| Title | Association of transient ischemic attack/stroke symptoms assessed by standardized questionnaire and algorithm with cerebrovascular risk factors and carotid artery wall thickness. The ARIC Study, 1987-1989. |
| Publication Type | Journal Article |
| Year of Publication | 1996 |
| Authors | Chambless LE, Shahar E, Sharrett AR, Heiss G, Wijnberg L, Paton CC, Sorlie P, Toole JF |
| Journal | Am J Epidemiol |
| Volume | 144 |
| Issue | 9 |
| Pagination | 857-66 |
| Date Published | 1996 Nov 01 |
| ISSN | 0002-9262 |
| Keywords | Algorithms, Carotid Arteries, Cerebrovascular Disorders, Cohort Studies, Cross-Sectional Studies, Female, Humans, Ischemic Attack, Transient, Logistic Models, Male, Middle Aged, Prevalence, Risk Factors, Sex Factors, Socioeconomic Factors, Surveys and Questionnaires, Ultrasonography, United States |
| Abstract | The baseline examination (1987-1989) for the Atherosclerosis Risk in Communities (ARIC) Study was conducted in 15,792 free-living residents aged 45-64 years in four geographically dispersed US communities. A questionnaire on symptoms of transient ischemic attack (TIA) and stroke was evaluated by computer algorithm for 12,205 of these participants. Data were also collected on lipoprotein levels, hemostasis, hematology, anthropometry, blood pressure, medical history, lifestyle, socioeconomic status, and medication use. Noninvasive high resolution B-mode ultrasonographic imaging was used to determine carotid arterial intimal-medial wall thickness (IMT). The cross-sectional relation between the prevalence of TIA/stroke symptoms and putative risk factors was assessed by logistic regression, controlling for age and community. Odds ratios for TIA/stroke symptoms were significantly elevated (p |
| DOI | 10.1093/oxfordjournals.aje.a009020 |
| Alternate Journal | Am J Epidemiol |
| PubMed ID | 8890664 |
| Grant List | N01-HC-55015 / HC / NHLBI NIH HHS / United States |