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ARIC Publications

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Yaghootkar H, Scott RA, White CC, et al. "Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes." Diabetes. 2014;63(12):4369-77.
Yaghootkar H, Lamina C, Scott RA, et al. "Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes." Diabetes. 2013;62(10):3589-98.
Yamagishi K, Nettleton JA, Folsom AR. "Plasma fatty acid composition and incident heart failure in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2008;156(5):965-74.
Yamagishi K, Folsom AR. "Plasma fatty acid composition and incident ischemic stroke in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Cerebrovasc Dis. 2013;36(1):38-46.
Yamagishi K, Folsom AR, Rosamond WD, Boerwinkle E. "A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study." Eur Heart J. 2009;30(10):1222-8.
Yamagishi K, Aleksic N, Hannan PJ, Folsom AR. "Coagulation factors II, V, IX, X, XI, and XII, plasminogen, and alpha-2 antiplasmin and risk of coronary heart disease." J Atheroscler Thromb. 2010;17(4):402-9.
Yamagishi K, Cushman M, Heckbert SR, Tsai MY, Folsom AR. "Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study." Br J Haematol. 2009;145(2):221-6.
Yan Y, North KE, Ballantyne CM, et al. "Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study." Diabetes. 2009;58(1):285-9.
Yan Y, Klein R, Heiss G, et al. "The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study." BMC Endocr Disord. 2010;10:9.
Yang J, Loos RJF, Powell JE, et al. "FTO genotype is associated with phenotypic variability of body mass index." Nature. 2012;490(7419):267-72.
Yang C, Kwak L, Ballew SH, et al. "Retinal microvascular findings and risk of incident peripheral artery disease: An analysis from the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2020;294:62-71.
Yang EY, Nambi V, Tang Z, et al. "Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study." J Am Coll Cardiol. 2009;54(25):2388-95.
Yang EY, Chambless L, A Sharrett R, et al. "Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2012;43(1):103-8.
Yang C, Kwak L, Ballew SH, et al. "Kidney function, bone-mineral metabolism markers, and future risk of peripheral artery disease." Atherosclerosis. 2017;267:167-174.
Yano Y, Griswold M, Wang W, et al. "Long-Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study." J Am Heart Assoc. 2018;7(15):e009578.
Yao L, Folsom AR, Alonso A, et al. "Association of carotid atherosclerosis and stiffness with abdominal aortic aneurysm: The atherosclerosis risk in communities (ARIC) study." Atherosclerosis. 2018;270:110-116.
Yao L, Folsom AR, Pankow JS, et al. "Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
Yatsuya H, Folsom AR. "Risk of incident cardiovascular disease among users of smokeless tobacco in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2010;172(5):600-5.
Yatsuya H, Folsom AR, Yamagishi K, North KE, Brancati FL, Stevens J. "Race- and sex-specific associations of obesity measures with ischemic stroke incidence in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2010;41(3):417-25.
Yatsuya H, Yamagishi K, North KE, Brancati FL, Stevens J, Folsom AR. "Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study." J Epidemiol. 2010;20(5):347-54.
Yatsuya H, Folsom AR, Wong TY, Klein R, Klein BEK, A Sharrett R. "Retinal microvascular abnormalities and risk of lacunar stroke: Atherosclerosis Risk in Communities Study." Stroke. 2010;41(7):1349-55.
Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM. "Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study." Hypertension. 2011;57(2):167-73.
Yazdani A, Yazdani A, Samiei A. "Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data." J Biomed Inform. 2016;60:114-9.
Yazdani A, Yazdani A, Saniei A. "A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels." Metabolomics. 2016;12:104.
Yazdani A, Yazdani A, Liu X. "Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis." Genet Epidemiol. 2016;40(6):486-91.
Yazdani A, Yazdani A. "Rare variants analysis using penalization methods for whole genome sequence data." BMC Bioinformatics. 2015;16:405.
Yazdani A, Yazdani A, Samiei A. "Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study." J Biomed Inform. 2016;63:337-343.
Yazdani A, Yazdani A. "A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate." OMICS. 2016;20(8):480-4.
Yeap BBeng, Marriott RJames, Adams RJ, et al. "Androgens In Men Study (AIMS): protocol for meta-analyses of individual participant data investigating associations of androgens with health outcomes in men." BMJ Open. 2020;10(5):e034777.
Yee SWah, Stecula A, Chien H-C, et al. "Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies." PLoS Genet. 2019;15(9):e1008208.
Yeh H-C, Punjabi NM, Wang N-Y, Pankow JS, Duncan BB, Brancati FL. "Vital capacity as a predictor of incident type 2 diabetes: the Atherosclerosis Risk in Communities study." Diabetes Care. 2005;28(6):1472-9.
Yeh H-C, Duncan BB, Schmidt M I, Wang N-Y, Brancati FL. "Smoking, smoking cessation, and risk for type 2 diabetes mellitus: a cohort study." Ann Intern Med. 2010;152(1):10-7.
Yeh H-C, Punjabi NM, Wang N-Y, et al. "Cross-sectional and prospective study of lung function in adults with type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Diabetes Care. 2008;31(4):741-6.
Yende S, Alvarez K, Loehr L, et al. "Epidemiology and long-term clinical and biologic risk factors for pneumonia in community-dwelling older Americans: analysis of three cohorts." Chest. 2013;144(3):1008-1017.
Yeung EH, Saudek CD, Jahren HA, et al. "Evaluation of a novel isotope biomarker for dietary consumption of sweets." Am J Epidemiol. 2010;172(9):1045-52.
Yeung EH, Pankow JS, Astor BC, Powe NR, Saudek CD, Kao LWH. "Increased risk of type 2 diabetes from a family history of coronary heart disease and type 2 diabetes." Diabetes Care. 2007;30(1):154-6.
Yi S-Y, Steffen LM, Lutsey PL, Cushman M, Folsom AR. "Contrasting Associations of Prudent and Western Dietary Patterns with Risk of Developing Venous Thromboembolism." Am J Med. 2021.
Yoneyama S, Yao J, Guo X, et al. "Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations." Int J Obes (Lond). 2017;41(2):324-331.
Yoneyama S, Guo Y, Lanktree MB, et al. "Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations." Hum Mol Genet. 2014;23(9):2498-510.
Yong F, Heiss G, Couper DJ, Meyer ML, Cheng S. "Measurement Repeatability of Central and Peripheral Blood Pressures: The ARIC Study." Am J Hypertens. 2017;30(10):978-984.
Young SE, Mainous AG, Carnemolla M. "Hyperinsulinemia and cognitive decline in a middle-aged cohort." Diabetes Care. 2006;29(12):2688-93.
Young KL, Graff M, Fernández-Rhodes L. "Genetics of Obesity in Diverse Populations." Curr Diab Rep. 2018;18(12):145.
Yu B, Flexeder C, McGarrah RW, et al. "Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population." Metabolites. 2019;9(4).
Yu B, Zheng Y, Alexander D, Manolio TA, Alonso A, Nettleton JA. "Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study." Genet Epidemiol. 2013;37(8):840-5.
Yu B, de Vries PS, Metcalf GA, et al. "Whole genome sequence analysis of serum amino acid levels." Genome Biol. 2016;17(1):237.
Yu Z, Rebholz CM, Wong E, Chen Y, Matsushita K, Coresh JJ. "Association Between Hypertension and Kidney Function Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2019;74(3):310-319.
Yu B, Pulit SL, Hwang S-J, et al. "Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk." Circ Cardiovasc Genet. 2016;9(1):64-70.
Yu B, Zheng Y, Nettleton JA, Alexander D, Coresh JJ. "Serum metabolomic profiling and incident CKD among African Americans." Clin J Am Soc Nephrol. 2014;9(8):1410-7.
Yu Z, Grams ME, Ndumele CE, et al. "Association Between Midlife Obesity and Kidney Function Trajectories: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2020.
Yu B, Li AH, Metcalf GA, et al. "Loss-of-function variants influence the human serum metabolome." Sci Adv. 2016;2(8):e1600800.
Yu B, Zheng Y, Alexander D, Morrison AC, Coresh JJ. "Genetic determinants influencing human serum metabolome among African Americans." PLoS Genet. 2014;10(3):e1004212.
Yu B, Heiss G, Alexander D, Grams ME. "Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 2016;183(7):650-6.
Yu F, Lu J, Liu X, et al. "Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions." PLoS One. 2015;10(3):e0121644.
Yu B, Zanetti KA, Temprosa M, et al. "The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies." Am J Epidemiol. 2019;188(6):991-1012.
Yu B, Roberts MB, Raffield LM, et al. "Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure." J Am Coll Cardiol. 2021;78(1):42-52.
Yu B, Barbalic M, Brautbar A, et al. "Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies." Circ Cardiovasc Genet. 2013;6(1):82-8.
Yu Z, Coresh JJ, Qi G, et al. "A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure." Kidney Int. 2020;98(3):708-716.
Yu B, Li AH, Muzny D, et al. "Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease." Circ Cardiovasc Genet. 2015;8(2):351-5.