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Body mass index, waist/hip ratio, and coronary heart disease incidence in African Americans and whites. Atherosclerosis Risk in Communities Study Investigators.

TitleBody mass index, waist/hip ratio, and coronary heart disease incidence in African Americans and whites. Atherosclerosis Risk in Communities Study Investigators.
Publication TypeJournal Article
Year of Publication1998
AuthorsFolsom AR, Stevens J, Schreiner PJ, McGovern PG
JournalAm J Epidemiol
Volume148
Issue12
Pagination1187-94
Date Published1998 Dec 15
ISSN0002-9262
KeywordsAfrican Americans, African Continental Ancestry Group, Body Constitution, Body Mass Index, Coronary Disease, European Continental Ancestry Group, Female, Humans, Incidence, Male, Maryland, Middle Aged, Minnesota, Mississippi, North Carolina, Obesity, Prospective Studies, Risk, Sex Distribution
Abstract

To study the relation of the amount and distribution of body fat with incident coronary heart disease in two ethnic groups, the authors analyzed prospective data from the Atherosclerosis Risk in Communities Study. Among 14,040 participants aged 45-64 years and free of coronary disease at baseline in 1987-1989, we identified 398 events through 1994, an average of 6.2 years of follow-up. Among African-American women, the multivariable-adjusted relative risks of coronary heart disease across quartiles of body mass index were 1.0, 1.91. 1.54, and 2.15 (p for trend=0.27), and those for waist/hip ratio were 1.0, 2.07, 2.33, and 4.22 (p for trend=0.02). Among African-American men, these respective relative risks were 1.0, 1.03, 0.83, and 1.20 (p for trend=0.76) for body mass index and 1.0, 1.08, 1.87, and 1.68 (p for trend=0.06) for waist/hip ratio. Relative risks for whites were generally similar to those for African Americans. Relative risks were stronger for never smokers than for the overall cohort. Unlike some previous studies, our results suggest that Africa Americans, like whites, are not spared from the coronary heart disease risks accompanying obesity.

DOI10.1093/oxfordjournals.aje.a009608
Alternate JournalAm J Epidemiol
PubMed ID9867265
Grant ListN01-HC-55015 / HC / NHLBI NIH HHS / United States
N01-HC-55016 / HC / NHLBI NIH HHS / United States
N01-HC-55018 / HC / NHLBI NIH HHS / United States