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ARIC Publications

Lee AK, Warren B, Lee CJ, et al. "The Association of Severe Hypoglycemia With Incident Cardiovascular Events and Mortality in Adults With Type 2 Diabetes." Diabetes Care. 2018;41(1):104-111.
Kim ED, Tanaka H, Ballew SH, Sang Y, Heiss G, Coresh JJ. "Associations Between Kidney Disease Measures and Regional Pulse Wave Velocity in a Large Community-Based Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(5):682-690.
Johansen MC, Shah AM, Lirette ST, Griswold M, Mosley TH, Solomon SD. "Associations of Echocardiography Markers and Vascular Brain Lesions: The ARIC Study." J Am Heart Assoc. 2018;7(24):e008992.
Hicks CW, Yang C, Ndumele CE, et al. "Associations of Obesity With Incident Hospitalization Related to Peripheral Artery Disease and Critical Limb Ischemia in the ARIC Study." J Am Heart Assoc. 2018;7(16):e008644.
Lutsey PL, Norby FL, Alonso A, Cushman M, Chen LYee, Michos ED. "Atrial fibrillation and venous thromboembolism: evidence of bidirectionality in the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2018;16(4):670-679.
Caughey MC, Qiao Y, Windham BGwen, Gottesman RF, Mosley TH. "Carotid Intima-Media Thickness and Silent Brain Infarctions in a Biracial Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2018;31(8):869-875.
Guo L, Akahori H, Harari E, et al. "CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis." J Clin Invest. 2018;128(3):1106-1124.
Matsushita K, Kwak L, Ballew SH, et al. "Chronic kidney disease measures and the risk of abdominal aortic aneurysm." Atherosclerosis. 2018;279:107-113.
Hu EA, Selvin E, Grams ME, Steffen LM, Coresh JJ. "Coffee Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(2):214-222.
Suri FMK, Zhou J, Qiao Y, et al. "Cognitive impairment and intracranial atherosclerotic stenosis in general population." Neurology. 2018;90(14):e1240-e1247.
Lin H, van Setten J, Smith AV, et al. "Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval." Circ Genom Precis Med. 2018;11(5):e002037.
Macri V, Brody JA, Arking DE, et al. "Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction." Circ Genom Precis Med. 2018;11(5):e001663.
Ashar FN, Mitchell RN, Albert CM, et al. "A comprehensive evaluation of the genetic architecture of sudden cardiac arrest." Eur Heart J. 2018;39(44):3961-3969.
Nandakumar P, Morrison AC, Grove ML, Boerwinkle E. "Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation." Medicine (Baltimore). 2018;97(33):e11865.
Cuthbertson CC, Kucharska-Newton AMaria, Faurot KR, et al. "Controlling for Frailty in Pharmacoepidemiologic Studies of Older Adults: Validation of an Existing Medicare Claims-based Algorithm." Epidemiology. 2018;29(4):556-561.
Liang J, Le TH, Edwards DRVelez, et al. "Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2018;14(5):e1007345.
Sood SL, Cheng D, Ragni M, et al. "A cross-sectional analysis of cardiovascular disease in the hemophilia population." Blood Adv. 2018;2(11):1325-1333.
"Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies." Clin Chem. 2018;64(1):183-191.
Silvestre OM, Nadruz W, Roca GQuerejeta, et al. "Declining Lung Function and Cardiovascular Risk: The ARIC Study." J Am Coll Cardiol. 2018;72(10):1109-1122.
Natarajan P, Peloso GM, Zekavat SMaryam, et al. "Deep-coverage whole genome sequences and blood lipids among 16,324 individuals." Nat Commun. 2018;9(1):3391.
Warren B, Rebholz CM, Sang Y, Lee AK, Coresh JJ, Selvin E. "Diabetes and Trajectories of Estimated Glomerular Filtration Rate: A Prospective Cohort Analysis of the Atherosclerosis Risk in Communities Study." Diabetes Care. 2018;41(8):1646-1653.
Kubota Y, Folsom AR, Pankow JS, Wagenknecht LE. "Diabetes-related factors and abdominal aortic aneurysm events: the Atherosclerotic Risk in Communities Study." Ann Epidemiol. 2018;28(2):102-106.e1.
Wang Y, Yang H, Huynh Q, Nolan M, Negishi K. "Diagnosis of Nonischemic Stage B Heart Failure in Type 2 Diabetes Mellitus: Optimal Parameters for Prediction of Heart Failure." JACC Cardiovasc Imaging. 2018;11(10):1390-1400.
Warren B, Lee AK, Ballantyne CM, et al. "Diagnostic Performance of 1,5-Anhydroglucitol Compared to 2-H Glucose in the Atherosclerosis Risk in Communities Study." Clin Chem. 2018;64(10):1536-1537.
Brigham EP, Steffen LM, London SJ, et al. "Diet Pattern and Respiratory Morbidity in the Atherosclerosis Risk in Communities Study." Ann Am Thorac Soc. 2018;15(6):675-682.
Seidelmann SB, Claggett B, Cheng S, et al. "Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis." Lancet Public Health. 2018;3(9):e419-e428.
Kocarnik JM, Richard M, Graff M, et al. "Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study." Hum Mol Genet. 2018;27(16):2940-2953.
Ward-Caviness CK, Huffman JE, Everett K, et al. "DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis." Blood. 2018;132(17):1842-1850.
Liu C, Marioni RE, Hedman ÅK, et al. "A DNA methylation biomarker of alcohol consumption." Mol Psychiatry. 2018;23(2):422-433.
Jovanova OStory, Nedeljkovic I, Spieler D, et al. "DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies." JAMA Psychiatry. 2018;75(9):949-959.
Arora S, Matsushita K, Qamar A, R Stacey B. "Early versus late percutaneous revascularization in patients hospitalized with non ST-segment elevation myocardial infarction: The atherosclerosis risk in communities surveillance study." Catheter Cardiovasc Interv. 2018;91(2):253-259.
Joshu CE, Barber JR, Coresh JJ, et al. "Enhancing the Infrastructure of the Atherosclerosis Risk in Communities (ARIC) Study for Cancer Epidemiology Research: ARIC Cancer." Cancer Epidemiol Biomarkers Prev. 2018;27(3):295-305.
Dhana K, Braun KVE, Nano J, et al. "An Epigenome-Wide Association Study of Obesity-Related Traits." Am J Epidemiol. 2018;187(8):1662-1669.
Wang X, Pan Y, Zhu H, et al. "An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression." Clin Epigenetics. 2018;10:3.
Selvin E, Warren B, He X, Sacks DB. "Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol." Clin Chem. 2018;64(5):843-850.
Weng L-C, Roetker NS, Lutsey PL, et al. "Evaluation of the relationship between plasma lipids and abdominal aortic aneurysm: A Mendelian randomization study." PLoS One. 2018;13(4):e0195719.
Jian X, Satizabal CL, Smith AV, et al. "Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging." Stroke. 2018;49(8):1812-1819.
Prins BP, Mead TJ, Brody JA, et al. "Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6." Genome Biol. 2018;19(1):87.
Bihlmeyer NA, Brody JA, Smith A V, et al. "ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals." Circ Genom Precis Med. 2018;11(1):e001758.
Wu B. "Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits." Comput Math Methods Med. 2018;2018:2564531.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Kalbaugh CA, Loehr LR, Wruck L, et al. "Frequency of Care and Mortality Following an Incident Diagnosis of Peripheral Artery Disease in the Inpatient or Outpatient Setting: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
Hodonsky CJo, Schurmann C, Schick UM, et al. "Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study." Am J Hematol. 2018.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Fernández-Rhodes L, Malinowski JR, Wang Y, et al. "The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis." PLoS One. 2018;13(7):e0200486.
Robinson-Cohen C, Bartz TM, Lai D, et al. "Genetic Variants Associated with Circulating Fibroblast Growth Factor 23." J Am Soc Nephrol. 2018;29(10):2583-2592.
Li C, Grove ML, Yu B, Jones BC, Morrison A, Boerwinkle E. "Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population." Hum Genet. 2018;137(1):85-94.
Seidelmann SB, Feofanova E, Yu B, et al. "Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk." J Am Coll Cardiol. 2018;72(15):1763-1773.
Blue EE, Bis JC, Dorschner MO, et al. "Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project." Dement Geriatr Cogn Disord. 2018;45(1-2):1-17.
Young KL, Graff M, Fernández-Rhodes L. "Genetics of Obesity in Diverse Populations." Curr Diab Rep. 2018;18(12):145.
Ligthart S, Vaez A, Võsa U, et al. "Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet. 2018;103(5):691-706.
Teumer A, Chaker L, Groeneweg S, et al. "Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.
Otto MC de Olive, Lemaitre RN, Sun Q, et al. "Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium." PLoS One. 2018;13(5):e0196951.
Napier MD, Franceschini N, Gondalia R, et al. "Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy." Sci Rep. 2018;8(1):5675.
Jiang X, O'Reilly PF, Aschard H, et al. "Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels." Nat Commun. 2018;9(1):260.
Vojinovic D, Adams HH, Jian X, et al. "Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume." Nat Commun. 2018;9(1):3945.
Klimentidis YC, Raichlen DA, Bea J, et al. "Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE." Int J Obes (Lond). 2018;42(6):1161-1176.
Loomis SJ, Li M, Maruthur NM, et al. "Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study." Diabetes. 2018;67(8):1684-1696.
Tereshchenko LG, Sotoodehnia N, Sitlani CM, et al. "Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)." J Am Heart Assoc. 2018;7(8).
Keaton JM, Gao C, Guan M, et al. "Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans." Genet Epidemiol. 2018;42(6):559-570.
Smith CE, Follis JL, Dashti HS, et al. "Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent." Mol Nutr Food Res. 2018;62(3).
Biering-Sørensen T, Kabir M, Waks JW, et al. "Global ECG Measures and Cardiac Structure and Function: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Arrhythm Electrophysiol. 2018;11(3):e005961.
"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017." Lancet. 2018;392(10159):1789-1858.
Franceschini N, Giambartolomei C, de Vries PS, et al. "GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes." Nat Commun. 2018;9(1):5141.
Offenbacher S, Jiao Y, Kim SJ, et al. "GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation." Nat Commun. 2018;9(1):3686.
Tanaka H, Palta P, Folsom AR, et al. "Habitual physical activity and central artery stiffening in older adults: the Atherosclerosis Risk in Communities study." J Hypertens. 2018;36(9):1889-1894.
Oelsner EC, Balte PP, Cassano PA, et al. "Harmonization of Respiratory Data From 9 US Population-Based Cohorts: The NHLBI Pooled Cohorts Study." Am J Epidemiol. 2018;187(11):2265-2278.
Witt LS, Rotter J, Stearns SC, et al. "Heart Failure and Cognitive Impairment in the Atherosclerosis Risk in Communities (ARIC) Study." J Gen Intern Med. 2018;33(10):1721-1728.
Ishigami J, Grams ME, Naik RP, et al. "Hemoglobin, Albuminuria, and Kidney Function in Cardiovascular Risk: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(2).
Matsushita K, Kwak L, Yang C, et al. "High-sensitivity cardiac troponin and natriuretic peptide with risk of lower-extremity peripheral artery disease: the Atherosclerosis Risk in Communities (ARIC) Study." Eur Heart J. 2018;39(25):2412-2419.
Sengeløv M, Cheng S, Biering-Sørensen T, et al. "Ideal Cardiovascular Health and the Prevalence and Severity of Aortic Stenosis in Elderly Patients." J Am Heart Assoc. 2018;7(3).
Coban-Akdemir Z, White JJ, Song X, et al. "Identifying Genes Whose Mutant Transcripts Cause Dominant Disease Traits by Potential Gain-of-Function Alleles." Am J Hum Genet. 2018;103(2):171-187.
Beck JD, Moss KL, Morelli T. "In search of appropriate measures of periodontal status: The Periodontal Profile Phenotype (P ) system." J Periodontol. 2018;89(2):166-175.
Lin J, Sun J, Wang S, et al. "In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study." Psychoneuroendocrinology. 2018;96:179-187.
Li D, Misialek JR, Huang F, Windham GB, Yu F. "Independent Association of Plasma Hydroxysphingomyelins With Physical Function in the Atherosclerosis Risk in Communities (ARIC) Study." J Gerontol A Biol Sci Med Sci. 2018;73(8):1103-1110.
Cowan LT, Lutsey PL, Pankow JS, Matsushita K, Ishigami J. "Inpatient and Outpatient Infection as a Trigger of Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2018;7(22):e009683.
Mok Y, Ballew SH, Bash LD, et al. "International Validation of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention in Post-MI Patients: A Collaborative Analysis of the Chronic Kidney Disease Prognosis Consortium and the Risk Validation Scientific Committee." J Am Heart Assoc. 2018;7(14).
Chatterjee R, Davenport CA, Raffield LM, et al. "KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts." PLoS One. 2018;13(8):e0203213.
Secora A, G Alexander C, Ballew SH, Coresh JJ. "Kidney Function, Polypharmacy, and Potentially Inappropriate Medication Use in a Community-Based Cohort of Older Adults." Drugs Aging. 2018;35(8):735-750.
Sung YJ, Winkler TW, Fuentes Lde Las, et al. "A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure." Am J Hum Genet. 2018;102(3):375-400.