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Dietary intake and the development of the metabolic syndrome: the Atherosclerosis Risk in Communities study.

TitleDietary intake and the development of the metabolic syndrome: the Atherosclerosis Risk in Communities study.
Publication TypeJournal Article
Year of Publication2008
AuthorsLutsey PL, Steffen LM, Stevens J
JournalCirculation
Volume117
Issue6
Pagination754-61
Date Published2008 Feb 12
ISSN1524-4539
KeywordsCohort Studies, Dairy Products, Diet, Diet Records, Diet Surveys, Factor Analysis, Statistical, Female, Humans, Male, Meat, Metabolic Syndrome, Middle Aged, Proportional Hazards Models, Surveys and Questionnaires
Abstract

BACKGROUND: The role of diet in the origin of metabolic syndrome (MetSyn) is not well understood; thus, we sought to evaluate the relationship between incident MetSyn and dietary intake using prospective data from 9514 participants (age, 45 to 64 years) enrolled in the Atherosclerosis Risk in Communities (ARIC) study.

METHODS AND RESULTS: Dietary intake was assessed at baseline via a 66-item food frequency questionnaire. We used principal-components analysis to derive "Western" and "prudent" dietary patterns from 32 food groups and evaluated 10 food groups used in previous studies of the ARIC cohort. MetSyn was defined by American Heart Association guidelines. Proportional-hazards regression was used. Over 9 years of follow-up, 3782 incident cases of MetSyn were identified. After adjustment for demographic factors, smoking, physical activity, and energy intake, consumption of a Western dietary pattern (P(trend)=0.03) was adversely associated with incident MetSyn. After further adjustment for intake of meat, dairy, fruits and vegetables, refined grains, and whole grains, analysis of individual food groups revealed that meat (P(trend)

CONCLUSIONS: These prospective findings suggest that consumption of a Western dietary pattern, meat, and fried foods promotes the incidence of MetSyn, whereas dairy consumption provides some protection. The diet soda association was not hypothesized and deserves further study.

DOI10.1161/CIRCULATIONAHA.107.716159
Alternate JournalCirculation
PubMed ID18212291
Grant ListN01-HC-55015 / HC / NHLBI NIH HHS / United States
N01-HC-55016 / HC / NHLBI NIH HHS / United States
N01-HC-55018 / HC / NHLBI NIH HHS / United States
N01-HC-55019 / HC / NHLBI NIH HHS / United States
N01-HC-55020 / HC / NHLBI NIH HHS / United States
N01-HC-55021 / HC / NHLBI NIH HHS / United States
N01-HC-55022 / HC / NHLBI NIH HHS / United States
T32 HL007779 / HL / NHLBI NIH HHS / United States