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ARIC Publications

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Wyss AB, Sofer T, Lee MKyeong, et al. "Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function." Nat Commun. 2018;9(1):2976.
Wuttke M, Li Y, Li M, et al. "A catalog of genetic loci associated with kidney function from analyses of a million individuals." Nat Genet. 2019;51(6):957-972.
Wu KK, Papp AC, Patsch W, Rock R, Eckfeldt J, Sharrett R. "ARIC hemostasis study--II. Organizational plan and feasibility study." Thromb Haemost. 1990;64(4):521-5.
Wu B. "Statistical methods for association tests of multiple continuous traits in genome-wide association studies." Ann Hum Genet. 2015;79(4):282-93.
Wu B. "Genome-wide association test of multiple continuous traits using imputed SNPs." Stat Interface. 2017;10(3):379-386.
Wu B. "Sequence Kernel Association Test of Multiple Continuous Phenotypes." Genet Epidemiol. 2016;40(2):91-100.
Wu KK, Folsom AR, Heiss G, Davis CE, Conlan MG, Barnes R. "Association of coagulation factors and inhibitors with carotid artery atherosclerosis. Early results of the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 1992;2(4):471-80.
Wu B, Guan W. "On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set." Ann Hum Genet. 2016;80(2):123-35.
Wu KK, Aleksic N, Ballantyne CM, Ahn C, Juneja H, Boerwinkle E. "Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease." Circulation. 2003;107(13):1729-32.
Wu A, Sharrett ARichey, Gottesman RF, et al. "Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment." JAMA Netw Open. 2019;2(5):e193359.
Wu B, Pankow JS. "Sequence Kernel Association Analysis of Rare Variant Set Based on the Marginal Regression Model for Binary Traits." Genet Epidemiol. 2015;39(6):399-405.
Wu C, Zhang K, Odden MC, et al. "Subclinical Vascular Disease Burden and Premature Mortality Among Middle-aged Adults: the Atherosclerosis Risk in Communities Study." J Gen Intern Med. 2021.
Wu B. "Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits." Comput Math Methods Med. 2018;2018:2564531.
Wu Y, Waite LL, Jackson AU, et al. "Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained." PLoS Genet. 2013;9(3):e1003379.
Wu KK, Aleksic N, Ahn C, Boerwinkle E, Folsom AR, Juneja H. "Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease." Circulation. 2001;103(10):1386-9.
Wu C, Demerath EW, Pankow JS, et al. "Imputation of missing covariate values in epigenome-wide analysis of DNA methylation data." Epigenetics. 2016;11(2):132-9.
Wu A, Coresh JJ, Selvin E, et al. "Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community." J Am Heart Assoc. 2017;6(1).
Wright JD, Folsom AR, Coresh J, et al. "The ARIC (Atherosclerosis Risk In Communities) Study: JACC Focus Seminar 3/8." J Am Coll Cardiol. 2021;77(23):2939-2959.
Wormser D, White IR, Thompson SG. "Within-person variability in calculated risk factors: comparing the aetiological association of adiposity ratios with risk of coronary heart disease." Int J Epidemiol. 2013;42(3):849-59.
Wood AR, Esko T, Yang J, et al. "Defining the role of common variation in the genomic and biological architecture of adult human height." Nat Genet. 2014;46(11):1173-86.
Wong T Y, Shankar A, Klein R, et al. "Apolipoprotein E gene and early age-related maculopathy: the Atherosclerosis Risk in Communities Study." Ophthalmology. 2006;113(2):255-9.
Wong TY, Klein R, Couper DJ, et al. "Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study." Lancet. 2001;358(9288):1134-40.
Wong TY, Rosamond W, Chang PP, et al. "Retinopathy and risk of congestive heart failure." JAMA. 2005;293(1):63-9.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in Communities Study." Stroke. 2002;33(6):1487-92.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons." JAMA. 2002;287(19):2528-33.
Wong ND, Zhao Y, Patel R, et al. "Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study." Diabetes Care. 2016;39(5):668-76.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal arteriolar diameter and risk for hypertension." Ann Intern Med. 2004;140(4):248-55.
Wong T Y, Tikellis G, Sun C, Klein R, Couper DJ, A Sharrett R. "Age-related macular degeneration and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study." Ophthalmology. 2007;114(1):86-91.
Wong T Y, Klein R, Duncan BB, et al. "Racial differences in the prevalence of hypertensive retinopathy." Hypertension. 2003;41(5):1086-91.
Wong T Y, Coresh J, Klein R, et al. "Retinal microvascular abnormalities and renal dysfunction: the atherosclerosis risk in communities study." J Am Soc Nephrol. 2004;15(9):2469-76.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal arteriolar narrowing and risk of coronary heart disease in men and women. The Atherosclerosis Risk in Communities Study." JAMA. 2002;287(9):1153-9.
Wong TY, Klein R, Amirul Islam FM, et al. "Three-year incidence and cumulative prevalence of retinopathy: the atherosclerosis risk in communities study." Am J Ophthalmol. 2007;143(6):970-6.
Wong E, Ballew SH, Daya N, et al. "Hospitalization Risk among Older Adults with Chronic Kidney Disease." Am J Nephrol. 2019;50(3):212-220.
Wong T Y, Klein R, Nieto JF, et al. "Is early age-related maculopathy related to cognitive function? The Atherosclerosis Risk in Communities Study." Am J Ophthalmol. 2002;134(6):828-35.
Wong T Y, Duncan BB, Golden S H, et al. "Associations between the metabolic syndrome and retinal microvascular signs: the Atherosclerosis Risk In Communities study." Invest Ophthalmol Vis Sci. 2004;45(9):2949-54.
Wong TY, Mosley TH, Klein R, et al. "Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people." Neurology. 2003;61(6):806-11.
Wong T Y, Klein R, Sun C, et al. "Age-related macular degeneration and risk for stroke." Ann Intern Med. 2006;145(2):98-106.
Wong T Y, Klein R, A Sharrett R, et al. "Cerebral white matter lesions, retinopathy, and incident clinical stroke." JAMA. 2002;288(1):67-74.
Wojcik GL, Graff M, Nishimura KK, et al. "Genetic analyses of diverse populations improves discovery for complex traits." Nature. 2019;570(7762):514-518.
Wofford MR, Andrew ME, Brown A, et al. "Obesity Hypertension in the Atherosclerosis Risk in Communities Cohort: Implications of Obesity Guidelines." J Clin Hypertens (Greenwich). 1999;1(1):27-32.
Witt LS, Rotter J, Stearns SC, et al. "Heart Failure and Cognitive Impairment in the Atherosclerosis Risk in Communities (ARIC) Study." J Gen Intern Med. 2018;33(10):1721-1728.
Wirka RC, Gore S, Van Wagoner DR, et al. "A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation." Circ Arrhythm Electrophysiol. 2011;4(1):87-93.
Winkler TW, Justice AE, Graff M, et al. "Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2016;12(6):e1006166.
Winkler TW, Day FR, Croteau-Chonka DC, et al. "Quality control and conduct of genome-wide association meta-analyses." Nat Protoc. 2014;9(5):1192-212.
Winkler TW, Justice AE, Graff M, et al. "The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2015;11(10):e1005378.
Winkelman JW, Shahar E, Sharief I, Gottlieb DJ. "Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study." Neurology. 2008;70(1):35-42.
Winkelman JW, Redline S, Baldwin CM, Resnick HE, Newman AB, Gottlieb DJ. "Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health Study." Sleep. 2009;32(6):772-8.
B Windham G, Griswold ME, Wilkening SR, et al. "Midlife Smaller and Larger Infarctions, White Matter Hyperintensities, and 20-Year Cognitive Decline: A Cohort Study." Ann Intern Med. 2019;171(6):389-396.
B Windham G, Harrison KL, Lirette ST, et al. "Relationship Between Midlife Cardiovascular Health and Late-Life Physical Performance: The ARIC Study." J Am Geriatr Soc. 2017;65(5):1012-1018.
B Windham G, Griswold ME, Wang W, et al. "The Importance of Mid-to-Late-Life Body Mass Index Trajectories on Late-Life Gait Speed." J Gerontol A Biol Sci Med Sci. 2017;72(8):1130-1136.
Windham BG, Griswold ME, Shibata D, Penman A, Catellier DJ. "Covert neurological symptoms associated with silent infarcts from midlife to older age: the Atherosclerosis Risk in Communities study." Stroke. 2012;43(5):1218-23.
B Windham G, Deere B, Griswold ME, et al. "Small Brain Lesions and Incident Stroke and Mortality: A Cohort Study." Ann Intern Med. 2015;163(1):22-31.
B Windham G, Griswold ME, Lirette S, et al. "Effects of Age and Functional Status on the Relationship of Systolic Blood Pressure With Mortality in Mid and Late Life: The ARIC Study." J Gerontol A Biol Sci Med Sci. 2017;72(1):89-94.
Williams JE, Mosley TH, Kop WJ, Couper DJ, Welch VL, Rosamond WD. "Vital exhaustion as a risk factor for adverse cardiac events (from the Atherosclerosis Risk In Communities [ARIC] study)." Am J Cardiol. 2010;105(12):1661-5.
Williams JE, Massing M, Rosamond WD, Sorlie PD, Tyroler HA. "Racial disparities in CHD mortality from 1968-1992 in the state economic areas surrounding the ARIC study communities. Atherosclerosis Risk in Communities." Ann Epidemiol. 1999;9(8):472-80.
Williams JE, Nieto FJ, Sanford CP, Tyroler HA. "Effects of an angry temperament on coronary heart disease risk : The Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2001;154(3):230-5.
Williams JE, Din-Dzietham R, Szklo M. "Trait anger and arterial stiffness: results from the Atherosclerosis Risk in Communities (ARIC) study." Prev Cardiol. 2006;9(1):14-20.
Williams JE, Nieto JF, Sanford CP, Couper DJ, Tyroler HA. "The association between trait anger and incident stroke risk: the Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 2002;33(1):13-9.
Williams JE, Couper DJ, Din-Dzietham R, Nieto JF, Folsom AR. "Race-gender differences in the association of trait anger with subclinical carotid artery atherosclerosis: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2007;165(11):1296-304.
Williams JE, Johnson AM, Heiss G, Rose KM. "Association between exposure to combat-related stress and psychological health in aging men: the Atherosclerosis Risk in Communities (ARIC) Study." J Trauma Stress. 2010;23(3):358-66.
Williams JE, Paton CC, Siegler IC, Eigenbrodt ML, Nieto FJ, Tyroler HA. "Anger proneness predicts coronary heart disease risk: prospective analysis from the atherosclerosis risk in communities (ARIC) study." Circulation. 2000;101(17):2034-9.
Willems SM, Cornes BK, Brody JA, et al. "Association of the IGF1 gene with fasting insulin levels." Eur J Hum Genet. 2016;24(9):1337-43.
Willeit P, Kaptoge S, Welsh P, et al. "Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis." Lancet Diabetes Endocrinol. 2016;4(10):840-9.
Wild PS, Felix JF, Schillert A, et al. "Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function." J Clin Invest. 2017;127(5):1798-1812.
Whitsel EA, Rose KM, Wood JL, Henley AC, Liao D, Heiss G. "Accuracy and repeatability of commercial geocoding." Am J Epidemiol. 2004;160(10):1023-9.
Whitman IR, Vittinghoff E, Defilippi CR, et al. "NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure." J Am Heart Assoc. 2019;8(7):e010868.
White AD, Rosamond WD, Chambless LE, et al. "Sex and race differences in short-term prognosis after acute coronary heart disease events: the Atherosclerosis Risk In Communities (ARIC) study." Am Heart J. 1999;138(3 Pt 1):540-8.
White J, Beck CR, Harel T, et al. "POGZ truncating alleles cause syndromic intellectual disability." Genome Med. 2016;8(1):3.
White AD, Folsom AR, Chambless LE, et al. "Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: methods and initial two years' experience." J Clin Epidemiol. 1996;49(2):223-33.
White IR. "Covariate-adjusted measures of discrimination for survival data." Biom J. 2015;57(4):592-613.
Whelton SP, Roy P, Astor BC, Zhang L, Hoogeveen RC, Ballantyne CM. "Elevated high-sensitivity C-reactive protein as a risk marker of the attenuated relationship between serum cholesterol and cardiovascular events at older age. The ARIC Study." Am J Epidemiol. 2013;178(7):1076-84.
Whelton SP, McEvoy JW, Lazo M, Coresh JJ, Ballantyne CM. "High-Sensitivity Cardiac Troponin T (hs-cTnT) as a Predictor of Incident Diabetes in the Atherosclerosis Risk in Communities Study." Diabetes Care. 2017;40(2):261-269.
Wheeler E, Leong A, Liu C-T, et al. "Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis." PLoS Med. 2017;14(9):e1002383.
West NA, Johnson DA, Lutsey PL, Mosley TH, Redline S. "Cognition and 20-year subsequent sleep disturbances." Sleep Health. 2021.
West NA, B Windham G, Knopman DS, Shibata DK, Coker LH. "Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up." Neurology. 2019;92(9):e917-e923.
West NA, Tingle JV, Simino J, Selvin E, Bressler J. "The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity." Alzheimer Dis Assoc Disord. 2018;32(2):131-136.
Wessel J, Chu AY, Willems SM, et al. "Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility." Nat Commun. 2015;6:5897.
Weng L-C, Hall AWeber, Choi SHoan, et al. "Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation." Circ Genom Precis Med. 2020;13(5):387-395.
Weng L-C, Tang W, Rich SS, et al. "A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups." Thromb Res. 2014;134(2):462-7.
Weng L-C, Steffen LM, Szklo M, Nettleton J, Chambless L. "A diet pattern with more dairy and nuts, but less meat is related to lower risk of developing hypertension in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) study." Nutrients. 2013;5(5):1719-33.

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