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ARIC Publications

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Hyun N, Couper DJ, Zeng D. "A semiparametric Gumbel regression model for analyzing longitudinal data with non-normal tails." Stat Med. 2022;41(4):736-750.
Hyacinth HI, Franceschini N, Seals SR, et al. "Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals." JAMA Netw Open. 2021;4(1):e2030435.
Hwang SJ, Ballantyne CM, Sharrett AR, et al. "Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study." Circulation. 1997;96(12):4219-25.
Huxley RR, Alonso A, Lopez FL, et al. "Type 2 diabetes, glucose homeostasis and incident atrial fibrillation: the Atherosclerosis Risk in Communities study." Heart. 2012;98(2):133-8.
Huxley RR, Bell EJ, Lutsey PL, et al. "A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study." Ethn Health. 2014;19(6):601-16.
Huxley RR, Lopez FL, Maclehose RF, et al. "Novel association between plasma matrix metalloproteinase-9 and risk of incident atrial fibrillation in a case-cohort study: the Atherosclerosis Risk in Communities study." PLoS One. 2013;8(3):e59052.
Huxley RR, Lopez FL, Folsom AR, et al. "Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2011;123(14):1501-8.
Huxley RR, Misialek JR, Agarwal SK, Loehr LR, Soliman EZ, Chen LYee. "Physical activity, obesity, weight change, and risk of atrial fibrillation: the Atherosclerosis Risk in Communities study." Circ Arrhythm Electrophysiol. 2014;7(4):620-5.
Huxley RR, Yatsuya H, Lutsey PL, Woodward M, Alonso A, Folsom AR. "Impact of age at smoking initiation, dosage, and time since quitting on cardiovascular disease in african americans and whites: the atherosclerosis risk in communities study." Am J Epidemiol. 2012;175(8):816-26.
Hutchinson RG, Watson RL, Davis CE, et al. "Racial differences in risk factors for atherosclerosis. The ARIC Study. Atherosclerosis Risk in Communities." Angiology. 1997;48(4):279-90.
Hussain A, Tang O, Sun C, et al. "Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2021;146:15-21.
Hussain A, Sun C, Selvin E, et al. "Triglyceride-rich lipoproteins, apolipoprotein C-III, angiopoietin-like protein 3, and cardiovascular events in older adults: Atherosclerosis Risk in Communities (ARIC) study." Eur J Prev Cardiol. 2021.
Hussain A, Sun W, Deswal A, et al. "Association of NT-ProBNP, Blood Pressure, and Cardiovascular Events: The ARIC Study." J Am Coll Cardiol. 2021;77(5):559-571.
Hurwitz LM, Joshu CE, Barber JR, et al. "Aspirin and Non-Aspirin NSAID Use and Prostate Cancer Incidence, Mortality, and Case Fatality in the Atherosclerosis Risk in Communities Study." Cancer Epidemiol Biomarkers Prev. 2019;28(3):563-569.
Hunt KJ, Evans GW, Folsom AR, et al. "Acoustic shadowing on B-mode ultrasound of the carotid artery predicts ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2001;32(5):1120-6.
Hunt KJ, Pankow JS, Offenbacher S, et al. "B-mode ultrasound-detected carotid artery lesions with and without acoustic shadowing and their association with markers of inflammation and endothelial activation: the atherosclerosis risk in communities study." Atherosclerosis. 2002;162(1):145-55.
Hunt KJ, Sharrett AR, Chambless LE, Folsom AR, Evans GW, Heiss G. "Acoustic shadowing on B-mode ultrasound of the carotid artery predicts CHD." Ultrasound Med Biol. 2001;27(3):357-65.
Hunsberger S, Sorlie P, Geller NL. "Stochastic curtailing and conditional power in matched case-control studies." Stat Med. 1994;13(5-7):663-70.
Hung C-L, Gonçalves A, Shah AM, Cheng S, Kitzman D. "Age- and Sex-Related Influences on Left Ventricular Mechanics in Elderly Individuals Free of Prevalent Heart Failure: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Cardiovasc Imaging. 2017;10(1).
Hui X, Matsushita K, Sang Y, Ballew SH, Fulop T. "CKD and cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study: interactions with age, sex, and race." Am J Kidney Dis. 2013;62(4):691-702.
Hughes TM, Wagenknecht LE, Craft S, et al. "Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study." Neurology. 2018;90(14):e1248-e1256.
Huffman JE, de Vries PS, Morrison AC, et al. "Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF." Blood. 2015;126(11):e19-29.
Huffman JE, Albrecht E, Teumer A, et al. "Modulation of genetic associations with serum urate levels by body-mass-index in humans." PLoS One. 2015;10(3):e0119752.
Hubbard LD, Brothers RJ, King WN, et al. "Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study." Ophthalmology. 1999;106(12):2269-80.
Huang X, Alonso A, Guo X, et al. "Statins, plasma cholesterol, and risk of Parkinson's disease: a prospective study." Mov Disord. 2015;30(4):552-9.
Huang H, Chanda P, Alonso A, Bader JS, Arking DE. "Gene-based tests of association." PLoS Genet. 2011;7(7):e1002177.
Huang J, Wang K, Wei P, et al. "FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics." Genetics. 2016;202(3):919-29.
Huang M, Matsushita K, Sang Y, Ballew SH, Astor BC. "Association of kidney function and albuminuria with prevalent and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(1):58-66.
Huang J, Sabater-Lleal M, Asselbergs FW, et al. "Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation." Blood. 2012;120(24):4873-81.
Huang J, Huffman JE, Yamakuchi M, et al. "Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2." Arterioscler Thromb Vasc Biol. 2014;34(5):1093-101.
Huang Z, Rustagi N, Veeraraghavan N, et al. "A hybrid computational strategy to address WGS variant analysis in >5000 samples." BMC Bioinformatics. 2016;17(1):361.
Huan T, Joehanes R, Song C, et al. "Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease." Nat Commun. 2019;10(1):4267.
Huan T, Nguyen S, Colicino E, et al. "Integrative analysis of clinical and epigenetic biomarkers of mortality." Aging Cell. 2022;21(6):e13608.
Hua S, Loehr LR, Tanaka H, Heiss G, Coresh JJ, Selvin E. "Ankle-brachial index and incident diabetes mellitus: the atherosclerosis risk in communities (ARIC) study." Cardiovasc Diabetol. 2016;15(1):163.
Hu Y, Stilp AM, McHugh CP, et al. "Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program." Am J Hum Genet. 2021;108(6):1165.
Hu JK, Chan KCG, Couper DJ, Breslow NE. "Estimating the hazard rate difference from case-cohort studies." Eur J Epidemiol. 2021;36(11):1129-1142.
Hu EA, Lazo M, Selvin E, et al. "Coffee consumption and liver-related hospitalizations and deaths in the ARIC study." Eur J Clin Nutr. 2019;73(8):1133-1140.
Hu Y, Haessler JW, Manansala R, et al. "Whole-Genome Sequencing Association Analyses of Stroke and Its Subtypes in Ancestrally Diverse Populations From Trans-Omics for Precision Medicine Project." Stroke. 2022;53(3):875-885.
Hu X, Qiao D, Kim W, et al. "Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program." Am J Hum Genet. 2022;109(5):857-870.
Hu EA, Steffen LM, Grams ME, Crews DC, Coresh JJ, Appel LJ. "Dietary patterns and risk of incident chronic kidney disease: the Atherosclerosis Risk in Communities study." Am J Clin Nutr. 2019;110(3):713-721.
Hu EA, Lazo M, Rosenberg SD, Grams ME, Steffen LM, Coresh JJ. "Alcohol Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities Study." J Ren Nutr. 2020;30(1):22-30.
Hu EA, Wu A, Dearborn JL, et al. "Adherence to Dietary Patterns and Risk of Incident Dementia: Findings from the Atherosclerosis Risk in Communities Study." J Alzheimers Dis. 2020;78(2):827-835.
Hu EA, Steffen LM, Coresh JJ, Appel LJ. "Adherence to the Healthy Eating Index-2015 and Other Dietary Patterns May Reduce Risk of Cardiovascular Disease, Cardiovascular Mortality, and All-Cause Mortality." J Nutr. 2020;150(2):312-321.
Hu Y-J, Berndt SI, Gustafsson S, et al. "Meta-analysis of gene-level associations for rare variants based on single-variant statistics." Am J Hum Genet. 2013;93(2):236-48.
Hu X, Mok Y, Ding N, et al. "Physical Function and Subsequent Risk of Cardiovascular Events in Older Adults: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(17):e025780.
Hu EA, Selvin E, Grams ME, Steffen LM, Coresh JJ. "Coffee Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(2):214-222.
Hsu CC, Brancati FL, Astor BC, et al. "Blood pressure, atherosclerosis, and albuminuria in 10,113 participants in the atherosclerosis risk in communities study." J Hypertens. 2009;27(2):397-409.
Hsu CC, Kao LWH, Coresh J, et al. "Apolipoprotein E and progression of chronic kidney disease." JAMA. 2005;293(23):2892-9.
Hsu CC, Kao WL, Steffes MW, et al. "Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study." BMC Med Genet. 2011;12:16.
Hsu CChia-Chuen, Bray MS, Kao LWH, Pankow JS, Boerwinkle E, Coresh J. "Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study." J Am Soc Nephrol. 2006;17(2):504-12.
Hruby A, Ngwa JS, Renstrom F, et al. "Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies." J Nutr. 2013;143(3):345-53.
Hozawa A, Billings JL, Shahar E, Ohira T, Rosamond WD, Folsom AR. "Lung function and ischemic stroke incidence: the Atherosclerosis Risk in Communities study." Chest. 2006;130(6):1642-9.
Hozawa A, Folsom AR, Ibrahim H, Nieto JF, Rosamond WD, Shahar E. "Serum uric acid and risk of ischemic stroke: the ARIC Study." Atherosclerosis. 2006;187(2):401-7.
Hozawa A, Folsom AR, A Sharrett R, Payne TJ, Chambless LE. "Does the impact of smoking on coronary heart disease differ by low-density lipoprotein cholesterol level?: the Atherosclerosis Risk in Communities (ARIC) Study." Circ J. 2006;70(9):1105-10.
Hozawa A, Folsom AR, A Sharrett R, Chambless LE. "Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: comparison of African American with white subjects--Atherosclerosis Risk in Communities Study." Arch Intern Med. 2007;167(6):573-9.
Howson JMM, Zhao W, Barnes DR, et al. "Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms." Nat Genet. 2017;49(7):1113-1119.
Howell SJ, German D, Bender A, et al. "Does Sex Modify an Association of Electrophysiological Substrate with Sudden Cardiac Death? The Atherosclerosis Risk in Communities (ARIC) Study." Cardiovasc Digit Health J. 2020;1(2):80-88.
Howard G, Wagenknecht LE, Burke GL, et al. "Cigarette smoking and progression of atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA. 1998;279(2):119-24.
Howard G, Burke GL, Szklo M, et al. "Active and passive smoking are associated with increased carotid wall thickness. The Atherosclerosis Risk in Communities Study." Arch Intern Med. 1994;154(11):1277-82.
Howard G, Burke GL, Evans GW, et al. "Relations of intimal-medial thickness among sites within the carotid artery as evaluated by B-mode ultrasound. ARIC Investigators. Atherosclerosis Risk in Communities." Stroke. 1994;25(8):1581-7.
Howard G, Manolio TA, Burke GL, Wolfson SK, O'Leary DH. "Does the association of risk factors and atherosclerosis change with age? An analysis of the combined ARIC and CHS cohorts. The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health Study (CHS) investigators." Stroke. 1997;28(9):1693-701.
Howard G, Wagenknecht LE, Cai J, Cooper L, Kraut MA, Toole JF. "Cigarette smoking and other risk factors for silent cerebral infarction in the general population." Stroke. 1998;29(5):913-7.
Howard G, Sharrett AR, Heiss G, et al. "Carotid artery intimal-medial thickness distribution in general populations as evaluated by B-mode ultrasound. ARIC Investigators." Stroke. 1993;24(9):1297-304.
Houston DK, Stevens J, Cai J, Morey MC. "Role of weight history on functional limitations and disability in late adulthood: the ARIC study." Obes Res. 2005;13(10):1793-802.
Houston DK, Stevens J, Cai J, Haines PS. "Dairy, fruit, and vegetable intakes and functional limitations and disability in a biracial cohort: the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2005;81(2):515-22.
Houston DK, Cai J, Stevens J. "Overweight and obesity in young and middle age and early retirement: the ARIC study." Obesity (Silver Spring). 2009;17(1):143-9.
Houston DK, Stevens J, Cai J. "Abdominal fat distribution and functional limitations and disability in a biracial cohort: the Atherosclerosis Risk in Communities Study." Int J Obes (Lond). 2005;29(12):1457-63.
Hoogeveen RC, Gaubatz JW, Sun W, et al. "Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study." Arterioscler Thromb Vasc Biol. 2014;34(5):1069-77.
Hoogeveen RC, Morrison A, Boerwinkle E, et al. "Plasma MCP-1 level and risk for peripheral arterial disease and incident coronary heart disease: Atherosclerosis Risk in Communities study." Atherosclerosis. 2005;183(2):301-7.
Hoogeveen RC, Ballantyne CM, Bang H, et al. "Circulating oxidised low-density lipoprotein and intercellular adhesion molecule-1 and risk of type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study." Diabetologia. 2007;50(1):36-42.
Hong J, Surapaneni A, Daya N, et al. "Retinopathy and Risk of Kidney Disease in Persons With Diabetes." Kidney Med. 2021;3(5):808-815.e1.
Hong J, Hatchell KE, Bradfield JP, et al. "Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations." J Clin Endocrinol Metab. 2018;103(4):1380-1392.
Hong YSoo, Longchamps RJ, Zhao D, et al. "Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2020;141(22):1823-1825.
Honda Y, Mok Y, Mathews L, et al. "Psychosocial factors and subsequent risk of hospitalizations with peripheral artery disease: The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2021;329:36-43.
Honda Y, Mok Y, Ishigami J, et al. "The Fifth-Generation Cardiac Troponin T and Cardiovascular Disease in the Community." J Am Coll Cardiol. 2021;78(20):2019-2021.
Holmes MV, Exeter HJ, Folkersen L, et al. "Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels." Circ Cardiovasc Genet. 2014;7(2):144-50.
Holmes MV, Dale CE, Zuccolo L, et al. "Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data." BMJ. 2014;349:g4164.
Holmes MV, Asselbergs FW, Palmer TM, et al. "Mendelian randomization of blood lipids for coronary heart disease." Eur Heart J. 2015;36(9):539-50.
Holmes MV, Lange LA, Palmer T, et al. "Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
Holliday EG, Traylor M, Malik R, et al. "Genetic overlap between diagnostic subtypes of ischemic stroke." Stroke. 2015;46(3):615-9.

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