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Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women. The Atherosclerosis Risk in Communities (ARIC) Study.

TitleAssociation of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women. The Atherosclerosis Risk in Communities (ARIC) Study.
Publication TypeJournal Article
Year of Publication1995
AuthorsSharrett AR, Chambless LE, Heiss G, Paton CC, Patsch W
JournalArterioscler Thromb Vasc Biol
Volume15
Issue12
Pagination2122-9
Date Published1995 Dec
ISSN1079-5642
KeywordsApolipoprotein B-48, Apolipoproteins B, Arteriosclerosis, Blacks, Carotid Artery Diseases, Carotid Stenosis, Coronary Disease, Dietary Fats, Diterpenes, Female, Humans, Male, Middle Aged, Obesity, Retinyl Esters, Triglycerides, Vitamin A, Whites
Abstract

Blood lipid alterations after a fatty meal may be atherogenic, but there is little information regarding their associations with disease independent of fasting lipids. Asymptomatic atherosclerosis cases (n = 229) and 373 control subjects free of atherosclerosis, as defined by carotid intima-media thickness on ultrasound images, were given a fatty meal with vitamin A, followed by 3.5- and 8-hour measurements of triglycerides (TGs), TG-rich lipoprotein TGs, apoproteinB48, and retinyl palmitate. Among white men and women but not among blacks, case status was associated with greater postprandial responses of TGs and TG-rich lipoprotein TGs, but only in nonobese persons (body mass index

DOI10.1161/01.atv.15.12.2122
Alternate JournalArterioscler Thromb Vasc Biol
PubMed ID7489232
Grant ListN01-HC55015 / HC / NHLBI NIH HHS / United States
N01-HC55016 / HC / NHLBI NIH HHS / United States
UO1 HL45467 / HL / NHLBI NIH HHS / United States