Pulse lineResearch With Heart Logo

Prevalence of coronary heart disease and carotid arterial thickening in patients with the metabolic syndrome (The ARIC Study).

TitlePrevalence of coronary heart disease and carotid arterial thickening in patients with the metabolic syndrome (The ARIC Study).
Publication TypeJournal Article
Year of Publication2004
AuthorsMcNeill A M, Rosamond WD, Girman CJ, Heiss G, Golden S H, Duncan BB, East HE, Ballantyne C
JournalAm J Cardiol
Volume94
Issue10
Pagination1249-54
Date Published2004 Nov 15
ISSN0002-9149
KeywordsCarotid Artery Diseases, Coronary Disease, Cross-Sectional Studies, Female, Humans, Male, Metabolic Syndrome, Middle Aged, Prevalence, Risk Factors, Tunica Intima, Tunica Media, Ultrasonography
Abstract

We determined the prevalence of the metabolic syndrome (MS) with the criteria recommended by the National Cholesterol and Education Program, Adult Treatment Panel III report and estimated the magnitude of cross-sectional associations between the MS, coronary heart disease (CHD), and atherosclerosis in 14,502 black and white middle-age patients in the Atherosclerosis Risk in Communities Study. CHD was ascertained by standardized procedures and subclinical atherosclerosis was determined by measuring carotid intimal medial wall thickness using B-mode ultrasonography. The prevalence of MS was 30%, with substantial variation across race and gender subgroups. Among women but not among men, MS was significantly associated with increasing low-density lipoprotein cholesterol. CHD prevalence was 7.4% among those with the MS compared with 3.6% in comparison subjects (p

DOI10.1016/j.amjcard.2004.07.107
Alternate JournalAm J Cardiol
PubMed ID15541239
Grant List5-T32-HL07055 / HL / NHLBI NIH HHS / United States
N01-HC-55015 / HC / NHLBI NIH HHS / United States
N01-HC-55016 / HC / NHLBI NIH HHS / United States
N01-HC-55018 / HC / NHLBI NIH HHS / United States
N01-HC-55019 / HC / NHLBI NIH HHS / United States
N01-HC-55020 / HC / NHLBI NIH HHS / United States
N01-HC-55021 / HC / NHLBI NIH HHS / United States
N01-HC-55022 / HC / NHLBI NIH HHS / United States