| Title | Antigens of tissue plasminogen activator and plasminogen activator inhibitor 1: correlates in nonsmoking Japanese and Caucasian men and women. |
| Publication Type | Journal Article |
| Year of Publication | 1993 |
| Authors | Iso H, Folsom AR, Koike KA, Sato S, Wu KK, Shimamoto T, Iida M, Komachi Y |
| Journal | Thromb Haemost |
| Volume | 70 |
| Issue | 3 |
| Pagination | 475-80 |
| Date Published | 1993 Sep 01 |
| ISSN | 0340-6245 |
| Keywords | Aged, Antigens, Asian People, Coronary Disease, Female, Humans, Japan, Male, Middle Aged, Plasminogen Activator Inhibitor 1, Risk Factors, Sex Characteristics, Tissue Plasminogen Activator, White People |
| Abstract | We reported in a 1987 preliminary study that tissue plasminogen activator antigen was significantly higher in American Caucasian men than in Japanese men. To further examine possible differences in fibrinolytic activity between the two races, an expanded study was conducted in a total of 300 nonsmoking men and women aged 47-69 years in two population-based samples: rural Japanese living in Akita and Caucasians living in Minneapolis-St. Paul, MN. Antigens of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) were measured. Mean t-PA antigen was 2.3 ng/ml higher in Caucasian men than in Japanese men (P |
| Alternate Journal | Thromb Haemost |
| PubMed ID | 8259552 |
| Grant List | N01-HC-55019 / HC / NHLBI NIH HHS / United States |