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ARIC Publications

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Kubota Y, Alonso A. "β-Thromboglobulin and incident cardiovascular disease risk: The Atherosclerosis Risk in Communities study." Thromb Res. 2017;155:116-120.
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Muntaner C, Nieto FJ, Cooper L, Meyer J, Szklo M, Tyroler HA. "Work organization and atherosclerosis: findings from the ARIC study. Atherosclerosis Risk in Communities." Am J Prev Med. 1998;14(1):9-18.
Rose KM, Carson AP, Catellier D, et al. "Women's employment status and mortality: the atherosclerosis risk in communities study." J Womens Health (Larchmt). 2004;13(10):1108-18.
Rose KM, Newman B, Tyroler HA, Szklo M, Arnett D, Srivastava N. "Women, employment status, and hypertension: cross-sectional and prospective findings from the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 1999;9(6):374-82.
Wormser D, White IR, Thompson SG. "Within-person variability in calculated risk factors: comparing the aetiological association of adiposity ratios with risk of coronary heart disease." Int J Epidemiol. 2013;42(3):849-59.
Zhang Z-M, Rautaharju PM, Prineas RJ, Whitsel EA, Tereshchenko L. "A wide QRS/T angle in bundle branch blocks is associated with increased risk for coronary heart disease and all-cause mortality in the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2015;48(4):672-7.
de Vries PS, Yu B, Feofanova EV, et al. "Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study." Hum Mol Genet. 2017;26(17):3442-3450.
Mikhaylova AV, McHugh CP, Polfus LM, et al. "Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program." Am J Hum Genet. 2021.
Hu Y, Stilp AM, McHugh CP, et al. "Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program." Am J Hum Genet. 2021;108(6):1165.
Morrison AC, Voorman A, Johnson AD, et al. "Whole-genome sequence-based analysis of high-density lipoprotein cholesterol." Nat Genet. 2013;45(8):899-901.
Cade BE, Lee J, Sofer T, et al. "Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program." Genome Med. 2021;13(1):136.
Farlow JL, Robak LA, Hetrick K, et al. "Whole-Exome Sequencing in Familial Parkinson Disease." JAMA Neurol. 2016;73(1):68-75.
Lange LA, Hu Y, Zhang H, et al. "Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol." Am J Hum Genet. 2014;94(2):233-45.
Polfus LM, Khajuria RK, Schick UM, et al. "Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis." Am J Hum Genet. 2016;99(2):481-8.
Vardarajan BN, Barral S, Jaworski J, et al. "Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease." Ann Clin Transl Neurol. 2018;5(4):406-417.
Yu B, de Vries PS, Metcalf GA, et al. "Whole genome sequence analysis of serum amino acid levels." Genome Biol. 2016;17(1):237.
Little A, Hu Y, Sun Q, et al. "Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative." Hum Mol Genet. 2021.
Lin BM, Grinde KE, Brody JA, et al. "Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium." EBioMedicine. 2021;63:103157.
Sarnowski C, Satizabal CL, DeCarli C, et al. "Whole genome sequence analyses of brain imaging measures in the Framingham Study." Neurology. 2018;90(3):e188-e196.
Bis JC, Jian X, Kunkle BW, et al. "Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation." Mol Psychiatry. 2020;25(8):1859-1875.
Lubitz SA, Brody JA, Bihlmeyer NA, et al. "Whole Exome Sequencing in Atrial Fibrillation." PLoS Genet. 2016;12(9):e1006284.
Simino J, Wang Z, Bressler J, et al. "Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study." PLoS One. 2017;12(7):e0180046.
Ma J, Rebholz CM, Braun KVE, et al. "Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality." Circ Genom Precis Med. 2020;13(4):e002766.
Hofer E, Cavalieri M, Bis JC, et al. "White Matter Lesion Progression: Genome-Wide Search for Genetic Influences." Stroke. 2015;46(11):3048-57.
Bekwelem W, Lutsey PL, Loehr LR, et al. "White blood cell count, C-reactive protein, and incident heart failure in the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 2011;21(10):739-48.
Lee CD, Folsom AR, Nieto FJ, Chambless LE, Shahar E, Wolfe DA. "White blood cell count and incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women: atherosclerosis risk in communities study." Am J Epidemiol. 2001;154(8):758-64.
Liu X, White S, Peng B, et al. "WGSA: an annotation pipeline for human genome sequencing studies." J Med Genet. 2016;53(2):111-2.
Ndumele CE, Cobb L, Lazo M, et al. "Weight History and Subclinical Myocardial Damage." Clin Chem. 2018;64(1):201-209.
French SA, Lutsey PL, Rosamond WD, Maclehose RF, Cushman M. "Weight change over 9 years and subsequent risk of venous thromboembolism in the ARIC cohort." Int J Obes (Lond). 2020;44(12):2465-2471.
Steven J, Chambless LE, Tyroler HA, Harp J, Jones D, Arnett D. "Weight change among self-reported dieters and non-dieters in white and African American men and women." Eur J Epidemiol. 2001;17(10):917-23.
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Shimakawa T, Nieto FJ, Malinow MR, Chambless LE, Schreiner PJ, Szklo M. "Vitamin intake: a possible determinant of plasma homocyst(e)ine among middle-aged adults." Ann Epidemiol. 1997;7(4):285-93.
Schneider ALC, Lutsey PL, Selvin E, et al. "Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: the Atherosclerosis Risk in Communities (ARIC) study." Eur J Neurol. 2015;22(8):1220-7.
Millen AE, Nie J, Sahli MW, et al. "Vitamin D Status and Prevalent Early Age-Related Macular Degeneration in African Americans and Caucasians: The Atherosclerosis Risk in Communities (ARIC) Study." J Nutr Health Aging. 2017;21(7):772-780.
Michos ED, Carson KA, Schneider ALC, et al. "Vitamin D and subclinical cerebrovascular disease: the Atherosclerosis Risk in Communities brain magnetic resonance imaging study." JAMA Neurol. 2014;71(7):863-71.
Schneider ALC, Lutsey PL, Alonso A, et al. "Vitamin D and cognitive function and dementia risk in a biracial cohort: the ARIC Brain MRI Study." Eur J Neurol. 2014;21(9):1211-8, e69-70.
Williams JE, Mosley TH, Kop WJ, Couper DJ, Welch VL, Rosamond WD. "Vital exhaustion as a risk factor for adverse cardiac events (from the Atherosclerosis Risk In Communities [ARIC] study)." Am J Cardiol. 2010;105(12):1661-5.
Bogle BM, Sotoodehnia N, Kucharska-Newton AMaria. "Vital exhaustion and sudden cardiac death in the Atherosclerosis Risk in Communities Study." Heart. 2018;104(5):423-429.
Cheung N, Rogers S, Mosley TH, Klein R, Couper D, Wong TY. "Vital exhaustion and retinal microvascular changes in cardiovascular disease: atherosclerosis risk in communities study." Psychosom Med. 2009;71(3):308-12.
Yeh H-C, Punjabi NM, Wang N-Y, Pankow JS, Duncan BB, Brancati FL. "Vital capacity as a predictor of incident type 2 diabetes: the Atherosclerosis Risk in Communities study." Diabetes Care. 2005;28(6):1472-9.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Ventricular conduction defects and the risk of incident heart failure in the Atherosclerosis Risk in Communities (ARIC) Study." J Card Fail. 2015;21(4):307-12.
Coady SA, A Sharrett R, Zheng Z-jie, Evans GW, Heiss G. "Vasectomy, inflammation, atherosclerosis and long-term followup for cardiovascular diseases: no associations in the atherosclerosis risk in communities study." J Urol. 2002;167(1):204-7.
Knopman DS, Penman AD, Catellier DJ, et al. "Vascular risk factors and longitudinal changes on brain MRI: the ARIC study." Neurology. 2011;76(22):1879-85.
Knopman DS, Griswold ME, Lirette ST, et al. "Vascular imaging abnormalities and cognition: mediation by cortical volume in nondemented individuals: atherosclerosis risk in communities-neurocognitive study." Stroke. 2015;46(2):433-40.
Logsdon BA, Dai JY, Auer PL, et al. "A variational Bayes discrete mixture test for rare variant association." Genet Epidemiol. 2014;38(1):21-30.
Riley WA, Evans GW, Sharrett AR, Burke GL, Barnes RW. "Variation of common carotid artery elasticity with intimal-medial thickness: the ARIC Study. Atherosclerosis Risk in Communities." Ultrasound Med Biol. 1997;23(2):157-64.
Folsom AR, Pankow JS, Peacock JM, Bielinski SJ, Heiss G, Boerwinkle E. "Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2008;31(5):905-9.
Foraker RE, Rose KM, Kucharska-Newton AM, Ni H, Suchindran CM, Whitsel EA. "Variation in rates of fatal coronary heart disease by neighborhood socioeconomic status: the atherosclerosis risk in communities surveillance (1992-2002)." Ann Epidemiol. 2011;21(8):580-8.
Folsom AR, Peacock JM, Boerwinkle E. "Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease." Atherosclerosis. 2009;202(1):211-5.
Folsom AR, Peacock JM, Demerath E, Boerwinkle E. "Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study." Metabolism. 2008;57(11):1591-6.
Pearte CA, Myerson M, Coresh J, et al. "Variation and temporal trends in the use of diagnostic testing during hospitalization for acute myocardial infarction by age, gender, race, and geography (the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2008;101(9):1219-25.
Lei HH, Coresh J, Shuldiner AR, Boerwinkle E, Brancati FL. "Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 1999;48(9):1868-72.
Luo S, Surapaneni A, Zheng Z, et al. "Variants, N-Acetylated Amino Acids, and Progression of CKD." Clin J Am Soc Nephrol. 2020;16(1):37-47.
Benjamin EJ, Rice KM, Arking DE, et al. "Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry." Nat Genet. 2009;41(8):879-81.
Shetty PB, Tang H, Feng T, et al. "Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families." Circ Cardiovasc Genet. 2015;8(1):106-13.
Afshar-Kharghan V, Matijevic-Aleksic N, Ahn C, Boerwinkle E, Wu KK, López JA. "The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease." Blood. 2004;103(3):963-5.
Arnett DK, Chambless LE, Kim H, Evans GW, Riley W. "Variability in ultrasonic measurements of arterial stiffness in the Atherosclerosis Risk in Communities study." Ultrasound Med Biol. 1999;25(2):175-80.
Chambless LE, Zhong MM, Arnett D, Folsom AR, Riley WA, Heiss G. "Variability in B-mode ultrasound measurements in the atherosclerosis risk in communities (ARIC) study." Ultrasound Med Biol. 1996;22(5):545-54.
Bhaskara S, Whitsel EA, Ballantyne CM. "Validity of self-report of lipid medication use: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2015;242(2):625-9.
Jones SA, Gottesman RF, Shahar E, Wruck L. "Validity of hospital discharge diagnosis codes for stroke: the Atherosclerosis Risk in Communities Study." Stroke. 2014;45(11):3219-25.
Schneider ALC, Pankow JS, Heiss G, Selvin E. "Validity and reliability of self-reported diabetes in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2012;176(8):738-43.
Wang HE, Donnelly JP, Yende S, et al. "Validation of the REGARDS Severe Sepsis Risk Score." J Clin Med. 2018;7(12).
Coady SA, Sorlie PD, Cooper LS, Folsom AR, Rosamond WD, Conwill DE. "Validation of death certificate diagnosis for coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study." J Clin Epidemiol. 2001;54(1):40-50.
Lusk CM, Dyson G, Clark AG, et al. "Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study." Hum Genet. 2014;133(9):1105-16.
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Bidulescu A, Chambless LE, Siega-Riz A M, Zeisel SH, Heiss G. "Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study." BMC Cardiovasc Disord. 2007;7:20.
Breslow NE, Lumley T, Ballantyne CM, Chambless LE, Kulich M. "Using the whole cohort in the analysis of case-cohort data." Am J Epidemiol. 2009;169(11):1398-405.
Tin A, Colantuoni E, Boerwinkle E, et al. "Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate." J Hum Genet. 2013;58(7):461-6.
Shungin D, Cornelis MC, Divaris K, et al. "Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium." Int J Epidemiol. 2015;44(2):638-50.
Massing MW, Simpson RJ, Rautaharju PM, Schreiner PJ, Crow R, Heiss G. "Usefulness of ventricular premature complexes to predict coronary heart disease events and mortality (from the Atherosclerosis Risk In Communities cohort)." Am J Cardiol. 2006;98(12):1609-12.
Soliman EZ, Zhang Z-M, Chen LYee, Tereshchenko LG, Arking D. "Usefulness of Maintaining a Normal Electrocardiogram Over Time for Predicting Cardiovascular Health." Am J Cardiol. 2017;119(2):249-255.
Hermida J, Lopez FL, Montes R, Matsushita K, Astor BC, Alonso A. "Usefulness of high-sensitivity C-reactive protein to predict mortality in patients with atrial fibrillation (from the Atherosclerosis Risk In Communities [ARIC] Study)." Am J Cardiol. 2012;109(1):95-9.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Usefulness of electrocardiographic QRS/T angles with versus without bundle branch blocks to predict heart failure (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2014;114(3):412-8.
Rodin AS, Litvinenko A, Klos K, et al. "Use of wrapper algorithms coupled with a random forests classifier for variable selection in large-scale genomic association studies." J Comput Biol. 2009;16(12):1705-18.
Kucharska-Newton AM, Loop MShane, Bullo M, et al. "Use of troponins in the classification of myocardial infarction from electronic health records. The Atherosclerosis Risk in Communities (ARIC) Study." Int J Cardiol. 2022;348:152-156.
Pendergrass SA, Brown-Gentry K, Dudek SM, et al. "The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery." Genet Epidemiol. 2011;35(5):410-22.
Kowalski MH, Qian H, Hou Z, et al. "Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations." PLoS Genet. 2019;15(12):e1008500.
Ray D, Pankow JS. "USAT: A Unified Score-Based Association Test for Multiple Phenotype-Genotype Analysis." Genet Epidemiol. 2016;40(1):20-34.
Köttgen A, Hwang S-J, Larson MG, et al. "Uromodulin levels associate with a common UMOD variant and risk for incident CKD." J Am Soc Nephrol. 2010;21(2):337-44.
Sekula P, Tin A, Schultheiss UT, et al. "Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease." Sci Rep. 2020;10(1):10018.
McMahon GM, Hwang S-J, Clish CB, et al. "Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease." Kidney Int. 2017;91(6):1426-1435.
Foster MC, Coresh JJ, Bonventre JV, et al. "Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(11):1956-63.

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