Title | Evaluation of a novel isotope biomarker for dietary consumption of sweets. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Yeung EH, Saudek CD, Jahren HA, Kao W H L, Islas M, Kraft R, Coresh J, Anderson CAM |
Journal | Am J Epidemiol |
Volume | 172 |
Issue | 9 |
Pagination | 1045-52 |
Date Published | 2010 Nov 01 |
ISSN | 1476-6256 |
Keywords | Aged, Aged, 80 and over, Algorithms, Atherosclerosis, Beverages, Biomarkers, Body Mass Index, Body Weight, Carbon Isotopes, Cross-Sectional Studies, Diet Surveys, Dietary Sucrose, District of Columbia, Energy Intake, Female, Food Analysis, Food Preferences, Humans, Male, Maryland, Middle Aged, Nutrition Assessment, Obesity, Surveys and Questionnaires, Sweetening Agents, Waist Circumference, Waist-Hip Ratio |
Abstract | Carbon isotopic signatures ("δ¹³C") might reflect consumption of corn- and cane-based sweeteners. The authors hypothesized that the δ¹³C value of human serum is higher for individuals with high versus low intakes of corn- and cane-based sweeteners (measured as sweetened beverage intake). They conducted a cross-sectional study within the Atherosclerosis Risk in Communities Magnetic Resonance Imaging study (Maryland, 2005-2006). Diet was assessed by food frequency questionnaire, and blinded serum samples were assayed by natural abundance stable isotope mass spectroscopy. Studied were 186 participants (53% male; mean age, 71 years; mean body mass index, 30 kg/m²). Serum δ¹³C values for individuals with high sweetened beverage intakes were significantly higher than for those with low intakes (-19.15‰ vs. -19.47‰, P |
DOI | 10.1093/aje/kwq247 |
Alternate Journal | Am J Epidemiol |
PubMed ID | 20817784 |
PubMed Central ID | PMC2984252 |
Grant List | N01HC55020 / HL / NHLBI NIH HHS / United States K01 DK067207 / DK / NIDDK NIH HHS / United States N01HC55018 / HL / NHLBI NIH HHS / United States DK-67207 / DK / NIDDK NIH HHS / United States N01-HC-55022 / HC / NHLBI NIH HHS / United States N01-HC-55016 / HC / NHLBI NIH HHS / United States N01HC55015 / HL / NHLBI NIH HHS / United States N01-HC-55019 / HC / NHLBI NIH HHS / United States N01-HC-55015 / HC / NHLBI NIH HHS / United States N01HC55019 / HL / NHLBI NIH HHS / United States T32 DK062707 / DK / NIDDK NIH HHS / United States DK-62707 / DK / NIDDK NIH HHS / United States N01HC55022 / HL / NHLBI NIH HHS / United States N01-HC-55021 / HC / NHLBI NIH HHS / United States N01-HC-55020 / HC / NHLBI NIH HHS / United States N01HC55016 / HL / NHLBI NIH HHS / United States N01-HC-55018 / HC / NHLBI NIH HHS / United States N01HC55021 / HL / NHLBI NIH HHS / United States |