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ARIC Publications

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Raffield LM, Iyengar AK, Wang B, et al. "Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts." Am J Hum Genet. 2020;106(1):112-120.
Raina A, Zhao X, Grove ML, et al. "Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study." Clin Epigenetics. 2017;9:21.
Ramalho SHR, Santos M, Claggett B, et al. "Association of Undifferentiated Dyspnea in Late Life With Cardiovascular and Noncardiovascular Dysfunction: A Cross-sectional Analysis From the ARIC Study." JAMA Netw Open. 2019;2(6):e195321.
Ranjit N, Diez-Roux AV, Chambless L, Jacobs DR, Nieto JF, Szklo M. "Socioeconomic differences in progression of carotid intima-media thickness in the Atherosclerosis Risk in Communities study." Arterioscler Thromb Vasc Biol. 2006;26(2):411-6.
Rannikmae K, Sivakumaran V, Millar H, et al. " is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls." Neurology. 2017;89(17):1829-1839.
Rapsomaniki E, White IR, Wood AM. "A framework for quantifying net benefits of alternative prognostic models." Stat Med. 2012;31(2):114-30.
Rapson IR, Michos ED, Alonso A, Hirsch AT, Matsushita K, Reis JP. "Serum 25-hydroxyvitamin D is associated with incident peripheral artery disease among white and black adults in the ARIC study cohort." Atherosclerosis. 2017;257:123-129.
Rasmussen ML, Folsom AR, Catellier DJ, Tsai MY, Garg U, Eckfeldt JH. "A prospective study of coronary heart disease and the hemochromatosis gene (HFE) C282Y mutation: the Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2001;154(3):739-46.
Rasmussen-Torvik LJ, Alonso A, Li M, et al. "Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose." Genet Epidemiol. 2010;34(7):665-73.
Rasmussen-Torvik LJ, Shay CM, Abramson JG, Friedrich CA, Nettleton JA, Prizment AE. "Ideal cardiovascular health is inversely associated with incident cancer: the Atherosclerosis Risk In Communities study." Circulation. 2013;127(12):1270-5.
Rasmussen-Torvik LJ, Li M, Kao WH, et al. "Association of a fasting glucose genetic risk score with subclinical atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study." Diabetes. 2011;60(1):331-5.
Rasmussen-Torvik LJ, Cushman M, Tsai MY, et al. "The association of alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study." Thromb Res. 2007;121(1):1-7.
Rasmussen-Torvik LJ, Yatsuya H, Selvin E, Alonso A, Folsom AR. "Demographic and cardiovascular risk factors modify association of fasting insulin with incident coronary heart disease and ischemic stroke (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2010;105(10):1420-5.
Råstam L, Lindberg G, Folsom AR, Burke GL, Nilsson-Ehle P, Lundblad A. "Association between serum sialic acid concentration and carotid atherosclerosis measured by B-mode ultrasound. The ARIC Investigators. Atherosclerosis Risk in Communities Study." Int J Epidemiol. 1996;25(5):953-8.
Rathore SS, Hinn AR, Cooper LS, Tyroler HA, Rosamond WD. "Characterization of incident stroke signs and symptoms: findings from the atherosclerosis risk in communities study." Stroke. 2002;33(11):2718-21.
Rattani A, Claxton J'NS, Ali MK, Chen LYee, Soliman EZ. "Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in The Atherosclerosis Risk in Communities study." BMC Cardiovasc Disord. 2019;19(1):262.
Rautaharju PM, Park L, Rautaharju FS, Crow R. "A standardized procedure for locating and documenting ECG chest electrode positions: consideration of the effect of breast tissue on ECG amplitudes in women." J Electrocardiol. 1998;31(1):17-29.
Rautaharju PM, Prineas RJ, Wood J, Zhang Z-M, Crow R, Heiss G. "Electrocardiographic predictors of new-onset heart failure in men and in women free of coronary heart disease (from the Atherosclerosis in Communities [ARIC] Study)." Am J Cardiol. 2007;100(9):1437-41.
Rautaharju PM, Zhang Z-M, Haisty WK, Kucharska-Newton AMaria, Rosamond WD. "Electrocardiographic repolarization-related predictors of coronary heart disease and sudden cardiac deaths in men and women with cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study." J Electrocardiol. 2015;48(1):101-11.
Rautaharju PM, Zhang Z-M, Haisty WK, Prineas RJ, Kucharska-Newton AMaria, Rosamond WD. "Electrocardiographic predictors of incident heart failure in men and women free from manifest cardiovascular disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2013;112(6):843-9.
Rautaharju PM, Zhang Z-M, Haisty WK, et al. "Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2014;47(3):342-50.
Rautaharju PM, Zhang Z-M, Warren J, et al. "Electrocardiographic predictors of coronary heart disease and sudden cardiac deaths in men and women free from cardiovascular disease in the Atherosclerosis Risk in Communities study." J Am Heart Assoc. 2013;2(3):e000061.
Rautaharju PM, Prineas RJ, Zhang Z-M. "A simple procedure for estimation of the spatial QRS/T angle from the standard 12-lead electrocardiogram." J Electrocardiol. 2007;40(3):300-4.
Rawlings AM, Sharrett ARichey, Golden SH, Windham BG. "Prevalence and correlates of depressive symptoms in older adults across the glycaemic spectrum: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2018;35(5):583-587.
Rawlings AM, Juraschek SP, Heiss G, et al. "Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline." Neurology. 2018;91(8):e759-e768.
Rawlings AM, Sharrett ARichey, Mosley TH, Wong DF, Knopman DS. "Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life." J Alzheimers Dis. 2019;68(2):517-521.
Rawlings AM, Bandeen-Roche K, Gross AL, et al. "Factor structure of the ARIC-NCS Neuropsychological Battery: An evaluation of invariance across vascular factors and demographic characteristics." Psychol Assess. 2016;28(12):1674-1683.
Rawlings AMonica, Sang Y, Sharrett ARichey, et al. "Multiple imputation of cognitive performance as a repeatedly measured outcome." Eur J Epidemiol. 2017;32(1):55-66.
Rawlings AM, Sharrett ARichey, Mosley TH, Ballew SH, Deal JA. "Glucose Peaks and the Risk of Dementia and 20-Year Cognitive Decline." Diabetes Care. 2017;40(7):879-886.
Rawlings AM, Sharrett ARichey, Schneider ALC, et al. "Diabetes in midlife and cognitive change over 20 years: a cohort study." Ann Intern Med. 2014;161(11):785-93.
Rawlings AM, Sharrett ARichey, Albert MS, et al. "The Association of Late-Life Diabetes Status and Hyperglycemia With Incident Mild Cognitive Impairment and Dementia: The ARIC Study." Diabetes Care. 2019;42(7):1248-1254.
Ray D, Pankow JS. "USAT: A Unified Score-Based Association Test for Multiple Phenotype-Genotype Analysis." Genet Epidemiol. 2016;40(1):20-34.
Ray D, Li X, Pan W, Pankow JS. "A Bayesian Partitioning Model for the Detection of Multilocus Effects in Case-Control Studies." Hum Hered. 2015;79(2):69-79.
Raynor LA, Pankow JS, Rasmussen-Torvik LJ, Tang W, Prizment A. "Pleiotropy and pathway analyses of genetic variants associated with both type 2 diabetes and prostate cancer." Int J Mol Epidemiol Genet. 2013;4(1):49-60.
Raynor LA, Pankow JS, Duncan BB, et al. "Novel risk factors and the prediction of type 2 diabetes in the Atherosclerosis Risk in Communities (ARIC) study." Diabetes Care. 2013;36(1):70-6.
Rebholz CM, Grams ME, Coresh JJ, et al. "Serum fibroblast growth factor-23 is associated with incident kidney disease." J Am Soc Nephrol. 2015;26(1):192-200.
Rebholz CM, Anderson CAM, Grams ME, et al. "Relationship of the American Heart Association's Impact Goals (Life's Simple 7) With Risk of Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Cohort Study." J Am Heart Assoc. 2016;5(4):e003192.
Rebholz CM, Grams ME, Steffen LM, et al. "Diet Soda Consumption and Risk of Incident End Stage Renal Disease." Clin J Am Soc Nephrol. 2017;12(1):79-86.
Rebholz CM, Grams ME, Chen Y, Gross AL, Sang Y, Coresh JJ. "Serum Levels of 1,5-Anhydroglucitol and Risk of Incident End-Stage Renal Disease." Am J Epidemiol. 2017;186(8):952-960.
Rebholz CM, Grams ME, Lutsey PL, et al. "Biomarkers of Vitamin D Status and Risk of ESRD." Am J Kidney Dis. 2016;67(2):235-42.
Rebholz CM, Grams ME, Matsushita K, et al. "Change in Multiple Filtration Markers and Subsequent Risk of Cardiovascular Disease and Mortality." Clin J Am Soc Nephrol. 2015;10(6):941-8.
Rebholz CM, Yu B, Zheng Z, et al. "Serum metabolomic profile of incident diabetes." Diabetologia. 2018;61(5):1046-1054.
Rebholz CM, Coresh JJ, Ballew SH, McMahon B, Whelton SP, Selvin E. "Kidney Failure and ESRD in the Atherosclerosis Risk in Communities (ARIC) Study: Comparing Ascertainment of Treated and Untreated Kidney Failure in a Cohort Study." Am J Kidney Dis. 2015;66(2):231-9.
Rebholz CM, Coresh JJ, Grams ME, Steffen LM, Anderson CAM, Appel LJ. "Dietary Acid Load and Incident Chronic Kidney Disease: Results from the ARIC Study." Am J Nephrol. 2015;42(6):427-35.
Rebholz CM, Crews DC, Grams ME, et al. "DASH (Dietary Approaches to Stop Hypertension) Diet and Risk of Subsequent Kidney Disease." Am J Kidney Dis. 2016;68(6):853-861.
Rebholz CM, Astor BC, Grams ME, et al. "Association of plasma levels of soluble receptor for advanced glycation end products and risk of kidney disease: the Atherosclerosis Risk in Communities study." Nephrol Dial Transplant. 2015;30(1):77-83.
Rebholz CM, Selvin E, Liang M, et al. "Plasma galectin-3 levels are associated with the risk of incident chronic kidney disease." Kidney Int. 2018;93(1):252-259.
Rebholz CM, Grams ME, Matsushita K, Selvin E. "Change in novel filtration markers and risk of ESRD." Am J Kidney Dis. 2015;66(1):47-54.
Redline S, Min NI, Shahar E, Rapoport D, O'Connor G. "Polysomnographic predictors of blood pressure and hypertension: is one index best?" Sleep. 2005;28(9):1122-30.
Reed NS, Betz JF, Kucharska-Newton AMaria, Lin FR. "Hearing loss and satisfaction with healthcare: An unexplored relationship." J Am Geriatr Soc. 2019;67(3):624-626.
Reed NS, Huddle MG, Betz J, et al. "Association of Midlife Hypertension with Late-Life Hearing Loss." Otolaryngol Head Neck Surg. 2019;161(6):996-1003.
Reich LM, Folsom AR, Key NS, et al. "Prospective study of subclinical atherosclerosis as a risk factor for venous thromboembolism." J Thromb Haemost. 2006;4(9):1909-13.
Reich D, Nalls MA, Kao LWH, et al. "Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene." PLoS Genet. 2009;5(1):e1000360.
Reich LM, Heiss G, Boland LL, Hirsch AT, Wu K, Folsom AR. "Ankle-brachial index and hemostatic markers in the Atherosclerosis Risk in Communities (ARIC) study cohort." Vasc Med. 2007;12(4):267-73.
Reiner AP, Lettre G, Nalls MA, et al. "Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT)." PLoS Genet. 2011;7(6):e1002108.
Reis JP, Selvin E, Pankow JS, Michos ED, Rebholz CM. "Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
Reis JP, Michos ED, Selvin E, Pankow JS. "Race, vitamin D-binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2015;101(6):1232-40.
Resnick HE, Redline S, Shahar E, et al. "Diabetes and sleep disturbances: findings from the Sleep Heart Health Study." Diabetes Care. 2003;26(3):702-9.
Rhee EP, Yang Q, Yu B, et al. "An exome array study of the plasma metabolome." Nat Commun. 2016;7:12360.
Rhodin K, Divaris K, North KE, Barros SP, Moss K, Beck JD. "Chronic periodontitis genome-wide association studies: gene-centric and gene set enrichment analyses." J Dent Res. 2014;93(9):882-90.
Richard MA, Huan T, Ligthart S, et al. "DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation." Am J Hum Genet. 2017;101(6):888-902.
Richardson K, Nettleton JA, Rotllan N, et al. "Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site." Am J Hum Genet. 2013;92(1):5-14.
Ried JS, M JJeff, Chu AY, et al. "A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape." Nat Commun. 2016;7:13357.
Rifai MAl, Schneider ALC, Alonso A, et al. "sRAGE, inflammation, and risk of atrial fibrillation: results from the Atherosclerosis Risk in Communities (ARIC) Study." J Diabetes Complications. 2015;29(2):180-5.
Riley WA, Barnes RW, Evans GW, Burke GL. "Ultrasonic measurement of the elastic modulus of the common carotid artery. The Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 1992;23(7):952-6.
Riley WA, Evans GW, Sharrett AR, Burke GL, Barnes RW. "Variation of common carotid artery elasticity with intimal-medial thickness: the ARIC Study. Atherosclerosis Risk in Communities." Ultrasound Med Biol. 1997;23(2):157-64.
Roberts JD, Soliman EZ, Alonso A, Vittinghoff E, Chen LYee, Loehr LR. "Electrocardiographic intervals associated with incident atrial fibrillation: Dissecting the QT interval." Heart Rhythm. 2017;14(5):654-660.
Roberts JD, Hu D, Heckbert SR, et al. "Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals." JAMA Cardiol. 2016;1(4):442-50.
Roberts CB, Couper DJ, Chang PP, James SA, Rosamond WD, Heiss G. "Influence of life-course socioeconomic position on incident heart failure in blacks and whites: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2010;172(6):717-27.
Roberts JD, Dewland TA, Glidden DV, et al. "Impact of genetic variants on the upstream efficacy of renin-angiotensin system inhibitors for the prevention of atrial fibrillation." Am Heart J. 2016;175:9-17.
Robinson JC, Folsom AR, Nabulsi AA, Watson R, Brancati FL, Cai J. "Can postmenopausal hormone replacement improve plasma lipids in women with diabetes? The Atherosclerosis Risk in Communities Study Investigators." Diabetes Care. 1996;19(5):480-5.
Robinson JG, Boland LL, McGovern PG, Folsom AR. "A Comparison of NCEP and Absolute Risk Stratification Methods for Lipid-Lowering Therapy in Middle-Aged Adults: The ARIC Study. The ARIC Investigators." Prev Cardiol. 2001;4(4):148-157.
Robinson-Cohen C, Bartz TM, Lai D, et al. "Genetic Variants Associated with Circulating Fibroblast Growth Factor 23." J Am Soc Nephrol. 2018;29(10):2583-2592.
Robinson-Cohen C, Lutsey PL, Kleber ME, et al. "Genetic Variants Associated with Circulating Parathyroid Hormone." J Am Soc Nephrol. 2017;28(5):1553-1565.
Roca GQuerejeta, Redline S, Punjabi N, Claggett B, Ballantyne CM, Solomon SD. "Sleep apnea is associated with subclinical myocardial injury in the community. The ARIC-SHHS study." Am J Respir Crit Care Med. 2013;188(12):1460-5.
Roca GQuerejeta, Redline S, Claggett B, Bello N, Ballantyne CM, Solomon SD. "Sex-Specific Association of Sleep Apnea Severity With Subclinical Myocardial Injury, Ventricular Hypertrophy, and Heart Failure Risk in a Community-Dwelling Cohort: The Atherosclerosis Risk in Communities-Sleep Heart Health Study." Circulation. 2015;132(14):1329-37.
Rodgers JE, Thudium EM, Beyhaghi H, et al. "Predictors of Medication Adherence in the Elderly: The Role of Mental Health." Med Care Res Rev. 2018;75(6):746-761.
Rodin AS, Litvinenko A, Klos K, et al. "Use of wrapper algorithms coupled with a random forests classifier for variable selection in large-scale genomic association studies." J Comput Biol. 2009;16(12):1705-18.
Rodriguez S, Gaunt TR, Guo Y, et al. "Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array." Eur J Hum Genet. 2016;24(1):106-12.
Rodriguez CJ, Swett K, Agarwal SK, et al. "Systolic blood pressure levels among adults with hypertension and incident cardiovascular events: the atherosclerosis risk in communities study." JAMA Intern Med. 2014;174(8):1252-61.