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Ethnicity and unprovoked hypokalemia in the Atherosclerosis Risk in Communities Study.

TitleEthnicity and unprovoked hypokalemia in the Atherosclerosis Risk in Communities Study.
Publication TypeJournal Article
Year of Publication2002
AuthorsAndrew ME, Jones DW, Wofford MR, Wyatt SB, Schreiner PJ, Brown AC, Young DB, Taylor HA
JournalAm J Hypertens
Volume15
Issue7 Pt 1
Pagination594-9
Date Published2002 Jul
ISSN0895-7061
KeywordsAfrican Continental Ancestry Group, Arteriosclerosis, Cross-Sectional Studies, European Continental Ancestry Group, Female, Humans, Hypertension, Hypokalemia, Male, Middle Aged, Potassium, Prevalence, Risk Factors, Sex Distribution
Abstract

BACKGROUND: Hypertension is more prevalent in the African American population when compared with the European American population in the United States. Unprovoked hypokalemia may lead to hypertension and is associated with several forms of recognized secondary hypertension.

METHODS: We investigated the association of ethnicity with unprovoked hypokalemia in the second Atherosclerosis Risk in Communities (ARIC) study examination. Hypokalemia was defined as serum potassium

RESULTS: A statistically significant association was detected between ethnicity and unprovoked hypokalemia (odds ratio = 5.3; 95% confidence interval = 3.6, 7.7) with unprovoked hypokalemia more prevalent in African Americans both before and after adjustment for important covariates. The unadjusted prevalence for unprovoked hypokalemia was 2.6% for African Americans and 0.5% for European Americans.

CONCLUSIONS: We found that the prevalence of unprovoked hypokalemia for African Americans in the ARIC cohort was more than five times that for European Americans. These data suggest that an increased awareness of hypokalemia and its etiology may be indicated for African Americans.

DOI10.1016/s0895-7061(02)02270-7
Alternate JournalAm J Hypertens
PubMed ID12118905
Grant ListN01-HC-95170 / HC / NHLBI NIH HHS / United States
N01-HC-95171 / HC / NHLBI NIH HHS / United States
N01-HC-95172 / HC / NHLBI NIH HHS / United States
N01-HC-955015 / HC / NHLBI NIH HHS / United States
N01-HC-955016 / HC / NHLBI NIH HHS / United States
N01-HC-955018 / HC / NHLBI NIH HHS / United States
N01-HC-955019 / HC / NHLBI NIH HHS / United States
N01-HC-955020 / HC / NHLBI NIH HHS / United States
N01-HC-955021 / HC / NHLBI NIH HHS / United States
N01-HC-955022 / HC / NHLBI NIH HHS / United States