| Title | Lipoprotein[a] as a risk factor for preclinical atherosclerosis. |
| Publication Type | Journal Article |
| Year of Publication | 1993 |
| Authors | Schreiner PJ, Morrisett JD, Sharrett AR, Patsch W, Tyroler HA, Wu K, Heiss G |
| Journal | Arterioscler Thromb |
| Volume | 13 |
| Issue | 6 |
| Pagination | 826-33 |
| Date Published | 1993 Jun |
| ISSN | 1049-8834 |
| Keywords | Arteriosclerosis, Black People, Carotid Arteries, Cholesterol, LDL, Female, Humans, Lipoprotein(a), Male, Middle Aged, Prospective Studies, Risk Factors, White People |
| Abstract | Elevated mean levels of lipoprotein[a] (Lp[a]) have been associated with symptomatic cardiovascular diseases such as clinically manifest myocardial infarction (MI), coronary artery disease, restenosis of coronary artery vein grafts after bypass, and a family history of MI. Associations of Lp[a] with arterial wall thickening in asymptomatic individuals previously have not been addressed and are evaluated in this report among participants of the Atherosclerosis Risk in Communities (ARIC) Study. Intima-media wall thickening in the extracranial carotid arteries was assessed noninvasively with B-mode ultrasonography; Lp[a] was measured as its total protein component. Individuals with wall thickening > or = 90th percentile of the population maximum far-wall thickness were pair matched to participants |
| DOI | 10.1161/01.atv.13.6.826 |
| Alternate Journal | Arterioscler Thromb |
| PubMed ID | 8499402 |
| Grant List | 1-HC-55019 / HC / NHLBI NIH HHS / United States |