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A metabolic syndrome in whites and African-Americans. The Atherosclerosis Risk in Communities baseline study.

TitleA metabolic syndrome in whites and African-Americans. The Atherosclerosis Risk in Communities baseline study.
Publication TypeJournal Article
Year of Publication1996
AuthorsSchmidt MI, Duncan BB, Watson RL, Sharrett AR, Brancati FL, Heiss G
JournalDiabetes Care
Volume19
Issue5
Pagination414-8
Date Published1996 May
ISSN0149-5992
KeywordsArteriosclerosis, Blacks, Cholesterol, HDL, Cluster Analysis, Diabetes Mellitus, Ethnicity, Female, Humans, Hypertension, Hypertriglyceridemia, Insulin, Male, Middle Aged, Probability, Risk Factors, Sex Characteristics, United States, Uric Acid, Whites
Abstract

OBJECTIVE: To describe clustering of hypertriglyceridemia, low HDL cholesterol, hypertension, diabetes, and hyperuricemia and its association with fasting insulin, waist-to-hip ratio (WHR), and BMI for African-American and white men and women.

RESEARCH DESIGN AND METHODS: Observed frequencies of clusters were compared with those expected in 14,481 participants, 45-64 years of age, of the Atherosclerosis Risk in Communities (ARIC) baseline survey, 1987-1989. Associations of clusters with insulin, central adiposity, and overall obesity, as well as with abnormalities, were analyzed through multiple logistic regression.

RESULTS: Clustering beyond chance was observed in all four sex/ethnic groups (P or = 3 abnormalities per individual). The odds ratio (OR) for the association of each abnormality with clustering of the remaining four ranged from 1.6 to 8.8 (P

DOI10.2337/diacare.19.5.414
Alternate JournalDiabetes Care
PubMed ID8732701