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ARIC Publications

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2021
Palmer ND, Kahali B, Kuppa A, et al. "Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction." Hum Mol Genet. 2021;30(15):1443-1456.
Nichols E, Deal JA, Swenor BK, et al. "Assessing Bias in Cognitive Testing for Older Adults with Sensory Impairment: An Analysis of Differential Item Functioning in the Baltimore Longitudinal Study on Aging (BLSA) and the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Int Neuropsychol Soc. 2021:1-12.
Jia X, Sun C, Tanaka H, et al. "Association between circulating Galectin-3 and arterial stiffness in older adults." Vasa. 2021.
Jia X, Sun C, Tanaka H, et al. "Association between circulating Galectin-3 and arterial stiffness in older adults." Vasa. 2021.
Almuwaqqat Z, Claxton J'Neka S, Norby FL, et al. "Association of arterial stiffness with incident atrial fibrillation: a cohort study." BMC Cardiovasc Disord. 2021;21(1):247.
Wang W, Norby FL, George KM, et al. "Association of Carotid Intima-Media Thickness and Other Carotid Ultrasound Features With Incident Dementia in the ARIC-NCS." J Am Heart Assoc. 2021;10(9):e020489.
Georgakis MK, de Lemos JA, Ayers C, et al. "Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies." JAMA Cardiol. 2021;6(5):587-592.
Nji MAM, Solomon SD, Chen LYee, et al. "Association of heart failure subtypes and atrial fibrillation: Data from the Atherosclerosis Risk in Communities (ARIC) study." Int J Cardiol. 2021;339:47-53.
Garg PK, Norby FL, Wang W, et al. "Association of Longitudinal Changes in Cardiac Biomarkers With Atrial and Ventricular Arrhythmias (from the Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2021.
Hussain A, Sun W, Deswal A, et al. "Association of NT-ProBNP, Blood Pressure, and Cardiovascular Events: The ARIC Study." J Am Coll Cardiol. 2021;77(5):559-571.
Hussain A, Sun W, Deswal A, et al. "Association of NT-ProBNP, Blood Pressure, and Cardiovascular Events: The ARIC Study." J Am Coll Cardiol. 2021;77(5):559-571.
Maheshwari A, Norby FL, Soliman EZ, Alonso A, Sotoodehnia N, Chen LY. "Association of P-Wave Abnormalities With Sudden Cardiac and Cardiovascular Death: The ARIC Study." Circ Arrhythm Electrophysiol. 2021;14(2):e009314.
Hyacinth HI, Franceschini N, Seals SR, et al. "Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals." JAMA Netw Open. 2021;4(1):e2030435.
Brunner G, Virani SS, Sun W, et al. "Associations Between Carotid Artery Plaque Burden, Plaque Characteristics, and Cardiovascular Events: The ARIC Carotid Magnetic Resonance Imaging Study." JAMA Cardiol. 2021;6(1):79-86.
Nair N, Vittinghoff E, Pletcher MJ, et al. "Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes." J Clin Endocrinol Metab. 2021.
Nair N, Vittinghoff E, Pletcher MJ, et al. "Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes." J Clin Endocrinol Metab. 2021.
Sofer T, Lee J, Kurniansyah N, et al. "BinomiRare: A robust test for association of a rare genetic variant with a binary outcome for mixed models and any case-control proportion." HGG Adv. 2021;2(3).
Navas-Acien A, Domingo-Relloso A, Subedi P, et al. "Blood DNA Methylation and Incident Coronary Heart Disease: Evidence From the Strong Heart Study." JAMA Cardiol. 2021.
Northuis CA, Murray TA, Lutsey PL, et al. "Body mass index prediction rule for mid-upper arm circumference: the atherosclerosis risk in communities study." Blood Press Monit. 2021.
Northuis CA, Murray TA, Lutsey PL, et al. "Body mass index prediction rule for mid-upper arm circumference: the atherosclerosis risk in communities study." Blood Press Monit. 2021.
Johansen MC, Nyquist P, Sullivan KJ, Fornage M, Gottesman RF, Becker DM. "Cerebral Small-Vessel Disease in Individuals with a Family History of Coronary Heart Disease: The Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2021;55(4):316-322.
Natarajan P, Pampana A, Graham SE, et al. "Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices." Nat Commun. 2021;12(1):2182.
Natarajan P, Pampana A, Graham SE, et al. "Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices." Nat Commun. 2021;12(1):2182.
Natarajan P, Pampana A, Graham SE, et al. "Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices." Nat Commun. 2021;12(1):2182.
Natarajan P, Pampana A, Graham SE, et al. "Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices." Nat Commun. 2021;12(1):2182.
Goodrich JK, Singer-Berk M, Son R, et al. "Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes." Nat Commun. 2021;12(1):3505.
Segar MW, Jaeger BC, Patel KV, et al. "Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis." Circulation. 2021;143(24):2370-2383.
Segar MW, Jaeger BC, Patel KV, et al. "Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis." Circulation. 2021;143(24):2370-2383.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Echouffo-Tcheugui JB, Zhang S, Florido R, et al. "Duration of Diabetes and Incident Heart Failure: The ARIC (Atherosclerosis Risk In Communities) Study." JACC Heart Fail. 2021;9(8):594-603.
Echouffo-Tcheugui JB, Zhang S, Florido R, et al. "Duration of Diabetes and Incident Heart Failure: The ARIC (Atherosclerosis Risk In Communities) Study." JACC Heart Fail. 2021;9(8):594-603.
Saadati HMozafar, Sabour S, Mansournia MAli, Mehrabi Y, Nazari SSaeed Hash. "Effect modification of general and central obesity by sex and age on cardiovascular outcomes: Targeted maximum likelihood estimation in the atherosclerosis risk in communities study." Diabetes Metab Syndr. 2021;15(2):479-485.
Gondalia R, Baldassari A, Holliday KM, et al. "Epigenetically mediated electrocardiographic manifestations of sub-chronic exposures to ambient particulate matter air pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Res. 2021;198:111211.
Wang P, Castellani CA, Yao J, et al. "Epigenome-wide association study of mitochondrial genome copy number." Hum Mol Genet. 2021.
Thibord F, Song C, Pattee J, et al. FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer.. Vol. 19.; 2021. J Thromb Haemost 19(8).
Rooney MR, Norby FL, Maheshwari A, et al. "Frequent Premature Atrial Contractions Are Associated With Poorer Cognitive Function in the Atherosclerosis Risk in Communities (ARIC) Study." Mayo Clin Proc. 2021;96(5):1147-1156.
Ruth KS, Day FR, Hussain J, et al. "Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
Ruth KS, Day FR, Hussain J, et al. "Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
Ruth KS, Day FR, Hussain J, et al. "Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
Ruth KS, Day FR, Hussain J, et al. "Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
Ruth KS, Day FR, Hussain J, et al. "Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
Ruth KS, Day FR, Hussain J, et al. "Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
Ruth KS, Day FR, Hussain J, et al. "Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
Schunk SJ, Kleber ME, März W, et al. "Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality." Eur Heart J. 2021;42(18):1742-1756.
McCartney DL, Min JL, Richmond RC, et al. "Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging." Genome Biol. 2021;22(1):194.
McCartney DL, Min JL, Richmond RC, et al. "Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging." Genome Biol. 2021;22(1):194.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Jones G, Trajanoska K, Santanasto AJ, et al. "Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
Echouffo-Tcheugui JB, Daya N, Matsushita K, et al. "Growth Differentiation Factor (GDF)-15 and Cardiometabolic Outcomes among Older Adults: The Atherosclerosis Risk in Communities Study." Clin Chem. 2021;67(4):653-661.
Commodore-Mensah Y, Lazo M, Tang O, et al. "High Burden of Subclinical and Cardiovascular Disease Risk in Adults with Metabolically Healthy Obesity: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2021.
Commodore-Mensah Y, Lazo M, Tang O, et al. "High Burden of Subclinical and Cardiovascular Disease Risk in Adults with Metabolically Healthy Obesity: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2021.
Qi Q, Li J, Yu B, et al. "Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies." Gut. 2021.
Sullivan KJ, Ranadive R, Su D, et al. "Imaging-based indices of Neuropathology and gait speed decline in older adults: the atherosclerosis risk in communities study." Brain Imaging Behav. 2021.
Narayan KMVenkat, Kondal D, Daya N, et al. "Incidence and pathophysiology of diabetes in South Asian adults living in India and Pakistan compared with US blacks and whites." BMJ Open Diabetes Res Care. 2021;9(1).
Narayan KMVenkat, Kondal D, Kobes S, et al. "Incidence of diabetes in South Asian young adults compared to Pima Indians." BMJ Open Diabetes Res Care. 2021;9(1).
Sarnowski C, Cousminer DL, Franceschini N, et al. "Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
Krishnappa D, Wang W, Rooney MR, et al. "Life's Simple 7 cardiovascular health score and premature atrial contractions: The atherosclerosis risk in communities (ARIC) study." Int J Cardiol. 2021.
Xu H, Schwander K, Brown MR, et al. "Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions." Eur J Hum Genet. 2021;29(5):839-850.