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Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women. The Atherosclerosis Risk in Communities (ARIC) Study.

TitleAssociation of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women. The Atherosclerosis Risk in Communities (ARIC) Study.
Publication TypeJournal Article
Year of Publication1995
AuthorsSharrett AR, Chambless LE, Heiss G, Paton CC, Patsch W
JournalArterioscler Thromb Vasc Biol
Volume15
Issue12
Pagination2122-9
Date Published1995 Dec
ISSN1079-5642
KeywordsAfrican Continental Ancestry Group, Apolipoprotein B-48, Apolipoproteins B, Arteriosclerosis, Carotid Artery Diseases, Carotid Stenosis, Coronary Disease, Dietary Fats, Diterpenes, European Continental Ancestry Group, Female, Humans, Male, Middle Aged, Obesity, Retinyl Esters, Triglycerides, Vitamin A
Abstract

Blood lipid alterations after a fatty meal may be atherogenic, but there is little information regarding their associations with disease independent of fasting lipids. Asymptomatic atherosclerosis cases (n = 229) and 373 control subjects free of atherosclerosis, as defined by carotid intima-media thickness on ultrasound images, were given a fatty meal with vitamin A, followed by 3.5- and 8-hour measurements of triglycerides (TGs), TG-rich lipoprotein TGs, apoproteinB48, and retinyl palmitate. Among white men and women but not among blacks, case status was associated with greater postprandial responses of TGs and TG-rich lipoprotein TGs, but only in nonobese persons (body mass index

DOI10.1161/01.atv.15.12.2122
Alternate JournalArterioscler Thromb Vasc Biol
PubMed ID7489232
Grant ListN01-HC55015 / HC / NHLBI NIH HHS / United States
N01-HC55016 / HC / NHLBI NIH HHS / United States
UO1 HL45467 / HL / NHLBI NIH HHS / United States