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ARIC Publications

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Journal Article
Singh GM, Danaei G, Farzadfar F, et al. "The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis." PLoS One. 2013;8(7):e65174.
C Quarta C, Buxbaum JN, Shah AM, et al. "The amyloidogenic V122I transthyretin variant in elderly black Americans." N Engl J Med. 2015;372(1):21-9.
Direk N, Williams S, Smith JA, et al. "An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype." Biol Psychiatry. 2017;82(5):322-329.
Li M, Li Y, Weeks O, et al. " and Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function." J Am Soc Nephrol. 2017;28(3):981-994.
Speliotes EK, Willer CJ, Berndt SI, et al. "Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index." Nat Genet. 2010;42(11):937-48.
Speliotes EK, Willer CJ, Berndt SI, et al. "Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index." Nat Genet. 2010;42(11):937-48.
Rosenthal EA, Makaryan V, Burt AA, et al. "Association Between Absolute Neutrophil Count and Variation at TCIRG1: The NHLBI Exome Sequencing Project." Genet Epidemiol. 2016;40(6):470-4.
Hao Q, Gottesman RF, Qiao Y, et al. "Association between kidney disease measures and intracranial atherosclerosis: The ARIC study." Neurology. 2020;94(22):e2361-e2372.
Huang T, Wang T, Zheng Y, et al. "Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study." JAMA Netw Open. 2019;2(9):e1910915.
Patel RS, Schmidt AF, Tragante V, et al. "Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events." Circ Genom Precis Med. 2019;12(4):e002471.
Peloso GM, Lange LA, Varga TV, et al. "Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study." Circ Cardiovasc Genet. 2016;9(4):368-74.
Gottesman RF, Mosley TH, Knopman DS, et al. "Association of Intracranial Atherosclerotic Disease With Brain β-Amyloid Deposition: Secondary Analysis of the ARIC Study." JAMA Neurol. 2020;77(3):350-357.
Quan SF, O'Connor GT, Quan JS, et al. "Association of physical activity with sleep-disordered breathing." Sleep Breath. 2007;11(3):149-57.
Quan SF, O'Connor GT, Quan JS, et al. "Association of physical activity with sleep-disordered breathing." Sleep Breath. 2007;11(3):149-57.
Naik RP, Derebail VK, Grams ME, et al. "Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans." JAMA. 2014;312(20):2115-25.
Clark DW, Okada Y, Moore KHS, et al. "Associations of autozygosity with a broad range of human phenotypes." Nat Commun. 2019;10(1):4957.
Kraja AT, Liu C, Fetterman JL, et al. "Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits." Am J Hum Genet. 2019;104(1):112-138.
Yu Z, Coresh JJ, Qi G, et al. "A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure." Kidney Int. 2020;98(3):708-716.
Teslovich TM, Musunuru K, Smith AV, et al. "Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
Kraja AT, Vaidya D, Pankow JS, et al. "A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium." Diabetes. 2011;60(4):1329-39.
Khalid U, Wruck LMiller, Quibrera PMiguel, et al. "BNP and obesity in acute decompensated heart failure with preserved vs. reduced ejection fraction: The Atherosclerosis Risk in Communities Surveillance Study." Int J Cardiol. 2017;233:61-66.
Caughey MC, Qiao Y, Windham BGwen, Gottesman RF, Mosley TH. "Carotid Intima-Media Thickness and Silent Brain Infarctions in a Biracial Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2018;31(8):869-875.
Suri FMK, Zhou J, Qiao Y, et al. "Cognitive impairment and intracranial atherosclerotic stenosis in general population." Neurology. 2018;90(14):e1240-e1247.
Suri FMK, Zhou J, Qiao Y, et al. "Cognitive impairment and intracranial atherosclerotic stenosis in general population." Neurology. 2018;90(14):e1240-e1247.
Deo R, Nalls MA, Avery CL, et al. "Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants." Heart Rhythm. 2013;10(3):401-8.
Assimes TL, Knowles JW, Priest JR, et al. "Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease." Hum Genet. 2008;123(4):399-408.
Do R, Willer CJ, Schmidt EM, et al. "Common variants associated with plasma triglycerides and risk for coronary artery disease." Nat Genet. 2013;45(11):1345-52.
Sotoodehnia N, Isaacs A, de Bakker PIW, et al. "Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction." Nat Genet. 2010;42(12):1068-76.
Etesami M, Hoi Y, Steinman DA, et al. "Comparison of carotid plaque ulcer detection using contrast-enhanced and time-of-flight MRA techniques." AJNR Am J Neuroradiol. 2013;34(1):177-84.
Nikpay M, Goel A, Won H-H, et al. "A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease." Nat Genet. 2015;47(10):1121-1130.
Nikpay M, Goel A, Won H-H, et al. "A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease." Nat Genet. 2015;47(10):1121-1130.
Yu B, Zanetti KA, Temprosa M, et al. "The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies." Am J Epidemiol. 2019;188(6):991-1012.
Winkler TW, Justice AE, Graff M, et al. "Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2016;12(6):e1006166.
Winkler TW, Justice AE, Graff M, et al. "Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2016;12(6):e1006166.
Sood SL, Cheng D, Ragni M, et al. "A cross-sectional analysis of cardiovascular disease in the hemophilia population." Blood Adv. 2018;2(11):1325-1333.
Wood AR, Esko T, Yang J, et al. "Defining the role of common variation in the genomic and biological architecture of adult human height." Nat Genet. 2014;46(11):1173-86.
Wood AR, Esko T, Yang J, et al. "Defining the role of common variation in the genomic and biological architecture of adult human height." Nat Genet. 2014;46(11):1173-86.
J Smith G, Felix JF, Morrison AC, et al. "Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure." PLoS Genet. 2016;12(5):e1006034.
van den Berg ME, Warren HR, Cabrera CP, et al. "Discovery of novel heart rate-associated loci using the Exome Chip." Hum Mol Genet. 2017;26(12):2346-2363.
Bis JC, Sitlani C, Irvin R, et al. "Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium." PLoS One. 2015;10(10):e0140496.
Arora S, Matsushita K, Qamar A, R Stacey B. "Early versus late percutaneous revascularization in patients hospitalized with non ST-segment elevation myocardial infarction: The atherosclerosis risk in communities surveillance study." Catheter Cardiovasc Interv. 2018;91(2):253-259.
Kapoor A, Sekar RB, Hansen NF, et al. "An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval." Am J Hum Genet. 2014;94(6):854-69.
Chu AY, Tin A, Schlosser P, et al. "Epigenome-wide association studies identify DNA methylation associated with kidney function." Nat Commun. 2017;8(1):1286.
Scott RA, Scott LJ, Mägi R, et al. "An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans." Diabetes. 2017;66(11):2888-2902.
Knowles JW, Assimes TL, Boerwinkle E, et al. "Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD." BMC Med Genet. 2008;9:23.
Howson JMM, Zhao W, Barnes DR, et al. "Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms." Nat Genet. 2017;49(7):1113-1119.
Howson JMM, Zhao W, Barnes DR, et al. "Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms." Nat Genet. 2017;49(7):1113-1119.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Zubair N, Graff M, Ambite JLuis, et al. "Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci." Hum Mol Genet. 2016;25(24):5500-5512.
Qi Q, Kilpeläinen TO, Downer MK, et al. "FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals." Hum Mol Genet. 2014;23(25):6961-72.
Qi Q, Kilpeläinen TO, Downer MK, et al. "FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals." Hum Mol Genet. 2014;23(25):6961-72.
Nettleton JA, Follis JL, Ngwa JS, et al. "Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry." Hum Mol Genet. 2015;24(16):4728-38.
Nettleton JA, Follis JL, Ngwa JS, et al. "Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry." Hum Mol Genet. 2015;24(16):4728-38.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Gaulton KJ, Ferreira T, Lee Y, et al. "Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci." Nat Genet. 2015;47(12):1415-25.
Sakornsakolpat P, Prokopenko D, Lamontagne M, et al. "Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations." Nat Genet. 2019;51(3):494-505.
Hobbs BD, de Jong K, Lamontagne M, et al. "Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nat Genet. 2017;49(3):426-432.
Kunkle BW, Grenier-Boley B, Sims R, et al. "Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing." Nat Genet. 2019;51(3):414-430.
Kunkle BW, Grenier-Boley B, Sims R, et al. "Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing." Nat Genet. 2019;51(3):414-430.
Kunkle BW, Grenier-Boley B, Sims R, et al. "Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing." Nat Genet. 2019;51(3):414-430.
Fesinmeyer MD, North KE, Ritchie MD, et al. "Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study." Obesity (Silver Spring). 2013;21(4):835-46.
Locke AE, Kahali B, Berndt SI, et al. "Genetic studies of body mass index yield new insights for obesity biology." Nature. 2015;518(7538):197-206.