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ARIC Publications

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Morrison AC, Huang Z, Yu B, et al. "Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits." Am J Hum Genet. 2017;100(2):205-215.
van Setten J, Brody JA, Jamshidi Y, et al. "PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity." Nat Commun. 2018;9(1):2904.
West NA, Tingle JV, Simino J, Selvin E, Bressler J. "The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity." Alzheimer Dis Assoc Disord. 2018;32(2):131-136.
Loehr LR, Rosamond WD, Poole C, et al. "The potentially modifiable burden of incident heart failure due to obesity: the atherosclerosis risk in communities study." Am J Epidemiol. 2010;172(7):781-9.
Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM. "Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study." Hypertension. 2011;57(2):167-73.
Jones SB, Sen S, Lakshminarayan K, Rosamond WD. "Poststroke outcomes vary by pathogenic stroke subtype in the Atherosclerosis Risk in Communities Study." Stroke. 2013;44(8):2307-10.
Brown SA, Chambless LE, Sharrett AR, Gotto AM, Patsch W. "Postprandial lipemia: reliability in an epidemiologic field study." Am J Epidemiol. 1992;136(5):538-45.
Kats D, Sharrett ARichey, Ginsberg HN, Nambi V, Ballantyne CM, Hoogeveen RC. "Postprandial lipemia and the risk of coronary heart disease and stroke: the Atherosclerosis Risk in Communities (ARIC) Study." BMJ Open Diabetes Res Care. 2017;5(1):e000335.
Dumitrescu L, Carty CL, Franceschini N, et al. "Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study." Ann Hum Genet. 2013;77(5):416-25.
Zhou Z, Yu F, Buchanan A, et al. "Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts." PLoS One. 2014;9(1):e84810.
Bush M, Sturmer T, Stearns SC, Simpson RJ, M Brookhart A, Rosamond WD. "Position matters: Validation of medicare hospital claims for myocardial infarction against medical record review in the atherosclerosis risk in communities study." Pharmacoepidemiol Drug Saf. 2018;27(10):1085-1091.
Liao D, Evans GW, Chambless LE, et al. "Population-based study of heart rate variability and prevalent myocardial infarction. The Atherosclerosis Risk in Communities Study." J Electrocardiol. 1996;29(3):189-98.
Seplyarskiy VB, Soldatov RA, Koch E, et al. "Population sequencing data reveal a compendium of mutational processes in the human germ line." Science. 2021;373(6558):1030-1035.
Yu F, Lu J, Liu X, et al. "Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions." PLoS One. 2015;10(3):e0121644.
Folsom AR, Wu KK, Davis CE, Conlan MG, Sorlie PD, Szklo M. "Population correlates of plasma fibrinogen and factor VII, putative cardiovascular risk factors." Atherosclerosis. 1991;91(3):191-205.
Avery CL, Loehr LR, Baggett C, et al. "The population burden of heart failure attributable to modifiable risk factors: the ARIC (Atherosclerosis Risk in Communities) study." J Am Coll Cardiol. 2012;60(17):1640-6.
Nieto FJ, Alonso J, Chambless LE, et al. "Population awareness and control of hypertension and hypercholesterolemia. The Atherosclerosis Risk in Communities study." Arch Intern Med. 1995;155(7):677-84.
Bash LD, Selvin E, Steffes M, Coresh J, Astor BC. "Poor glycemic control in diabetes and the risk of incident chronic kidney disease even in the absence of albuminuria and retinopathy: Atherosclerosis Risk in Communities (ARIC) Study." Arch Intern Med. 2008;168(22):2440-7.
Dearborn JL, Qiao Y, Guallar E, Steffen LM, Gottesman RF, Zhang Y. "Polyunsaturated fats, carbohydrates and carotid disease: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI study." Atherosclerosis. 2016;251:361-366.
Iber C, Redline S, Kaplan Gilpin AM, et al. "Polysomnography performed in the unattended home versus the attended laboratory setting--Sleep Heart Health Study methodology." Sleep. 2004;27(3):536-40.
Redline S, Min NI, Shahar E, Rapoport D, O'Connor G. "Polysomnographic predictors of blood pressure and hypertension: is one index best?" Sleep. 2005;28(9):1122-30.
Winkelman JW, Redline S, Baldwin CM, Resnick HE, Newman AB, Gottlieb DJ. "Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health Study." Sleep. 2009;32(6):772-8.
Iso H, Harada S, Shimamoto T, et al. "Polymorphism of the apolipoprotein B gene and blood lipid concentrations in Japanese and Caucasian population samples." Atherosclerosis. 1996;126(2):233-41.
Surguchov AP, Page GP, Smith L, Patsch W, Boerwinkle E. "Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia." Arterioscler Thromb Vasc Biol. 1996;16(8):941-7.
Gaubatz JW, Ghanem KI, Guevara J, Nava ML, Patsch W, Morrisett JD. "Polymorphic forms of human apolipoprotein[a]: inheritance and relationship of their molecular weights to plasma levels of lipoprotein[a]." J Lipid Res. 1990;31(4):603-13.
Hu X, Qiao D, Kim W, et al. "Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program." Am J Hum Genet. 2022;109(5):857-870.
Yu Z, Jin J, Tin A, et al. "Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases." J Am Soc Nephrol. 2021.
Thomas EA, Enduru N, Tin A, et al. "Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke." J Am Heart Assoc. 2022;11(15):e025703.
Rywik SL, Davis CE, Pajak A, et al. "Poland and U.S. collaborative study on cardiovascular epidemiology hypertension in the community: prevalence, awareness, treatment, and control of hypertension in the Pol-MONICA Project and the U.S. Atherosclerosis Risk in Communities Study." Ann Epidemiol. 1998;8(1):3-13.
Broda G, Davis CE, Pajak A, et al. "Poland and United States Collaborative Study on Cardiovascular Epidemiology. A comparison of HDL cholesterol and its subfractions in populations covered by the United States Atherosclerosis Risk in Communities Study and the Pol-MONICA Project." Arterioscler Thromb Vasc Biol. 1996;16(2):339-49.
White J, Beck CR, Harel T, et al. "POGZ truncating alleles cause syndromic intellectual disability." Genome Med. 2016;8(1):3.
Raynor LA, Pankow JS, Rasmussen-Torvik LJ, Tang W, Prizment A, Couper DJ. "Pleiotropy and pathway analyses of genetic variants associated with both type 2 diabetes and prostate cancer." Int J Mol Epidemiol Genet. 2013;4(1):49-60.
Ligthart S, de Vries PS, Uitterlinden AG, Hofman A, Franco OH, Chasman DI. "Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein." PLoS One. 2015;10(3):e0118859.
Kraja AT, Chasman DI, North KE, et al. "Pleiotropic genes for metabolic syndrome and inflammation." Mol Genet Metab. 2014;112(4):317-38.
Weng L-C, Guan W, Steffen LM, et al. "Pleiotropic effects of n-6 and n-3 fatty acid-related genetic variants on circulating hemostatic variables." Thromb Res. 2018;168:53-59.
Cheng I, Kocarnik JM, Dumitrescu L, et al. "Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia." Gut. 2014;63(5):800-7.
S Park L, Fesinmeyer MD, Timofeeva M, et al. "Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia." J Natl Cancer Inst. 2014;106(4):dju061.
van der Lee SJ, Holstege H, Wong THang, et al. "PLD3 variants in population studies." Nature. 2015;520(7545):E2-3.
Eicher JD, Chami N, Kacprowski T, et al. "Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals." Am J Hum Genet. 2016;99(1):40-55.
Aleksic N, Juneja H, Folsom AR, et al. "Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study." Circulation. 2000;102(16):1901-5.
Greenberg KI, McAdams-Demarco MA, Köttgen A, Appel LJ, Coresh JJ. "Plasma Urate and Risk of a Hospital Stay with AKI: The Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(5):776-83.
Chen H, Mosley TH, Alonso A, Huang X. "Plasma urate and Parkinson's disease in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2009;169(9):1064-9.
Berger D, Folsom AR, Schreiner PJ, et al. "Plasma total testosterone and risk of incident atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study." Maturitas. 2019;125:5-10.
Zhang J, Dutta D, Köttgen A, et al. "Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies." Nat Genet. 2022;54(5):593-602.
Lindbohm JV, Mars N, Walker KA, et al. "Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies." Alzheimers Dement. 2021.
Li D, Misialek JR, Boerwinkle E, et al. "Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS)." Alzheimers Dement (Amst). 2016;3:73-82.
Li D, Misialek JR, Jing M, et al. "Plasma phospholipid very-long-chain SFAs in midlife and 20-year cognitive change in the Atherosclerosis Risk in Communities (ARIC): a cohort study." Am J Clin Nutr. 2020;111(6):1252-1258.
Folsom AR, Ma J, Eckfeldt JH, Shahar E, Wu KK. "Plasma phospholipid fatty acid composition and factor VII coagulant activity." Atherosclerosis. 1994;111(2):199-207.
Beydoun MA, Kaufman JS, Satia JA, Rosamond W, Folsom AR. "Plasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2007;85(4):1103-11.
Granot-Hershkovitz E, He S, Bressler J, et al. "Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition." Alzheimers Dement. 2022.
Li D, Misialek JR, Jack CR, et al. "Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS)." Int J Mol Sci. 2019;20(7).
Hoogeveen RC, Morrison A, Boerwinkle E, et al. "Plasma MCP-1 level and risk for peripheral arterial disease and incident coronary heart disease: Atherosclerosis Risk in Communities study." Atherosclerosis. 2005;183(2):301-7.
Muntner P, Coresh J, Smith JC, Eckfeldt J, Klag MJ. "Plasma lipids and risk of developing renal dysfunction: the atherosclerosis risk in communities study." Kidney Int. 2000;58(1):293-301.
Shahar E, Chambless LE, Rosamond WD, et al. "Plasma lipid profile and incident ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2003;34(3):623-31.
Brown SA, Hutchinson R, Morrisett J, et al. "Plasma lipid, lipoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb. 1993;13(8):1139-58.
Juraschek SP, Bower JK, Selvin E, Shantha GPalamaner, Hoogeveen RC, Ballantyne CM. "Plasma lactate and incident hypertension in the atherosclerosis risk in communities study." Am J Hypertens. 2015;28(2):216-24.
Juraschek SP, Selvin E, Miller ER, Brancati FL. "Plasma lactate and diabetes risk in 8045 participants of the atherosclerosis risk in communities study." Ann Epidemiol. 2013;23(12):791-796.e4.
Voight BF, Peloso GM, Orho-Melander M, et al. "Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study." Lancet. 2012;380(9841):572-80.
Rebholz CM, Selvin E, Liang M, et al. "Plasma galectin-3 levels are associated with the risk of incident chronic kidney disease." Kidney Int. 2018;93(1):252-259.
Oyenuga A, Folsom AR, Fashanu O, Aguilar D. "Plasma Galectin-3 and Sonographic Measures of Carotid Atherosclerosis in the Atherosclerosis Risk in Communities Study." Angiology. 2019;70(1):47-55.
Iso H, Folsom AR, Sato S, et al. "Plasma fibrinogen and its correlates in Japanese and US population samples." Arterioscler Thromb. 1993;13(6):783-90.
Folsom AR, Peacock JM, Nieto FJ, et al. "Plasma fibrinogen and incident hypertension in the Atherosclerosis Risk in Communities (ARIC) Study." J Hypertens. 1998;16(11):1579-83.
Ma J, Folsom AR, Shahar E, Eckfeldt JH. "Plasma fatty acid composition as an indicator of habitual dietary fat intake in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Am J Clin Nutr. 1995;62(3):564-71.
Yamagishi K, Folsom AR. "Plasma fatty acid composition and incident ischemic stroke in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Cerebrovasc Dis. 2013;36(1):38-46.
Yamagishi K, Nettleton JA, Folsom AR. "Plasma fatty acid composition and incident heart failure in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2008;156(5):965-74.
Wang L, Folsom AR, Zheng Z-jie, Pankow JS, Eckfeldt JH. "Plasma fatty acid composition and incidence of diabetes in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2003;78(1):91-8.
Wang L, Folsom AR, Eckfeldt JH. "Plasma fatty acid composition and incidence of coronary heart disease in middle aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Nutr Metab Cardiovasc Dis. 2003;13(5):256-66.
Zheng ZJ, Folsom AR, Ma J, Arnett DK, McGovern PG, Eckfeldt JH. "Plasma fatty acid composition and 6-year incidence of hypertension in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1999;150(5):492-500.
Jia X, Sun C, Tang O, et al. "Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women." J Clin Endocrinol Metab. 2020;105(12).
Folsom AR, Gottesman RF, Appiah D, Shahar E. "Plasma d-Dimer and Incident Ischemic Stroke and Coronary Heart Disease: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(1):18-23.
Prizment AE, Folsom AR, Dreyfus J, et al. "Plasma C-reactive protein, genetic risk score, and risk of common cancers in the Atherosclerosis Risk in Communities study." Cancer Causes Control. 2013;24(12):2077-87.
Folsom AR, Tang W, Basu S, Misialek JR, Couper DJ, Heckbert SR. "Plasma Concentrations of High Molecular Weight Kininogen and Prekallikrein and Venous Thromboembolism Incidence in the General Population." Thromb Haemost. 2019;119(5):834-843.
Damotte V, van der Lee SJ, Chouraki V, et al. "Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants." Alzheimers Dement. 2021.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Coresh JJ. "Plant-Based Diets Are Associated With a Lower Risk of Incident Cardiovascular Disease, Cardiovascular Disease Mortality, and All-Cause Mortality in a General Population of Middle-Aged Adults." J Am Heart Assoc. 2019;8(16):e012865.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Grams ME, Coresh JJ. "Plant-Based Diets and Incident CKD and Kidney Function." Clin J Am Soc Nephrol. 2019;14(5):682-691.
Giri TK, Tollefsen DM. "Placental dermatan sulfate: isolation, anticoagulant activity, and association with heparin cofactor II." Blood. 2006;107(7):2753-8.
Burke BTeevan, Köttgen A, Law A, et al. "Physical Function, Hyperuricemia, and Gout in Older Adults." Arthritis Care Res (Hoboken). 2015;67(12):1730-8.
Hu X, Mok Y, Ding N, et al. "Physical Function and Subsequent Risk of Cardiovascular Events in Older Adults: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(17):e025780.
Ducca EL, Gomez GT, Palta P, et al. "Physical Frailty and Brain White Matter Abnormalities: The ARIC Study." J Gerontol A Biol Sci Med Sci. 2022.
Xu J, Liu G, Hegde SM, et al. "Physical Activity-Related Metabolites Are Associated with Mortality: Findings from the Atherosclerosis Risk in Communities (ARIC) Study." Metabolites. 2021;11(1).

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