| Title | Dietary antioxidant intake and cognitive performance in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study investigators. |
| Publication Type | Journal Article |
| Year of Publication | 2000 |
| Authors | Peacock JM, Folsom AR, Knopman DS, Mosley TH, Goff DC, Szklo M |
| Journal | Public Health Nutr |
| Volume | 3 |
| Issue | 3 |
| Pagination | 337-43 |
| Date Published | 2000 Sep |
| ISSN | 1368-9800 |
| Keywords | Aged, Antioxidants, Ascorbic Acid, Carotenoids, Cognition, Cognition Disorders, Cohort Studies, Cross-Sectional Studies, Dietary Supplements, Female, Humans, Male, Middle Aged, Multicenter Studies as Topic, Prospective Studies, Surveys and Questionnaires, Vitamin E |
| Abstract | OBJECTIVE: To assess the cross-sectional association of dietary and supplemental antioxidant (carotenoids, vitamins C and E) intake with cognitive function in 12 187 individuals, aged 48-67 years, participating in the Atherosclerosis Risk in Communities (ARIC) Study. METHODS: Dietary intake of antioxidant vitamins, as assessed by a food frequency questionnaire, and use of supplements were analysed in relation to the results of three cognitive tests, the delayed word recall test, the Wechsler adult intelligence scale, revised (WAIS-R) digit symbol subtest and the word fluency test. RESULTS: After adjustment for covariates previously found to be associated with cognition in this sample, we found no consistent associations between dietary antioxidant vitamin intake or supplement use and any of the cognitive tests. CONCLUSIONS: This study suggests little, if any, association between antioxidant vitamin intake and better cognitive function in middle-aged adults. |
| DOI | 10.1017/s1368980000000380 |
| Alternate Journal | Public Health Nutr |
| PubMed ID | 10980106 |
| Grant List | N01HC55015 / HC / NHLBI NIH HHS / United States N01HC55016 / HC / NHLBI NIH HHS / United States N01HC55018 / HC / NHLBI NIH HHS / United States |