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ARIC Publications

2019
Caughey MC, Derebail VK, Key NS, Reiner AP, Gottesman RF, Kshirsagar AV. "Thirty-year risk of ischemic stroke in individuals with sickle cell trait and modification by chronic kidney disease: The atherosclerosis risk in communities (ARIC) study." Am J Hematol. 2019;94(12):1306-1313.
Morris AP, Le TH, Wu H, et al. "Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies." Nat Commun. 2019;10(1):29.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Twenty Year Trends and Sex Differences in Young Adults Hospitalized With Acute Myocardial Infarction." Circulation. 2019;139(8):1047-1056.
Yee SWah, Stecula A, Chien H-C, et al. "Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies." PLoS Genet. 2019;15(9):e1008208.
Kowalski MH, Qian H, Hou Z, et al. "Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations." PLoS Genet. 2019;15(12):e1008500.
2018
Haring B, Selvin E, He X, et al. "Adherence to the Dietary Approaches to Stop Hypertension Dietary Pattern and Risk of Abdominal Aortic Aneurysm: Results From the ARIC Study." J Am Heart Assoc. 2018;7(21):e009340.
Fernandes-Silva MM, Shah AM, Claggett B, et al. "Adiposity, body composition and ventricular-arterial stiffness in the elderly: the Atherosclerosis Risk in Communities Study." Eur J Heart Fail. 2018;20(8):1191-1201.
Garg PK, O'Neal WT, Chen LYee, Loehr LR, Sotoodehnia N, Soliman EZ. "American Heart Association's Life Simple 7 and Risk of Atrial Fibrillation in a Population Without Known Cardiovascular Disease: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
Mok Y, Sang Y, Ballew SH, et al. "American Heart Association's Life's Simple 7 at Middle Age and Prognosis After Myocardial Infarction in Later Life." J Am Heart Assoc. 2018;7(4).
Charles BA, Hsieh MM, Adeyemo AA, et al. "Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia." PLoS One. 2018;13(3):e0194400.
Federspiel JJ, Sueta CA, Kucharska-Newton AMaria, et al. "Antihypertensive adherence and outcomes among community-dwelling Medicare beneficiaries: the Atherosclerosis Risk in Communities Study." J Eval Clin Pract. 2018;24(1):48-55.
Hughes TM, Wagenknecht LE, Craft S, et al. "Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study." Neurology. 2018;90(14):e1248-e1256.
Guo Y, Musani SK, Sims M, Pearson TA, DeBoer MD. "Assessing the added predictive ability of a metabolic syndrome severity score in predicting incident cardiovascular disease and type 2 diabetes: the Atherosclerosis Risk in Communities Study and Jackson Heart Study." Diabetol Metab Syndr. 2018;10:42.
Johnson EL, Krauss GL, Lee AK, et al. "Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." JAMA Neurol. 2018;75(11):1375-1382.
Choi SHoan, Weng L-C, Roselli C, et al. "Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation." JAMA. 2018;320(22):2354-2364.
Chen LYee, Norby FL, Gottesman RF, et al. "Association of Atrial Fibrillation With Cognitive Decline and Dementia Over 20 Years: The ARIC-NCS (Atherosclerosis Risk in Communities Neurocognitive Study)." J Am Heart Assoc. 2018;7(6).
Yao L, Folsom AR, Alonso A, et al. "Association of carotid atherosclerosis and stiffness with abdominal aortic aneurysm: The atherosclerosis risk in communities (ARIC) study." Atherosclerosis. 2018;270:110-116.
Walker KA, Gottesman RF, Wu A, et al. "Association of Hospitalization, Critical Illness, and Infection with Brain Structure in Older Adults." J Am Geriatr Soc. 2018;66(10):1919-1926.
Norby FL, Chen LYee, Soliman EZ, Gottesman RF, Mosley TH. "Association of left ventricular hypertrophy with cognitive decline and dementia risk over 20 years: The Atherosclerosis Risk In Communities-Neurocognitive Study (ARIC-NCS)." Am Heart J. 2018;204:58-67.
Garg PK, Bartz TM, Norby FL, et al. "Association of lipoprotein-associated phospholipase A and risk of incident atrial fibrillation: Findings from 3 cohorts." Am Heart J. 2018;197:62-69.
Power MC, Lamichhane AP, Liao D, et al. "The Association of Long-Term Exposure to Particulate Matter Air Pollution with Brain MRI Findings: The ARIC Study." Environ Health Perspect. 2018;126(2):027009.
Lazarus B, Wu A, Shin J-I, et al. "Association of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study." JAMA Intern Med. 2018;178(7):903-910.
Walker KA, B Windham G, Brown CH, et al. "The Association of Mid- and Late-Life Systemic Inflammation with Brain Amyloid Deposition: The ARIC-PET Study." J Alzheimers Dis. 2018;66(3):1041-1052.
Power MC, Rawlings A, Sharrett ARichey, et al. "Association of midlife lipids with 20-year cognitive change: A cohort study." Alzheimers Dement. 2018;14(2):167-177.
Oyenuga AO, Couper DJ, Matsushita K, Boerwinkle E. "Association of monocyte myeloperoxidase with incident cardiovascular disease: The Atherosclerosis Risk in Communities Study." PLoS One. 2018;13(10):e0205310.
Li L, Selvin E, Lutsey PL, et al. "Association of N-terminal pro B-type natriuretic peptide (NT-proBNP) change with the risk of atrial fibrillation in the ARIC cohort." Am Heart J. 2018;204:119-127.
Rawlings AM, Juraschek SP, Heiss G, et al. "Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline." Neurology. 2018;91(8):e759-e768.
Bekwelem W, Norby FL, Agarwal SK, Matsushita K, Coresh JJ, Alonso A. "Association of Peripheral Artery Disease With Incident Atrial Fibrillation: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
Lee AK, Warren B, Lee CJ, et al. "The Association of Severe Hypoglycemia With Incident Cardiovascular Events and Mortality in Adults With Type 2 Diabetes." Diabetes Care. 2018;41(1):104-111.
Kim ED, Tanaka H, Ballew SH, Sang Y, Heiss G, Coresh JJ. "Associations Between Kidney Disease Measures and Regional Pulse Wave Velocity in a Large Community-Based Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(5):682-690.
Johansen MC, Shah AM, Lirette ST, Griswold M, Mosley TH, Solomon SD. "Associations of Echocardiography Markers and Vascular Brain Lesions: The ARIC Study." J Am Heart Assoc. 2018;7(24):e008992.
Hicks CW, Yang C, Ndumele CE, et al. "Associations of Obesity With Incident Hospitalization Related to Peripheral Artery Disease and Critical Limb Ischemia in the ARIC Study." J Am Heart Assoc. 2018;7(16):e008644.
Lutsey PL, Norby FL, Alonso A, Cushman M, Chen LYee, Michos ED. "Atrial fibrillation and venous thromboembolism: evidence of bidirectionality in the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2018;16(4):670-679.
Caughey MC, Qiao Y, Windham BGwen, Gottesman RF, Mosley TH. "Carotid Intima-Media Thickness and Silent Brain Infarctions in a Biracial Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2018;31(8):869-875.
Guo L, Akahori H, Harari E, et al. "CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis." J Clin Invest. 2018;128(3):1106-1124.
Matsushita K, Kwak L, Ballew SH, et al. "Chronic kidney disease measures and the risk of abdominal aortic aneurysm." Atherosclerosis. 2018;279:107-113.
Hu EA, Selvin E, Grams ME, Steffen LM, Coresh JJ. "Coffee Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(2):214-222.
Suri FMK, Zhou J, Qiao Y, et al. "Cognitive impairment and intracranial atherosclerotic stenosis in general population." Neurology. 2018;90(14):e1240-e1247.
Lin H, van Setten J, Smith AV, et al. "Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval." Circ Genom Precis Med. 2018;11(5):e002037.
Macri V, Brody JA, Arking DE, et al. "Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction." Circ Genom Precis Med. 2018;11(5):e001663.
Ashar FN, Mitchell RN, Albert CM, et al. "A comprehensive evaluation of the genetic architecture of sudden cardiac arrest." Eur Heart J. 2018;39(44):3961-3969.
Nandakumar P, Morrison AC, Grove ML, Boerwinkle E. "Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation." Medicine (Baltimore). 2018;97(33):e11865.
Cuthbertson CC, Kucharska-Newton AMaria, Faurot KR, et al. "Controlling for Frailty in Pharmacoepidemiologic Studies of Older Adults: Validation of an Existing Medicare Claims-based Algorithm." Epidemiology. 2018;29(4):556-561.
Liang J, Le TH, Edwards DRVelez, et al. "Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2018;14(5):e1007345.
Sood SL, Cheng D, Ragni M, et al. "A cross-sectional analysis of cardiovascular disease in the hemophilia population." Blood Adv. 2018;2(11):1325-1333.
"Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies." Clin Chem. 2018;64(1):183-191.
Silvestre OM, Nadruz W, Roca GQuerejeta, et al. "Declining Lung Function and Cardiovascular Risk: The ARIC Study." J Am Coll Cardiol. 2018;72(10):1109-1122.
Natarajan P, Peloso GM, Zekavat SMaryam, et al. "Deep-coverage whole genome sequences and blood lipids among 16,324 individuals." Nat Commun. 2018;9(1):3391.
Warren B, Rebholz CM, Sang Y, Lee AK, Coresh JJ, Selvin E. "Diabetes and Trajectories of Estimated Glomerular Filtration Rate: A Prospective Cohort Analysis of the Atherosclerosis Risk in Communities Study." Diabetes Care. 2018;41(8):1646-1653.
Kubota Y, Folsom AR, Pankow JS, Wagenknecht LE. "Diabetes-related factors and abdominal aortic aneurysm events: the Atherosclerotic Risk in Communities Study." Ann Epidemiol. 2018;28(2):102-106.e1.
Wang Y, Yang H, Huynh Q, Nolan M, Negishi K. "Diagnosis of Nonischemic Stage B Heart Failure in Type 2 Diabetes Mellitus: Optimal Parameters for Prediction of Heart Failure." JACC Cardiovasc Imaging. 2018;11(10):1390-1400.
Warren B, Lee AK, Ballantyne CM, et al. "Diagnostic Performance of 1,5-Anhydroglucitol Compared to 2-H Glucose in the Atherosclerosis Risk in Communities Study." Clin Chem. 2018;64(10):1536-1537.
Brigham EP, Steffen LM, London SJ, et al. "Diet Pattern and Respiratory Morbidity in the Atherosclerosis Risk in Communities Study." Ann Am Thorac Soc. 2018;15(6):675-682.
Seidelmann SB, Claggett B, Cheng S, et al. "Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis." Lancet Public Health. 2018;3(9):e419-e428.
Kocarnik JM, Richard M, Graff M, et al. "Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study." Hum Mol Genet. 2018;27(16):2940-2953.
Ward-Caviness CK, Huffman JE, Everett K, et al. "DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis." Blood. 2018;132(17):1842-1850.
Liu C, Marioni RE, Hedman ÅK, et al. "A DNA methylation biomarker of alcohol consumption." Mol Psychiatry. 2018;23(2):422-433.
Jovanova OStory, Nedeljkovic I, Spieler D, et al. "DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies." JAMA Psychiatry. 2018;75(9):949-959.
Arora S, Matsushita K, Qamar A, R Stacey B. "Early versus late percutaneous revascularization in patients hospitalized with non ST-segment elevation myocardial infarction: The atherosclerosis risk in communities surveillance study." Catheter Cardiovasc Interv. 2018;91(2):253-259.
Joshu CE, Barber JR, Coresh JJ, et al. "Enhancing the Infrastructure of the Atherosclerosis Risk in Communities (ARIC) Study for Cancer Epidemiology Research: ARIC Cancer." Cancer Epidemiol Biomarkers Prev. 2018;27(3):295-305.
Dhana K, Braun KVE, Nano J, et al. "An Epigenome-Wide Association Study of Obesity-Related Traits." Am J Epidemiol. 2018;187(8):1662-1669.
Wang X, Pan Y, Zhu H, et al. "An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression." Clin Epigenetics. 2018;10:3.
Selvin E, Warren B, He X, Sacks DB. "Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol." Clin Chem. 2018;64(5):843-850.
Weng L-C, Roetker NS, Lutsey PL, et al. "Evaluation of the relationship between plasma lipids and abdominal aortic aneurysm: A Mendelian randomization study." PLoS One. 2018;13(4):e0195719.
Jian X, Satizabal CL, Smith AV, et al. "Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging." Stroke. 2018;49(8):1812-1819.
Prins BP, Mead TJ, Brody JA, et al. "Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6." Genome Biol. 2018;19(1):87.
Bihlmeyer NA, Brody JA, Smith A V, et al. "ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals." Circ Genom Precis Med. 2018;11(1):e001758.
Wu B. "Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits." Comput Math Methods Med. 2018;2018:2564531.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Kalbaugh CA, Loehr LR, Wruck L, et al. "Frequency of Care and Mortality Following an Incident Diagnosis of Peripheral Artery Disease in the Inpatient or Outpatient Setting: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
Hodonsky CJo, Schurmann C, Schick UM, et al. "Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study." Am J Hematol. 2018.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Fernández-Rhodes L, Malinowski JR, Wang Y, et al. "The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis." PLoS One. 2018;13(7):e0200486.
Robinson-Cohen C, Bartz TM, Lai D, et al. "Genetic Variants Associated with Circulating Fibroblast Growth Factor 23." J Am Soc Nephrol. 2018;29(10):2583-2592.
Li C, Grove ML, Yu B, Jones BC, Morrison A, Boerwinkle E. "Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population." Hum Genet. 2018;137(1):85-94.
Seidelmann SB, Feofanova E, Yu B, et al. "Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk." J Am Coll Cardiol. 2018;72(15):1763-1773.
Blue EE, Bis JC, Dorschner MO, et al. "Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project." Dement Geriatr Cogn Disord. 2018;45(1-2):1-17.
Young KL, Graff M, Fernández-Rhodes L. "Genetics of Obesity in Diverse Populations." Curr Diab Rep. 2018;18(12):145.
Ligthart S, Vaez A, Võsa U, et al. "Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet. 2018;103(5):691-706.
Teumer A, Chaker L, Groeneweg S, et al. "Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.

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