|Title||A metabolic syndrome in whites and African-Americans. The Atherosclerosis Risk in Communities baseline study.|
|Publication Type||Journal Article|
|Year of Publication||1996|
|Authors||Schmidt MI, Duncan BB, Watson RL, Sharrett AR, Brancati FL, Heiss G|
|Date Published||1996 May|
|Keywords||African Continental Ancestry Group, Arteriosclerosis, Cholesterol, HDL, Cluster Analysis, Diabetes Mellitus, Ethnic Groups, European Continental Ancestry Group, Female, Humans, Hypertension, Hypertriglyceridemia, Insulin, Male, Middle Aged, Probability, Risk Factors, Sex Characteristics, United States, Uric Acid|
OBJECTIVE: To describe clustering of hypertriglyceridemia, low HDL cholesterol, hypertension, diabetes, and hyperuricemia and its association with fasting insulin, waist-to-hip ratio (WHR), and BMI for African-American and white men and women.
RESEARCH DESIGN AND METHODS: Observed frequencies of clusters were compared with those expected in 14,481 participants, 45-64 years of age, of the Atherosclerosis Risk in Communities (ARIC) baseline survey, 1987-1989. Associations of clusters with insulin, central adiposity, and overall obesity, as well as with abnormalities, were analyzed through multiple logistic regression.
RESULTS: Clustering beyond chance was observed in all four sex/ethnic groups (P or = 3 abnormalities per individual). The odds ratio (OR) for the association of each abnormality with clustering of the remaining four ranged from 1.6 to 8.8 (P
|Alternate Journal||Diabetes Care|