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ARIC Publications

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Lubin JH, Couper DJ, Lutsey PL, Woodward M, Yatsuya H. "Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
Parrinello CM, Matsushita K, Woodward M, Wagenknecht LE, Coresh JJ. "Risk prediction of major complications in individuals with diabetes: the Atherosclerosis Risk in Communities Study." Diabetes Obes Metab. 2016;18(9):899-906.
Alonso A, Misialek JR, Michos ED, et al. "Serum 25-hydroxyvitamin D and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Europace. 2016;18(8):1143-9.
Shrestha S, Lutsey PL, Alonso A, Huang X, Mosley TH. "Serum 25-hydroxyvitamin D concentrations in Mid-adulthood and Parkinson's disease risk." Mov Disord. 2016;31(7):972-8.
Rooney MR, Pankow JS, Sibley SD, Selvin E, Reis JP, Michos ED. "Serum calcium and incident type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Am J Clin Nutr. 2016;104(4):1023-1029.
Fyfe-Johnson AL, Alonso A, Selvin E, Bower JK, Pankow JS, Agarwal SK. "Serum fibroblast growth factor-23 and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) Study." J Hypertens. 2016;34(7):1266-72.
Lee AK, McEvoy JW, Hoogeveen RC, Ballantyne CM. "Severe Hypoglycemia and Elevated High-Sensitivity Cardiac Troponin T in Older Adults With Diabetes: The ARIC Study." J Am Coll Cardiol. 2016;68(12):1370-1.
Lutsey PL, Parrinello CM, Misialek JR, et al. "Short-term Variability of Vitamin D-Related Biomarkers." Clin Chem. 2016;62(12):1647-1653.
McEvoy JW, Chen Y, Ndumele CE, et al. "Six-Year Change in High-Sensitivity Cardiac Troponin T and Risk of Subsequent Coronary Heart Disease, Heart Failure, and Death." JAMA Cardiol. 2016;1(5):519-28.
Lutsey PL, Norby FL, Gottesman RF, et al. "Sleep Apnea, Sleep Duration and Brain MRI Markers of Cerebral Vascular Disease and Alzheimer's Disease: The Atherosclerosis Risk in Communities Study (ARIC)." PLoS One. 2016;11(7):e0158758.
Nadruz W, Claggett B, Gonçalves A, et al. "Smoking and Cardiac Structure and Function in the Elderly: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Cardiovasc Imaging. 2016;9(9):e004950.
Kats D, Patel MD, Palta P, et al. "Social support and cognition in a community-based cohort: the Atherosclerosis Risk in Communities (ARIC) study." Age Ageing. 2016;45(4):475-80.
Cobb LK, Godino JG, Selvin E, Kucharska-Newton AMaria, Coresh JJ. "Spousal Influence on Physical Activity in Middle-Aged and Older Adults: The ARIC Study." Am J Epidemiol. 2016;183(5):444-51.
Agarwal SK, Wruck L, Quibrera M, et al. "Temporal Trends in Hospitalization for Acute Decompensated Heart Failure in the United States, 1998-2011." Am J Epidemiol. 2016;183(5):462-70.
Norby FL, Soliman EZ, Chen LYee, Bengtson LGS, Loehr LR, Agarwal SK. "Trajectories of Cardiovascular Risk Factors and Incidence of Atrial Fibrillation Over a 25-Year Follow-Up: The ARIC Study (Atherosclerosis Risk in Communities)." Circulation. 2016;134(8):599-610.
Liu C-T, Raghavan S, Maruthur N, et al. "Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin." Am J Hum Genet. 2016;99(1):56-75.
Verweij N, Mateo Leach I, Isaacs A, et al. "Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram." Hum Mol Genet. 2016;25(10):2093-2103.
Lubitz SA, Brody JA, Bihlmeyer NA, et al. "Whole Exome Sequencing in Atrial Fibrillation." PLoS Genet. 2016;12(9):e1006284.
Yu B, de Vries PS, Metcalf GA, et al. "Whole genome sequence analysis of serum amino acid levels." Genome Biol. 2016;17(1):237.
Farlow JL, Robak LA, Hetrick K, et al. "Whole-Exome Sequencing in Familial Parkinson Disease." JAMA Neurol. 2016;73(1):68-75.
Michos ED, Misialek JR, Selvin E, Folsom AR, Pankow JS, Post WS. "25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms and incident coronary heart disease among whites and blacks: The ARIC study." Atherosclerosis. 2015;241(1):12-7.
Lutsey PL, Eckfeldt JH, Ogagarue ER, Folsom AR, Michos ED. "The 25-hydroxyvitamin D3 C-3 epimer: distribution, correlates, and reclassification of 25-hydroxyvitamin D status in the population-based Atherosclerosis Risk in Communities Study (ARIC)." Clin Chim Acta. 2015;442:75-81.
Amendola LM, Dorschner MO, Robertson PD, et al. "Actionable exomic incidental findings in 6503 participants: challenges of variant classification." Genome Res. 2015;25(3):305-15.
Tandon A, Chen CJ, Penman A, et al. "African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans." Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005.
Gonçalves A, Claggett B, Jhund PS, et al. "Alcohol consumption and risk of heart failure: the Atherosclerosis Risk in Communities Study." Eur Heart J. 2015;36(15):939-45.
Folsom AR, Olson NC, Lutsey PL, Roetker NS. "American Heart Association's Life's Simple 7 and incidence of venous thromboembolism." Am J Hematol. 2015;90(5):E92.
Folsom AR, Shah AM, Lutsey PL, et al. "American Heart Association's Life's Simple 7: Avoiding Heart Failure and Preserving Cardiac Structure and Function." Am J Med. 2015;128(9):970-6.e2.
C Quarta C, Buxbaum JN, Shah AM, et al. "The amyloidogenic V122I transthyretin variant in elderly black Americans." N Engl J Med. 2015;372(1):21-9.
Gross AL, Power MC, Albert MS, et al. "Application of Latent Variable Methods to the Study of Cognitive Decline When Tests Change over Time." Epidemiology. 2015;26(6):878-87.
Zhou L, Stearns SC, Thudium EM, Alburikan KA. "Assessing Medicare Part D claim completeness using medication self-reports: the role of veteran status and Generic Drug Discount Programs." Med Care. 2015;53(5):463-70.
Corrales-Medina VF, Alvarez KN, Weissfeld LA, et al. "Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease." JAMA. 2015;313(3):264-74.
Grubbs V, Vittinghoff E, Beck JD, et al. "Association Between Periodontal Disease and Kidney Function Decline in African Americans: The Jackson Heart Study." J Periodontol. 2015;86(10):1126-32.
Chauhan G, Adams HHH, Bis JC, et al. "Association of Alzheimer's disease GWAS loci with MRI markers of brain aging." Neurobiol Aging. 2015;36(4):1765.e7-1765.e16.
Di Angelantonio E, Kaptoge S, Wormser D, et al. "Association of Cardiometabolic Multimorbidity With Mortality." JAMA. 2015;314(1):52-60.
Haring B, Misialek JR, Rebholz CM, Petruski-Ivleva N, Gottesman RF, Mosley TH. "Association of Dietary Protein Consumption With Incident Silent Cerebral Infarcts and Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 2015;46(12):3443-50.
Schick UM, Auer PL, Bis JC, et al. "Association of exome sequences with plasma C-reactive protein levels in >9000 participants." Hum Mol Genet. 2015;24(2):559-71.
Kim Y, Matsushita K, Sang Y, et al. "Association of high-sensitivity cardiac troponin T and natriuretic peptide with incident ESRD: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(4):550-8.
Brown CH, Sharrett ARichey, Coresh JJ, et al. "Association of hospitalization with long-term cognitive and brain MRI changes in the ARIC cohort." Neurology. 2015;84(14):1443-53.
Huang M, Matsushita K, Sang Y, Ballew SH, Astor BC. "Association of kidney function and albuminuria with prevalent and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(1):58-66.
Lazo M, Rubin J, Clark JM, et al. "The association of liver enzymes with biomarkers of subclinical myocardial damage and structural heart disease." J Hepatol. 2015;62(4):841-7.
Ashar FN, Moes A, Moore AZ, et al. "Association of mitochondrial DNA levels with frailty and all-cause mortality." J Mol Med (Berl). 2015;93(2):177-186.
Rebholz CM, Astor BC, Grams ME, et al. "Association of plasma levels of soluble receptor for advanced glycation end products and risk of kidney disease: the Atherosclerosis Risk in Communities study." Nephrol Dial Transplant. 2015;30(1):77-83.
Appiah D, Schreiner PJ, Maclehose RF. "Association of Plasma γ' Fibrinogen With Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb Vasc Biol. 2015;35(12):2700-6.
Yu B, Li AH, Muzny D, et al. "Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease." Circ Cardiovasc Genet. 2015;8(2):351-5.
Misialek JR, Bekwelem W, Chen LYee, et al. "Association of White Blood Cell Count and Differential with the Incidence of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study." PLoS One. 2015;10(8):e0136219.
Caughey MC, Loehr LR, Cheng S, Solomon SD, Avery C. "Associations between echocardiographic arterial compliance and incident cardiovascular disease in blacks: the ARIC study." Am J Hypertens. 2015;28(1):81-8.
Takiar R, Lutsey PL, Zhao D, et al. "The associations of 25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms, and race with risk of incident fracture-related hospitalization: Twenty-year follow-up in a bi-ethnic cohort (the ARIC Study)." Bone. 2015;78:94-101.
Soliman EZ, Norby FL, O'Neal WT, et al. "Atrial Fibrillation and Risk of ST-Segment-Elevation Versus Non-ST-Segment-Elevation Myocardial Infarction: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2015;131(21):1843-50.
Waks JW, Soliman EZ, Henrikson CA, et al. "Beat-to-beat spatiotemporal variability in the T vector is associated with sudden cardiac death in participants without left ventricular hypertrophy: the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2015;4(1):e001357.
Akinkugbe AA, Saraiya VM, Preisser JS, Offenbacher S. "Bias in estimating the cross-sectional smoking, alcohol, obesity and diabetes associations with moderate-severe periodontitis in the Atherosclerosis Risk in Communities study: comparison of full versus partial-mouth estimates." J Clin Periodontol. 2015;42(7):609-21.
Gottesman RF, Fornage M, Knopman DS. "Brain Aging in African-Americans: The Atherosclerosis Risk in Communities (ARIC) Experience." Curr Alzheimer Res. 2015;12(7):607-13.
Skali H, Shah A, Gupta DK, et al. "Cardiac structure and function across the glycemic spectrum in elderly men and women free of prevalent heart disease: the Atherosclerosis Risk In the Community study." Circ Heart Fail. 2015;8(3):448-54.
Rebholz CM, Grams ME, Matsushita K, et al. "Change in Multiple Filtration Markers and Subsequent Risk of Cardiovascular Disease and Mortality." Clin J Am Soc Nephrol. 2015;10(6):941-8.
Rebholz CM, Grams ME, Matsushita K, Selvin E. "Change in novel filtration markers and risk of ESRD." Am J Kidney Dis. 2015;66(1):47-54.
Folsom AR, Yao L, Alonso A, et al. "Circulating Biomarkers and Abdominal Aortic Aneurysm Incidence: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2015;132(7):578-85.
Watkin LB, Jessen B, Wiszniewski W, et al. "COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis." Nat Genet. 2015;47(6):654-60.
Polfus LM, Gibbs RA. "Coronary heart disease and genetic variants with low phospholipase A2 activity." N Engl J Med. 2015;372(3):295-6.
White IR. "Covariate-adjusted measures of discrimination for survival data." Biom J. 2015;57(4):592-613.
Butler KR, Penman AD, Minor DS. "Determinants of pulse pressure and annual rates of change in the Atherosclerosis Risk in Communities study." J Hypertens. 2015;33(12):2463-70.
Rebholz CM, Coresh JJ, Grams ME, Steffen LM, Anderson CAM, Appel LJ. "Dietary Acid Load and Incident Chronic Kidney Disease: Results from the ARIC Study." Am J Nephrol. 2015;42(6):427-35.
Smith CE, Follis JL, Nettleton JA, et al. "Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium." Mol Nutr Food Res. 2015;59(7):1373-83.
Salfati E, Morrison AC, Boerwinkle E. "Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC)." PLoS One. 2015;10(7):e0133031.
Joshi PK, Esko T, Mattsson H, et al. "Directional dominance on stature and cognition in diverse human populations." Nature. 2015;523(7561):459-462.
Bis JC, Sitlani C, Irvin R, et al. "Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium." PLoS One. 2015;10(10):e0140496.
Wei GS, Coady SA, Reis JP, et al. "Duration and Degree of Weight Gain and Incident Diabetes in Younger Versus Middle-Aged Black and White Adults: ARIC, CARDIA, and the Framingham Heart Study." Diabetes Care. 2015;38(11):2042-9.
Kamel H, O'Neal WT, Okin PM, Loehr LR, Alonso A. "Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study." Ann Neurol. 2015;78(5):670-8.
Rautaharju PM, Zhang Z-M, Haisty WK, Kucharska-Newton AMaria, Rosamond WD. "Electrocardiographic repolarization-related predictors of coronary heart disease and sudden cardiac deaths in men and women with cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study." J Electrocardiol. 2015;48(1):101-11.
Miedema MD, Norby FL, Blaha MJ, Virani SS, Coresh JJ, Ballantyne CM. "Eligibility for statin therapy according to new cholesterol guidelines and prevalent use of medication to lower lipid levels in an older US Cohort: the Atherosclerosis Risk in Communities Study Cohort." JAMA Intern Med. 2015;175(1):138-40.
Srinath R, Golden SHill, Carson KA. "Endogenous testosterone and its relationship to preclinical and clinical measures of cardiovascular disease in the atherosclerosis risk in communities study." J Clin Endocrinol Metab. 2015;100(4):1602-8.
Demerath EW, Guan W, Grove ML, et al. "Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci." Hum Mol Genet. 2015;24(15):4464-79.
Aslibekyan S, Demerath EW, Mendelson M, et al. "Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference." Obesity (Silver Spring). 2015;23(7):1493-501.
Matsushita K, Coresh JJ, Sang Y, et al. "Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data." Lancet Diabetes Endocrinol. 2015;3(7):514-25.
Gonzaga-Jauregui C, Harel T, Gambin T, et al. "Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy." Cell Rep. 2015;12(7):1169-83.
Do R, Stitziel NO, Won H-H, et al. "Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction." Nature. 2015;518(7537):102-6.
Beck TF, Campeau PM, Jhangiani SN, et al. "FBN1 contributing to familial congenital diaphragmatic hernia." Am J Med Genet A. 2015;167A(4):831-6.
Selvin E, Rawlings AM, Lutsey PL, Maruthur N, Pankow JS, Steffes M. "Fructosamine and Glycated Albumin and the Risk of Cardiovascular Outcomes and Death." Circulation. 2015;132(4):269-77.
Nettleton JA, Follis JL, Ngwa JS, et al. "Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry." Hum Mol Genet. 2015;24(16):4728-38.
Tang W, Cushman M, Green D, et al. "Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans." Am J Hematol. 2015;90(6):534-40.
Karaca E, Harel T, Pehlivan D, et al. "Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease." Neuron. 2015;88(3):499-513.
Weng L-C, Cushman M, Pankow JS, Basu S, Boerwinkle E, Folsom AR. "A genetic association study of activated partial thromboplastin time in European Americans and African Americans: the ARIC Study." Hum Mol Genet. 2015;24(8):2401-8.