosclerosis Risk in Communities Study (ARIC)." Neurology. 2020;95(12):e1660-e1671.
"Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans." PLoS One. 2011;6(1):e14581.
"Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants." Heart Rhythm. 2013;10(3):401-8.
"Development and Validation of a Sudden Cardiac Death Prediction Model for the General Population." Circulation. 2016;134(11):806-16.
"An Epigenome-Wide Association Study of Obesity-Related Traits." Am J Epidemiol. 2018;187(8):1662-1669.
"Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents." Lancet. 2016;388(10046):776-86.
"Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community." Sci Rep. 2019;9(1):13156.
"Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility." Nat Genet. 2014;46(3):234-44.
"The Association of Dietary Choline and Betaine With the Risk of Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2020;43(11):2840-2846.
"Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants." Stroke. 2014;45(1):24-36.
"Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts." Diabetes Care. 2022;45(3):674-683.
"Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program." Commun Biol. 2022;5(1):756.
"Neighborhood of residence and incidence of coronary heart disease." N Engl J Med. 2001;345(2):99-106.
"Socioeconomic disadvantage and change in blood pressure associated with aging." Circulation. 2002;106(6):703-10.
"Social inequalities and atherosclerosis. The atherosclerosis risk in communities study." Am J Epidemiol. 1995;141(10):960-72.
"Neighbourhood differences in diet: the Atherosclerosis Risk in Communities (ARIC) Study." J Epidemiol Community Health. 1999;53(1):55-63.
"The relationship of active and passive smoking to carotid atherosclerosis 12-14 years later." Prev Med. 1995;24(1):48-55.
"Area characteristics and individual-level socioeconomic position indicators in three population-based epidemiologic studies." Ann Epidemiol. 2001;11(6):395-405.
"Neighborhood environments and coronary heart disease: a multilevel analysis." Am J Epidemiol. 1997;146(1):48-63.
"Diet patterns and the incidence of age-related macular degeneration in the Atherosclerosis Risk in Communities (ARIC) study." Br J Ophthalmol. 2020;104(8):1070-1076.
"Arterial stiffness is greater in African Americans than in whites: evidence from the Forsyth County, North Carolina, ARIC cohort." Am J Hypertens. 2004;17(4):304-13.
"Association of educational achievement with pulsatile arterial diameter change of the common carotid artery: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1992." Am J Epidemiol. 2000;152(7):617-27.
"Traditional and nontraditional glycemic markers and risk of peripheral artery disease: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2018;274:86-93.
"Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies." Lancet Neurol. 2020;19(1):61-70.
"Retinal vascular caliber and the development of hypertension: a meta-analysis of individual participant data." J Hypertens. 2014;32(2):207-15.
" " "