Pulse lineResearch With Heart Logo

Black-white differences in electrocardiographic left ventricular mass and its association with blood pressure (the ARIC study). Atherosclerosis Risk in Communities.

TitleBlack-white differences in electrocardiographic left ventricular mass and its association with blood pressure (the ARIC study). Atherosclerosis Risk in Communities.
Publication TypeJournal Article
Year of Publication1994
AuthorsArnett DK, Rautaharju P, Crow R, Folsom AR, Ekelund LG, Hutchinson R, Tyroler HA, Heiss G
JournalAm J Cardiol
Volume74
Issue3
Pagination247-52
Date Published1994 Aug 01
ISSN0002-9149
KeywordsAfrican Continental Ancestry Group, Antihypertensive Agents, Blood Pressure, Body Weight, Chi-Square Distribution, Cohort Studies, Electrocardiography, European Continental Ancestry Group, Female, Humans, Hypertension, Hypertrophy, Left Ventricular, Male, Middle Aged, Prognosis, Prospective Studies, Regression Analysis, Risk Factors
Abstract

Black-white differences in the association between antihypertensive therapy, continuous measures of mean arterial and pulse pressures and left ventricular (LV) mass estimated from a multivariable electrocardiographic algorithm were examined in 6,020 men (23% black) and 7,970 women (29% black) participating in the Atherosclerosis Risk in Communities (ARIC) study. Mean arterial and pulse pressures, weight, the percentage of subjects taking antihypertensive medication, and LV mass were higher in black than in white men (98 vs 89 mm Hg, 47 vs 46 mm Hg, 188 vs 187 pounds, 30% vs 17%, and 243 vs 217 g, respectively). Results of similar direction but greater magnitude were observed in black versus white women (mean arterial pressure, 94 vs 85 mm Hg; pulse pressure, 50 vs 47 mm Hg; weight, 180 vs 153 pounds; percent treated, 42% vs 18%; and LV mass, 203 vs 169 g, respectively). In multivariable regression analyses, blacks had higher levels of LV mass, and LV mass increased more sharply with increasing mean arterial pressure in blacks than in whites after adjusting for age, pulse pressure, and weight. At equal mean arterial and pulse pressures, age, and weight, treated blacks had higher LV mass than treated whites. These data indicate that blacks have higher LV mass than whites, and a more pronounced blood pressure-LV mass relation after controlling for other risk factors and treatment status. Given the prognostic importance of LV hypertrophy,

DOI10.1016/0002-9149(94)90365-4
Alternate JournalAm J Cardiol
PubMed ID8037129
Grant ListN01-HC-55015 / HC / NHLBI NIH HHS / United States
N01-HC-55016 / HC / NHLBI NIH HHS / United States
N01-HC-55017 / HC / NHLBI NIH HHS / United States