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Military combat and risk of coronary heart disease and ischemic stroke in aging men: The Atherosclerosis Risk in Communities (ARIC) study.

TitleMilitary combat and risk of coronary heart disease and ischemic stroke in aging men: The Atherosclerosis Risk in Communities (ARIC) study.
Publication TypeJournal Article
Year of Publication2010
AuthorsJohnson AM, Rose KM, Elder GH, Chambless LE, Kaufman JS, Heiss G
JournalAnn Epidemiol
Volume20
Issue2
Pagination143-50
Date Published2010 Feb
ISSN1873-2585
KeywordsAfrican Americans, Combat Disorders, Coronary Disease, European Continental Ancestry Group, Humans, Ischemic Attack, Transient, Longitudinal Studies, Male, Middle Aged, Risk Factors, Socioeconomic Factors, United States, Veterans
Abstract

PURPOSE: To assess the long-term association of military combat stress with coronary heart disease (CHD) and ischemic stroke (IS).

METHODS: The association between exposure to military combat and the occurrence of CHD and IS was assessed among 5,347 men in the Atherosclerosis Risk in Communities (ARIC) study. Outcomes were assessed an average of 36 years after entry into military service during the eras of World War II, the Korean War, and the Vietnam conflict.

RESULTS: Veterans were more likely to be older, white, and of higher socioeconomic status than non-veterans. No differences in CHD period prevalence rates were noted among the three exposure groups, overall or by era of service. Associations between combat and ischemic stroke period prevalence may be modified by father's education, although confidence intervals were wide and event rates small.

CONCLUSIONS: Overall, middle-aged veterans with distant combat exposure are not at increased cardiovascular risk compared to those without combat exposure.

DOI10.1016/j.annepidem.2009.10.006
Alternate JournalAnn Epidemiol
PubMed ID20123165
PubMed Central IDPMC2818420
Grant ListN01HC55020 / HL / NHLBI NIH HHS / United States
R21 HL080422-01A1 / HL / NHLBI NIH HHS / United States
R01 HL064142-04 / HL / NHLBI NIH HHS / United States
N01-HC-55022 / HC / NHLBI NIH HHS / United States
R01 HL064142 / HL / NHLBI NIH HHS / United States
R01-HL064142 / HL / NHLBI NIH HHS / United States
N01-HC-55016 / HC / NHLBI NIH HHS / United States
N01 HC055018 / HC / NHLBI NIH HHS / United States
N01HC55022 / HL / NHLBI NIH HHS / United States
T32-HL07055-27 / HL / NHLBI NIH HHS / United States
R21 HL080422-02 / HL / NHLBI NIH HHS / United States
N01-HC-55021 / HC / NHLBI NIH HHS / United States
N01HC55015 / HL / NHLBI NIH HHS / United States
N01-HC-55019 / HC / NHLBI NIH HHS / United States
N01-HC-55015 / HC / NHLBI NIH HHS / United States
R21 HL080422 / HL / NHLBI NIH HHS / United States
N01-HC-55020 / HC / NHLBI NIH HHS / United States
N01HC55016 / HL / NHLBI NIH HHS / United States
R21-HL080422-01 / HL / NHLBI NIH HHS / United States
N01HC55019 / HL / NHLBI NIH HHS / United States
R24 HD050924 / HD / NICHD NIH HHS / United States
N01HC55021 / HL / NHLBI NIH HHS / United States
T32 HL007055 / HL / NHLBI NIH HHS / United States
T32 HL007055-27 / HL / NHLBI NIH HHS / United States