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Pulse pressure and age at menopause.

TitlePulse pressure and age at menopause.
Publication TypeJournal Article
Year of Publication2002
AuthorsLuoto R, A Sharrett R, Eigenbrodt M, Arnett D
JournalBMC Womens Health
Date Published2002 Jun 28

BACKGROUND: The objective of this study was to study the association of early age at menopause with pulse pressure (PP), a marker of arterial stiffness, and PP change. METHODS: The effect of natural menopause was studied in 2484 women from the Atherosclerosis Risk in Communities (ARIC) Study who had not used hormone replacement therapy and who had not had a hysterectomy. The cross-sectional association of age with PP was evaluated in the entire cohort. The cross-sectional association of recalled age at menopause was evaluated in the 1688 women who were postmenopausal at baseline. PP change over 6 years was assessed in relation to menopausal age separately in women who were postmenopausal at baseline and in those whose menopause occurred during the 6-year interval. RESULTS: Chronological age was strongly and positively associated with PP in cross-sectional analyses, but not independently associated with PP change. While menopausal age was not associated cross-sectionally with PP, early age at menopause (age

Alternate JournalBMC Womens Health
PubMed ID12088509
PubMed Central IDPMC117223