| Title | Prognostic significance of serial Q/ST-T changes by the Minnesota Code and Novacode in the Atherosclerosis Risk in Communities (ARIC) study. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Zhang Z-M, Prineas RJ, Soliman EZ, Baggett C, Heiss G |
| Corporate Authors | ARIC Research Group |
| Journal | Eur J Prev Cardiol |
| Volume | 19 |
| Issue | 6 |
| Pagination | 1430-6 |
| Date Published | 2012 Dec |
| ISSN | 2047-4881 |
| Keywords | Coronary Disease, Electrocardiography, Female, Humans, Hypertrophy, Left Ventricular, Incidence, Male, Middle Aged, Multivariate Analysis, Myocardial Infarction, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Prospective Studies, Risk Assessment, Risk Factors, Signal Processing, Computer-Assisted, Time Factors, United States |
| Abstract | AIMS: To compare the value of serial electrocardiographic (ECG) changes by the two most widely used ECG classification systems-the Minnesota Code (MC) and Novacode (Nova) for the prediction of subsequent coronary heart disease (CHD) and total mortality. METHODS AND RESULTS: We studied 12-lead ECGs from 12,477 participants (average age 54 years at baseline; 58% women; 76% non-Hispanic white) in the Atherosclerosis Risk in Communities (ARIC) Study, who were free of CHD at baseline in 1987, had both good-quality ECGs at baseline and at first study-scheduled follow-up visit, and had ECG QRS duration CONCLUSION: ECG serial change by both MC and Nova are equally valuable predictors for future fatal cardiac events and total mortality and hence equally useful prognostic indicators in clinical trials and epidemiological studies. |
| DOI | 10.1177/1741826711426091 |
| Alternate Journal | Eur J Prev Cardiol |
| PubMed ID | 21997257 |
| PubMed Central ID | PMC4948579 |
| Grant List | HHSN268201100012C / HL / NHLBI NIH HHS / United States HHSN268201100005G / HL / NHLBI NIH HHS / United States N01 HC055018 / HC / NHLBI NIH HHS / United States HHSN268201100005I / HL / NHLBI NIH HHS / United States HHSN268201100005C / HL / NHLBI NIH HHS / United States |