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Prognostic significance of serial Q/ST-T changes by the Minnesota Code and Novacode in the Atherosclerosis Risk in Communities (ARIC) study.

TitlePrognostic significance of serial Q/ST-T changes by the Minnesota Code and Novacode in the Atherosclerosis Risk in Communities (ARIC) study.
Publication TypeJournal Article
Year of Publication2012
AuthorsZhang Z-M, Prineas RJ, Soliman EZ, Baggett C
Secondary AuthorsHeiss G
Corporate AuthorsARIC Research Group
JournalEur J Prev Cardiol
Volume19
Issue6
Pagination1430-6
Date Published2012 Dec
ISSN2047-4881
KeywordsCoronary Disease, Electrocardiography, Female, Humans, Hypertrophy, Left Ventricular, Incidence, Male, Middle Aged, Multivariate Analysis, Myocardial Infarction, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Prospective Studies, Risk Assessment, Risk Factors, Signal Processing, Computer-Assisted, Time Factors, United States
Abstract

AIMS: To compare the value of serial electrocardiographic (ECG) changes by the two most widely used ECG classification systems-the Minnesota Code (MC) and Novacode (Nova) for the prediction of subsequent coronary heart disease (CHD) and total mortality.

METHODS AND RESULTS: We studied 12-lead ECGs from 12,477 participants (average age 54 years at baseline; 58% women; 76% non-Hispanic white) in the Atherosclerosis Risk in Communities (ARIC) Study, who were free of CHD at baseline in 1987, had both good-quality ECGs at baseline and at first study-scheduled follow-up visit, and had ECG QRS duration

CONCLUSION: ECG serial change by both MC and Nova are equally valuable predictors for future fatal cardiac events and total mortality and hence equally useful prognostic indicators in clinical trials and epidemiological studies.

DOI10.1177/1741826711426091
Alternate JournalEur J Prev Cardiol
PubMed ID21997257
PubMed Central IDPMC4948579
Grant ListHHSN268201100012C / HL / NHLBI NIH HHS / United States
HHSN268201100005G / HL / NHLBI NIH HHS / United States
N01 HC055018 / HC / NHLBI NIH HHS / United States
HHSN268201100005I / HL / NHLBI NIH HHS / United States
HHSN268201100005C / HL / NHLBI NIH HHS / United States