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ARIC Publications

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Kahali B, Chen Y, Feitosa MF, et al. "A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
Kalbaugh CA, Kucharska-Newton AMaria, Wruck L, et al. "Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2017;6(5).
Kalbaugh CA, Loehr LR, Wruck L, et al. "Frequency of Care and Mortality Following an Incident Diagnosis of Peripheral Artery Disease in the Inpatient or Outpatient Setting: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
Kamel H, O'Neal WT, Okin PM, Loehr LR, Alonso A. "Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study." Ann Neurol. 2015;78(5):670-8.
Kan H, Heiss G, Rose KM, Whitsel E, Lurmann F, London SJ. "Traffic exposure and lung function in adults: the Atherosclerosis Risk in Communities study." Thorax. 2007;62(10):873-9.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Kan H, Folsom AR, Cushman M, et al. "Traffic exposure and incident venous thromboembolism in the Atherosclerosis Risk in Communities (ARIC) Study." J Thromb Haemost. 2011;9(4):672-8.
Kan H, Stevens J, Heiss G, Rose KM, London SJ. "Dietary fiber, lung function, and chronic obstructive pulmonary disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2008;167(5):570-8.
Kan H, Heiss G, Rose KM, Whitsel EA, Lurmann F, London SJ. "Prospective analysis of traffic exposure as a risk factor for incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study." Environ Health Perspect. 2008;116(11):1463-8.
Kang S, Cai J. "Marginal additive hazards model for case-cohort studies with multiple disease outcomes: an application to the Atherosclerosis Risk in Communities (ARIC) study." Biostatistics. 2013;14(1):28-41.
Kanoni S, Nettleton JA, Hivert M-F, et al. "Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis." Diabetes. 2011;60(9):2407-16.
Kantor DB, Palmer CD, Young TR, et al. "Replication and fine mapping of asthma-associated loci in individuals of African ancestry." Hum Genet. 2013;132(9):1039-47.
Kao LWH, Coresh J, Shuldiner AR, Boerwinkle E, Bray MS, Brancati FL. "Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 2003;52(6):1568-72.
Kao WH, Puddey IB, Boland LL, Watson RL, Brancati FL. "Alcohol consumption and the risk of type 2 diabetes mellitus: atherosclerosis risk in communities study." Am J Epidemiol. 2001;154(8):748-57.
Kao LWH, Arking DE, Post W, et al. "Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations." Circulation. 2009;119(7):940-51.
Kao WH, Folsom AR, Nieto FJ, Mo JP, Watson RL, Brancati FL. "Serum and dietary magnesium and the risk for type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study." Arch Intern Med. 1999;159(18):2151-9.
Kapoor A, Bakshy K, Xu L, et al. "Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
Kapoor A, Lee D, Zhu L, et al. "Multiple variant enhancers modulate its cardiac gene expression and the QT interval." Proc Natl Acad Sci U S A. 2019;116(22):10636-10645.
Kapoor A, Sekar RB, Hansen NF, et al. "An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval." Am J Hum Genet. 2014;94(6):854-69.
Kapur VK, Baldwin CM, Resnick HE, Gottlieb DJ, Nieto JF. "Sleepiness in patients with moderate to severe sleep-disordered breathing." Sleep. 2005;28(4):472-7.
Karaca E, Harel T, Pehlivan D, et al. "Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease." Neuron. 2015;88(3):499-513.
Kats D, Sharrett ARichey, Ginsberg HN, Nambi V, Ballantyne CM, Hoogeveen RC. "Postprandial lipemia and the risk of coronary heart disease and stroke: the Atherosclerosis Risk in Communities (ARIC) Study." BMJ Open Diabetes Res Care. 2017;5(1):e000335.
Kats D, Evenson KR, Zeng D, Avery CL, Palta P, Kritchevsky SB. "Leisure-time physical activity volume, intensity, and duration from mid- to late-life in U.S. subpopulations by race and sex. The Atherosclerosis Risk In Communities (ARIC) Study." Aging (Albany NY). 2020;12(5):4592-4602.
Kats D, Patel MD, Palta P, et al. "Social support and cognition in a community-based cohort: the Atherosclerosis Risk in Communities (ARIC) study." Age Ageing. 2016;45(4):475-80.
Katz EG, Stevens J, Truesdale KP, Cai J, North KE. "Associations of body mass index with incident hypertension in American white, American black and Chinese Asian adults in early and middle adulthood: the Coronary Artery Risk Development in Young Adults (CARDIA) study, the Atherosclerosis Risk in Communiti." Asia Pac J Clin Nutr. 2013;22(4):626-34.
Kaufman BG, Sueta CA, Chen C, B Windham G. "Are Trends in Hospitalization Prior to Hospice Use Associated With Hospice Episode Characteristics?" Am J Hosp Palliat Care. 2017;34(9):860-868.
Kawasaki R, Cheung N, Mosley T, et al. "Retinal microvascular signs and 10-year risk of cerebral atrophy: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2010;41(8):1826-8.
Keaton JM, Gao C, Guan M, et al. "Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans." Genet Epidemiol. 2018;42(6):559-570.
Keaton JM, Hellwege JN, C Y Ng M, et al. "Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans." PLoS One. 2016;11(7):e0159977.
Keene KL, Hyacinth HI, Bis JC, et al. "Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke." Stroke. 2020;51(8):2454-2463.
Keller MF, Reiner AP, Okada Y, et al. "Trans-ethnic meta-analysis of white blood cell phenotypes." Hum Mol Genet. 2014;23(25):6944-60.
Keogh RH, Seaman SR, Bartlett JW. "Multiple imputation of missing data in nested case-control and case-cohort studies." Biometrics. 2018;74(4):1438-1449.
Kessler MD, Loesch DP, Perry JA, et al. "De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population." Proc Natl Acad Sci U S A. 2020;117(5):2560-2569.
Khalid U, Wruck LMiller, Quibrera PMiguel, et al. "BNP and obesity in acute decompensated heart failure with preserved vs. reduced ejection fraction: The Atherosclerosis Risk in Communities Surveillance Study." Int J Cardiol. 2017;233:61-66.
Khalid U, Ather S, Bavishi C, et al. "Pre-morbid body mass index and mortality after incident heart failure: the ARIC Study." J Am Coll Cardiol. 2014;64(25):2743-9.
Khera AV, Emdin CA, Drake I, et al. "Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease." N Engl J Med. 2016;375(24):2349-2358.
Khera AV, Won H-H, Peloso GM, et al. "Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia." J Am Coll Cardiol. 2016;67(22):2578-89.
Kilarski LL, Achterberg S, Devan WJ, et al. "Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12." Neurology. 2014;83(8):678-85.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Coresh JJ. "Plant-Based Diets Are Associated With a Lower Risk of Incident Cardiovascular Disease, Cardiovascular Disease Mortality, and All-Cause Mortality in a General Population of Middle-Aged Adults." J Am Heart Assoc. 2019;8(16):e012865.
Kim SJoo, Reed N, Betz JF, et al. "Association Between Microvascular Retinal Signs and Age-Related Hearing Loss in the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." JAMA Otolaryngol Head Neck Surg. 2020;146(2):152-159.
Kim H, Hu EA, Wong KE, et al. "Serum Metabolites Associated with Healthy Diets in African Americans and European Americans." J Nutr. 2021;151(1):40-49.
Kim S, Cai J. "Improving the efficiency of estimation in the additive hazards model for stratified case-cohort design with multiple diseases." Stat Med. 2016;35(2):282-93.
Kim ED, Tanaka H, Ballew SH, Sang Y, Heiss G, Coresh JJ. "Associations Between Kidney Disease Measures and Regional Pulse Wave Velocity in a Large Community-Based Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(5):682-690.
Kim Y, Matsushita K, Sang Y, et al. "Association of high-sensitivity cardiac troponin T and natriuretic peptide with incident ESRD: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(4):550-8.
Kim SM, Zhao D, Schneider ALC, et al. "Association of parathyroid hormone with 20-year cognitive decline: The ARIC study." Neurology. 2017;89(9):918-926.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Grams ME, Coresh JJ. "Plant-Based Diets and Incident CKD and Kidney Function." Clin J Am Soc Nephrol. 2019;14(5):682-691.
Kim J, Wang W, Zhang M, et al. "Diurnal circadian variations in paroxysmal atrial fibrillation: The atherosclerosis risk in communities (ARIC) study." J Electrocardiol. 2020;63:98-103.
Kim H, Rebholz CM, Garcia-Larsen V, Steffen LM, Coresh JJ. "Operational Differences in Plant-Based Diet Indices Affect the Ability to Detect Associations with Incident Hypertension in Middle-Aged US Adults." J Nutr. 2020;150(4):842-850.
Kim ED, Ballew SH, Tanaka H, Heiss G, Coresh JJ. "Short-Term Prognostic Impact of Arterial Stiffness in Older Adults Without Prevalent Cardiovascular Disease." Hypertension. 2019;74(6):1373-1382.
Kim ED, Soliman EZ, Coresh J, Matsushita K, Chen LYee. "Two-Week Burden of Arrhythmias across CKD Severity in a Large Community-Based Cohort: The ARIC Study." J Am Soc Nephrol. 2021;32(3):629-638.
Kingah PL, Luu HN, Volcik KA, Morrison AC, Nettleton JA, Boerwinkle E. "Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study." Hypertens Res. 2010;33(2):165-9.
Kitzmiller JP, Foraker RE. "Lipid-lowering pharmacotherapy and socioeconomic status: Atherosclerosis Risk In Communities (ARIC) surveillance study." BMC Public Health. 2013;13:488.
Klein R, A Sharrett R, Klein BEK, et al. "The association of atherosclerosis, vascular risk factors, and retinopathy in adults with diabetes : the atherosclerosis risk in communities study." Ophthalmology. 2002;109(7):1225-34.
Klein R, Sharrett AR, Klein BE, et al. "Are retinal arteriolar abnormalities related to atherosclerosis?: The Atherosclerosis Risk in Communities Study." Arterioscler Thromb Vasc Biol. 2000;20(6):1644-50.
Klein R, Clegg L, Cooper LS, et al. "Prevalence of age-related maculopathy in the Atherosclerosis Risk in Communities Study." Arch Ophthalmol. 1999;117(9):1203-10.
Klimentidis YC, Arora A, Zhou J, Kittles R. "The Genetic Contribution of West-African Ancestry to Protection against Central Obesity in African-American Men but Not Women: Results from the ARIC and MESA Studies." Front Genet. 2016;7:89.
Klimentidis YC, Raichlen DA, Bea J, et al. "Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE." Int J Obes (Lond). 2018;42(6):1161-1176.
Klos K, Shimmin L, Ballantyne C, et al. "APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels." Hum Mol Genet. 2008;17(13):2039-46.
Knol MJ, Lu D, Traylor M, et al. "Association of common genetic variants with brain microbleeds: A genome-wide association study." Neurology. 2020;95(24):e3331-e3343.
Knopman DS, Penman AD, Catellier DJ, et al. "Vascular risk factors and longitudinal changes on brain MRI: the ARIC study." Neurology. 2011;76(22):1879-85.
Knopman DS, Griswold ME, Lirette ST, et al. "Vascular imaging abnormalities and cognition: mediation by cortical volume in nondemented individuals: atherosclerosis risk in communities-neurocognitive study." Stroke. 2015;46(2):433-40.
Knopman DS, Gottesman RF, Sharrett ARichey, et al. "Mild Cognitive Impairment and Dementia Prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." Alzheimers Dement (Amst). 2016;2:1-11.
Knopman DS, Mosley TH, Catellier DJ, A Sharrett R. "Cardiovascular risk factors and cerebral atrophy in a middle-aged cohort." Neurology. 2005;65(6):876-81.
Knopman DS, Gottesman RF, Sharrett ARichey, et al. "Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2018;14(11):1406-1415.
Knopman DS, Mosley TH, Catellier DJ, Coker LH. "Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study." Alzheimers Dement. 2009;5(3):207-14.
Knopman D, Boland LL, Mosley T, et al. "Cardiovascular risk factors and cognitive decline in middle-aged adults." Neurology. 2001;56(1):42-8.
Knowles JW, Assimes TL, Boerwinkle E, et al. "Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD." BMC Med Genet. 2008;9:23.
Knuiman MW, Folsom AR, Chambless LE, Liao D, Wu KK. "Association of hemostatic variables with MRI-detected cerebral abnormalities: the atherosclerosis risk in communities study." Neuroepidemiology. 2001;20(2):96-104.
Kocarnik JM, Pendergrass SA, Carty CL, et al. "Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study." Circ Cardiovasc Genet. 2014;7(2):178-88.
Kocarnik JM, Richard M, Graff M, et al. "Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study." Hum Mol Genet. 2018;27(16):2940-2953.
Koene RJ, M Alraies C, Norby FL, et al. "Relation of the CHADS-VASc Score to Risk of Thrombotic and Embolic Stroke in Community-Dwelling Individuals Without Atrial Fibrillation (From The Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2019;123(3):402-408.
Kohsaka S, Volcik KA, Folsom AR, et al. "Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study." Atherosclerosis. 2008;196(2):926-30.
Konety S, Koene RJ, Norby FL, et al. "Echocardiographic Predictors of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study and Cardiovascular Health Study." Circ Cardiovasc Imaging. 2016;9(8).
Kong L, Cai J. "Case-cohort analysis with accelerated failure time model." Biometrics. 2009;65(1):135-42.
Korada SKrishna C, Zhao D, Gottesman RF, et al. "Parathyroid Hormone and Subclinical Cerebrovascular Disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study." J Stroke Cerebrovasc Dis. 2016;25(4):883-93.
Kors JA, Crow RS, Hannan PJ, Rautaharju PM, Folsom AR. "Comparison of computer-assigned Minnesota Codes with the visual standard method for new coronary heart disease events." Am J Epidemiol. 2000;151(8):790-7.
Koton S, Schneider ALC, B Windham G, Mosley TH, Gottesman RF. "Microvascular Brain Disease Progression and Risk of Stroke: The ARIC Study." Stroke. 2020;51(11):3264-3270.
Koton S, Schneider ALC, Rosamond WD, Shahar E, Sang Y, Gottesman RF. "Stroke incidence and mortality trends in US communities, 1987 to 2011." JAMA. 2014;312(3):259-68.