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ARIC Publications

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Turcot V, Lu Y, Highland HM, et al. "Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity." Nat Genet. 2019;51(7):1191-1192.
Turcot V, Lu Y, Highland HM, et al. "Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity." Nat Genet. 2018;50(1):26-41.
Tsai AW, Cushman M, Tsai MY, et al. "Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2003;72(3):192-200.
Tsai AW, Cushman M, Rosamond WD, et al. "Coagulation factors, inflammation markers, and venous thromboembolism: the longitudinal investigation of thromboembolism etiology (LITE)." Am J Med. 2002;113(8):636-42.
Tsai AW, Cushman M, Rosamond WD, Heckbert SR, Polak JF, Folsom AR. "Cardiovascular risk factors and venous thromboembolism incidence: the longitudinal investigation of thromboembolism etiology." Arch Intern Med. 2002;162(10):1182-9.
Tsai AW, Folsom AR, Rosamond WD, Jones DW. "Ankle-brachial index and 7-year ischemic stroke incidence: the ARIC study." Stroke. 2001;32(8):1721-4.
Truesdale KP, Stevens J, Cai J. "The effect of weight history on glucose and lipids: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2005;161(12):1133-43.
Truesdale KP, Stevens J, Cai J. "Nine-year changes in cardiovascular disease risk factors with weight maintenance in the atherosclerosis risk in communities cohort." Am J Epidemiol. 2007;165(8):890-900.
Truesdale KP, Stevens J, Cai J. "Effect of 3-year weight history on blood pressure: the atherosclerosis risk in communities study." Obesity (Silver Spring). 2008;16(5):1112-9.
Traylor M, Malik R, Nalls MA, et al. "Genetic variation at 16q24.2 is associated with small vessel stroke." Ann Neurol. 2017;81(3):383-394.
Traylor M, Farrall M, Holliday EG, et al. "Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies." Lancet Neurol. 2012;11(11):951-62.
Travis RC, Perez-Cornago A, Appleby PN, et al. "A Collaborative Analysis of Individual Participant Data from 19 Prospective Studies Assesses Circulating Vitamin D and Prostate Cancer Risk." Cancer Res. 2019;79(1):274-285.
Tragante V, Barnes MR, Ganesh SK, et al. "Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci." Am J Hum Genet. 2014;94(3):349-60.
Toole JF, Lefkowitz DS, Chambless LE, Wijnberg L, Paton CC, Heiss G. "Self-reported transient ischemic attack and stroke symptoms: methods and baseline prevalence. The ARIC Study, 1987-1989." Am J Epidemiol. 1996;144(9):849-56.
Toole JF, Chambless LE, Heiss G, Tyroler HA, Paton CC. "Prevalence of stroke and transient ischemic attacks in the Atherosclerosis Risk in Communities (ARIC) study." Ann Epidemiol. 1993;3(5):500-3.
Ting J, Jiang K, Du S, et al. "Longitudinal Blood Pressure Patterns from Mid-to-Late Life and Late-life Hearing Loss in the Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2021.
Tin A, Grams ME, Ashar FN, et al. "Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study." J Am Soc Nephrol. 2016;27(8):2467-73.
Tin A, Colantuoni E, Boerwinkle E, et al. "Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate." J Hum Genet. 2013;58(7):461-6.
Tin A, Köttgen A, Folsom AR, et al. "Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study." BMC Genet. 2015;16:56.
Tin A, Grams ME, Maruthur NM, et al. "Results from the Atherosclerosis Risk in Communities study suggest that low serum magnesium is associated with incident kidney disease." Kidney Int. 2015;87(4):820-7.
Tin A, Yu B, Ma J, et al. "Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay." J Appl Lab Med. 2019;4(1):30-39.
Tin A, Astor BC, Boerwinkle E, Hoogeveen RC, Coresh JJ. "Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin." Hum Genet. 2013;132(6):619-27.
Tin A, Grams ME, Maruthur NM, et al. "Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(5):784-90.
Tin A, Astor BC, Boerwinkle E, Hoogeveen RC, Coresh JJ. "Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans." Nephrol Dial Transplant. 2013;28(6):1497-504.
Tin A, Balakrishnan P, Beaty TH, Boerwinkle E, Hoogeveen RC, Young JH. "GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2016;33(7):968-75.
Tin A, Walker KA, Bressler J, et al. "Association between Circulating Protein C Levels and Incident Dementia: The Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2021;55(4):306-315.
Tin A, Woodward OM, Kao W H L, et al. "Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele." Hum Mol Genet. 2011;20(20):4056-68.
Tin A, Scharpf R, Estrella MM, et al. "The Loss of Associates with Kidney Failure and Heart Failure." J Am Soc Nephrol. 2017;28(11):3345-3352.
Tin A, Li Y, Brody JA, et al. "Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels." Nat Commun. 2018;9(1):4228.
Tin A, Marten J, Kuhns VLHalperin, et al. "Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels." Nat Genet. 2019;51(10):1459-1474.
Tilling K, Smith G D, Chambless L, et al. "The relation between birth weight and intima-media thickness in middle-aged adults." Epidemiology. 2004;15(5):557-64.
Tilling K, Sterne JAC, Szklo M. "Estimating the effect of cardiovascular risk factors on all-cause mortality and incidence of coronary heart disease using G-estimation: the atherosclerosis risk in communities study." Am J Epidemiol. 2002;155(8):710-8.
Tilling K, Lawlor DA, Smith GDavey, Chambless L, Szklo M. "The relation between components of adult height and intimal-medial thickness in middle age: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2006;164(2):136-42.
Tikellis G, Arnett DK, Skelton TN, et al. "Retinal arteriolar narrowing and left ventricular hypertrophy in African Americans. the Atherosclerosis Risk in Communities (ARIC) study." Am J Hypertens. 2008;21(3):352-9.
Tikellis G, Anuradha S, Klein R, Wong T Y. "Association between physical activity and retinal microvascular signs: the Atherosclerosis Risk in Communities (ARIC) Study." Microcirculation. 2010;17(5):381-93.
Thyagarajan B, Brott M, Mink P, et al. "CYP1B1 and CYP19 gene polymorphisms and breast cancer incidence: no association in the ARIC study." Cancer Lett. 2004;207(2):183-9.
Thorvaldsen T, Claggett BL, Shah A, et al. "Predicting Risk in Patients Hospitalized for Acute Decompensated Heart Failure and Preserved Ejection Fraction: The Atherosclerosis Risk in Communities Study Heart Failure Community Surveillance." Circ Heart Fail. 2017;10(12).
Thorgeirsson TE, Gudbjartsson DF, Sulem P, et al. "A common biological basis of obesity and nicotine addiction." Transl Psychiatry. 2013;3:e308.
Crosby J, Peloso GM, Auer PL, et al. "Loss-of-function mutations in APOC3, triglycerides, and coronary disease." N Engl J Med. 2014;371(1):22-31.
Teumer A, Li Y, Ghasemi S, et al. "Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria." Nat Commun. 2019;10(1):4130.
Teumer A, Tin A, Sorice R, et al. "Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes." Diabetes. 2016;65(3):803-17.
Teumer A, Chaker L, Groeneweg S, et al. "Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.
Teslovich TM, Musunuru K, Smith AV, et al. "Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
Terry JG, Hinson WH, Evans GW, Schreiner PJ, Hagaman AP, Crouse JR. "Evaluation of magnetic resonance imaging for quantification of intraabdominal fat in human beings by spin-echo and inversion-recovery protocols." Am J Clin Nutr. 1995;62(2):297-301.
Tereshchenko LG, Henrikson CA, Sotoodehnia N, et al. "Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study." J Am Heart Assoc. 2014;3(6):e001387.
Tereshchenko LG, Sotoodehnia N, Sitlani CM, et al. "Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)." J Am Heart Assoc. 2018;7(8).
Teramoto K, Junior WNadruz, Matsushita K, et al. "Mid- to Late-Life Time-Averaged Cumulative Blood Pressure and Late-Life Cardiac Structure, Function, and Heart Failure." Hypertension. 2020;76(3):808-818.
Tennessen JA, Bigham AW, O'Connor TD, et al. "Evolution and functional impact of rare coding variation from deep sequencing of human exomes." Science. 2012;337(6090):64-9.
Haycock PC, Burgess S, Nounu A, et al. "Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study." JAMA Oncol. 2017;3(5):636-651.
Tell GS, Evans GW, Folsom AR, Shimakawa T, Carpenter MA, Heiss G. "Dietary fat intake and carotid artery wall thickness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1994;139(10):979-89.
Taylor KC, Carty CL, Dumitrescu L, et al. "Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study." BMC Genet. 2013;14:33.
Taylor HA, Penman AD, Han H, et al. "Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2007;99(10):1413-20.
Taylor HA, Clark BL, Garrison RJ, et al. "Relation of aortic valve sclerosis to risk of coronary heart disease in African-Americans." Am J Cardiol. 2005;95(3):401-4.
Tariq A, Chen J, Yu B, et al. "Metabolomics of Dietary Acid Load and Incident Chronic Kidney Disease." J Ren Nutr. 2021.
Tao R, Zeng D, Franceschini N, North KE, Boerwinkle E. "Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling." J Am Stat Assoc. 2015;110(510):560-572.
Tangri N, Grams ME, Levey AS, et al. "Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis." JAMA. 2016;315(2):164-74.
Tang W, Schwienbacher C, Lopez LM, et al. "Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease." Am J Hum Genet. 2012;91(1):152-62.
Tang W, Stimson MRachel, Basu S, et al. "Burden of rare exome sequence variants in PROC gene is associated with venous thromboembolism: a population-based study." J Thromb Haemost. 2020;18(2):445-453.
Tang W, Morrison A, Wasserman BA, et al. "Association of SERPINA9 gene variants with carotid artery atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study." Int J Mol Epidemiol Genet. 2013;4(4):258-67.
Tang O, Matsushita K, Coresh JJ, et al. "High-Sensitivity Cardiac Troponin I for Risk Stratification in Older Adults." J Am Geriatr Soc. 2020.
Tang W, Yao L, Roetker NS, et al. "Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
Tang W, Saratzis A, Pattee J, et al. "Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG." Eur J Vasc Endovasc Surg. 2020;59(1):92-97.
Tang O, Matsushita K, Coresh JJ, et al. "High-Sensitivity Cardiac Troponin I and T for Cardiovascular Risk Stratification in Adults With Diabetes." Diabetes Care. 2020;43(10):e144-e146.
Tang W, Yao L, Hoogeveen RC, et al. "The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study." Angiology. 2019;70(2):130-140.
Tang W, Kowgier M, Loth DW, et al. "Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function." PLoS One. 2014;9(7):e100776.
Tang O, Daya N, Matsushita K, et al. "Performance of High-Sensitivity Cardiac Troponin Assays to Reflect Comorbidity Burden and Improve Mortality Risk Stratification in Older Adults With Diabetes." Diabetes Care. 2020;43(6):1200-1208.
Tang W, Teichert M, Chasman DI, et al. "A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium." Genet Epidemiol. 2013;37(5):512-521.
Tang W, Cushman M, Green D, et al. "Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans." Am J Hematol. 2015;90(6):534-40.
Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Tang W, Basu S, Kong X, et al. "Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study." Blood. 2010;116(23):5032-6.
Tandon A, Chen CJ, Penman A, et al. "African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans." Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005.
Tande AJ, Platz EA, Folsom AR. "The metabolic syndrome is associated with reduced risk of prostate cancer." Am J Epidemiol. 2006;164(11):1094-102.
Tanaka H, Heiss G, McCabe EL, et al. "Hemodynamic Correlates of Blood Pressure in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." J Clin Hypertens (Greenwich). 2016;18(12):1222-1227.
Tanaka H, Palta P, Folsom AR, et al. "Habitual physical activity and central artery stiffening in older adults: the Atherosclerosis Risk in Communities study." J Hypertens. 2018;36(9):1889-1894.
Tamariz L, Agarwal S, Soliman EZ, et al. "Association of serum uric acid with incident atrial fibrillation (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2011;108(9):1272-6.
Tamariz LJ, Young HJ, Pankow JS, et al. "Blood viscosity and hematocrit as risk factors for type 2 diabetes mellitus: the atherosclerosis risk in communities (ARIC) study." Am J Epidemiol. 2008;168(10):1153-60.
Takiar R, Lutsey PL, Zhao D, et al. "The associations of 25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms, and race with risk of incident fracture-related hospitalization: Twenty-year follow-up in a bi-ethnic cohort (the ARIC Study)." Bone. 2015;78:94-101.
Tajuddin SM, Schick UM, Eicher JD, et al. "Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases." Am J Hum Genet. 2016;99(1):22-39.
Tabor HK, Auer PL, Jamal SM, et al. "Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.