| Title | A prospective study of plasma ferritin level and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study. |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Jehn ML, Guallar E, Clark JM, Couper D, Duncan BB, Ballantyne CM, Hoogeveen RC, Harris LZ, Pankow JS |
| Journal | Am J Epidemiol |
| Volume | 165 |
| Issue | 9 |
| Pagination | 1047-54 |
| Date Published | 2007 May 01 |
| ISSN | 0002-9262 |
| Keywords | Arteriosclerosis, Body Mass Index, Case-Control Studies, Diabetes Mellitus, Type 2, Female, Ferritins, Humans, Incidence, Iron Overload, Male, Middle Aged, Proportional Hazards Models, Prospective Studies, Risk Assessment, Risk Factors, United States |
| Abstract | The authors performed a case-cohort study nested within the Atherosclerosis Risk in Communities (ARIC) Study to determine the association between plasma ferritin level and risk of type 2 diabetes mellitus. Persons with incident cases of type 2 diabetes diagnosed over an average follow-up period of 7.9 years (n = 599) were compared with a random sample of the cohort (n = 690). After adjustment for age, gender, menopausal status, ethnicity, center, smoking, and alcohol intake, the hazard ratio for diabetes, comparing the fifth quintile of ferritin with the first quintile, was 1.74 (95% confidence interval: 1.14, 2.65; p-trend |
| DOI | 10.1093/aje/kwk093 |
| Alternate Journal | Am J Epidemiol |
| PubMed ID | 17284722 |
| Grant List | N01-HC-55015 / HC / NHLBI NIH HHS / United States N01-HC-55016 / HC / NHLBI NIH HHS / United States N01-HC-55018 / HC / NHLBI NIH HHS / United States N01-HC-55019 / HC / NHLBI NIH HHS / United States N01-HC-55020 / HC / NHLBI NIH HHS / United States N01-HC-55021 / HC / NHLBI NIH HHS / United States N01-HC-55022 / HC / NHLBI NIH HHS / United States |