Pulse lineResearch With Heart Logo

Kidney function and risk of peripheral arterial disease: results from the Atherosclerosis Risk in Communities (ARIC) Study.

TitleKidney function and risk of peripheral arterial disease: results from the Atherosclerosis Risk in Communities (ARIC) Study.
Publication TypeJournal Article
Year of Publication2007
AuthorsWattanakit K, Folsom AR, Selvin E, Coresh J, Hirsch AT, Weatherley BD
JournalJ Am Soc Nephrol
Volume18
Issue2
Pagination629-36
Date Published2007 Feb
ISSN1046-6673
KeywordsAging, Atherosclerosis, Creatinine, Diabetes Mellitus, Female, Glomerular Filtration Rate, Humans, Incidence, Kidney Failure, Chronic, Kidney Function Tests, Lipids, Male, Peripheral Vascular Diseases, Regression Analysis, Risk, Risk Factors, Smoking, United States
Abstract

Chronic kidney disease (CKD) is associated with an increased risk for cardiovascular disease, but its association with peripheral arterial disease (PAD) is unclear. With the use of data from the Atherosclerosis Risk in Communities (ARIC) Study, 14,280 middle-aged adults were categorized on the basis of estimated GFR >/=90, 60 to 89, and 15 to 59 ml/min per 1.73 m(2) for normal kidney function, mildly decreased kidney function, and stages 3 to 4 CKD, respectively. Incident PAD was defined as a new onset of ankle-brachial index

DOI10.1681/ASN.2005111204
Alternate JournalJ Am Soc Nephrol
PubMed ID17215445
Grant ListN01-HC-55015 / HC / NHLBI NIH HHS / United States
N01-HC-55016 / HC / NHLBI NIH HHS / United States
N01-HC-55018 / HC / NHLBI NIH HHS / United States
N01-HC-55019 / HC / NHLBI NIH HHS / United States
N01-HC-55020 / HC / NHLBI NIH HHS / United States
N01-HC-55021 / HC / NHLBI NIH HHS / United States
N01-HC-55022 / HC / NHLBI NIH HHS / United States
T32-HL-07024 / HL / NHLBI NIH HHS / United States
T32-HL-07779 / HL / NHLBI NIH HHS / United States