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Reproducibility of extracranial carotid atherosclerotic lesions assessed by B-mode ultrasound: the Atherosclerosis Risk in Communities Study.

TitleReproducibility of extracranial carotid atherosclerotic lesions assessed by B-mode ultrasound: the Atherosclerosis Risk in Communities Study.
Publication TypeJournal Article
Year of Publication1996
AuthorsLi R, Cai J, Tegeler C, Sorlie P, Metcalf PA, Heiss G
JournalUltrasound Med Biol
Volume22
Issue7
Pagination791-9
Date Published1996
ISSN0301-5629
KeywordsAged, Arteriosclerosis, Body Mass Index, Carotid Arteries, Carotid Artery Diseases, Cohort Studies, Confidence Intervals, Female, Humans, Male, Middle Aged, Observer Variation, Reproducibility of Results, Ultrasonography
Abstract

The reproducibility in the identification of carotid artery lesions using B-mode ultrasound was studied in a large random sample selected from the Atherosclerosis Risk in Communities (ARIC) Study. Carotid lesions were defined as plaque with or without acoustic shadowing (indicative of mineralization). A weighted kappa (kappa w) statistic was used as a chance-adjusted measure of repeatability. In the ARIC baseline survey, the kappa w values for the assessment of lesions on repeat reading were 0.47, 0.60 and 0.69 in the left common carotid artery, the carotid bifurcation and the internal carotid artery, respectively. In a repeat scanning, the kappa w values ranged from 0.59 to 0.79 in the left carotid segments. The results were similar in the left and right carotid arteries. Covariates (age, race, gender, body mass index, study center) did not influence the reproducibility. Similar results were also found in both the baseline survey and the first follow-up examination. In conclusion, reproducibility in the assessment of carotid lesions by B-mode ultrasound can be achieved in multicenter studies at fair to good levels of agreement.

DOI10.1016/0301-5629(96)00084-1
Alternate JournalUltrasound Med Biol
PubMed ID8923698
Grant ListN01-HC-55015 / HC / NHLBI NIH HHS / United States
N01-HC-55018 / HC / NHLBI NIH HHS / United States
N01-HC-55019 / HC / NHLBI NIH HHS / United States