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Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies.

TitleImplications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies.
Publication TypeJournal Article
Year of Publication1991
AuthorsFolsom AR, Burke GL, Byers CL, Hutchinson RG, Heiss G, Flack JM, Jacobs DR, Caan B
JournalAm J Clin Nutr
Volume53
Issue6 Suppl
Pagination1604S-1611S
Date Published1991 06
ISSN0002-9165
KeywordsAdolescent, Adult, African Americans, Aged, Body Composition, Body Mass Index, Cardiovascular Diseases, Diabetes Mellitus, Female, Health Status Indicators, Humans, Male, Middle Aged, Obesity, Prevalence, Prospective Studies, Risk Factors, United States
Abstract

To examine the relation of obesity to cardiovascular disease in blacks, we analyzed data from two population studies, including young and middle-aged adults. Obesity, defined by using the sum of subscapular and triceps skinfold measurements, was positively associated with atherogenic plasma lipids, systolic blood pressure, serum glucose and insulin, and prevalence of diabetes mellitus. The strength of these associations, for the most part, was similar in blacks and whites. However, with each unit increase in sum of skinfold thicknesses, plasma triglyceride concentrations in blacks appeared to increase only one-third to one-half as much as in whites. Prevalence of cardiovascular disease in 45- to 65-y-old blacks was associated with obesity; the odds ratio (95% confidence interval), adjusted for age and cigarette smoking, was 1.3 (0.9, 1.8) in both black men and black women. Additional analyses showed that abdominal adiposity conferred increased risk. These findings suggest that both blacks and whites should avoid excess adiposity.

DOI10.1093/ajcn/53.6.1604S
Alternate JournalAm J Clin Nutr
PubMed ID2031493
Grant ListN01-HC-48047 / HC / NHLBI NIH HHS / United States
N01-HC-48048 / HC / NHLBI NIH HHS / United States
N01-HC-48049 / HC / NHLBI NIH HHS / United States