|Title||Lung function and ischemic stroke incidence: the Atherosclerosis Risk in Communities study.|
|Publication Type||Journal Article|
|Year of Publication||2006|
|Authors||Hozawa A, Billings JL, Shahar E, Ohira T, Rosamond WD, Folsom AR|
|Date Published||2006 Dec|
|Keywords||Arteriosclerosis, Blacks, Cerebral Infarction, Cohort Studies, Cross-Sectional Studies, Female, Forced Expiratory Volume, Humans, Incidence, Linear Models, Male, Middle Aged, Prospective Studies, Pulmonary Disease, Chronic Obstructive, Risk Factors, Smoking, Statistics as Topic, Vital Capacity|
BACKGROUND: Few studies have examined the relation between lung function and ischemic stroke incidence; none have studied African Americans.
METHODS: We followed 13,842 middle-aged adults initially free of stroke and coronary heart disease and observed 472 incident ischemic strokes over 13 years. Quartiles of FEV(1) as a percentage of predicted value (FEV(1)PP) and FVC as a percentage of a predicted value (FVCPP) were used as the indicators of lung function.
RESULTS: In the age-, race-, gender-, and education-adjusted models, both lung function measures were significantly inversely related to ischemic stroke incidence (linear trend for FEV(1)PP, p
CONCLUSIONS: Among white subjects, participants with impaired lung function have a modestly higher risk of ischemic stroke even if they have never smoked nor had respiratory symptoms.
|Grant List||N01 HC 55015 / HC / NHLBI NIH HHS / United States |
N01 HC 55016 / HC / NHLBI NIH HHS / United States
N01 HC 55018 / HC / NHLBI NIH HHS / United States
N01 HC 55019 / HC / NHLBI NIH HHS / United States
N01 HC 55020 / HC / NHLBI NIH HHS / United States
N01 HC 55021 / HC / NHLBI NIH HHS / United States
N01 HC 55022 / HC / NHLBI NIH HHS / United States