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ARIC Publications

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Zubair N, Graff M, Ambite JLuis, et al. "Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci." Hum Mol Genet. 2016;25(24):5500-5512.
Zhu N, Pankow JS, Ballantyne CM, et al. "High-molecular-weight adiponectin and the risk of type 2 diabetes in the ARIC study." J Clin Endocrinol Metab. 2010;95(11):5097-104.
Zhou Q, Cai J. "Outcome-dependent sampling with interval-censored failure time data." Biometrics. 2018;74(1):58-67.
Zhou L, Stearns SC, Thudium EM, Alburikan KA. "Assessing Medicare Part D claim completeness using medication self-reports: the role of veteran status and Generic Drug Discount Programs." Med Care. 2015;53(5):463-70.
Zhou Z, Yu F, Buchanan A, et al. "Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts." PLoS One. 2014;9(1):e84810.
Zhong Y, Slade GD, Beck JD, Offenbacher S. "Gingival crevicular fluid interleukin-1beta, prostaglandin E2 and periodontal status in a community population." J Clin Periodontol. 2007;34(4):285-93.
Zheng Y, Yu B, Alexander D, et al. "Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study." Am J Epidemiol. 2013;178(4):534-42.
Zheng Z, Rebholz CM, Matsushita K, et al. "Survival advantage of cohort participation attenuates over time: results from three long-standing community-based studies." Ann Epidemiol. 2020;45:40-46.e4.
Zheng Y, Yu B, Alexander D, Steffen LM, Nettleton JA. "Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2014;99(6):1470-8.
Zheng Z-jie, Rosamond WD, Chambless LE, et al. "Lower extremity arterial disease assessed by ankle-brachial index in a middle-aged population of African Americans and whites: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Prev Med. 2005;29(5 Suppl 1):42-9.
Zheng ZJ, Folsom AR, Ma J, Arnett DK, McGovern PG, Eckfeldt JH. "Plasma fatty acid composition and 6-year incidence of hypertension in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1999;150(5):492-500.
Zheng Y, Yu B, Alexander D, Steffen LM. "Human metabolome associates with dietary intake habits among African Americans in the atherosclerosis risk in communities study." Am J Epidemiol. 2014;179(12):1424-33.
Zheng ZJ, Sharrett AR, Chambless LE, et al. "Associations of ankle-brachial index with clinical coronary heart disease, stroke and preclinical carotid and popliteal atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 1997;131(1):115-25.
Zheng Y, Yu B, Alexander D, Couper DJ. "Medium-term variability of the human serum metabolome in the Atherosclerosis Risk in Communities (ARIC) study." OMICS. 2014;18(6):364-73.
Zhao D, Bartz TM, Sotoodehnia N, et al. "Mitochondrial DNA copy number and incident atrial fibrillation." BMC Med. 2020;18(1):246.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
Zhao D, Post WS, Blasco-Colmenares E, et al. "Racial Differences in Sudden Cardiac Death." Circulation. 2019;139(14):1688-1697.
Zhao Y, Malik S, Budoff MJ, et al. "Identification and Predictors for Cardiovascular Disease Risk Equivalents among Adults With Diabetes Mellitus." Diabetes Care. 2021.
Zhao D, Guallar E, Vaidya D, et al. "Cyclic Guanosine Monophosphate and Risk of Incident Heart Failure and Other Cardiovascular Events: the ARIC Study." J Am Heart Assoc. 2020;9(2):e013966.
Zhao D, Guallar E, Ballantyne CM, et al. "Sex Hormones and Incident Heart Failure in Men and Postmenopausal Women: The Atherosclerosis Risk in Communities Study." J Clin Endocrinol Metab. 2020;105(10).
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Usefulness of electrocardiographic QRS/T angles with versus without bundle branch blocks to predict heart failure (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2014;114(3):412-8.
Zhang X, Farrell JJ, Tong T, et al. "Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease." Alzheimers Dement. 2021.
Zhang S, Divaris K, Moss K, et al. "The Novel Locus is Associated with Severe Gingival Inflammation." JDR Clin Trans Res. 2016;1(2):163-170.
Zhang S, Philips KH, Moss K, et al. "Periodontitis and Risk of Diabetes in the Atherosclerosis Risk In Communities (ARIC) Study: A BMI-modified Association." J Clin Endocrinol Metab. 2021.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Bundle branch blocks and the risk of mortality in the Atherosclerosis Risk in Communities study." J Cardiovasc Med (Hagerstown). 2016;17(6):411-7.
Zhang Y, Vittinghoff E, Pletcher MJ, et al. "Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events." J Am Coll Cardiol. 2019;74(3):330-341.
Zhang L, Spencer KL, V Voruganti S, et al. "Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study." Am J Epidemiol. 2013;177(9):923-32.
Zhang Y, Post WS, Dalal D, et al. "Serum 25-hydroxyvitamin D, calcium, phosphorus, and electrocardiographic QT interval duration: findings from NHANES III and ARIC." J Clin Endocrinol Metab. 2011;96(6):1873-82.
Zhang Y, Guallar E, Ashar FN, et al. "Association between mitochondrial DNA copy number and sudden cardiac death: findings from the Atherosclerosis Risk in Communities study (ARIC)." Eur Heart J. 2017;38(46):3443-3448.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Ventricular conduction defects and the risk of incident heart failure in the Atherosclerosis Risk in Communities (ARIC) Study." J Card Fail. 2015;21(4):307-12.
Zhang Z-M, Prineas RJ, Case D, Soliman EZ, Rautaharju PM. "Comparison of the prognostic significance of the electrocardiographic QRS/T angles in predicting incident coronary heart disease and total mortality (from the atherosclerosis risk in communities study)." Am J Cardiol. 2007;100(5):844-9.
Zhang MJ, Norby FL, Lutsey PL, et al. "Association of Left Atrial Enlargement and Atrial Fibrillation With Cognitive Function and Decline: The ARIC-NCS." J Am Heart Assoc. 2019;8(23):e013197.
Zhang Z-M, Rautaharju PM, Prineas RJ, Tereshchenko L. "Electrocardiographic QRS-T angle and the risk of incident silent myocardial infarction in the Atherosclerosis Risk in Communities study." J Electrocardiol. 2017;50(5):661-666.
Zhang L, Samet J, Caffo B, Punjabi NM. "Cigarette smoking and nocturnal sleep architecture." Am J Epidemiol. 2006;164(6):529-37.
Zhang L, Bůžková P, Wassel CL, et al. "Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study." Atherosclerosis. 2013;228(2):390-9.
Zhang Z-M, Rautaharju PM, Prineas RJ, Whitsel EA, Tereshchenko L. "A wide QRS/T angle in bundle branch blocks is associated with increased risk for coronary heart disease and all-cause mortality in the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2015;48(4):672-7.
Zhang Z-M, Rautaharju PM, Prineas RJ, et al. "Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(22):2141-8.
Zhang Z-M, Prineas RJ, Soliman EZ, Baggett C, Heiss G. "Prognostic significance of serial Q/ST-T changes by the Minnesota Code and Novacode in the Atherosclerosis Risk in Communities (ARIC) study." Eur J Prev Cardiol. 2012;19(6):1430-6.
Zewinger S, Kleber ME, Tragante V, et al. "Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study." Lancet Diabetes Endocrinol. 2017;5(7):534-543.
Zeng D, Gao F. "Maximum likelihood estimation for semiparametric regression models with multivariate interval-censored data." Biometrika. 2017;104(3):505-525.
Zanoni P, Khetarpal SA, Larach DB, et al. "Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease." Science. 2016;351(6278):1166-71.
Zakai NA, McClure LA, Judd SE, Safford MM, Folsom AR, Lutsey PL. "Racial and regional differences in venous thromboembolism in the United States in 3 cohorts." Circulation. 2014;129(14):1502-9.
Zakai NA, Ohira T, White R, Folsom AR, Cushman M. "Activated partial thromboplastin time and risk of future venous thromboembolism." Am J Med. 2008;121(3):231-8.
Zakai NA, Lutsey PL, Folsom AR, Heckbert SR, Cushman M. "Total tissue factor pathway inhibitor and venous thrombosis. The Longitudinal Investigation of Thromboembolism Etiology." Thromb Haemost. 2010;104(2):207-12.
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Yu B, Pulit SL, Hwang S-J, et al. "Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk." Circ Cardiovasc Genet. 2016;9(1):64-70.
Yu Z, Grams ME, Ndumele CE, et al. "Association Between Midlife Obesity and Kidney Function Trajectories: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2020.
Yu B, Flexeder C, McGarrah RW, et al. "Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population." Metabolites. 2019;9(4).
Yu B, Heiss G, Alexander D, Grams ME. "Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 2016;183(7):650-6.
Yu B, Li AH, Metcalf GA, et al. "Loss-of-function variants influence the human serum metabolome." Sci Adv. 2016;2(8):e1600800.
Yu B, Zheng Y, Alexander D, Morrison AC, Coresh JJ. "Genetic determinants influencing human serum metabolome among African Americans." PLoS Genet. 2014;10(3):e1004212.
Yu Z, Coresh JJ, Qi G, et al. "A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure." Kidney Int. 2020;98(3):708-716.
Yu B, Zheng Y, Nettleton JA, Alexander D, Coresh JJ. "Serum metabolomic profiling and incident CKD among African Americans." Clin J Am Soc Nephrol. 2014;9(8):1410-7.
Yu B, Roberts MB, Raffield LM, et al. "Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure." J Am Coll Cardiol. 2021;78(1):42-52.
Yu B, Zheng Y, Alexander D, Manolio TA, Alonso A, Nettleton JA. "Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study." Genet Epidemiol. 2013;37(8):840-5.
Yu B, Barbalic M, Brautbar A, et al. "Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies." Circ Cardiovasc Genet. 2013;6(1):82-8.
Yu B, de Vries PS, Metcalf GA, et al. "Whole genome sequence analysis of serum amino acid levels." Genome Biol. 2016;17(1):237.
Yu F, Lu J, Liu X, et al. "Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions." PLoS One. 2015;10(3):e0121644.
Yu B, Zanetti KA, Temprosa M, et al. "The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies." Am J Epidemiol. 2019;188(6):991-1012.
Yu B, Li AH, Muzny D, et al. "Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease." Circ Cardiovasc Genet. 2015;8(2):351-5.
Yu Z, Rebholz CM, Wong E, Chen Y, Matsushita K, Coresh JJ. "Association Between Hypertension and Kidney Function Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2019;74(3):310-319.
Young KL, Graff M, Fernández-Rhodes L. "Genetics of Obesity in Diverse Populations." Curr Diab Rep. 2018;18(12):145.
Young SE, Mainous AG, Carnemolla M. "Hyperinsulinemia and cognitive decline in a middle-aged cohort." Diabetes Care. 2006;29(12):2688-93.
Yong F, Heiss G, Couper DJ, Meyer ML, Cheng S. "Measurement Repeatability of Central and Peripheral Blood Pressures: The ARIC Study." Am J Hypertens. 2017;30(10):978-984.
Yoneyama S, Guo Y, Lanktree MB, et al. "Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations." Hum Mol Genet. 2014;23(9):2498-510.
Yoneyama S, Yao J, Guo X, et al. "Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations." Int J Obes (Lond). 2017;41(2):324-331.
Yi S-Y, Steffen LM, Lutsey PL, Cushman M, Folsom AR. "Contrasting Associations of Prudent and Western Dietary Patterns with Risk of Developing Venous Thromboembolism." Am J Med. 2021.
Yeung EH, Pankow JS, Astor BC, Powe NR, Saudek CD, Kao LWH. "Increased risk of type 2 diabetes from a family history of coronary heart disease and type 2 diabetes." Diabetes Care. 2007;30(1):154-6.
Yeung EH, Saudek CD, Jahren HA, et al. "Evaluation of a novel isotope biomarker for dietary consumption of sweets." Am J Epidemiol. 2010;172(9):1045-52.
Yende S, Alvarez K, Loehr L, et al. "Epidemiology and long-term clinical and biologic risk factors for pneumonia in community-dwelling older Americans: analysis of three cohorts." Chest. 2013;144(3):1008-1017.
Yeh H-C, Duncan BB, Schmidt M I, Wang N-Y, Brancati FL. "Smoking, smoking cessation, and risk for type 2 diabetes mellitus: a cohort study." Ann Intern Med. 2010;152(1):10-7.
Yeh H-C, Punjabi NM, Wang N-Y, Pankow JS, Duncan BB, Brancati FL. "Vital capacity as a predictor of incident type 2 diabetes: the Atherosclerosis Risk in Communities study." Diabetes Care. 2005;28(6):1472-9.
Yeh H-C, Punjabi NM, Wang N-Y, et al. "Cross-sectional and prospective study of lung function in adults with type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Diabetes Care. 2008;31(4):741-6.
Yee SWah, Stecula A, Chien H-C, et al. "Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies." PLoS Genet. 2019;15(9):e1008208.
Yeap BBeng, Marriott RJames, Adams RJ, et al. "Androgens In Men Study (AIMS): protocol for meta-analyses of individual participant data investigating associations of androgens with health outcomes in men." BMJ Open. 2020;10(5):e034777.
Yazdani A, Yazdani A, Samiei A. "Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data." J Biomed Inform. 2016;60:114-9.
Yazdani A, Yazdani A. "A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate." OMICS. 2016;20(8):480-4.
Yazdani A, Yazdani A, Samiei A. "Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study." J Biomed Inform. 2016;63:337-343.
Yazdani A, Yazdani A, Saniei A. "A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels." Metabolomics. 2016;12:104.
Yazdani A, Yazdani A. "Rare variants analysis using penalization methods for whole genome sequence data." BMC Bioinformatics. 2015;16:405.
Yazdani A, Yazdani A, Liu X. "Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis." Genet Epidemiol. 2016;40(6):486-91.

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