Pulse lineResearch With Heart Logo

Plasma fibrinogen and its correlates in Japanese and US population samples.

TitlePlasma fibrinogen and its correlates in Japanese and US population samples.
Publication TypeJournal Article
Year of Publication1993
AuthorsIso H, Folsom AR, Sato S, Wu KK, Shimamoto T, Koike K, Iida M, Komachi Y
JournalArterioscler Thromb
Volume13
Issue6
Pagination783-90
Date Published1993 Jun
ISSN1049-8834
KeywordsAfrican Continental Ancestry Group, Asian Continental Ancestry Group, Coronary Disease, European Continental Ancestry Group, Female, Fibrinogen, Humans, Japan, Male, Middle Aged, Risk Factors, Smoking, United States
Abstract

In a preliminary 1987 study, we reported that the plasma fibrinogen level was significantly higher in Caucasian American men than Japanese men. To confirm this finding, we used data from 1,020 Japanese men and women in a 1989-1991 Akita, Japan, population study and from > 15,000 men and women from the 1986-1989 Atherosclerosis Risk in Communities (ARIC) Study. To examine further the correlates of plasma fibrinogen level, subsamples of nonsmoking Akita Japanese (n = 150) and Minneapolis Caucasians (n = 150) were also studied separately in 1990. Compared with the Japanese in the Akita study, Caucasians and African Americans in ARIC had a 23-40 mg/dL higher age-adjusted fibrinogen level for men and a 25-67 mg/dL higher level for women. In the subsample, the mean plasma fibrinogen value was 288 mg/dL in Caucasian men and 248 mg/dL in Japanese men (test for difference: p

DOI10.1161/01.atv.13.6.783
Alternate JournalArterioscler Thromb
PubMed ID8499398
Grant ListN01-HC-55015 / HC / NHLBI NIH HHS / United States
N01-HC-55016 / HC / NHLBI NIH HHS / United States
N01-HC-55018 / HC / NHLBI NIH HHS / United States