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ARIC Publications

2019
Lindström S, Wang L, Smith EN, et al. "Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism." Blood. 2019;134(19):1645-1657.
Oyenuga AO, Folsom AR, Cheng S, Tanaka H. "Greater Adherence to Life's Simple 7 Is Associated With Less Arterial Stiffness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2019;32(8):769-776.
Reed NS, Betz JF, Kucharska-Newton AMaria, Lin FR. "Hearing loss and satisfaction with healthcare: An unexplored relationship." J Am Geriatr Soc. 2019;67(3):624-626.
Shukla A, Reed N, Armstrong NM, Lin FR, Deal JA. "Hearing Loss, Hearing Aid Use and Depressive Symptoms in Older Adults - Findings from the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Gerontol B Psychol Sci Soc Sci. 2019.
Loomis SJ, Tin A, Coresh JJ, et al. "Heritability analysis of nontraditional glycemic biomarkers in the Atherosclerosis Risk in Communities Study." Genet Epidemiol. 2019;43(7):776-785.
Selvaraj S, Seidelmann S, Silvestre OM, et al. "HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study." Hypertension. 2019;73(1):68-74.
Pokharel Y, Mouhanna F, Schneider ALC, et al. "High-Sensitive Troponin T, Natriuretic Peptide, and Cognitive Change." J Am Geriatr Soc. 2019;67(11):2353-2361.
Jia X, Sun W, Hoogeveen RC, et al. "High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study." Circulation. 2019;139(23):2642-2653.
Kubota Y, Alonso A, Heckbert SR, Norby FL. "Homocysteine and Incident Atrial Fibrillation: The Atherosclerosis Risk in Communities Study and the Multi-Ethnic Study of Atherosclerosis." Heart Lung Circ. 2019;28(4):615-622.
Wong E, Ballew SH, Daya N, et al. "Hospitalization Risk among Older Adults with Chronic Kidney Disease." Am J Nephrol. 2019;50(3):212-220.
Marrone MT, Selvin E, Barber JR, Platz EA. "Hyperglycemia, Classified with Multiple Biomarkers Simultaneously in Men without Diabetes, and Risk of Fatal Prostate Cancer." Cancer Prev Res (Phila). 2019;12(2):103-112.
Sarnowski C, Leong A, Raffield LM, et al. "Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program." Am J Hum Genet. 2019;105(4):706-718.
Lutsey PL, Chen N, Mirabelli MC, et al. "Impaired Lung Function, Lung Disease, and Risk of Incident Dementia." Am J Respir Crit Care Med. 2019;199(11):1385-1396.
Perez-Alday EAndres, Li-Pershing Y, Bender A, et al. "Importance of the heart vector origin point definition for an ECG analysis: The Atherosclerosis Risk in Communities (ARIC) study." Comput Biol Med. 2019;104:127-138.
Pandey A, Patel KV, Vongpatanasin W, et al. "Incorporation of Biomarkers Into Risk Assessment for Allocation of Antihypertensive Medication According to the 2017 ACC/AHA High Blood Pressure Guideline: A Pooled Cohort Analysis." Circulation. 2019;140(25):2076-2088.
Mounsey LA, Chang PP, Sueta CA, Matsushita K, Russell SD. "In-Hospital and Postdischarge Mortality Among Patients With Acute Decompensated Heart Failure Hospitalizations Ending on the Weekend Versus Weekday: The ARIC Study Community Surveillance." J Am Heart Assoc. 2019;8(15):e011631.
Liu J, Carnero-Montoro E, van Dongen J, et al. "An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis." Nat Commun. 2019;10(1):2581.
Almuwaqqat Z, O'Neal WT, Norby FL, et al. "Joint Associations of Obesity and NT-proBNP With the Incidence of Atrial Fibrillation in the ARIC Study." J Am Heart Assoc. 2019;8(19):e013294.
Grams ME, Surapaneni A, Ballew SH, et al. " Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis." J Am Soc Nephrol. 2019;30(10):2027-2036.
Lindström S, Brody JA, Turman C, et al. "A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.
Palta P, Sharrett ARichey, Deal JA, et al. "Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2019;15(2):273-281.
He KY, Li X, Kelly TN, et al. "Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data." Hum Genet. 2019;138(2):199-210.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Wang SY, Tan ASL, Claggett B, et al. "Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.
Decker JJ, Norby FL, Rooney MR, et al. "Metabolic Syndrome and Risk of Ischemic Stroke in Atrial Fibrillation: ARIC Study." Stroke. 2019;50(11):3045-3050.
Wang Z, Zhu C, Nambi V, et al. "Metabolomic Pattern Predicts Incident Coronary Heart Disease." Arterioscler Thromb Vasc Biol. 2019;39(7):1475-1482.
Yu B, Flexeder C, McGarrah RW, et al. "Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population." Metabolites. 2019;9(4).
Gondalia R, Baldassari A, Holliday KM, et al. "Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation." Environ Int. 2019;132:104723.
Fashanu OE, Zhao D, Schneider ALC, et al. "Mid-life serum Vitamin D concentrations were associated with incident dementia but not late-life neuropsychological performance in the Atherosclerosis Risk in Communities (ARIC) Study." BMC Neurol. 2019;19(1):244.
B Windham G, Griswold ME, Wilkening SR, et al. "Midlife Smaller and Larger Infarctions, White Matter Hyperintensities, and 20-Year Cognitive Decline: A Cohort Study." Ann Intern Med. 2019;171(6):389-396.
Walker KA, Walston J, Gottesman RF, Kucharska-Newton AMaria, Palta P. "Midlife Systemic Inflammation Is Associated With Frailty in Later Life: The ARIC Study." J Gerontol A Biol Sci Med Sci. 2019;74(3):343-349.
X Androulakis M, Sen S, Kodumuri N, et al. "Migraine Age of Onset and Association With Ischemic Stroke in Late Life: 20 Years Follow-Up in ARIC." Headache. 2019;59(4):556-566.
de Vries PS, Brown MR, Bentley AR, et al. "Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions." Am J Epidemiol. 2019;188(6):1033-1054.
Bentley AR, Sung YJ, Brown MR, et al. "Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids." Nat Genet. 2019;51(4):636-648.
Sung YJu, Fuentes Lde Las, Winkler TW, et al. "A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure." Hum Mol Genet. 2019;28(15):2615-2633.
Noordam R, Bos MM, Wang H, et al. "Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration." Nat Commun. 2019;10(1):5121.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Kapoor A, Lee D, Zhu L, et al. "Multiple variant enhancers modulate its cardiac gene expression and the QT interval." Proc Natl Acad Sci U S A. 2019;116(22):10636-10645.
Schneider ALC, Senjem ML, Wu A, et al. "Neural correlates of domain-specific cognitive decline: The ARIC-NCS Study." Neurology. 2019;92(10):e1051-e1063.
West NA, B Windham G, Knopman DS, Shibata DK, Coker LH. "Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up." Neurology. 2019;92(9):e917-e923.
Evangelou E, Gao H, Chu C, et al. "New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav. 2019;3(9):950-961.
Matsushita K, Sang Y, Chen J, et al. "Novel "Predictor Patch" Method for Adding Predictors Using Estimates From Outside Datasets　- A Proof-of-Concept Study Adding Kidney Measures to Cardiovascular Mortality Prediction." Circ J. 2019;83(9):1876-1882.
Whitman IR, Vittinghoff E, Defilippi CR, et al. "NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure." J Am Heart Assoc. 2019;8(7):e010868.
Xu J, Gaddis NC, Bartz TM, et al. "Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association." Am J Respir Crit Care Med. 2019;199(5):631-642.
Arora S, Cavender MA, Chang PP, et al. "Outcomes of decreasing versus increasing cardiac troponin in patients admitted with non-ST-segment elevation myocardial infarction: the Atherosclerosis Risk in Communities Surveillance Study." Eur Heart J Acute Cardiovasc Care. 2019:2048872619842983.
Cowan LT, Lakshminarayan K, Lutsey PL, Folsom AR, Beck J, Offenbacher S. "Periodontal disease and incident venous thromboembolism: The Atherosclerosis Risk in Communities study." J Clin Periodontol. 2019;46(1):12-19.
Floyd JS, Bloch KM, Brody JA, et al. "Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing." PLoS One. 2019;14(6):e0218115.
Pendergrass SA, Buyske S, Jeff JM, et al. "A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans." PLoS One. 2019;14(12):e0226771.
Lu Y, Ballew SH, Kwak L, et al. "Physical Activity and Subsequent Risk of Hospitalization With Peripheral Artery Disease and Critical Limb Ischemia in the ARIC Study." J Am Heart Assoc. 2019;8(21):e013534.
Gabriel KPettee, Griswold ME, Wang W, et al. "Physical activity trajectories and subsequent fall risk: ARIC Study." Prev Med. 2019;121:40-46.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Grams ME, Coresh JJ. "Plant-Based Diets and Incident CKD and Kidney Function." Clin J Am Soc Nephrol. 2019;14(5):682-691.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Coresh JJ. "Plant-Based Diets Are Associated With a Lower Risk of Incident Cardiovascular Disease, Cardiovascular Disease Mortality, and All-Cause Mortality in a General Population of Middle-Aged Adults." J Am Heart Assoc. 2019;8(16):e012865.
Folsom AR, Tang W, Basu S, Misialek JR, Couper DJ, Heckbert SR. "Plasma Concentrations of High Molecular Weight Kininogen and Prekallikrein and Venous Thromboembolism Incidence in the General Population." Thromb Haemost. 2019;119(5):834-843.
Oyenuga A, Folsom AR, Fashanu O, Aguilar D. "Plasma Galectin-3 and Sonographic Measures of Carotid Atherosclerosis in the Atherosclerosis Risk in Communities Study." Angiology. 2019;70(1):47-55.
Li D, Misialek JR, Jack CR, et al. "Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS)." Int J Mol Sci. 2019;20(7).
Berger D, Folsom AR, Schreiner PJ, et al. "Plasma total testosterone and risk of incident atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study." Maturitas. 2019;125:5-10.
Mok Y, Sang Y, Ballew SH, et al. "Premorbid levels of high-sensitivity cardiac troponin T and natriuretic peptide and prognosis after incident myocardial infarction." Am Heart J. 2019;216:62-73.
Rooney MR, Soliman EZ, Lutsey PL, et al. "Prevalence and Characteristics of Subclinical Atrial Fibrillation in a Community-Dwelling Elderly Population: The ARIC Study." Circ Arrhythm Electrophysiol. 2019;12(10):e007390.
Diab N, Daya NR, Juraschek SP, et al. "Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community." Sci Rep. 2019;9(1):13156.
Loehr LR, Soliman EZ, Poon AK, et al. "The prevalence of atrial fibrillation on 48-hour ambulatory electrocardiography in African Americans compared to Whites: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2019;216:1-8.
Lee MJeong, Deal JA, Ramulu PY, Sharrett ARichey. "Prevalence of Retinal Signs and Association With Cognitive Status: The ARIC Neurocognitive Study." J Am Geriatr Soc. 2019;67(6):1197-1203.
Polter EJ, Onyeaghala G, Lutsey PL, Folsom AR, Joshu CE, Platz EA. "Prospective Association of Serum and Dietary Magnesium with Colorectal Cancer Incidence." Cancer Epidemiol Biomarkers Prev. 2019;28(8):1292-1299.
Folsom AR, Lutsey PL, Misialek JR. "A prospective study of migraine history and venous thromboembolism in older adults." Res Pract Thromb Haemost. 2019;3(3):357-363.
Parikh RR, Folsom AR, Misialek JR, Rosamond WD, Chang PP, Tang W. "Prospective study of plasma high molecular weight kininogen and prekallikrein and incidence of coronary heart disease, ischemic stroke and heart failure." Thromb Res. 2019;182:89-94.
Sun D, Tiedt S, Yu B, et al. "A prospective study of serum metabolites and risk of ischemic stroke." Neurology. 2019;92(16):e1890-e1898.
Justice AE, Karaderi T, Highland HM, et al. "Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution." Nat Genet. 2019;51(3):452-469.
Turcot V, Lu Y, Highland HM, et al. "Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity." Nat Genet. 2019;51(7):1191-1192.
Naj AC, Lin H, Vardarajan BN, et al. "Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project." Genomics. 2019;111(4):808-818.
Merino J, Guasch-Ferré M, Ellervik C, et al. "Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis." BMJ. 2019;366:l4292.
Zhao D, Post WS, Blasco-Colmenares E, et al. "Racial Differences in Sudden Cardiac Death." Circulation. 2019;139(14):1688-1697.
Loomis SJ, Köttgen A, Li M, et al. "Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study." Sci Rep. 2019;9(1):5941.
Folsom AR, Basu S, Hong C-P, Heckbert SR, Lutsey PL, Rosamond WD. "Reasons for Differences in the Incidence of Venous Thromboembolism in Black Versus White Americans." Am J Med. 2019;132(8):970-976.
Maheshwari A, Norby FL, Roetker NS, et al. "Refining Prediction of Atrial Fibrillation-Related Stroke Using the P-CHADS-VASc Score." Circulation. 2019;139(2):180-191.
Wang S, Fashanu OE, Zhao D, et al. "Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20 Years (from the Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2019;123(2):334-340.
Madan N, Lee AK, Matsushita K, Hoogeveen RC, Ballantyne CM, Selvin E. "Relation of Isolated Systolic Hypertension and Pulse Pressure to High-Sensitivity Cardiac Troponin-T and N-Terminal pro-B-Type Natriuretic Peptide in Older Adults (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2019;124(2):245-252.
Koene RJ, M Alraies C, Norby FL, et al. "Relation of the CHADS-VASc Score to Risk of Thrombotic and Embolic Stroke in Community-Dwelling Individuals Without Atrial Fibrillation (From The Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2019;123(3):402-408.
Mamo SK, Reed NS, Sharrett ARichey, et al. "Relationship Between Domain-Specific Cognitive Function and Speech-in-Noise Performance in Older Adults: The Atherosclerosis Risk in Communities Hearing Pilot Study." Am J Audiol. 2019;28(4):1006-1014.
Inker LA, Grams ME, Levey AS, et al. "Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium." Am J Kidney Dis. 2019;73(2):206-217.
Tin A, Yu B, Ma J, et al. "Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay." J Appl Lab Med. 2019;4(1):30-39.

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